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Actuate Therapeutics Inc SEC Filings

ACTU NASDAQ

Welcome to our dedicated page for Actuate Therapeutics SEC filings (Ticker: ACTU), a comprehensive resource for investors and traders seeking official regulatory documents including 10-K annual reports, 10-Q quarterly earnings, 8-K material events, and insider trading forms.

Elraglusib’s journey from lab bench to clinic means Actuate Therapeutics’ SEC disclosures are packed with dense data on GSK-3β science, trial cohorts, and cash runway projections—details critical for biotech investors yet hard to digest quickly.

Problem: Finding the latest dose-limiting toxicity update inside a 300-page 10-K or spotting a sudden insider stock sale before a Phase 2 read-out can take hours. Solution: Stock Titan’s AI-powered platform turns every Actuate Therapeutics filing into an executive-level brief. Our engine highlights clinical-trial milestones, R&D spend, and partnership terms, then links them to market-moving events.

Access every document the moment it hits EDGAR: 10-K annual reports, 10-Q quarterly earnings, 8-K material events, S-1 fundraising prospectuses, and real-time Form 4 insider trades. Investors searching for “Actuate Therapeutics insider trading Form 4 transactions” or “Actuate Therapeutics quarterly earnings report 10-Q filing” land here because we answer those questions directly. Want the proxy statement executive compensation breakdown? It’s parsed and summarised. Need “Actuate Therapeutics 8-K material events explained”? Our AI does that, too.

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Rhea-AI Summary

Actuate Therapeutics (NASDAQ:ACTU) entered a $4.7 million private placement with institutional and accredited investors, selling 666,497 common shares at $7.00 and issuing 666,497 cash-only warrants at the same price. Warrants are immediately exercisable and expire 20 days after an FDA milestone (Breakthrough Therapy designation or Phase 2/3 registration pathway feedback), potentially providing another $4.7 million.

Closing is expected by June 30 2025; proceeds earmarked for working capital. Bios 2024 Co-Invest will hold ~49.9 % beneficial ownership post-deal. A Registration Rights Agreement requires ACTU to file a resale shelf by August 9 2025 and meet strict effectiveness deadlines, with liquidated damages for failure.

  • Item 1.01: Securities Purchase & Warrants
  • Item 3.02: Unregistered sales under Reg D
  • Going-concern risk remains despite new funding.
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FAQ

What is the current stock price of Actuate Therapeutics (ACTU)?

The current stock price of Actuate Therapeutics (ACTU) is $5.96 as of June 28, 2025.

What is the market cap of Actuate Therapeutics (ACTU)?

The market cap of Actuate Therapeutics (ACTU) is approximately 138.3M.

What is the core focus of Actuate Therapeutics Inc?

Actuate Therapeutics Inc is focused on developing innovative therapies for high-impact and difficult-to-treat cancers by targeting GSK-3β, an enzyme central to multiple oncogenic pathways.

How does elraglusib work?

Elraglusib is a small molecule inhibitor designed to penetrate cancer cells and disrupt GSK-3β activity, thereby interfering with tumor survival, proliferation, and resistance to conventional therapies. Additionally, it modulates immune checkpoints, enhancing the activation of cytotoxic T cells.

What clinical areas does the company target?

The company targets a range of solid tumors, including pancreatic ductal adenocarcinoma, soft tissue sarcoma, neuroblastoma, and Ewing sarcoma. Each indication is chosen based on the unmet medical need and the mechanistic rationale behind GSK-3β inhibition.

What stage of development is Actuate Therapeutics currently in?

Actuate Therapeutics is a clinical-stage biopharmaceutical company actively engaged in clinical trials to evaluate the safety and efficacy of its lead candidate elraglusib, both as a single agent and in combination with other therapeutic regimens.

How does the company differentiate its approach from conventional cancer therapies?

The company’s approach focuses on the targeted inhibition of GSK-3β to disrupt not only tumor survival pathways but also to enhance innate immune responses. This dual mechanism contrasts with conventional chemotherapies, which often do not address the immunological aspects of tumor resistance.

What are the key benefits of their targeted drug development strategy?

The targeted strategy provides a scientific rationale for addressing the complex biology of cancer by disrupting critical signaling pathways and modulating immune responses. This integrated approach may offer enhanced effectiveness in tumors that are resistant to standard treatment options.

How does Actuate Therapeutics ensure the rigor of its drug development process?

The company leverages robust clinical trials, extensive preclinical research, and collaborative partnerships with leading research institutions. This strategic approach supports a thorough evaluation of safety, efficacy, and mechanistic insights to guide its drug development process.

How does Actuate Therapeutics compare with other companies in the oncology space?

While the oncology field is highly competitive, Actuate Therapeutics differentiates itself through its focus on a novel molecular target, GSK-3β. The company’s commitment to scientific research and clinical validation provides a unique perspective compared to more traditional approaches in cancer therapy.
Actuate Therapeutics Inc

NASDAQ:ACTU

ACTU Rankings

ACTU Stock Data

138.32M
15.84M
18.69%
51.79%
0.4%
Biotechnology
Pharmaceutical Preparations
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United States
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