Alnylam director receives stock and option awards

ALNYLAM PHARMACEUTICALS, INC. director Charles Elliott Sigal reported new equity awards and updated holdings.

Rhea-AI Filing Summary

ALNYLAM PHARMACEUTICALS, INC. director Charles Elliott Sigal reported new equity awards and updated holdings. He received 671 restricted stock units (RSUs), each representing a contingent right to one share of common stock, granted at no cash cost. These RSUs vest in full on the first anniversary of the grant date or upon an earlier qualifying retirement or resignation that occurs no more than 90 days before that anniversary. He was also granted a stock option for 1,441 shares of common stock at an exercise price of $298.48 per share, with the same vesting schedule and an expiration date in 2036. After these awards, he holds 1,446 common shares directly and 2,000 shares indirectly through Sigal Family Investments, LLC.

Insider Trade Summary

Grant/Award: 2,112 shares

Grant/Award 3 txns

Insider Sigal Charles Elliott

Role Director

Type	Security	Shares	Price	Value
Grant/Award	Stock Option (Right to Buy)	1,441	$0.00	$0.00
Grant/Award	Common Stock	671	$0.00	$0.00
holding	Common Stock	--	--	--

Holdings After Transaction: Stock Option (Right to Buy) — 1,441 contracts (Direct); Common Stock — 1,446 shares (Direct); Common Stock — 2,000 shares (Indirect, by Trust)

Footnotes (3)

1. F1. These shares are represented by restricted stock units (RSUs) granted under the Second Amended and Restated 2018 Stock Incentive Plan. Each RSU represents a contingent right to receive one share of common stock. The RSUs will vest in full upon the earlier of the first anniversary of the grant date and the date of any earlier retirement or resignation of the Reporting Person, provided such date of retirement or resignation occurs no more than 90 days prior to the first anniversary of the grant date.
2. F2. Shares held by Sigal Family Investments, LLC, of which the reporting person is Managing Member.
3. F3. The stock option will vest in full upon the earlier of the first anniversary of the grant date and the date of any earlier retirement or resignation of the Reporting Person, provided such date of retirement or resignation occurs no more than 90 days prior to the first anniversary of the grant date.

Key Figures

RSU grant size: 671 RSUs Stock option grant: 1,441 options Option exercise price: $298.48 per share +5 more

8 metrics

RSU grant size 671 RSUs Restricted stock units granted under 2018 Stock Incentive Plan

Stock option grant 1,441 options Right to buy common stock awarded to director

Option exercise price $298.48 per share Conversion or exercise price for 1,441-share option

Direct holdings after grant 1,446 shares Common stock directly owned following the transactions

Indirect holdings 2,000 shares Common stock held via Sigal Family Investments, LLC

RSU vesting date trigger First anniversary of grant Full vesting or earlier qualifying retirement/resignation

Option vesting date trigger First anniversary of grant Same schedule as RSUs for vesting in full

Option expiration 2036-05-20 Expiration date of stock option if not exercised earlier

Key Terms

restricted stock units (RSUs), Second Amended and Restated 2018 Stock Incentive Plan, contingent right to receive one share, stock option, +1 more

5 terms

restricted stock units (RSUs) financial

"These shares are represented by restricted stock units (RSUs) granted under the Second Amended and Restated 2018 Stock Incentive Plan."

Restricted stock units (RSUs) are a type of company promise to give employees shares of stock in the future, usually after certain conditions like working for a set time. They are like a gift promised today that you receive later, which can become valuable if the company's stock price goes up. RSUs matter because they are a way companies reward employees and can be a significant part of compensation.

Second Amended and Restated 2018 Stock Incentive Plan financial

"These shares are represented by restricted stock units (RSUs) granted under the Second Amended and Restated 2018 Stock Incentive Plan."

contingent right to receive one share financial

"Each RSU represents a contingent right to receive one share of common stock."

stock option financial

"The stock option will vest in full upon the earlier of the first anniversary of the grant date..."

A stock option is a contract that gives you the right to buy or sell a company's stock at a specific price within a certain time frame. People use them to potentially make money if the stock's price moves favorably or to protect against losses. It's like holding a coupon that can be used to buy or sell stock at a set price later on.

vesting in full financial

"The RSUs will vest in full upon the earlier of the first anniversary of the grant date..."

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

What equity awards did ALNY director Charles Elliott Sigal receive on this Form 4?

Charles Elliott Sigal received 671 RSUs and a stock option for 1,441 shares. The RSUs convert into common stock on vesting, and the option allows purchase of 1,441 shares at $298.48 per share if exercised after vesting.

How do the new RSUs for ALNY director Charles Elliott Sigal vest?

The 671 RSUs vest in full after one year or certain earlier departures. They vest on the first anniversary of the grant date, or upon earlier retirement or resignation that occurs no more than 90 days before that anniversary, if that condition is met.

What are the key terms of Charles Elliott Sigal’s new stock option at Alnylam (ALNY)?

The stock option covers 1,441 shares at a $298.48 exercise price. It vests in full after one year or a qualifying earlier retirement or resignation, and it remains exercisable until its expiration date in 2036, subject to plan terms.

What are Charles Elliott Sigal’s reported ALNY share holdings after these transactions?

After the awards, Sigal holds 1,446 shares directly and 2,000 shares indirectly. The indirect shares are held through Sigal Family Investments, LLC, where he is the managing member, while the direct holdings reflect common stock in his own name.

Are Charles Elliott Sigal’s new ALNY equity awards open-market purchases or compensation grants?

The Form 4 shows the awards as compensation-related grants, not market buys. Both the 671 RSUs and the 1,441-share stock option are coded as grants or awards, with a zero dollar transaction price per share at grant.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Accepted by SEC EDGAR 05/22/2026 - 04:20 PM Learn about SEC filing dates

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Sigal Charles Elliott

(Last) (First) (Middle)

675 WEST KENDALL STREET

(Street)

CAMBRIDGE MASSACHUSETTS 02142

(City) (State) (Zip)

UNITED STATES

(Country)

2. Issuer Name and Ticker or Trading Symbol
ALNYLAM PHARMACEUTICALS, INC. [ ALNY ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director		10% Owner
	Officer (give title below)		Other (specify below)

2a. Foreign Trading Symbol

3. Date of Earliest Transaction (Month/Day/Year)
05/20/2026

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	05/20/2026		A		671(1)	A	$0	1,446	D
Common Stock								2,000	I	by Trust(2)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Stock Option (Right to Buy)	$298.48	05/20/2026		A		1,441		05/20/2027(3)	05/20/2036	Common Stock	1,441	$0	1,441	D

Explanation of Responses:

1. These shares are represented by restricted stock units (RSUs) granted under the Second Amended and Restated 2018 Stock Incentive Plan. Each RSU represents a contingent right to receive one share of common stock. The RSUs will vest in full upon the earlier of the first anniversary of the grant date and the date of any earlier retirement or resignation of the Reporting Person, provided such date of retirement or resignation occurs no more than 90 days prior to the first anniversary of the grant date.

2. Shares held by Sigal Family Investments, LLC, of which the reporting person is Managing Member.

3. The stock option will vest in full upon the earlier of the first anniversary of the grant date and the date of any earlier retirement or resignation of the Reporting Person, provided such date of retirement or resignation occurs no more than 90 days prior to the first anniversary of the grant date.

	Brett Budzinski, Attorney-in-Fact For: Charles Elliott Sigal	05/22/2026
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)