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Apogee director’s funds exit stake at $135.11

(Very High)
(Neutral)
Form Type
4

Rhea-AI Filing Summary

Apogee Therapeutics, Inc. (APGE) director Nimish P. Shah reported multiple dispositions of equity interests on September 3, 2026, all made in connection with the acquisition of Apogee by AbbVie Inc. Venrock-affiliated funds and entities associated with Shah exchanged common stock, Non-Voting Common Stock, stock options and pre-funded warrants for cash based on $135.11 per share merger consideration, including options where the cash paid equaled $135.11 minus the option exercise price. The filing states that Shah and the relevant Venrock management entities disclaim beneficial ownership of the fund-held securities except for their indirect pecuniary interests, and that the reported fund and warrant positions and Non-Voting Common Stock holdings are reduced to zero following these transactions.

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Insider Shah Nimish P
Role Director
Type Security Shares Price Value
Disposition Non-Voting Common Stock F3, F4, F2 6,743,321 $135.11 $911.09M
Disposition Stock Option (Right to Buy) F6, F5, F7 47,758 -- --
Disposition Stock Option (Right to Buy) F6, F5, F7 10,370 -- --
Disposition Stock Option (Right to Buy) F6, F5, F7 14,461 -- --
Disposition Stock Option (Right to Buy) F6, F5, F7 7,657 -- --
Disposition Pre-Funded Warrants (Right to Buy) F8, F6, F9, F10 365,853 -- --
Disposition Common Stock F1, F2 1,750,000 $135.11 $236.44M
Holdings After Transaction: Non-Voting Common Stock — 0 contracts (Indirect, See footnote); Stock Option (Right to Buy) — 0 contracts (Direct); Pre-Funded Warrants (Right to Buy) — 0 contracts (Indirect, See footnote); Common Stock — 0 shares (Indirect, See footnote)
Footnotes (10)
  1. F1. The reported securities, which were disposed of in connection with the acquisition of the Issuer by AbbVie Inc. (the "Merger"), represent (i) 460,075 shares of the Issuer's common stock ("Common Stock") held by Venrock Healthcare Capital Partners III, L.P. ("VHCP III"), (ii) 46,025 shares held by VHCP Co-Investment Holdings III, LLC ("VHCP Co-III") and (iii) 1,243,900 shares held by Venrock Healthcare Capital Partners EG, L.P. ("VHCP EG").
  2. F2. VHCP Management III, LLC ("VHCPM III") is the sole general partner of VHCP III and the sole manager of VHCP Co-III. VHCP Management EG, LLC ("VHCPM EG") is the sole general partner of VHCP EG. Dr. Bong Koh and Nimish Shah are the voting members of VHCPM III and VHCPM EG. Dr. Koh, Mr. Shah, VHCPM III and VHCPM EG disclaim beneficial ownership over all shares held by VHCP III, VHCP Co-III, and VHCP EG, except to the extent of their respective indirect pecuniary interests therein.
  3. F3. The Non-Voting Common Stock was convertible at any time and had no expiration date.
  4. F4. The reported securities, which were disposed of in connection with the Merger, represent (i) 2,495,319 shares of Non-Voting Common Stock held directly by VHCP III, (ii) 249,522 shares of Non-Voting Common Stock held directly by VHCP Co-III and (iii) 3,998,480 shares of Non-Voting Common Stock held directly by VHCP EG.
  5. F5. The reported options were vested as of the date of the Merger or became fully vested in connection with the Merger.
  6. F6. Each reported option and warrant was disposed of in connection with the Merger in exchange for a cash payment equal to the excess of $135.11 (the per share merger consideration) over the exercise price of such option or warrant.
  7. F7. Under an agreement between the Reporting Person and Venrock Management, LLC (the "Management Company"), the Reporting Person is deemed to hold the reported option and the shares underlying the option for the sole benefit of the Management Company. The Reporting Person disclaims beneficial ownership of the reported shares except to the extent of his pecuniary interest therein.
  8. F8. The exercise price of each reported warrant is $0.00001 per share.
  9. F9. The reported warrants had no expiration date and were exercisable immediately upon grant.
  10. F10. The reported warrants are held directly by Venrock Opportunities Fund, L.P. ("VOF"). Venrock Opportunities Management, LLC ("VO Management") is the general partner of VOF. The Reporting Person is a voting member of VO Management and expressly disclaims beneficial ownership over all shares held by VOF except to the extent of his indirect pecuniary interests therein.
Common Stock disposed 1,750,000 shares Common stock held by VHCP III, VHCP Co-III and VHCP EG, disposed in AbbVie acquisition at $135.11 per share
Non-Voting Common Stock disposed 6,743,321 shares Non-Voting Common Stock held by VHCP III, VHCP Co-III and VHCP EG, disposed in merger at $135.11 per share
Per share merger consideration $135.11 per share Cash paid for each share, option or warrant in connection with AbbVie’s acquisition of Apogee
Pre-funded warrants disposed 365,853 warrants Pre-funded warrants on common stock held by Venrock Opportunities Fund, L.P., exchanged for cash in the merger
Pre-funded warrant exercise price $0.00001 per share Exercise price of the reported pre-funded warrants before being cashed out in the merger
Stock option exercise prices $17.00, $43.85, $41.66, $85.00 per share Exercise prices of four stock option grants over Apogee common stock disposed of for cash equal to $135.11 minus exercise price
Non-Voting Common Stock terms Convertible any time, no expiration Conversion features of Non-Voting Common Stock before disposition in the AbbVie acquisition
Non-Voting Common Stock financial
"The Non-Voting Common Stock was convertible at any time and had no expiration date."
A non-voting common stock is an ownership share in a company that gives holders the same economic rights as regular shares—such as claiming a portion of profits and benefiting from price gains—but does not give the holder the right to vote on corporate decisions. Think of it like owning a seat on a train that shares the ride’s benefits but not the ability to steer the engine; investors care because it affects their influence over management, potential control disputes, and sometimes the stock’s price or attractiveness.
pre-funded warrants financial
"The reported warrants are held directly by Venrock Opportunities Fund, L.P."
Pre-funded warrants are financial instruments that give investors the right to purchase a company's stock at a set price, but with most or all of the purchase price paid upfront. They function like a coupon or gift card for stock, allowing investors to buy shares later at a fixed price, which can be beneficial if they want to avoid future price increases. This makes them important for investors seeking flexibility and certainty in their investment plans.
per share merger consideration financial
"equal to the excess of $135.11 (the per share merger consideration) over the exercise price"
beneficial ownership regulatory
"disclaim beneficial ownership over all shares held by VHCP III, VHCP Co-III, and VHCP EG"
Beneficial ownership means the person or entity that actually enjoys the benefits of owning shares or other assets — such as receiving dividends, voting rights, or price gains — even if the legal title is held in another name. For investors it matters because knowing who truly controls and profits from a company reveals who can influence decisions, exposes potential conflicts of interest or hidden concentration of power, and affects transparency and risk in the stock.
pecuniary interests financial
"except to the extent of their respective indirect pecuniary interests therein"
indirect pecuniary interests financial
"except to the extent of his indirect pecuniary interests therein."

FAQ

What did APGE director Nimish P. Shah report in this Form 4?

He reported dispositions of Apogee equity on September 3, 2026, including common stock, Non-Voting Common Stock, options, and pre-funded warrants, all exchanged for cash in connection with AbbVie Inc.’s acquisition of Apogee at $135.11 per share merger consideration.

How were APGE stock options treated in this Form 4 filing?

Several batches of stock options over Apogee common stock were disposed of in connection with the merger. Each option was exchanged for a cash payment equal to $135.11 (the per share merger consideration) minus its stated exercise price, and the options were vested or became fully vested at the merger.

What is disclosed about the pre-funded warrants on APGE common stock?

Pre-funded warrants for 365,853 shares of Apogee common stock, held by Venrock Opportunities Fund, L.P., were disposed of in connection with the merger. The warrants had an exercise price of $0.00001 per share, were exercisable immediately upon grant, had no expiration date, and the reported position goes to zero.

Does Nimish P. Shah retain any reported APGE holdings after these transactions?

The filing reports zero shares or warrants remaining for the common stock, Non-Voting Common Stock, and pre-funded warrants referenced. Shah and the Venrock management entities disclaim beneficial ownership in the fund-held securities except for their indirect pecuniary interests.

Were the APGE transactions under a Rule 10b5-1 trading plan?

No. The Form 4’s Rule 10b5-1 checkbox is not checked, and the footnotes describe the transactions as disposed of in connection with the acquisition of Apogee by AbbVie Inc., with merger consideration of $135.11 per share.

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SEC Form 4
FORM 4UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number:3235-0287
Estimated average burden
hours per response:0.5
X
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
Shah Nimish P

(Last)(First)(Middle)
C/O APOGEE THERAPEUTICS, INC.
1 LETTERMAN DRIVE, BUILDING B

(Street)
SAN FRANCISCO CALIFORNIA 94129

(City)(State)(Zip)

UNITED STATES

(Country)
2. Issuer Name and Ticker or Trading Symbol
Apogee Therapeutics, Inc. [ APGE ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
XDirector10% Owner
Officer (give title below)Other (specify below)
2a. Foreign Trading Symbol
3. Date of Earliest Transaction (Month/Day/Year)
09/03/2026
6. Individual or Joint/Group Filing (Check Applicable Line)
XForm filed by One Reporting Person
Form filed by More than One Reporting Person
4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year)2A. Deemed Execution Date, if any (Month/Day/Year)3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeVAmount(A) or (D)Price
Common Stock09/03/2026D1,750,000(1)D$135.110ISee footnote(2)
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year)3A. Deemed Execution Date, if any (Month/Day/Year)4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year)7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Non-Voting Common Stock$009/03/2026D6,743,321 (3) (3)Common Stock6,743,321(4)$135.110ISee footnote(2)
Stock Option (Right to Buy)$1709/03/2026D47,758 (5)07/13/2033Common Stock47,758(6)0D(7)
Stock Option (Right to Buy)$43.8509/03/2026D10,370 (5)06/05/2034Common Stock10,370(6)0D(7)
Stock Option (Right to Buy)$41.6609/03/2026D14,461 (5)06/17/2035Common Stock14,461(6)0D(7)
Stock Option (Right to Buy)$8509/03/2026D7,657 (5)06/09/2036Common Stock7,657(6)0D(7)
Pre-Funded Warrants (Right to Buy)(8)09/03/2026D365,853 (9) (9)Common Stock365,853(6)0ISee footnote(10)
Explanation of Responses:
1. The reported securities, which were disposed of in connection with the acquisition of the Issuer by AbbVie Inc. (the "Merger"), represent (i) 460,075 shares of the Issuer's common stock ("Common Stock") held by Venrock Healthcare Capital Partners III, L.P. ("VHCP III"), (ii) 46,025 shares held by VHCP Co-Investment Holdings III, LLC ("VHCP Co-III") and (iii) 1,243,900 shares held by Venrock Healthcare Capital Partners EG, L.P. ("VHCP EG").
2. VHCP Management III, LLC ("VHCPM III") is the sole general partner of VHCP III and the sole manager of VHCP Co-III. VHCP Management EG, LLC ("VHCPM EG") is the sole general partner of VHCP EG. Dr. Bong Koh and Nimish Shah are the voting members of VHCPM III and VHCPM EG. Dr. Koh, Mr. Shah, VHCPM III and VHCPM EG disclaim beneficial ownership over all shares held by VHCP III, VHCP Co-III, and VHCP EG, except to the extent of their respective indirect pecuniary interests therein.
3. The Non-Voting Common Stock was convertible at any time and had no expiration date.
4. The reported securities, which were disposed of in connection with the Merger, represent (i) 2,495,319 shares of Non-Voting Common Stock held directly by VHCP III, (ii) 249,522 shares of Non-Voting Common Stock held directly by VHCP Co-III and (iii) 3,998,480 shares of Non-Voting Common Stock held directly by VHCP EG.
5. The reported options were vested as of the date of the Merger or became fully vested in connection with the Merger.
6. Each reported option and warrant was disposed of in connection with the Merger in exchange for a cash payment equal to the excess of $135.11 (the per share merger consideration) over the exercise price of such option or warrant.
7. Under an agreement between the Reporting Person and Venrock Management, LLC (the "Management Company"), the Reporting Person is deemed to hold the reported option and the shares underlying the option for the sole benefit of the Management Company. The Reporting Person disclaims beneficial ownership of the reported shares except to the extent of his pecuniary interest therein.
8. The exercise price of each reported warrant is $0.00001 per share.
9. The reported warrants had no expiration date and were exercisable immediately upon grant.
10. The reported warrants are held directly by Venrock Opportunities Fund, L.P. ("VOF"). Venrock Opportunities Management, LLC ("VO Management") is the general partner of VOF. The Reporting Person is a voting member of VO Management and expressly disclaims beneficial ownership over all shares held by VOF except to the extent of his indirect pecuniary interests therein.
/s/ Matthew Batters, as attorney-in-fact for Nimish Shah09/03/2026
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)