[144] AGIOS PHARMACEUTICALS, INC. SEC Filing

Rhea-AI Filing Summary

Insider sale notice under Rule 144: This Form 144 records a proposed sale of 200 common shares by an insider through Morgan Stanley Smith Barney LLC on 10/08/2025 with an stated aggregate market value of $8,200.00. The shares were acquired and paid for by stock option exercise on 10/08/2025 with cash payment.

The filer also reported three prior sales by the same person in the past three months: 200 shares on 09/30/2025 for $8,000.00, 200 shares on 08/27/2025 for $8,000.00, and 1,400 shares on 07/10/2025 for $56,000.00, totaling 1,800 shares and $72,000.00 in gross proceeds over three months. The notice includes the standard insider representation about absence of undisclosed material adverse information.

Positive

• Form 144 filed per Rule 144, showing regulatory compliance with insider sale disclosure
• Shares acquired by option exercise and paid in cash, indicating internal funding of acquisition costs

Negative

• Recent insider sales total 1,800 shares in three months, generating $72,000.00 in gross proceeds
• Planned sale on 10/08/2025 continues a pattern of disposition which may be viewed unfavorably by some investors

Insights

Corporate Governance Analyst

TL;DR: Insider exercised options and plans a small sale; recent 3-month sales total 1,800 shares for $72,000.00.

The filing shows a stock option exercise on 10/08/2025 followed by a proposed sale of 200 shares through Morgan Stanley Smith Barney LLC, consistent with Rule 144 disclosure requirements for restricted or control securities. The immediate payment was in cash, indicating the filer covered option exercise cost at acquisition.

The same insider reported three prior sales in the prior three months totaling 1,800 shares ($72,000.00 gross proceeds). This establishes a recent selling pattern that investors may track; the next concrete date disclosed is 10/08/2025 when the 200-share sale is scheduled.

Form 144 Filer Information	UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 144 NOTICE OF PROPOSED SALE OF SECURITIES PURSUANT TO RULE 144 UNDER THE SECURITIES ACT OF 1933
FORM 144

144: Filer Information

Filer CIK
Filer CCC
Is this a LIVE or TEST Filing?	LIVE TEST
Submission Contact Information
Name
Phone
E-Mail Address

144: Issuer Information

Name of Issuer

SEC File Number

Address of Issuer

Phone

Name of Person for Whose Account the Securities are To Be Sold

See the definition of "person" in paragraph (a) of Rule 144. Information is to be given not only as to the person for whose account the securities are to be sold but also as to all other persons included in that definition. In addition, information shall be given as to sales by all persons whose sales are required by paragraph (e) of Rule 144 to be aggregated with sales for the account of the person filing this notice.

Relationship to Issuer

144: Securities Information

Title of the Class of Securities To Be Sold	Name and Address of the Broker	Number of Shares or Other Units To Be Sold	Aggregate Market Value	Number of Shares or Other Units Outstanding	Approximate Date of Sale	Name the Securities Exchange
Common	Morgan Stanley Smith Barney LLC Executive Financial Services 1 New York Plaza 8th Floor New York NY 10004	200	8200.00	58101518	10/08/2025	NASDAQ

Furnish the following information with respect to the acquisition of the securities to be sold and with respect to the payment of all or any part of the purchase price or other consideration therefor:

144: Securities To Be Sold

Title of the Class	Date you Acquired	Nature of Acquisition Transaction	Name of Person from Whom Acquired	Is this a Gift?	Date Donor Acquired	Amount of Securities Acquired	Date of Payment	Nature of Payment *
Common	10/08/2025	Stock Option Exercise	Issuer			200	10/08/2025	Cash

* If the securities were purchased and full payment therefor was not made in cash at the time of purchase, explain in the table or in a note thereto the nature of the consideration given. If the consideration consisted of any note or other obligation, or if payment was made in installments describe the arrangement and state when the note or other obligation was discharged in full or the last installment paid.

Furnish the following information as to all securities of the issuer sold during the past 3 months by the person for whose account the securities are to be sold.

144: Securities Sold During The Past 3 Months

Name and Address of Seller	Title of Securities Sold	Date of Sale	Amount of Securities Sold	Gross Proceeds
DAVID SCADDEN 88 Sidney St. Cambridge MA 02139	Common	09/30/2025	200	8000.00
DAVID SCADDEN 88 Sidney St. Cambridge MA 02139	Common	08/27/2025	200	8000.00
DAVID SCADDEN 88 Sidney St. Cambridge MA 02139	Common	07/10/2025	1400	56000.00

144: Remarks and Signature

Remarks

Date of Notice

Date of Plan Adoption or Giving of Instruction, If Relying on Rule 10b5-1

ATTENTION:

The person for whose account the securities to which this notice relates are to be sold hereby represents by signing this notice that he does not know any material adverse information in regard to the current and prospective operations of the Issuer of the securities to be sold which has not been publicly disclosed. If such person has adopted a written trading plan or given trading instructions to satisfy Rule 10b5-1 under the Exchange Act, by signing the form and indicating the date that the plan was adopted or the instruction given, that person makes such representation as of the plan adoption or instruction date.

Signature

ATTENTION: Intentional misstatements or omission of facts constitute Federal Criminal Violations (See 18 U.S.C. 1001)

FAQ

What does AGIO's Form 144 disclose about the planned sale?

It discloses a proposed sale of 200 common shares through Morgan Stanley Smith Barney on 10/08/2025 with an aggregate market value of $8,200.00.

How were the 200 shares to be sold on 10/08/2025 acquired?

The shares were acquired by a stock option exercise on 10/08/2025 and paid for in cash.

What insider sales by the same person occurred in the past three months?

Three sales: 200 shares on 09/30/2025 ($8,000.00), 200 shares on 08/27/2025 ($8,000.00), and 1,400 shares on 07/10/2025 ($56,000.00), totaling 1,800 shares and $72,000.00.

Who is the broker handling the proposed sale?

The broker named is Morgan Stanley Smith Barney LLC, Executive Financial Services, 1 New York Plaza, 8th Floor, New York, NY 10004.

Does the filing state the insider knows of any undisclosed material adverse information?

Yes. By signing the notice the person represents they do not know of any material adverse information about the issuer that has not been publicly disclosed.