Alnylam Pharmaceuticals Inc SEC Filings

Alnylam Pharmaceuticals (ALNY) announced its financial results for the quarter ended September 30, 2025. The company furnished a press release as Exhibit 99.1 with additional details.

The information is furnished under Item 2.02 and is not deemed filed for purposes of Section 18 of the Exchange Act, nor incorporated by reference except as expressly stated.

Alnylam Pharmaceuticals (ALNY) officer Bryan Supran reported acquiring 13,026 shares of common stock via a restricted stock unit (RSU) grant on 10/01/2025. Each RSU represents the right to receive one share. The RSUs vest over three years, with one third vesting on each of the first, second, and third anniversaries of the grant date, contingent on continued service.

Following the reported transaction, 13,026 shares were beneficially owned on a direct basis.

Jeffrey V. Poulton, EVP and Chief Financial Officer of Alnylam Pharmaceuticals (ALNY), reported equity changes tied to performance-based stock units (PSUs) that vested following corporate milestones. On 10/01/2025 the reporting person received 3,108 shares from a 2/24/2021 PSU tranche and 4,644 shares from a 3/01/2024 PSU tranche after the issuer publicly reported initiation of a Phase 3 clinical study in a prevalent indication, as determined by the People, Culture and Compensation Committee.

The company automatically sold 3,821 shares on 10/02/2025 under a mandatory sell-to-cover provision to satisfy statutory tax withholding, at weighted-average prices ranging roughly from $446.19 to $456.09 across multiple transactions. After these transactions the reporting person beneficially owned 54,052 shares directly and 57 shares indirectly via a managed account; 57 additional shares were acquired under the issuer 401(k) matching program.

Alnylam Pharmaceuticals (ALNY) CEO Yvonne Greenstreet reported PSU-related share activity. On 10/01/2025, she acquired 3,860 and 14,252 shares at $0 upon PSU vesting tied to the initiation of a Phase 3 clinical study, as determined by the PC&C Committee. On 10/02/2025, the Company executed sell-to-cover transactions to satisfy tax withholding, with multiple weighted-average sales ranging from $446.53 to $457.64. Following these transactions, she held 65,409 shares directly and 407 shares indirectly by a managed account.

Alnylam Pharmaceuticals (ALNY) executive Tolga Tanguler, EVP and Chief Commercial Officer, reported equity activity on a Form 4. On 10/01/2025, 2,851 common shares were acquired at $0.00 upon vesting of performance-based stock units tied to the initiation of a Phase 3 clinical study, as determined by the Board’s People, Culture and Compensation Committee.

On 10/02/2025, shares were automatically sold by the company under a mandatory sell-to-cover provision to satisfy tax withholding, executed in multiple trades with weighted average prices ranging from $446.19 to $457.64. Following these transactions, the reporting person beneficially owned 27,438 shares directly.

Alnylam Pharmaceuticals (ALNY) EVP Chief R&D Pushkal Garg reported PSU vesting and related share sales. On 10/01/2025, he acquired 3,108 and 2,851 common shares at $0.00 upon vesting tied to the company publicly reporting the initiation of Phase 3 clinical studies, as determined by the Board’s PC&C Committee.

On 10/02/2025, shares were sold automatically to cover taxes from the PSU settlements at disclosed weighted average prices by tranche; additional sales on 10/03/2025 were made under a Rule 10b5‑1(c) trading plan adopted on 09/11/2024. After these transactions, direct holdings were 20,221 shares, with 431 held via a managed account and 250 held in a trust.

Alnylam Pharmaceuticals reported a material event on an Form 8-K that discloses a Credit Agreement dated September 30, 2025 among Alnylam, the lenders party to the agreement, and Bank of America, N.A. acting as Administrative Agent. The filing references an interactive cover page data file embedded within the Inline XBRL document and is signed by Jeffrey V. Poulton, Executive Vice President and Chief Financial Officer. No loan amounts, interest terms, covenants, maturity dates, or other economic details are included in the provided text.

Alnylam Pharmaceuticals (ALNY) filed a Form 144 notifying of a proposed sale of 3,022 common shares with an aggregate market value of $1,362,922.00. The shares are to be sold through UBS Financial Services, Inc. on or about 10/03/2025. The filer states these shares were acquired as PSUs from the issuer on 10/01/2025. The notice also discloses a prior sale by Pushkal Garg of 1,455 shares on 08/19/2025 for gross proceeds of $666,989.17. The filer attests there is no undisclosed material adverse information.

ALNYLAM PHARMACEUTICALS, INC. (ALNY) Form 3 filed for Bryan Supran, who is identified as Executive Vice President, Chief Legal Officer and Secretary. The event date requiring the statement is 09/15/2025. The filing states that no securities are beneficially owned by the reporting person and attaches Exhibit 24 (Power of Attorney). The form is signed by an attorney-in-fact on behalf of Mr. Supran on 09/22/2025.