State Street discloses 11.6M shares (4.3%) of AKEBIA

AKEBIA THERAPEUTICS INC Schedule 13G: State Street Corporation reports beneficial ownership of 11,614,006 shares of common stock, representing 4.3% of the class as of 03/31/2026.

Rhea-AI Filing Summary

AKEBIA THERAPEUTICS INC Schedule 13G: State Street Corporation reports beneficial ownership of 11,614,006 shares of common stock, representing 4.3% of the class as of 03/31/2026. The filing lists shared voting power of 11,269,922 and shared dispositive power of 11,614,006.

The filing names affiliated investment management entities and is signed by a State Street officer on 05/12/2026. This is a passive ownership disclosure under Schedule 13G reporting holdings and power classifications.

Insights

Institutional Ownership Analyst

State Street discloses a 4.3% passive stake in AKEBIA as of 03/31/2026.

State Street Corporation reports beneficial ownership of 11,614,006 shares with shared voting power of 11,269,922 and shared dispositive power of 11,614,006. The filing lists affiliated State Street investment vehicles as the reporting subsidiaries.

As a Schedule 13G filing, this reflects ownership disclosure rather than an active transaction. Subsequent filings would show any material changes in share percentages or voting arrangements.

Key Figures

Filing type: Schedule 13G Beneficially owned: 11,614,006 shares Percent of class: 4.3% +3 more

6 metrics

Filing type Schedule 13G Passive ownership disclosure

Beneficially owned 11,614,006 shares Amount beneficially owned as of <date>03/31/2026</date>

Percent of class 4.3% Percent of class as reported on Schedule 13G

Shared voting power 11,269,922 shares Shared voting power reported

Shared dispositive power 11,614,006 shares Shared dispositive power reported

Signature date 05/12/2026 Date signature was executed on the filing

Key Terms

Schedule 13G, Beneficially owned, Shared dispositive power, Investment adviser (IA)

4 terms

Schedule 13G regulatory

"Schedule 13G filing: passive ownership disclosure and reporting thresholds"

A Schedule 13G is a formal document that investors file with the government when they acquire a large ownership stake in a company, usually for investment purposes rather than control. It helps keep the public informed about who owns significant parts of a company's shares, which can influence how the company is managed and how investors make decisions. Filing this schedule is important for transparency and understanding the ownership landscape of publicly traded companies.

Beneficially owned financial

"Amount beneficially owned: 11614006.00 (b) Percent of class: 4.3 %"

Beneficially owned describes securities or assets where a person has the economic rights and control—such as the right to receive dividends and to direct voting—even if legal title is held in another name. Think of it like having the keys and using a car that’s registered to someone else: you get the benefits and make decisions. Investors care because beneficial ownership reveals who truly controls value and voting power, affecting corporate decisions and takeover dynamics.

Shared dispositive power regulatory

"Shared power to dispose or to direct the disposition of: 11,614,006"

Investment adviser (IA) regulatory

"SSGA FUNDS MANAGEMENT, INC. (IA);STATE STREET GLOBAL ADVISORS EUROPE LIMITED (IA)"

An investment adviser (IA) is a person or firm that provides personalized guidance on buying, selling, or holding investments and often manages client portfolios for a fee. Investors should care because an IA has a legal duty to act in the client's best interest—think of them as a navigator who plans and steers your financial journey—so their advice, fee structure and potential conflicts can directly affect returns and financial risk.

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

What does State Street report owning in AKBA?

State Street reports beneficial ownership of 11,614,006 shares of AKBA common stock, equal to 4.3% of the class as of 03/31/2026. The filing lists shared voting and dispositive powers associated with that stake.

Is this a Schedule 13G or 13D filing for AKBA?

This is a Schedule 13G filing, which is used for passive investors to report holdings. The filing indicates passive ownership and lists affiliated State Street investment entities rather than an acquisition intent.

What voting and dispositive powers does State Street report for AKBA?

State Street reports shared voting power of 11,269,922 shares and shared dispositive power of 11,614,006 shares for AKBA common stock in this filing dated 03/31/2026.

When was the Schedule 13G for AKBA signed and by whom?

The Schedule 13G is signed by Elizabeth Schaefer, identified as Senior Vice President and Chief Accounting Officer, with signature date 05/12/2026 on behalf of State Street Corporation.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Accepted by SEC EDGAR 05/12/2026 - 09:45 AM EDT Learn about SEC filing dates

SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13G

UNDER THE SECURITIES EXCHANGE ACT OF 1934

AKEBIA THERAPEUTICS INC

(Name of Issuer)

COMMON STOCK

(Title of Class of Securities)

00972D105

(CUSIP Number)

03/31/2026

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

Rule 13d-1(b)

Rule 13d-1(c)

Rule 13d-1(d)

schemaVersion:

SCHEDULE 13G

CUSIP Number(s): 00972D105

1

Names of Reporting Persons

STATE STREET CORPORATION

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

MASSACHUSETTS

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 11,269,922.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 11,614,006.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

11,614,006.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

4.3 %

12

Type of Reporting Person (See Instructions)

HC

SCHEDULE 13G

Item 1.
(a)	Name of issuer: AKEBIA THERAPEUTICS INC
(b)	Address of issuer's principal executive offices: 245 FIRST STREET SUITE 1100, CAMBRIDGE, MASSACHUSETTS, 02142
Item 2.
(a)	Name of person filing: STATE STREET CORPORATION;
(b)	Address or principal business office or, if none, residence: ONE CONGRESS STREET, SUITE 1, BOSTON MA 02114, UNITED STATES
(c)	Citizenship: MA
(d)	Title of class of securities: COMMON STOCK
(e)	CUSIP Number(s): 00972D105
Item 3.	If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)	Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)	Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)	Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)	Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)	An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)	An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)	A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)	A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)	A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)	A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J), please specify the type of institution:
(k)	Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.	Ownership
(a)	Amount beneficially owned: 11614006.00
(b)	Percent of class: 4.3 %
(c)	Number of shares as to which the person has:
	(i) Sole power to vote or to direct the vote: 0
	(ii) Shared power to vote or to direct the vote: 11,269,922
	(iii) Sole power to dispose or to direct the disposition of: 0
	(iv) Shared power to dispose or to direct the disposition of: 11,614,006
Item 5.	Ownership of 5 Percent or Less of a Class.
	Ownership of 5 percent or less of a class
Item 6.	Ownership of more than 5 Percent on Behalf of Another Person.
	If any other person is known to have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, such securities, a statement to that effect should be included in response to this item and, if such interest relates to more than 5 percent of the class, such person should be identified. A listing of the shareholders of an investment company registered under the Investment Company Act of 1940 or the beneficiaries of employee benefit plan, pension fund or endowment fund is not required. NOT APPLICABLE
Item 7.	Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
	If a parent holding company has filed this schedule, pursuant to Rule 13d-1(b)(ii)(G), so indicate under Item 3(g) and attach an exhibit stating the identity and the Item 3 classification of the relevant subsidiary. If a parent holding company has filed this schedule pursuant to Rule 13d-1(c) or Rule 13d-1(d), attach an exhibit stating the identification of the relevant subsidiary. SSGA FUNDS MANAGEMENT, INC. (IA);STATE STREET GLOBAL ADVISORS EUROPE LIMITED (IA);STATE STREET GLOBAL ADVISORS TRUST COMPANY (IA);
Item 8.	Identification and Classification of Members of the Group.
	If a group has filed this schedule pursuant to §240.13d-1(b)(1)(ii)(K), so indicate under Item 3(k) and attach an exhibit stating the identity and Item 3 classification of each member of the group. If a group has filed this schedule pursuant to §240.13d-1(c) or §240.13d-1(d), attach an exhibit stating the identity of each member of the group. NOT APPLICABLE
Item 9.	Notice of Dissolution of Group.
	Notice of dissolution of a group may be furnished as an exhibit stating the date of the dissolution and that all further filings with respect to transactions in the security reported on will be filed, if required, by members of the group, in their individual capacity. See Item 5. NOT APPLICABLE

Item 10.

Certifications:

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

STATE STREET CORPORATION

Signature:	ELIZABETH SCHAEFER
Name/Title:	SENIOR VICE PRESIDENT, CHIEF ACCOUNTING OFFICER
Date:	05/12/2026