STOCK TITAN

Alnylam (NASDAQ: ALNY) CEO granted stock awards and automatic tax-cover share sales

Filing Impact
(Very High)
Filing Sentiment
(Negative)
Form Type
4

Rhea-AI Filing Summary

ALNYLAM PHARMACEUTICALS, INC. reported multiple equity transactions for Chief Executive Officer Yvonne Greenstreet. She received a grant of 30,425 stock options and 110,746 stock price performance stock units, both at a price of $0.00 per share. She also acquired 13,844 shares of common stock, including restricted stock units under the 2018 Stock Incentive Plan that vest over three years and shares acquired through the company’s 401(k) matching program. On the same date, a total of 6,799 shares of common stock were sold in a series of market transactions at weighted average prices around $323–$333 per share, which the company indicates were automatically sold to cover minimum statutory tax withholding obligations on the awards. Following these transactions, she directly held 98,628 shares of common stock and maintained additional indirect ownership through a managed account, and the performance units may vest on December 31, 2029 depending on future stock price performance.

Positive

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Insider Greenstreet Yvonne
Role Chief Executive Officer
Sold 6,799 shs ($2.23M)
Type Security Shares Price Value
Grant/Award Stock Option (right to buy) 30,425 $0.00 --
Grant/Award Stock Price Performance Stock Unit 110,746 $0.00 --
Grant/Award Common Stock 13,844 $0.00 --
Sale Common Stock 200 $323.62 $65K
Sale Common Stock 382 $324.65 $124K
Sale Common Stock 1,098 $325.63 $358K
Sale Common Stock 1,669 $326.81 $545K
Sale Common Stock 1,399 $327.67 $458K
Sale Common Stock 424 $328.71 $139K
Sale Common Stock 722 $329.71 $238K
Sale Common Stock 346 $330.85 $114K
Sale Common Stock 399 $331.93 $132K
Sale Common Stock 160 $332.64 $53K
holding Common Stock -- -- --
Holdings After Transaction: Stock Option (right to buy) — 30,425 shares (Direct); Stock Price Performance Stock Unit — 110,746 shares (Direct); Common Stock — 105,427 shares (Direct); Common Stock — 407 shares (Indirect, by Managed Account)
Footnotes (1)
  1. These shares are represented by restricted stock units (RSUs) granted under the Second Amended and Restated 2018 Stock Incentive Plan. Each RSU represents a contingent right to receive one share of common stock. The RSUs will vest over a three-year period, with one third vesting on each of the first, second and third anniversaries of the grant date, subject to the Reporting Persons continuous service with the Issuer as of each such vesting date. Represents shares automatically sold by the Company on behalf of the reporting person pursuant to a mandatory sell-to-cover provision in the award agreement to cover minimum statutory tax withholding obligations. The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $323.16 to $324.15. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range. The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $324.20 to $325.20. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range. The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $325.21 to $326.21. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range. The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $326.23 to $327.23. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range. The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $327.24 to $328.24. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range. The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $328.28 to $329.26. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range. The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $329.29 to $330.29. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range. The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $330.30 to $331.30. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range. The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $331.32 to $332.31. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range. The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $332.34 to $332.24. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range. Reflects shares of ALNY common stock acquired by the Reporting Person under the issuer 401(k) plan as a result of the issuer 401(k) matching contribution program. The stock option vests as to 25% of the shares on the first anniversary of the grant date and the remaining shares vest in equal installments at the end of each successive three-month period thereafter until the fourth anniversary of the grant date, subject to the Reporting Persons continuous service with the Issuer as of each such vesting date. Stock price performance unit award (PSU) granted pursuant to the Second Amended and Restated 2018 Stock Incentive Plan. The amount reported is the maximum number of PSUs that may be earned upon achievement of pre-set stock price thresholds. Subject to the terms and conditions of the PSU award agreement, the PSU vests on December 31, 2029 (Vesting Date) and between 50% and 200% of the target number of 55,373 PSUs may be earned if the highest average closing price that is achieved over a 30 consecutive trading period (Future Average Stock Price) in the six months preceding the vesting date (Measurement Period) meets or exceeds certain thresholds. If the Future Average Stock Price does not meet or exceed the baseline threshold price during the Measurement Period, no portion of the PSU will be earned, and all PSUs will be forfeited on the Vesting Date.
SEC Form 4
FORM 4 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number: 3235-0287
Estimated average burden
hours per response: 0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
Greenstreet Yvonne

(Last) (First) (Middle)
675 WEST KENDALL STREET
HENRI A. TERMEER SQUARE

(Street)
CAMBRIDGE MA 02142

(City) (State) (Zip)
2. Issuer Name and Ticker or Trading Symbol
ALNYLAM PHARMACEUTICALS, INC. [ ALNY ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
X Director 10% Owner
X Officer (give title below) Other (specify below)
Chief Executive Officer
3. Date of Earliest Transaction (Month/Day/Year)
03/02/2026
4. If Amendment, Date of Original Filed (Month/Day/Year)
6. Individual or Joint/Group Filing (Check Applicable Line)
X Form filed by One Reporting Person
Form filed by More than One Reporting Person
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 03/02/2026 A 13,844(1) A $0.0 105,427 D
Common Stock 03/02/2026 S(2) 200 D $323.62(3) 105,227 D
Common Stock 03/02/2026 S(2) 382 D $324.65(4) 104,845 D
Common Stock 03/02/2026 S(2) 1,098 D $325.63(5) 103,747 D
Common Stock 03/02/2026 S(2) 1,669 D $326.81(6) 102,078 D
Common Stock 03/02/2026 S(2) 1,399 D $327.67(7) 100,679 D
Common Stock 03/02/2026 S(2) 424 D $328.71(8) 100,255 D
Common Stock 03/02/2026 S(2) 722 D $329.71(9) 99,533 D
Common Stock 03/02/2026 S(2) 346 D $330.85(10) 99,187 D
Common Stock 03/02/2026 S(2) 399 D $331.93(11) 98,788 D
Common Stock 03/02/2026 S(2) 160 D $332.64(12) 98,628 D
Common Stock 407 I by Managed Account(13)
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year) 7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Stock Option (right to buy) $325.07 03/02/2026 A 30,425 (14) 03/02/2036 Common Stock 30,425 $0.0 30,425 D
Stock Price Performance Stock Unit $0.0 03/02/2026 A 110,746 (15) (15) Common Stock 110,746(15) $0.0 110,746 D
Explanation of Responses:
1. These shares are represented by restricted stock units (RSUs) granted under the Second Amended and Restated 2018 Stock Incentive Plan. Each RSU represents a contingent right to receive one share of common stock. The RSUs will vest over a three-year period, with one third vesting on each of the first, second and third anniversaries of the grant date, subject to the Reporting Persons continuous service with the Issuer as of each such vesting date.
2. Represents shares automatically sold by the Company on behalf of the reporting person pursuant to a mandatory sell-to-cover provision in the award agreement to cover minimum statutory tax withholding obligations.
3. The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $323.16 to $324.15. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.
4. The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $324.20 to $325.20. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.
5. The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $325.21 to $326.21. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.
6. The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $326.23 to $327.23. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.
7. The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $327.24 to $328.24. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.
8. The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $328.28 to $329.26. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.
9. The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $329.29 to $330.29. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.
10. The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $330.30 to $331.30. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.
11. The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $331.32 to $332.31. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.
12. The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $332.34 to $332.24. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.
13. Reflects shares of ALNY common stock acquired by the Reporting Person under the issuer 401(k) plan as a result of the issuer 401(k) matching contribution program.
14. The stock option vests as to 25% of the shares on the first anniversary of the grant date and the remaining shares vest in equal installments at the end of each successive three-month period thereafter until the fourth anniversary of the grant date, subject to the Reporting Persons continuous service with the Issuer as of each such vesting date.
15. Stock price performance unit award (PSU) granted pursuant to the Second Amended and Restated 2018 Stock Incentive Plan. The amount reported is the maximum number of PSUs that may be earned upon achievement of pre-set stock price thresholds. Subject to the terms and conditions of the PSU award agreement, the PSU vests on December 31, 2029 (Vesting Date) and between 50% and 200% of the target number of 55,373 PSUs may be earned if the highest average closing price that is achieved over a 30 consecutive trading period (Future Average Stock Price) in the six months preceding the vesting date (Measurement Period) meets or exceeds certain thresholds. If the Future Average Stock Price does not meet or exceed the baseline threshold price during the Measurement Period, no portion of the PSU will be earned, and all PSUs will be forfeited on the Vesting Date.
By: Brett Budzinski, Attorney-in-Fact For: Yvonne Greenstreet 03/04/2026
** Signature of Reporting Person Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What equity awards did ALNY (Alnylam) CEO Yvonne Greenstreet receive in this Form 4?

Yvonne Greenstreet received 30,425 stock options and 110,746 stock price performance stock units at $0.00 per share, plus 13,844 common shares including restricted stock units and 401(k) match shares, all granted as part of her compensation package.

How do the stock price performance units for ALNY’s CEO vest and what are the conditions?

The performance stock units may vest on December 31, 2029, with 50% to 200% of a 55,373-unit target potentially earned if the highest 30-day average closing price in the preceding six months meets preset stock price thresholds; otherwise, all units are forfeited.

Why were ALNY CEO Yvonne Greenstreet’s ALNY shares sold in this Form 4 filing?

The filing states the 6,799 ALNY shares were automatically sold by the company under a mandatory sell-to-cover provision to satisfy minimum statutory tax withholding obligations tied to her equity awards, rather than discretionary open-market sales by the CEO.

At what prices were the ALNY shares sold to cover tax withholding for the CEO?

The 6,799 ALNY shares were sold in multiple transactions at weighted average prices generally between about $323.16 and $332.64 per share, with detailed price ranges for each trade available upon request from the company, any security holder, or SEC staff.

What vesting schedule applies to the ALNY stock options granted to the CEO?

The stock option for 30,425 shares vests 25% on the first anniversary of the grant date, with the remaining shares vesting in equal quarterly installments until the fourth anniversary, contingent on Yvonne Greenstreet’s continuous service with Alnylam through each vesting date.

How many ALNY common shares does the CEO hold directly after these transactions?

After the reported grants and tax-cover sales, Yvonne Greenstreet directly held 98,628 shares of ALNY common stock, with an additional 407 shares held indirectly through a managed account, as reflected in the ownership totals disclosed in the Form 4 data.