[Form 4] ARVINAS, INC. Insider Trading Activity

Rhea-AI Filing Summary

Arvinas (ARVN) insider update: Chief Accounting Officer David K. Loomis reported a sale of 230 shares of common stock on 11/07/2025 at $9.89 per share. The filing states the sale was made automatically by the company to cover tax withholding tied to the vesting and settlement of 25% of RSUs granted on December 13, 2022.

Following the transaction, Loomis beneficially owns 31,697 shares directly. This total includes 1,239 shares previously purchased under the company’s 2018 Employee Stock Purchase Plan.

Insights

Equity compensation & insider transactions analyst

Administrative tax sale; minimal investment impact.

The reported Form 4 shows a small sale of 230 shares at $9.89 on 11/07/2025. The note clarifies the transaction was an automatic sale by the issuer to satisfy tax withholding from the vesting of 25% of RSUs granted on December 13, 2022.

Such tax-withholding sales are common in equity compensation and do not reflect discretionary trading. After the transaction, the officer directly holds 31,697 shares, including 1,239 acquired via the 2018 ESPP.

Given the small size and administrative nature, this filing is typically neutral for valuation and liquidity considerations.

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Loomis David K

(Last) (First) (Middle)

C/O ARVINAS, INC.

5 SCIENCE PARK, 395 WINCHESTER AVE.

(Street)

NEW HAVEN CT 06511

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
ARVINAS, INC. [ ARVN ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director		10% Owner
X	Officer (give title below)		Other (specify below)
	Chief Accounting Officer

3. Date of Earliest Transaction (Month/Day/Year)
11/07/2025

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	11/07/2025		S		230(1)	D	$9.89	31,697(2)	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

1. This sale was made automatically by the Issuer to cover tax withholding obligations in connection with the vesting and settlement of 25% of the reporting person's restricted stock units (RSUs) granted on December 13, 2022.

2. Includes an aggregate of 1,239 shares of common stock of the issuer previously purchased under and in accordance with the 2018 Employee Stock Purchase Plan of the issuer in transactions exempt under Rule 16b-3.

Remarks:

	/s/ Christina Bailey, as attorney-in-fact for David K. Loomis	11/07/2025
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What did Arvinas (ARVN) disclose in this Form 4?

A sale of 230 shares of common stock on 11/07/2025 at $9.89 per share by the Chief Accounting Officer.

Why were the ARVN shares sold in this filing?

The filing states the sale was made automatically by the issuer to cover tax withholding from RSU vesting.

Which equity grant triggered the tax withholding sale at Arvinas?

The sale relates to the vesting and settlement of 25% of RSUs granted on December 13, 2022.

How many ARVN shares does the reporting person own after the transaction?

The officer beneficially owns 31,697 shares directly after the reported transaction.

Does the ownership total include ESPP shares for ARVN?

Yes. It includes 1,239 shares previously purchased under the 2018 Employee Stock Purchase Plan.