STOCK TITAN

Alnylam (ALNY) director gets new RSUs, options and reports trust holdings

Filing Impact
(Neutral)
Filing Sentiment
(Neutral)
Form Type
4

Rhea-AI Filing Summary

Alnylam Pharmaceuticals director David E. I. Pyott reported new equity awards and updated holdings. He received 671 restricted stock units, each representing one share of common stock, increasing his direct holdings to 1,582 shares.

He was also granted stock options for 1,441 shares at an exercise price of $298.48 per share, vesting in full on the earlier of one year from grant or certain retirement or resignation conditions. Separately, a trust for which he is trustee holds 27,900 Alnylam shares, reported as indirect ownership.

Positive

  • None.

Negative

  • None.
Insider PYOTT DAVID E I
Role null
Type Security Shares Price Value
Grant/Award Stock Option (Right to Buy) 1,441 $0.00 --
Grant/Award Common Stock 671 $0.00 --
holding Common Stock -- -- --
Holdings After Transaction: Stock Option (Right to Buy) — 1,441 shares (Direct, null); Common Stock — 1,582 shares (Direct, null); Common Stock — 27,900 shares (Indirect, by Trust)
Footnotes (1)
  1. These shares are represented by restricted stock units (RSUs) granted under the Second Amended and Restated 2018 Stock Incentive Plan. Each RSU represents a contingent right to receive one share of common stock. The RSUs will vest in full upon the earlier of the first anniversary of the grant date and the date of any earlier retirement or resignation of the Reporting Person, provided such date of retirement or resignation occurs no more than 90 days prior to the first anniversary of the grant date. The shares of ALNY common stock were purchased by the David E I Pyott Trust, of which the reporting person is trustee. The stock option will vest in full upon the earlier of the first anniversary of the grant date and the date of any earlier retirement or resignation of the Reporting Person, provided such date of retirement or resignation occurs no more than 90 days prior to the first anniversary of the grant date.
RSUs granted 671 RSUs Restricted stock units granted to director on May 20, 2026
Options granted 1,441 options Stock options awarded on May 20, 2026
Option exercise price $298.48 per share Exercise price for 1,441 stock options
Direct shares after award 1,582 shares Alnylam common stock directly held by Pyott after grants
Indirect trust holdings 27,900 shares Alnylam common stock held by David E I Pyott Trust
Option expiration May 20, 2036 Expiration date of granted stock options
restricted stock units (RSUs) financial
"These shares are represented by restricted stock units (RSUs) granted under the Second Amended and Restated 2018 Stock Incentive Plan."
Restricted stock units (RSUs) are a type of company promise to give employees shares of stock in the future, usually after certain conditions like working for a set time. They are like a gift promised today that you receive later, which can become valuable if the company's stock price goes up. RSUs matter because they are a way companies reward employees and can be a significant part of compensation.
Second Amended and Restated 2018 Stock Incentive Plan financial
"These shares are represented by restricted stock units (RSUs) granted under the Second Amended and Restated 2018 Stock Incentive Plan."
Stock Option (Right to Buy) financial
"Stock Option (Right to Buy) listed as a derivative security with an exercise price."
trustee financial
"The shares of ALNY common stock were purchased by the David E I Pyott Trust, of which the reporting person is trustee."
A trustee is a person or institution legally appointed to hold and manage assets or enforce an agreement on behalf of other people (beneficiaries). Think of a trustee as a neutral referee or custodian who must act in the beneficiaries’ best interests, follow the trust or contract rules, and handle distributions, recordkeeping and enforcement. Investors care because a trustworthy trustee protects their rights, ensures promised payments or remedies are delivered, and can influence recoveries if things go wrong.
SEC Form 4
FORM 4UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number:3235-0287
Estimated average burden
hours per response:0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
PYOTT DAVID E I

(Last)(First)(Middle)
675 WEST KENDALL STREET

(Street)
CAMBRIDGE MASSACHUSETTS 02142

(City)(State)(Zip)

UNITED STATES

(Country)
2. Issuer Name and Ticker or Trading Symbol
ALNYLAM PHARMACEUTICALS, INC. [ ALNY ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
XDirector10% Owner
Officer (give title below)Other (specify below)
2a. Foreign Trading Symbol
3. Date of Earliest Transaction (Month/Day/Year)
05/20/2026
6. Individual or Joint/Group Filing (Check Applicable Line)
XForm filed by One Reporting Person
Form filed by More than One Reporting Person
4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year)2A. Deemed Execution Date, if any (Month/Day/Year)3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeVAmount(A) or (D)Price
Common Stock05/20/2026A671(1)A$01,582D
Common Stock27,900Iby Trust(2)
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year)3A. Deemed Execution Date, if any (Month/Day/Year)4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year)7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Stock Option (Right to Buy)$298.4805/20/2026A1,44105/20/2027(3)05/20/2036Common Stock1,441$01,441D
Explanation of Responses:
1. These shares are represented by restricted stock units (RSUs) granted under the Second Amended and Restated 2018 Stock Incentive Plan. Each RSU represents a contingent right to receive one share of common stock. The RSUs will vest in full upon the earlier of the first anniversary of the grant date and the date of any earlier retirement or resignation of the Reporting Person, provided such date of retirement or resignation occurs no more than 90 days prior to the first anniversary of the grant date.
2. The shares of ALNY common stock were purchased by the David E I Pyott Trust, of which the reporting person is trustee.
3. The stock option will vest in full upon the earlier of the first anniversary of the grant date and the date of any earlier retirement or resignation of the Reporting Person, provided such date of retirement or resignation occurs no more than 90 days prior to the first anniversary of the grant date.
Brett Budzinski, Attorney-in-Fact For: David E.I. Pyott05/22/2026
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)

FAQ

What insider transactions did David E. I. Pyott report at Alnylam (ALNY)?

David E. I. Pyott reported equity awards, not market trades. He received 671 restricted stock units and stock options for 1,441 shares, and now directly holds 1,582 shares, with an additional 27,900 shares held indirectly through a trust he oversees.

How many Alnylam (ALNY) RSUs were granted to director David E. I. Pyott?

He was granted 671 restricted stock units in Alnylam common stock. Each RSU equals one share, and the award vests in full on the earlier of the first anniversary of the grant date or qualifying retirement or resignation within the specified 90-day window.

What are the terms of David E. I. Pyott’s new Alnylam (ALNY) stock options?

He received stock options for 1,441 shares with a $298.48 exercise price. These options vest in full on the earlier of one year from grant or certain retirement or resignation timing, and they expire in 2036 if not exercised before the expiration date noted.

How many Alnylam (ALNY) shares does David E. I. Pyott now hold directly and indirectly?

After the reported awards, he directly holds 1,582 Alnylam common shares. In addition, a trust for which he serves as trustee holds 27,900 shares, which are reported as indirect ownership, reflecting his trustee role over that separate entity’s holdings.

Were there any Alnylam (ALNY) share purchases or sales in this Form 4 filing?

The Form 4 shows equity grants and existing holdings, not open-market trades. It reports awards of RSUs and options to David E. I. Pyott and an indirect trust position, with no coded buy or sell transactions disclosed in the summarized transaction data.