Nasdaq starts delisting of Applied Therapeutics (NASDAQ: APLT) stock

Rhea-AI Filing Summary

Applied Therapeutics, Inc. is having its common stock removed from listing and registration on the Nasdaq Stock Market, as reflected in a Form 25 filed under Section 12(b) of the Exchange Act. Nasdaq states it has complied with its own rules and the SEC’s requirements for striking this class of securities from listing or effecting a voluntary withdrawal.

Positive

• None.

Negative

• Nasdaq delisting of common stock: Applied Therapeutics’ common stock is being removed from listing and registration on the Nasdaq Stock Market under Section 12(b), a materially negative change that can reduce liquidity and limit access to some institutional investors.

Insights

Equity markets and listing standards analyst

Nasdaq is removing Applied Therapeutics’ common stock from its exchange, a materially adverse listing change.

The document shows that Applied Therapeutics’ common stock is being removed from listing and registration on the Nasdaq Stock Market via a Form 25 under Section 12(b). The filing cites the applicable SEC rules governing striking a class of securities or voluntary withdrawal.

Removal from a major exchange typically reduces trading liquidity and can narrow the investor base, as some institutions require an exchange listing. It may also affect future access to equity capital that relies on exchange trading. Actual impact will depend on alternative trading venues and subsequent corporate actions.

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SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 25

NOTIFICATION OF REMOVAL FROM LISTING AND/OR REGISTRATION
UNDER SECTION 12(b) OF THE SECURITIES EXCHANGE ACT OF 1934.

Commission File Number

001-38898

Issuer:	Applied Therapeutics, Inc.
Exchange:	Nasdaq Stock Market LLC

(Exact name of Issuer as specified in its charter, and name of Exchange where security is listed and/or registered)

Address:	340 Madison Avenue
	New York	NEW YORK	10173
Telephone number:					2,122,209,226

(Address, including zip code, and telephone number, including area code, of Issuer's principal executive offices)

Common Stock

(Description of class of securities)

Please place an X in the box to designate the rule provision relied upon to strike the class of securities from listing and registration:

17 CFR 240.12d2-2(a)(1)

17 CFR 240.12d2-2(a)(2)

17 CFR 240.12d2-2(a)(3)

17 CFR 240.12d2-2(a)(4)

Pursuant to 17 CFR 240.12d2-2(b), the Exchange has complied with its rules to strike the class of securities from listing and/or withdraw registration on the Exchange. ¹

Pursuant to 17 CFR 240.12d2-2(c), the Issuer has complied with its rules of the Exchange and the requirements of 17 CFR 240.12d-2(c) governing the voluntary withdrawal of the class of securities from listing and registration on the Exchange.

Pursuant to the requirements fo the Securities Exchange Act of 1934, Nasdaq Stock Market LLC certifies that it has reasonable grounds to believe that it meets all of the requirements for filing the Form 25 and has caused this notification to be signed on its behalf by the undersigned duly authorized person.

2026-02-03	By	Tara Petta		Director
Date		Name		Title

¹ Form 25 and attached Notice will be considered compliance with the provisions of 17 CFR 240.19d-1 as applicable. See General Instructions.

Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What does Nasdaq’s Form 25 mean for Applied Therapeutics (APLT)?

It means Applied Therapeutics’ common stock is being removed from listing and registration on the Nasdaq Stock Market under Section 12(b). This generally shifts trading to less prominent venues and can reduce liquidity and institutional investor participation.

Which securities of Applied Therapeutics (APLT) are affected by this delisting?

The Form 25 covers Applied Therapeutics’ common stock, identified as the affected class of securities. The notification states that this class is being struck from listing and registration on the Nasdaq Stock Market in accordance with applicable SEC and exchange rules.

Is the Applied Therapeutics (APLT) Nasdaq delisting voluntary or exchange-driven?

The document references both rule provisions for exchange-initiated removal and for issuer-complied voluntary withdrawal. However, it only clearly confirms that the common stock is being removed from Nasdaq listing and registration, without specifying the underlying reason in the provided excerpt.

What regulatory framework governs the Applied Therapeutics (APLT) delisting?

The process is governed by Section 12(b) of the Securities Exchange Act and 17 CFR 240.12d2-2. The Form 25 states that Nasdaq has complied with its rules and the SEC requirements for striking or withdrawing the common stock from listing and registration.

Who signed the Nasdaq delisting notice for Applied Therapeutics (APLT)?

The notification is signed on behalf of Nasdaq Stock Market LLC by Tara Petta, listed as a Director. The signature section also certifies that Nasdaq has reasonable grounds to believe it meets all requirements for filing the Form 25.

Where is Applied Therapeutics (APLT) headquartered according to this document?

Applied Therapeutics’ principal executive offices are listed at 340 Madison Avenue, New York, New York 10173, with a New York telephone number. This address information appears as part of the issuer details in the Form 25 notification.