Welcome to our dedicated page for Apellis Pharmace SEC filings (Ticker: APLS), a comprehensive resource for investors and traders seeking official regulatory documents including 10-K annual reports, 10-Q quarterly earnings, 8-K material events, and insider trading forms.
The Apellis Pharmaceuticals, Inc. (APLS) SEC filings page on Stock Titan provides access to the company’s official disclosures filed with the U.S. Securities and Exchange Commission. As a commercial-stage biopharmaceutical issuer listed on the Nasdaq Global Select Market, Apellis uses filings such as Forms 10-K, 10-Q, 8-K, and others to report on its business, financial condition, risk factors, and material events related to its complement-based therapies SYFOVRE and EMPAVELI/Aspaveli.
In these filings, investors can review detailed information on revenue from SYFOVRE and EMPAVELI, research and development spending for ophthalmology and rare disease programs, and the status of key clinical trials such as GALE and VALIANT. Risk factor and management discussion sections typically describe the scientific and regulatory considerations associated with targeting C3 in geographic atrophy, C3 glomerulopathy, primary IC-MPGN, and paroxysmal nocturnal hemoglobinuria.
Current reports on Form 8-K, such as the Royalty Buy-Down Agreement with Swedish Orphan Biovitrum AB (Sobi), document material definitive agreements that affect Apellis’ economics, including ex-U.S. royalty structures for Aspaveli and related financing consents. These filings help clarify how collaborations and capital arrangements support the company’s commercialization and pipeline strategy.
On Stock Titan, Apellis filings are updated in near real time as they are posted to EDGAR. AI-powered summaries highlight key points from lengthy documents, helping readers quickly understand topics like royalty arrangements, cash runway, product revenue trends, and major clinical or regulatory milestones. Users can also review Forms 4 and other insider transaction reports to monitor trading activity by Apellis directors and executives, alongside proxy and governance disclosures that describe compensation and board oversight. This page is a central resource for analyzing the regulatory record behind APLS stock.
Apellis Pharmaceuticals (APLS) Form 144: proposed sale of 20,000 common shares. The notice reports an intended sale of 20,000 shares through Morgan Stanley Smith Barney on 09/10/2025 on NASDAQ with an aggregate market value of $523,436. The filing shows the seller previously acquired the shares as performance stock units and exercised options across four acquisition dates: 09/18/2018, 01/27/2021, 01/28/2022 and 09/08/2025. The filer sold 15,000 shares in the past three months across three trades on 06/16/2025, 07/16/2025 and 08/18/2025 for gross proceeds of $93,850, $97,750 and $139,000 respectively. The notice includes the standard representation that the seller is unaware of any undisclosed material adverse information about the issuer.
Apellis Pharmaceuticals insider Timothy E. Sullivan, the company's Chief Financial Officer, executed option exercises and share sales under a 10b5-1 plan on 09/08/2025. He exercised options to purchase 15,000 shares at an exercise price of $10.03, resulting in 15,000 newly acquired shares and increasing his directly held shares to 242,903. Concurrently, he sold 32,729 shares at a weighted average price of $27.86 and an additional 10,000 shares at $27.83, with sale prices ranging from $27.67 to $27.98. After these transactions, the reporting person directly owned 110,936 shares and indirectly held 60,396 shares through The Timothy E Sullivan Irrevocable Trust of 2023, which he disclaims beneficial ownership of except for his pecuniary interest. The transactions were reported on Form 4 and signed by an attorney-in-fact on 09/10/2025.
Apellis Pharmaceuticals (APLS) insider filing reports a proposed sale under Rule 144 by Timothy Sullivan. The notice lists a planned block of 10,000 shares to be sold through UBS with an aggregate market value of $280,000, and indicates a recent sale on 09/08/2025 of 32,729 shares generating gross proceeds of $911,829. The company has 126,289,910 shares outstanding, so the disclosed transactions represent a small fraction of total equity. The shares being offered were acquired via option exercises on 04/18/2024 in four lots totaling 10,000 shares, with cash payment recorded on the original acquisition dates.
Apellis Pharmaceuticals reported a Form 144 notice for a proposed sale of 32,729 shares of common stock through Fidelity Brokerage Services LLC with an aggregate market value of $911,829.94. The filing lists the approximate date of sale as 09/08/2025 and identifies the shares outstanding as 126,289,910. The notice discloses recent acquisitions of the shares: multiple restricted stock vesting events in January 2025 totaling 17,729 shares and an option-related item of 15,000 shares listed with a 09/08/2025 payment date described as Cash.
The filer certifies no undisclosed material adverse information and provides no reportable sales in the past three months. The form presents the broker, quantities, acquisition dates, nature of acquisition, and payment type but does not include the seller’s identity or reasons for sale.
Apellis Pharmaceuticals insider James G. Chopas, listed as VP/Chief Accounting Officer, reported a sale of 548 shares of Apellis common stock on 09/02/2025 at a price of $28.077 per share. The filing states that the shares were sold to cover tax withholding on Restricted Stock Units released on August 29, 2025. After the transaction, Chopas beneficially owns 53,657 shares, held directly. The Form 4 was signed by an attorney-in-fact on 09/03/2025. No other derivative transactions or additional material information are reported.
Apellis Pharmaceuticals insider Kelley Boucher received equity awards on 09/02/2025. The filing shows a grant of 30,476 restricted stock units that vest 25% annually over four years, subject to continued service or termination provisions. Following the grant, Ms. Boucher beneficially owns 97,658 shares of common stock.
The filing also reports a stock option award for 45,766 shares with an exercise price of $28.17, exercisable beginning 09/02/2026 under a four-year vesting schedule and expiring 09/02/2035. The Form 4 was signed by an attorney-in-fact on 09/03/2025.
Apellis Pharmaceuticals, Inc. (APLS) Form 144 reports a proposed sale of 548 shares of common stock through Fidelity Brokerage Services LLC with an aggregate market value of $15,386.20. The filing shows approximately 126,289,910 shares outstanding and lists the approximate sale date as 09/02/2025 on the NASDAQ. The shares were acquired by restricted stock vesting on 08/29/2025 and the stated nature of payment is compensation. The filer reports no securities sold in the past three months and includes the standard Rule 144 attestation regarding material nonpublic information.
Apellis Pharmaceuticals insider Leslie Meltzer received equity awards on August 26, 2025. The filing shows a grant of 61,804 restricted stock units (RSUs) that vest 25% annually over four years subject to continued service, and a stock option to purchase 92,592 shares with an exercise price of $16.20 that vests over four years (25% after one year, then monthly thereafter) and expires August 26, 2035. After the transactions, Meltzer beneficially owns 61,804 shares from the RSUs and 92,592 underlying the option, reported as direct ownership. The form was signed by an attorney-in-fact on behalf of Meltzer on September 2, 2025.
Apellis Pharmaceuticals filed an initial Form 3 reporting that Leslie Meltzer, the company's Chief Research and Development Officer and an officer/director, submitted a statement of beneficial ownership tied to an event dated 08/26/2025. The filing discloses that no securities are beneficially owned by the reporting person. The form was signed on behalf of Ms. Meltzer by an attorney-in-fact, David Watson, with a signature date of 09/02/2025. The filing includes the reporting person's Waltham, MA business address but contains no holdings, derivative positions, or other ownership details.
Cedric Francois, Chief Executive Officer and Director of Apellis Pharmaceuticals (APLS), reported insider sales on August 27–28, 2025. The Form 4 shows sales of 175,037 shares on 08/27/2025 at a weighted-average price of $28.19 and 49,963 shares on 08/28/2025 at a weighted-average price of $28.39, totaling 225,000 shares sold. The filing reports post-transaction beneficial ownership figures of 357,909 shares (after the 08/27 sale) and 307,946 shares (after the 08/28 sale). The report also discloses multiple indirect holdings held in trusts: 472,065 shares, 300,000 shares and 234,411 shares, with trustees named in the footnotes. Footnotes clarify weighted-average price ranges and the reporting persons limited beneficial interest in trust-held shares.