ALX Oncology Holdings Inc. ownership update: three Millennium-related filers and Integrated Core Strategies report shared beneficial interests in ALX Oncology common stock totaling reported holdings of 730,528 shares (0.5%) for Integrated Core Strategies and 1,988,559 shares (1.5%) for each of Millennium Management LLC, Millennium Group Management LLC and Israel A. Englander.
The filing is a Schedule 13G/A amendment that attaches a Joint Filing Agreement dated April 27, 2026 and explains the securities are held by entities subject to voting or investment discretion by Millennium-affiliated managers; the filing does not admit beneficial ownership by the reporting parties.
Positive
None.
Negative
None.
Insights
Large institutional positions disclosed with shared voting/dispositive power.
The amendment lists 1,988,559 shares (1.5%) for Millennium-related filers and 730,528 shares (0.5%) for Integrated Core Strategies, indicating passive/collective holdings reported under a joint filing arrangement. The filing emphasizes voting and investment discretion exercised through affiliated entities.
Investor impact depends on future actions by those managers; timing and disposition plans are not stated in the excerpt.
Joint filing and attribution language clarifies control relationships, not admissions of ownership.
The form includes a Joint Filing Agreement dated April 27, 2026 and describes that securities are held by entities subject to voting or investment discretion by Millennium Management LLC and related managers. The text cautions against construing this as an admission of beneficial ownership.
Watch subsequent filings for any Form 4/Form 13D changes that would show active acquisition or disposition.
Key Figures
Millennium holdings:1,988,559 sharesIntegrated Core Strategies holdings:730,528 sharesMillennium percentage:1.5%+1 more
4 metrics
Millennium holdings1,988,559 sharesreported for Millennium Management LLC, Millennium Group Management LLC, Israel A. Englander
"Amendment No. 2 ALX Oncology Holdings Inc. Common Stock"
A Schedule 13G/A is an amended public filing with the U.S. securities regulator that updates a previous Schedule 13G, disclosing when an individual or group holds a substantial (typically over 5%) stake in a company and is claiming a passive, non‑controlling intent. Investors monitor these updates because rising or falling holdings can signal changing confidence, potential future moves, or shifts in voting power — like watching a public ledger where large shareholders quietly adjust their positions.
Joint Filing Agreementregulatory
"Exhibit I: Joint Filing Agreement, dated as of April 27, 2026"
Shared Dispositive Powerfinancial
"Shared Dispositive Power 1,988,559.00"
Beneficially ownedregulatory
"Amount beneficially owned: See response to Item 9"
Beneficially owned describes securities or assets where a person has the economic rights and control—such as the right to receive dividends and to direct voting—even if legal title is held in another name. Think of it like having the keys and using a car that’s registered to someone else: you get the benefits and make decisions. Investors care because beneficial ownership reveals who truly controls value and voting power, affecting corporate decisions and takeover dynamics.
What holdings does ALXO Schedule 13G/A disclose for Millennium affiliates?
The filing discloses 1,988,559 shares (1.5%) reported for Millennium Management LLC, Millennium Group Management LLC, and Israel A. Englander. It shows shared voting and dispositive power over those shares held by affiliated entities.
How many shares does Integrated Core Strategies report owning in ALXO?
Integrated Core Strategies reports 730,528 shares (0.5%) with shared voting and dispositive power. The amount is shown on the cover-page response fields in the amendment.
Does the Schedule 13G/A amendment state these parties admit beneficial ownership?
No. The filing explicitly states that the statements should not be construed as an admission by Millennium entities or Mr. Englander of beneficial ownership of the securities held by such entities.
What agreement accompanies the joint filing in the ALXO amendment?
A Joint Filing Agreement dated April 27, 2026 among Integrated Core Strategies (US) LLC, Millennium Management LLC, Millennium Group Management LLC and Israel A. Englander is attached as Exhibit I to the amendment.
Who signed the Schedule 13G/A amendment for ALXO?
Signatures include Gil Raviv, Global General Counsel on behalf of the Millennium-related filers and Israel A. Englander personally, each dated April 27, 2026.
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
SCHEDULE 13G
UNDER THE SECURITIES EXCHANGE ACT OF 1934
(Amendment No. 2)
ALX Oncology Holdings Inc.
(Name of Issuer)
Common Stock, par value $0.001 per share
(Title of Class of Securities)
00166B105
(CUSIP Number)
03/31/2026
(Date of Event Which Requires Filing of this Statement)
Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
Rule 13d-1(b)
Rule 13d-1(c)
Rule 13d-1(d)
schemaVersion:
SCHEDULE 13G
CUSIP Number(s):
00166B105
1
Names of Reporting Persons
Integrated Core Strategies (US) LLC
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
DELAWARE
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
730,528.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
730,528.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
730,528.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
0.5 %
12
Type of Reporting Person (See Instructions)
OO
SCHEDULE 13G
CUSIP Number(s):
00166B105
1
Names of Reporting Persons
Millennium Management LLC
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
DELAWARE
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
1,988,559.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
1,988,559.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
1,988,559.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
1.5 %
12
Type of Reporting Person (See Instructions)
OO
SCHEDULE 13G
CUSIP Number(s):
00166B105
1
Names of Reporting Persons
Millennium Group Management LLC
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
DELAWARE
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
1,988,559.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
1,988,559.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
1,988,559.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
1.5 %
12
Type of Reporting Person (See Instructions)
OO
SCHEDULE 13G
CUSIP Number(s):
00166B105
1
Names of Reporting Persons
Israel A. Englander
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
UNITED STATES
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
1,988,559.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
1,988,559.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
1,988,559.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
1.5 %
12
Type of Reporting Person (See Instructions)
IN
SCHEDULE 13G
Item 1.
(a)
Name of issuer:
ALX Oncology Holdings Inc.
(b)
Address of issuer's principal executive offices:
323 Allerton Avenue, South San Francisco, California 94080
Item 2.
(a)
Name of person filing:
Integrated Core Strategies (US) LLC
Millennium Management LLC
Millennium Group Management LLC
Israel A. Englander
(b)
Address or principal business office or, if none, residence:
Integrated Core Strategies (US) LLC
c/o Millennium Management LLC
399 Park Avenue
New York, New York 10022
Millennium Management LLC
399 Park Avenue
New York, New York 10022
Millennium Group Management LLC
399 Park Avenue
New York, New York 10022
Israel A. Englander
c/o Millennium Management LLC
399 Park Avenue
New York, New York 10022
(c)
Citizenship:
Integrated Core Strategies (US) LLC - Delaware
Millennium Management LLC - Delaware
Millennium Group Management LLC - Delaware
Israel A. Englander - United States
(d)
Title of class of securities:
Common Stock, par value $0.001 per share
(e)
CUSIP No.:
00166B105
Item 3.
If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)
Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)
Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)
Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)
Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)
An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)
An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)
A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)
A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)
A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)
A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J),
please specify the type of institution:
(k)
Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.
Ownership
(a)
Amount beneficially owned:
See response to Item 9 on each cover page.
(b)
Percent of class:
See response to Item 11 on each cover page.
(c)
Number of shares as to which the person has:
(i) Sole power to vote or to direct the vote:
See response to Item 5 on each cover page.
(ii) Shared power to vote or to direct the vote:
See response to Item 6 on each cover page.
(iii) Sole power to dispose or to direct the disposition of:
See response to Item 7 on each cover page.
(iv) Shared power to dispose or to direct the disposition of:
See response to Item 8 on each cover page.
The securities disclosed herein as potentially beneficially owned by Millennium Management LLC, Millennium Group Management LLC and Mr. Englander are held by entities subject to voting control and investment discretion by Millennium Management LLC and/or other investment managers that may be controlled by Millennium Group Management LLC (the managing member of Millennium Management LLC) and Mr. Englander (the sole voting trustee of the managing member of Millennium Group Management LLC). The foregoing should not be construed in and of itself as an admission by Millennium Management LLC, Millennium Group Management LLC or Mr. Englander as to beneficial ownership of the securities held by such entities.
Item 5.
Ownership of 5 Percent or Less of a Class.
Ownership of 5 percent or less of a class
Item 6.
Ownership of more than 5 Percent on Behalf of Another Person.
Not Applicable
Item 7.
Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
Not Applicable
Item 8.
Identification and Classification of Members of the Group.
If a group has filed this schedule pursuant to §240.13d-1(b)(1)(ii)(J), so indicate under Item 3(j) and attach an exhibit stating the identity and Item 3 classification of each member of the group. If a group has filed this schedule pursuant to §240.13d-1(c) or §240.13d-1(d), attach an exhibit stating the identity of each member of the group.
See Exhibit I
Item 9.
Notice of Dissolution of Group.
Not Applicable
Item 10.
Certifications:
By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.
SIGNATURE
After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.
Integrated Core Strategies (US) LLC
Signature:
/s/ Gil Raviv
Name/Title:
Gil Raviv, Global General Counsel
Date:
04/27/2026
Millennium Management LLC
Signature:
/s/ Gil Raviv
Name/Title:
Gil Raviv, Global General Counsel
Date:
04/27/2026
Millennium Group Management LLC
Signature:
/s/ Gil Raviv
Name/Title:
Gil Raviv, Global General Counsel
Date:
04/27/2026
Israel A. Englander
Signature:
/s/ Israel A. Englander
Name/Title:
Israel A. Englander
Date:
04/27/2026
Comments accompanying signature: ** INTEGRATED CORE STRATEGIES (US) LLC
By: Integrated Holding Group LP, its Managing Member
By: Millennium Management LLC, its General Partner
Exhibit Information
Exhibit I: Joint Filing Agreement, dated as of April 27, 2026, by and among Integrated Core Strategies (US) LLC, Millennium Management LLC, Millennium Group Management LLC and Israel A. Englander.
