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Amgen (NASDAQ: AMGN) CTO David Reese to retire as company realigns AI and R&D

Filing Impact
(High)
Filing Sentiment
(Neutral)
Form Type
8-K

Rhea-AI Filing Summary

Amgen Inc. announced that David M. Reese, M.D., executive vice president and Chief Technology Officer, will retire from his executive roles effective June 30, 2026. He will remain an executive vice president until that date and receive retirement benefits under existing company plans.

To support Amgen’s focus on combining biology, data science and advanced technologies, the company is redistributing Reese’s responsibilities effective June 1, 2026. James Bradner, M.D., will serve as executive vice president, Research and Development, Artificial Intelligence and Data; Sean Bruich will become senior vice president and Chief Technology Officer; and Murdo Gordon will lead Amgen Global Markets and Policy as executive vice president. These changes are intended to deepen the integration of science and technology across research, medical, commercial and policy functions.

Positive

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Item 5.02 Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers Governance
Key personnel changes including departures, elections, or appointments of directors and executive officers.
Item 9.01 Financial Statements and Exhibits Exhibits
Financial statements, pro forma financial information, and exhibit attachments filed with this report.
Retirement effective date June 30, 2026 David M. Reese retires as executive vice president and CTO
Role redistribution date June 1, 2026 New responsibilities for Bradner, Gordon, Griffith and Bruich begin
Amgen history More than 45 years Time since Amgen helped establish the biotechnology industry
Index membership 30 companies Amgen is one of 30 in the Dow Jones Industrial Average
convergent innovation technical
"position us to advance what we call convergent innovation and strengthen our ability"
biosimilars medical
"he led approvals of numerous innovative medicines and biosimilars, advanced a robust pipeline"
Biosimilars are medicines made to be highly similar to an already approved biological drug produced from living cells, with no meaningful differences in safety or effectiveness. They matter to investors because they introduce lower‑cost competition to expensive biologic treatments—similar to how generic drugs compete with brand drugs—but involve more complex manufacturing, regulatory review and patent risk, which can affect market share, pricing and profit margins across the sector.
artificial intelligence technical
"advanced technologies such as artificial intelligence to accelerate the discovery and development"
Artificial intelligence is the ability of computers and machines to perform tasks that typically require human thinking, such as understanding language, recognizing patterns, or making decisions. For investors, it matters because AI can enhance efficiency, uncover new insights, and enable smarter strategies, potentially impacting the value and performance of companies that develop or utilize this technology.
forward-looking statements regulatory
"This news release contains forward-looking statements that are based on the current expectations"
Forward-looking statements are predictions or plans that companies share about what they expect to happen in the future, like estimating sales or profits. They matter because they help investors understand a company's outlook, but since they are based on guesses and assumptions, they can sometimes be wrong.
managed care financial
"domestic and international trends toward managed care and healthcare cost containment"
A system in which health insurers, networks, or administrators coordinate who provides care, which services are covered, and how much is paid, often using rules, provider networks, and price negotiations to control costs and quality. Think of it like a subscription service that directs where you go and what is paid for; investors care because it shapes how much hospitals, doctors, drugmakers and device makers can charge, how quickly they get paid, and how many patients they can reach.
product liability claims regulatory
"Our business may be impacted by government investigations, litigation and product liability claims."
false000031815400003181542026-04-222026-04-22

 

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549

 

FORM 8-K

 

CURRENT REPORT

Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

Date of Report (Date of earliest event reported): April 22, 2026

 

 

Amgen Inc.

(Exact name of Registrant as Specified in Its Charter)

 

 

Delaware

001-37702

95-3540776

(State or Other Jurisdiction
of Incorporation)

(Commission File Number)

(IRS Employer
Identification No.)

 

 

 

 

 

One Amgen Center Drive

 

Thousand Oaks, California

 

91320-1799

(Address of Principal Executive Offices)

 

(Zip Code)

 

Registrant’s Telephone Number, Including Area Code: (805) 447-1000

 

 

(Former Name or Former Address, if Changed Since Last Report)

 

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:


Title of each class

 

Trading
Symbol(s)

 


Name of each exchange on which registered

Common stock, $0.0001 par value

 

AMGN

 

The Nasdaq Global Select Market

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§ 230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§ 240.12b-2 of this chapter).

Emerging growth company

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act.

 


Item 5.02 Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.

On April 22, 2026, Amgen Inc. (the “Company”) publicly announced that David M. Reese is retiring from the role of the Company’s Executive Vice President and Chief Technology Officer. To facilitate the further integration of our science, technology and data and build on the strong alignment of our commercial, medical and policy teams, the responsibilities of this role will be redistributed to James E. Bradner, Executive Vice President, Research and Development, Artificial Intelligence and Data, Murdo Gordon, Executive Vice President, Amgen Global Markets and Policy, and Peter H. Griffith, Executive Vice President and Chief Financial Officer, each effective as of June 1, 2026. Dr. Reese will remain employed as an Executive Vice President until his retirement on June 30, 2026.

Departure of Executive Vice President

On June 30, 2026, Dr. Reese will retire from the role of Executive Vice President. At that time, Dr. Reese will be retirement eligible under the Company’s plans and policies and, upon his departure from the Company on June 30, 2026, he will receive the retirement benefits set forth in the Company’s plans and described in the Company’s filings, including the Company’s 2026 Proxy Statement.

Additional Information

A copy of the press release announcing Dr. Reese’s retirement from the role of the Company’s Executive Vice President and Chief Technology Officer is furnished as Exhibit 99.1 to this Current Report on Form 8-K.

The information in Exhibit 99.1 furnished herewith shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liabilities of that section, nor shall it be deemed incorporated by reference into any filings of the Company under the Securities Act of 1933, as amended.

Item 9.01 Financial Statements and Exhibits.

Exhibit

No.

 

Document Description

99.1

 

Press Release dated April 22, 2026.

104

 

Cover Page Interactive Data File (embedded within the Inline XBRL document).

 

 


SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

 

 

 

AMGEN INC.

 

 

 

 

Date:

April 22, 2026

By:

/s/ Jonathan P. Graham

 

 

 

Name: Jonathan P. Graham

 

 

 

Title: Executive Vice President and General Counsel and Secretary
 

 


 

img120286578_0.gif

News Release

One Amgen Center Drive

Thousand Oaks, CA
91320-1799

Telephone 805-447-1000

www.Amgen.com

 

AMGEN ANNOUNCES RETIREMENT OF DAVID M. REESE, EXECUTIVE VICE PRESIDENT AND CHIEF TECHNOLOGY OFFICER

Organizational Changes Further Emphasize Integration of Biology and Technology

 

THOUSAND OAKS, Calif. (April 22, 2026) – Amgen (NASDAQ:AMGN) today announced the retirement of David M. Reese, M.D., executive vice president and Chief Technology Officer, effective June 30, 2026.

 

Reese joined Amgen in 2005 as a clinical development leader in oncology and later served as executive vice president of Research and Development (R&D) from 2018 to 2023. During his tenure, he led approvals of numerous innovative medicines and biosimilars, advanced a robust pipeline of potential new therapies and strengthened discovery research capabilities. As inaugural chief technology officer, Reese encouraged the early adoption of technology and artificial intelligence across all facets of the business, in particular R&D.

 

“Dave recognized early the impact that advances in biology and technology would have on our industry and helped lead Amgen through that shift,” said Robert A. Bradway, chairman and chief executive officer at Amgen. “The capabilities he built position us to advance what we call convergent innovation and strengthen our ability to serve patients in the years ahead.”

 

Convergent innovation brings together biology, data science, and advanced technologies such as artificial intelligence to accelerate the discovery and development of new medicines and transform how patients, providers and other partners engage with the health care system. Amgen is evolving its organization to better connect these interactions with how the company operates. To support this, Amgen is making the following changes effective June 1, 2026:

 

James Bradner, M.D., will serve as executive vice president, Research and Development, Artificial Intelligence and Data. A physician-scientist with expertise at the intersection of biology and technology, Bradner has

AMGEN ANNOUNCES RETIREMENT OF DAVID M. REESE, EXECUTIVE VICE PRESIDENT AND CHIEF TECHNOLOGY OFFICER
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advanced the use of emerging technologies in biomedical research and brings his experience to this next phase at Amgen.
Sean Bruich will serve as senior vice president, Chief Technology Officer. A seasoned technology and data science leader, Bruich has advanced Amgen’s AI and data capabilities, building on a career leading global insights and AI organizations through pivotal moments of industry transformation.
Murdo Gordon will serve as executive vice president, Amgen Global Markets and Policy, which includes Medical, Commercial Operations, Government Affairs and Policy. Gordon brings his experience as a leader of global markets and policy and proven track record of strengthening partnerships with health systems and clinicians to improve access to medicines through the adoption of advanced technologies.
Paul Burton, M.D., Ph.D., will continue to serve as senior vice president, Chief Medical Officer. A champion of medical breakthroughs and public health, Burton remains focused on reaching clinicians and patients with medicines and solutions in areas of greatest unmet need, from cardiovascular to rare diseases.

 

Together, these changes deepen the integration of science and technology and align the organization with the evolving adoption of new technologies across the health care ecosystem, supporting Amgen’s ability to serve more patients around the world.

 

About Amgen

Amgen discovers, develops, manufactures and delivers innovative medicines to fight some of the world’s toughest diseases. Harnessing the best of biology and technology, Amgen reaches millions of patients with its medicines.

More than 45 years ago, Amgen helped establish the biotechnology industry at its U.S. headquarters in Thousand Oaks, California, and it remains at the cutting edge of innovation, using technology and human genetic data to push beyond what is known today. Amgen is advancing a broad and deep pipeline and portfolio of medicines to treat cancer, inflammatory conditions, rare diseases, heart disease and obesity and obesity-related conditions.

Amgen has been consistently recognized for innovation and workplace culture, including honors from Fast Company and Forbes. Amgen is one of the 30 companies that comprise the Dow Jones Industrial Average®, and it is also part of the Nasdaq-100 Index®, which includes the largest and most innovative non-financial companies listed on the Nasdaq Stock Market based on market capitalization.

For more information, visit Amgen.com and follow Amgen on X, LinkedIn, Instagram, YouTube, Facebook, TikTok and Threads.

Amgen Forward-Looking Statements

This news release contains forward-looking statements that are based on the current expectations and beliefs of Amgen. All statements, other than statements of historical


AMGEN ANNOUNCES RETIREMENT OF DAVID M. REESE, EXECUTIVE VICE PRESIDENT AND CHIEF TECHNOLOGY OFFICER
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fact, are statements that could be deemed forward-looking statements, including any statements on the outcome, benefits and synergies of collaborations, or potential collaborations, with any other company (including BeOne Medicines Ltd.), the performance of Otezla® (apremilast), our acquisitions of ChemoCentryx, Inc., Dark Blue Therapeutics, Ltd. or Horizon Therapeutics plc (including the prospective performance and outlook of Horizon’s business, performance and opportunities, and any potential strategic benefits, synergies or opportunities expected as a result of such acquisition), as well as estimates of revenues, operating margins, capital expenditures, cash, other financial metrics, expected legal, arbitration, political, regulatory or clinical results or practices, customer and prescriber patterns or practices, reimbursement activities and outcomes, effects of pandemics or other widespread health problems on our business, outcomes, progress, and other such estimates and results. Forward-looking statements involve significant risks and uncertainties, including those discussed below and more fully described in the Securities and Exchange Commission reports filed by Amgen, including our most recent annual report on Form 10-K and any subsequent periodic reports on Form 10-Q and current reports on Form 8-K. Unless otherwise noted, Amgen is providing this information as of the date of this news release and does not undertake any obligation to update any forward-looking statements contained in this document as a result of new information, future events or otherwise.

 

No forward-looking statement can be guaranteed and actual results may differ materially from those we project. Our results may be affected by our ability to successfully market both new and existing products domestically and internationally, clinical and regulatory developments involving current and future products, sales growth of recently launched products, competition from other products including biosimilars, difficulties or delays in manufacturing our products and global economic conditions, including those resulting from geopolitical relations and government actions. In addition, sales of our products are affected by pricing pressure, political and public scrutiny and reimbursement policies imposed by third-party payers, including governments, private insurance plans and managed care providers and may be affected by regulatory, clinical and guideline developments and domestic and international trends toward managed care and healthcare cost containment. Furthermore, our research, testing, pricing, marketing and other operations are subject to extensive regulation by domestic and foreign government regulatory authorities. We or others could identify safety, side effects or manufacturing problems with our products, including our devices, after they are on the market. Our business may be impacted by government investigations, litigation and product liability claims. In addition, our business may be impacted by the adoption of new tax legislation or exposure to additional tax liabilities. Further, while we routinely obtain patents for our products and technology, the protection offered by our patents and patent applications may be challenged, invalidated or circumvented by our competitors, or we may fail to prevail in present and future intellectual property litigation. We perform a substantial amount of our commercial manufacturing activities at a few key facilities, including in Puerto Rico, and also depend on third parties for a portion of our manufacturing activities, and limits on supply may constrain sales of certain of our current products and product candidate development. An outbreak of disease or similar public health threat, and the public and governmental effort to mitigate against


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the spread of such disease, could have a significant adverse effect on the supply of materials for our manufacturing activities, the distribution of our products, the commercialization of our product candidates, and our clinical trial operations, and any such events may have a material adverse effect on our product development, product sales, business and results of operations. We rely on collaborations with third parties for the development of some of our product candidates and for the commercialization and sales of some of our commercial products. In addition, we compete with other companies with respect to many of our marketed products as well as for the discovery and development of new products. Discovery or identification of new product candidates or development of new indications for existing products cannot be guaranteed and movement from concept to product is uncertain; consequently, there can be no guarantee that any particular product candidate or development of a new indication for an existing product will be successful and become a commercial product. Further, some raw materials, medical devices and component parts for our products are supplied by sole third-party suppliers. Certain of our distributors, customers and payers have substantial purchasing leverage in their dealings with us. The discovery of significant problems with a product similar to one of our products that implicate an entire class of products could have a material adverse effect on sales of the affected products and on our business and results of operations. Our efforts to collaborate with or acquire other companies, products or technology, and to integrate the operations of companies or to support the products or technology we have acquired, may not be successful, and may result in unanticipated costs, delays or failures to realize the benefits of the transactions. A breakdown, cyberattack or information security breach of our information technology systems could compromise the confidentiality, integrity and availability of our systems and our data. Our stock price is volatile and may be affected by a number of events. Our business and operations may be negatively affected by the failure, or perceived failure, of achieving our sustainability objectives. The effects of global climate change and related natural disasters could negatively affect our business and operations. Global economic conditions may magnify certain risks that affect our business. Our business performance could affect or limit the ability of our Board of Directors to declare a dividend or our ability to pay a dividend or repurchase our common stock. We may not be able to access the capital and credit markets on terms that are favorable to us, or at all.

###

CONTACT: Amgen, Thousand Oaks

Elissa Snook, 609-251-1407 (media)

Casey Capparelli, 805-447-1746 (investors)

 


FAQ

What executive change did Amgen (AMGN) announce regarding David M. Reese?

Amgen announced that David M. Reese, M.D., will retire as executive vice president and Chief Technology Officer effective June 30, 2026. He will remain an executive vice president until that date and receive retirement benefits available under existing company plans and policies.

Who will oversee research, AI and data at Amgen (AMGN) after the restructuring?

James Bradner, M.D., will serve as executive vice president, Research and Development, Artificial Intelligence and Data. He brings experience at the intersection of biology and technology and will guide Amgen’s efforts to use emerging technologies in biomedical research and drug development.

Who becomes Chief Technology Officer at Amgen following David Reese’s retirement?

Sean Bruich will become senior vice president and Chief Technology Officer. He is described as a seasoned technology and data science leader who has advanced Amgen’s artificial intelligence and data capabilities and previously led global insights and AI organizations through major industry transitions.

How do these leadership changes support Amgen’s convergent innovation strategy?

The new structure is designed to deepen integration of biology, data science and advanced technologies such as artificial intelligence. Amgen states this alignment should help accelerate discovery and development of medicines and better connect how patients, providers and partners interact with the healthcare system.

What is Amgen’s definition of convergent innovation in this filing?

Amgen describes convergent innovation as bringing together biology, data science and advanced technologies such as artificial intelligence. The goal is to speed up new medicine discovery and development, and transform how patients, providers and partners engage with the broader healthcare ecosystem globally.

Filing Exhibits & Attachments

2 documents