[424B2] BARCLAYS BANK PLC Prospectus Supplement

Rhea-AI Filing Summary

Barclays Bank PLC filed a preliminary 424B2 pricing supplement for unsecured, unsubordinated notes linked to an equally weighted basket of eight stocks: CEG, EQIX, ETN, FCX, NEE, PWR, VRT and VST (each 12.5%). The notes feature an Automatic Call: if the Basket Level on the Review Date is at or above the Initial Basket Level, holders receive the Call Price of $1,160 per $1,000 note (a 16.00% premium) on the Call Settlement Date.

If not called, the maturity payoff is: $1,000 plus the Basket Return times the Upside Leverage Factor of 1.25 when the Final Basket Level exceeds the Initial. Capital is protected down to a 15.00% Buffer (Buffer Value 85). Below the Buffer, losses are leveraged by a Downside Leverage Factor of 1.17647. Key dates: Review Date October 30, 2026; Final Valuation Date October 18, 2027; Maturity October 21, 2027.

Per-note economics: Initial Issue Price $1,000; Agent’s commission 1.50%; issuer proceeds 98.50%. The notes will not be listed on any U.S. exchange and are subject to U.K. Bail-in Power. Payments depend on Barclays Bank PLC’s credit and any exercise of bail-in.

The information in this preliminary pricing supplement is not complete and may be changed. This preliminary pricing supplement and the accompanying prospectus and prospectus supplement do not constitute an offer to sell the Notes and we are not soliciting an offer to buy the Notes in any state where the offer or sale is not permitted.

Subject to Completion. Dated October 16, 2025

Pricing Supplement dated October    , 2025 (To the Prospectus dated May 15, 2025 and the Prospectus Supplement dated May 15, 2025) Filed Pursuant to Rule 424(b)(2) Registration No. 333-287303

  $ Autocallable Buffered Return Enhanced Notes Due October 21, 2027
Linked to an Equally Weighted Basket of Eight Equity Securities Global Medium-Term Notes, Series A

General

· Unlike ordinary debt securities, the Notes do not pay interest and do not guarantee the return of the full principal amount at maturity. Instead, as described below, the Notes will be automatically called for a call premium if the Basket Level on the Review Date is greater than or equal to the Initial Basket Level. If the Notes are not automatically called, the Notes offer leveraged exposure to potential appreciation of the Basket from the Initial Basket Level to the Final Basket Level. Investors should be willing to forgo dividend payments and, if the Notes are not automatically called and the Final Basket Level is less than the Buffer Value, be willing to lose some or all of their investment at maturity.

· Unsecured and unsubordinated obligations of Barclays Bank PLC

· Minimum denominations of $10,000 and integral multiples of $1,000 in excess thereof

· The Notes are expected to price on or about October 16, 2025 (the “Pricing Date”) and are expected to issue on or about October 21, 2025 (the “Issue Date”). With respect to each Basket Component, the Initial Component Value is the Closing Price of that Basket Component on October 15, 2025 and is not the Closing Price of that Basket Component on the Pricing Date.

Key Terms*	Terms used in this pricing supplement, but not defined herein, shall have the meanings ascribed to them in the prospectus supplement.
Issuer:	Barclays Bank PLC
Basket:	An equally weighted basket (the “Basket”) consisting of the common stock of Constellation Energy Corporation (the “CEG Basket Component”), the common stock of Equinix, Inc. (the “EQIX Basket Component”), the ordinary shares of Eaton Corporation plc (the “ETN Basket Component”), the common stock of Freeport-McMoRan Inc. (the “FCX Basket Component”), the common stock of NextEra Energy, Inc. (the “NEE Basket Component”), the common stock of Quanta Services, Inc. (the “PWR Basket Component”), the Class A common stock of Vertiv Holdings Co (the “VRT Basket Component”) and the common stock of Vistra Corp. (the “VST Basket Component”) (each, a “Basket Component” and together, the “Basket Components”), as set forth in the following table:

	Basket Component	Bloomberg Ticker Symbol	Weighting	Initial Component Value*
	CEG Basket Component	CEG<Equity>	12.50%	$403.95
	EQIX Basket Component	EQIX<Equity>	12.50%	$822.24
	ETN Basket Component	ETN<Equity>	12.50%	$381.72
	FCX Basket Component	FCX<Equity>	12.50%	$41.71
	NEE Basket Component	NEE<Equity>	12.50%	$85.79
	PWR Basket Component	PWR<Equity>	12.50%	$436.93
	VRT Basket Component	VRT<Equity>	12.50%	$180.51
	VST Basket Component	VST<Equity>	12.50%	$210.85

	* With respect to each Basket Component, the Closing Price of that Basket Component on October 15, 2025. The Initial Component Value for each Basket Component is not the Closing Price of that Basket Component on the Pricing Date.
Automatic Call Feature:	If the Basket Level on the Review Date is greater than or equal to the Initial Basket Level, the Notes will be automatically called for a cash payment on the Call Settlement Date per $1,000 principal amount Note equal to the Call Price. No further amounts will be owed to you under the Notes.
Call Price:	$1,160.00 per $1,000 principal amount Note, representing a call premium of 16.00%. If the Notes are automatically called, the return on the Notes will not exceed the Call Price, and you will not participate in any appreciation in the value of the Basket, which may be significant.
Payment at Maturity:	If the Notes are not automatically called and the Final Basket Level is greater than the Initial Basket Level, you will receive a cash payment on the Maturity Date per $1,000 principal amount Note that will provide a return equal to the Basket Return multiplied by the Upside Leverage Factor, calculated as follows: $1,000 + ($1,000 × Basket Return × Upside Leverage Factor) If the Notes are not automatically called and the Final Basket Level is less than or equal to the Initial Basket Level but greater than or equal to the Buffer Value, you will receive a cash payment on the Maturity Date of $1,000 per $1,000 principal amount Note. If the Notes are not automatically called and the Final Basket Level is less than the Buffer Value, you will lose 1.17647% of the principal amount of your Notes for every 1% that the Final Basket Level is less than the Initial Basket Level. Under these circumstances, you will receive a cash payment on the Maturity Date per $1,000 principal amount Note calculated as follows: $1,000 + [$1,000 × (Basket Return + Buffer Percentage) × Downside Leverage Factor] If the Notes are not automatically called and the Final Basket Level is less than the Buffer Value, the Notes will be exposed on a leveraged basis to the decline in the value of the Basket below the Buffer Value and you will lose some or all of your investment at maturity. Any payment on the Notes, including any repayment of principal, is not guaranteed by any third party and is subject to (a) the creditworthiness of Barclays Bank PLC and (b) the risk of exercise of any U.K. Bail-in Power (as described on page PS- 4 of this pricing supplement) by the relevant U.K. resolution authority. See “Selected Risk Considerations” and “Consent to U.K. Bail-in Power” in this pricing supplement and “Risk Factors” in the accompanying prospectus supplement.
U.K. Bail-in Power Acknowledgment:	Notwithstanding and to the exclusion of any other term of the Notes or any other agreements, arrangements or understandings between Barclays Bank PLC and any holder or beneficial owner of the Notes (or the trustee on behalf of the holders of the Notes), by acquiring the Notes, each holder or beneficial owner of the Notes acknowledges, accepts, agrees to be bound by and consents to the exercise of, any U.K. Bail-in Power by the relevant U.K. resolution authority. See “Consent to U.K. Bail-in Power” on page PS-4 of this pricing supplement.

(Key Terms continued on the next page)

	Initial Issue Price1,2	Price to Public	Agent’s Commission2	Proceeds to Barclays Bank PLC
Per Note	$1,000	100%	1.50%	98.50%
Total	$●	$●	$●	$●

¹ Our estimated value of the Notes on the Pricing Date, based on our internal pricing models, is expected to be between $864.00 and $944.00 per $1,000 principal amount Note. The estimated value is expected to be less than the initial issue price of the Notes. See “Additional Information Regarding Our Estimated Value of the Notes” on page PS-23 of this pricing supplement.

² J.P. Morgan Securities LLC and JPMorgan Chase Bank, N.A. will act as placement agents for the Notes. The placement agents will forgo fees for sales to fiduciary accounts. The total fees represent the amount that the placement agents receive from sales to accounts other than such fiduciary accounts. The placement agents will receive a fee from the Issuer or one of its affiliates that will not exceed $15.00 per $1,000 principal amount Note.

Investing in the Notes involves a number of risks. See “Risk Factors” beginning on page S-9 of the prospectus supplement and “Selected Risk Considerations” beginning on page PS-9 of this pricing supplement.

The Notes will not be listed on any U.S. securities exchange or quotation system. Neither the U.S. Securities and Exchange Commission (the “SEC”) nor any state securities commission has approved or disapproved of these Notes or determined that this pricing supplement is truthful or complete. Any representation to the contrary is a criminal offense.

The Notes constitute our unsecured and unsubordinated obligations. The Notes are not deposit liabilities of Barclays Bank PLC and are not covered by the U.K. Financial Services Compensation Scheme or insured by the U.S. Federal Deposit Insurance Corporation or any other governmental agency or deposit insurance agency of the United States, the United Kingdom or any other jurisdiction.

JPMorgan
Placement Agent

(Key Terms continued from previous page)

Upside Leverage Factor:	1.25. The Upside Leverage Factor applies only if the Notes are not automatically called.
Basket Return:	Final Basket Level – Initial Basket Level Initial Basket Level
Initial Basket Level:	100
Buffer Value:	85, which is 85.00% of the Initial Basket Level
Buffer Percentage:	15.00%
Downside Leverage Factor:	1.17647
Final Basket Level:	The Basket Level on the Final Valuation Date
Basket Level:	On any relevant day, the Basket Level will be calculated as follows: 100 × [1 + (the sum of, for each Basket Component, its Basket Component Return on that day times its Weighting)]
Basket Component Return:	With respect to each Basket Component, on any relevant day, an amount calculated as follows: Closing Price on that day – Initial Component Value Initial Component Value
Closing Price:	Closing Price has the meaning set forth under “Reference Assets—Equity Securities—Special Calculation Provisions” in the prospectus supplement.
Review Date†:	October 30, 2026
Call Settlement Date†:	November 4, 2026
Final Valuation Date†:	October 18, 2027
Maturity Date†:	October 21, 2027
Calculation Agent:	Barclays Bank PLC
CUSIP/ISIN:	06746EHC2 / US06746EHC21

* The Basket Components and the terms of the Notes are subject to adjustment by the Calculation Agent and the Maturity Date may be accelerated, in each case under certain circumstances as set forth in the accompanying prospectus supplement. See “Selected Risk Considerations—Risks Relating to the Basket Components” below.

^† Subject to postponement in certain circumstances, as described under “Reference Assets—Equity Securities—Market Disruption Events for Securities with an Equity Security as a Reference Asset,” “Reference Assets—Baskets—Scheduled Trading Days and Market Disruption Events for Securities Linked to a Basket of Equity Securities, Exchange-Traded Funds, Equity Indices and/or Equity Futures Indices” and “Terms of the Notes—Payment Dates” in the accompanying prospectus supplement

PS-2 

Additional Terms Specific to the Notes

You should read this pricing supplement together with the prospectus dated May 15, 2025, as supplemented by the prospectus supplement dated May 15, 2025 relating to our Global Medium-Term Notes, Series A, of which these Notes are a part. This pricing supplement, together with the documents listed below, contains the terms of the Notes and supersedes all prior or contemporaneous oral statements as well as any other written materials including preliminary or indicative pricing terms, correspondence, trade ideas, structures for implementation, sample structures, brochures or other educational materials of ours. You should carefully consider, among other things, the matters set forth under “Risk Factors” in the prospectus supplement and “Selected Risk Considerations” in this pricing supplement, as the Notes involve risks not associated with conventional debt securities. We urge you to consult your investment, legal, tax, accounting and other advisors before you invest in the Notes.

You may access these documents on the SEC website at www.sec.gov as follows (or if such address has changed, by reviewing our filings for the relevant date on the SEC website):

· Prospectus dated May 15, 2025:
http://www.sec.gov/Archives/edgar/data/312070/000119312525120720/d925982d424b2.htm

· Prospectus supplement dated May 15, 2025:
http://www.sec.gov/Archives/edgar/data/312070/000095010325006051/dp228678_424b2-prosupp.htm

Our SEC file number is 1-10257. As used in this pricing supplement, “we,” “us” and “our” refer to Barclays Bank PLC.

PS-3 

Consent to U.K. Bail-in Power

Notwithstanding and to the exclusion of any other term of the Notes or any other agreements, arrangements or understandings between us and any holder or beneficial owner of the Notes (or the trustee on behalf of the holders of the Notes), by acquiring the Notes, each holder or beneficial owner of the Notes acknowledges, accepts, agrees to be bound by and consents to the exercise of, any U.K. Bail-in Power by the relevant U.K. resolution authority.

Under the U.K. Banking Act 2009, as amended, the relevant U.K. resolution authority may exercise a U.K. Bail-in Power in circumstances in which the relevant U.K. resolution authority is satisfied that the resolution conditions are met. These conditions include that a U.K. bank or investment firm is failing or is likely to fail to satisfy the Financial Services and Markets Act 2000 (the “FSMA”) threshold conditions for authorization to carry on certain regulated activities (within the meaning of section 55B FSMA) or, in the case of a U.K. banking group company that is a European Economic Area (“EEA”) or third country institution or investment firm, that the relevant EEA or third country relevant authority is satisfied that the resolution conditions are met in respect of that entity.

The U.K. Bail-in Power includes any write-down, conversion, transfer, modification and/or suspension power, which allows for (i) the reduction or cancellation of all, or a portion, of the principal amount of, or interest on, or any other amounts payable on, the Notes; (ii) the conversion of all, or a portion, of the principal amount of, or interest on, or any other amounts payable on, the Notes into shares or other securities or other obligations of Barclays Bank PLC or another person (and the issue to, or conferral on, the holder or beneficial owner of the Notes of such shares, securities or obligations); (iii) the cancellation of the Notes and/or (iv) the amendment or alteration of the maturity of the Notes, or the amendment of the amount of interest or any other amounts due on the Notes, or the dates on which interest or any other amounts become payable, including by suspending payment for a temporary period; which U.K. Bail-in Power may be exercised by means of a variation of the terms of the Notes solely to give effect to the exercise by the relevant U.K. resolution authority of such U.K. Bail-in Power. Each holder and beneficial owner of the Notes further acknowledges and agrees that the rights of the holders or beneficial owners of the Notes are subject to, and will be varied, if necessary, solely to give effect to, the exercise of any U.K. Bail-in Power by the relevant U.K. resolution authority. For the avoidance of doubt, this consent and acknowledgment is not a waiver of any rights holders or beneficial owners of the Notes may have at law if and to the extent that any U.K. Bail-in Power is exercised by the relevant U.K. resolution authority in breach of laws applicable in England.

For more information, please see “Selected Risk Considerations—Risks Relating to the Issuer—You May Lose Some or All of Your Investment If Any U.K. Bail-in Power Is Exercised by the Relevant U.K. Resolution Authority” in this pricing supplement as well as “U.K. Bail-in Power,” “Risk Factors—Risks Relating to the Securities Generally—Regulatory action in the event a bank or investment firm in the Group is failing or likely to fail, including the exercise by the relevant U.K. resolution authority of a variety of statutory resolution powers, could materially adversely affect the value of any securities” and “Risk Factors—Risks Relating to the Securities Generally—Under the terms of the securities, you have agreed to be bound by the exercise of any U.K. Bail-in Power by the relevant U.K. resolution authority” in the accompanying prospectus supplement.

PS-4 

What Is the Payment Upon an Automatic Call?

If the Basket Level on the Review Date is greater than or equal to the Initial Basket Level, the Notes will be automatically called for a cash payment on the Call Settlement Date of the Call Price of $1,160.00 per $1,000 principal amount Note. No further amounts will be owed to you under the Notes. If your Notes are automatically called, the return on your Notes will not exceed the Call Price, regardless of any appreciation in the value of the Basket, which may be significant.

If the Notes Are Not Automatically Called, What Is the Total Return on the Notes at Maturity, Assuming a Range of Performances for the Basket?

The following table and examples illustrate the hypothetical payment at maturity and the hypothetical total return on the Notes if the Notes are not automatically called. The “total return” as used in this pricing supplement is the number, expressed as a percentage, that results from comparing the payment at maturity per $1,000 principal amount Note to $1,000. The table and examples set forth below reflect the Initial Basket Level of 100.00 and assume the Final Basket Levels set forth below. The actual Final Basket Level will be the Basket Level on the Final Valuation Date. For historical performance of the Basket and historical Closing Prices of the Basket Components, see the historical information set forth under the sections titled “Information about the Basket” and “Information about the Basket Components” below. Each hypothetical payment at maturity or total return set forth below is for illustrative purposes only and may not be the actual payment at maturity or total return applicable to a purchaser of the Notes. The numbers appearing in the following table and examples have been rounded for ease of analysis. The table and examples below do not take into account any tax consequences from investing in the Notes.

Final Basket Level	Basket Return	Payment at Maturity	Total Return on Notes
200.00	100.00%	$2,250.00	125.000%
190.00	90.00%	$2,125.00	112.500%
180.00	80.00%	$2,000.00	100.000%
170.00	70.00%	$1,875.00	87.500%
160.00	60.00%	$1,750.00	75.000%
150.00	50.00%	$1,625.00	62.500%
140.00	40.00%	$1,500.00	50.000%
130.00	30.00%	$1,375.00	37.500%
120.00	20.00%	$1,250.00	25.000%
115.00	15.00%	$1,187.50	18.750%
110.00	10.00%	$1,125.00	12.500%
105.00	5.00%	$1,062.50	6.250%
100.00	0.00%	$1,000.00	0.000%
95.00	-5.00%	$1,000.00	0.000%
90.00	-10.00%	$1,000.00	0.000%
85.00	-15.00%	$1,000.00	0.000%
80.00	-20.00%	$941.18	-5.882%
70.00	-30.00%	$823.53	-17.647%
60.00	-40.00%	$705.88	-29.412%
50.00	-50.00%	$588.24	-41.176%
40.00	-60.00%	$470.59	-52.941%
30.00	-70.00%	$352.94	-64.706%
20.00	-80.00%	$235.29	-76.471%
10.00	-90.00%	$117.65	-88.235%
0.00	-100.00%	$0.00	-100.000%

PS-5 

Hypothetical Examples of Amount Payable at Maturity

The following examples illustrate how the payment at maturity and total return in different hypothetical scenarios are calculated.

Example 1: The Notes are not automatically called and the value of the Basket increases from the Initial Basket Level of 100.00 to a Final Basket Level of 110.00, resulting in a Basket Return of 10.00%.

Because the Notes are not automatically called and the Final Basket Level is greater than the Initial Basket Level and the Basket Return is 10.00%, the investor receives a payment at maturity of $1,125.00 per $1,000 principal amount Note, calculated as follows:

$1,000 + ($1,000 × Basket Return × Upside Leverage Factor)

$1,000 + ($1,000 × 10.00% × 1.25) = $1,125.00

The total return on the Notes is 12.50%.

Example 2: The Notes are not automatically called and the value of the Basket decreases from the Initial Basket Level of 100.00 to a Final Basket Level of 90.00, resulting in a Basket Return of -10.00%.

Because the Notes are not automatically called and the Final Basket Level is less than or equal to the Initial Basket Level but is greater than or equal to the Buffer Value, the investor receives a payment at maturity of $1,000.00 per $1,000 principal amount Note.

The total return on the Notes is 0.00%.

Example 3: The Notes are not automatically called and the value of the Basket decreases from the Initial Basket Level of 100.00 to a Final Basket Level of 50.00, resulting in a Basket Return of -50.00%.

Because the Notes are not automatically called and the Final Basket Level is less than the Buffer Value and the Basket Return is -50.00%, the investor receives a payment at maturity of $588.24 per $1,000 principal amount Note, calculated as follows:

$1,000 + [$1,000 × (Basket Return + Buffer Percentage) × Downside Leverage Factor]

$1,000 + [$1,000 × (-50.00% + 15%) × 1.17647] = $588.24

The total return on the Notes is -41.176%.

PS-6 

Selected Purchase Considerations

The Notes are not appropriate for all investors. The Notes may be an appropriate investment for you if all of the following statements are true:

· You do not seek an investment that produces periodic interest or coupon payments or other sources of current income.

· You seek the potential for a fixed return equal to the call premium included in the Call Price if the Basket Level on the Review Date is greater than or equal to the Initial Basket Level.

· You understand and accept that, if the Notes are automatically called, the return on the Notes will be limited by the Call Price and you will not participate in any appreciation in the value of the Basket, which may be significant.

· You anticipate that, if the Notes are not automatically called, the Final Basket Level will be greater than the Initial Basket Level, and you are willing and able to accept the risk that, if the Notes are not automatically called and the Final Basket Level is less than the Buffer Value, you will lose some or all of your investment at maturity.

· You are willing and able to accept the risks associated with an investment linked to the performance of the Basket, as explained in more detail in the “Selected Risk Considerations” section of this pricing supplement.

· You understand and accept that you will not be entitled to receive dividends or distributions that may be paid to holders of the Basket Components, nor will you have any voting rights with respect to the Basket Components.

· You are willing and able to accept the risk that the Notes may be automatically called prior to scheduled maturity and that you may not be able to reinvest your money in an alternative investment with comparable risk and yield.

· You do not seek an investment for which there will be an active secondary market and you are willing and able to hold the Notes to maturity if the Notes are not automatically called.

· You are willing and able to assume our credit risk for all payments on the Notes.

· You are willing and able to consent to the exercise of any U.K. Bail-in Power by any relevant U.K. resolution authority.

The Notes may not be an appropriate investment for you if any of the following statements are true:

· You seek an investment that produces periodic interest or coupon payments or other sources of current income.

· You seek an investment that provides for the full repayment of principal at maturity.

· You are unwilling or unable to accept that, if the Notes are automatically called, the return on the Notes will be limited by the Call Price and you will not participate in any appreciation in the value of the Basket, which may be significant.

· You anticipate that, if the Notes are not automatically called, the Final Basket Level will be less than the Initial Basket Level, or you are unwilling or unable to accept the risk that, if the Notes are not automatically called and the Final Basket Level is less than the Buffer Value, you will lose some or all of your investment at maturity.

· You are unwilling or unable to accept the risks associated with an investment linked to the performance of the Basket, as explained in more detail in the “Selected Risk Considerations” section of this pricing supplement.

· You seek an investment that entitles you to dividends or distributions on, or voting rights related to, the Basket Components.

· You are unwilling or unable to accept the risk that the Notes may be automatically called prior to scheduled maturity.

· You seek an investment for which there will be an active secondary market and/or you are unwilling or unable to hold the Notes to maturity if they are not automatically called.

· You are unwilling or unable to assume our credit risk for all payments on the Notes.

· You are unwilling or unable to consent to the exercise of any U.K. Bail-in Power by any relevant U.K. resolution authority.

You must rely on your own evaluation of the merits of an investment in the Notes. You should reach a decision whether to invest in the Notes after carefully considering, with your advisors, the appropriateness of the Notes in light of your investment objectives and the specific information set forth in this pricing supplement, the prospectus and the prospectus supplement. Neither the Issuer nor Barclays Capital Inc. makes any recommendation as to the appropriateness of the Notes for investment.

PS-7 

Tax Consequences

You should review carefully the sections in the accompanying prospectus supplement entitled “Material U.S. Federal Income Tax Consequences—Tax Consequences to U.S. Holders—Notes Treated as Prepaid Forward Contracts” and, if you are a non-U.S. holder, “—Tax Consequences to Non-U.S. Holders.” The following discussion, when read in combination with those sections, constitutes the full opinion of our special tax counsel, Davis Polk & Wardwell LLP, regarding the material U.S. federal income tax consequences of owning and disposing of the Notes.

Based on current market conditions, in the opinion of our special tax counsel, the Notes should be treated for U.S. federal income tax purposes as prepaid forward contracts with respect to the Basket. Assuming this treatment is respected, upon a sale or exchange of the Notes (including redemption upon an automatic call or at maturity), you should recognize capital gain or loss equal to the difference between the amount realized on the sale or exchange and your tax basis in the Notes, which should equal the amount you paid to acquire the Notes. This gain or loss on your Notes should be treated as long-term capital gain or loss if you hold your Notes for more than a year, whether or not you are an initial purchaser of Notes at the original issue price. However, the Internal Revenue Service (the “IRS”) or a court may not respect this treatment, in which case the timing and character of any income or loss on the Notes could be materially and adversely affected. In addition, in 2007 the U.S. Treasury Department and the IRS released a notice requesting comments on the U.S. federal income tax treatment of “prepaid forward contracts” and similar instruments. The notice focuses in particular on whether to require investors in these instruments to accrue income over the term of their investment. It also asks for comments on a number of related topics, including the character of income or loss with respect to these instruments; the relevance of factors such as the nature of the underlying property to which the instruments are linked; the degree, if any, to which income (including any mandated accruals) realized by non-U.S. investors should be subject to withholding tax; and whether these instruments are or should be subject to the “constructive ownership” regime, which very generally can operate to recharacterize certain long-term capital gain as ordinary income and impose a notional interest charge. While the notice requests comments on appropriate transition rules and effective dates, any Treasury regulations or other guidance promulgated after consideration of these issues could materially and adversely affect the tax consequences of an investment in the Notes, possibly with retroactive effect. You should consult your tax advisor regarding the U.S. federal income tax consequences of an investment in the Notes, including possible alternative treatments and the issues presented by this notice.

Treasury regulations under Section 871(m) generally impose a withholding tax on certain “dividend equivalents” under certain “equity linked instruments.” A recent IRS notice excludes from the scope of Section 871(m) instruments issued prior to January 1, 2027 that do not have a “delta of one” with respect to underlying securities that could pay U.S.-source dividends for U.S. federal income tax purposes (each an “Underlying Security”). Based on our determination that the Notes do not have a “delta of one” within the meaning of the regulations, we expect that these regulations will not apply to the Notes with regard to non-U.S. holders. Our determination is not binding on the IRS, and the IRS may disagree with this determination. Section 871(m) is complex and its application may depend on your particular circumstances, including whether you enter into other transactions with respect to an Underlying Security. If necessary, further information regarding the potential application of Section 871(m) will be provided in the pricing supplement for the Notes. You should consult your tax advisor regarding the potential application of Section 871(m) to the Notes.

We will not attempt to ascertain whether the issuer of any Basket Component is treated as a “United States real property holding corporation” (a “USRPHC”) within the meaning of Code Section 897. As discussed in the section in the accompanying prospectus supplement entitled “Material U.S. Federal Income Tax Consequences -- FIRPTA,” if the issuer of any Basket Component were so treated, certain adverse U.S. federal income tax consequences might apply to a non-U.S. investor upon the sale, exchange or retirement of the Notes. If you are a non-U.S. investor you should refer to information filed with the Securities and Exchange Commission or an equivalent governmental authority by the issuers of the Basket Components and consult your tax advisor regarding the possible consequences to you if the issuer of any Basket Component is a USRPHC.

PS-8 

Selected Risk Considerations

An investment in the Notes involves significant risks. Investing in the Notes is not equivalent to investing directly in the Basket Components. Some of the risks that apply to an investment in the Notes are summarized below, but we urge you to read the more detailed explanation of risks relating to the Notes generally in the “Risk Factors” section of the prospectus supplement. You should not purchase the Notes unless you understand and can bear the risks of investing in the Notes.

Risks Relating to the Notes Generally

· You May Lose Some or All of Your Principal — The Notes differ from ordinary debt securities in that the Issuer will not necessarily pay the full principal amount at maturity. If the Notes are not automatically called and the Final Basket Level is less than the Buffer Value, you will lose 1.17647% of the principal amount of your Notes for every 1% that the Final Basket Level is less than the Buffer Value. Accordingly, if the Notes are not automatically called and the Final Basket Level is less than the Buffer Value, the Notes will be exposed on a leveraged basis to the decline in the value of the Basket below the Buffer Value and you will lose some or all of your investment at maturity.

· No Interest Payments — As a holder of the Notes, you will not receive interest payments.

· If the Notes Are Automatically Called, Your Maximum Gain on the Notes Will Be Limited to the Call Price — If your Notes are automatically called, the return on your Notes will not exceed the Call Price, regardless of any appreciation in the value of the Basket, which may be significant. If, as of the Review Date, the Basket has appreciated from the Initial Basket Level by more than the call premium percentage represented by the Call Price, you will receive a lower return on the Notes than you would have received if you had invested directly in the Basket.

· Reinvestment Risk — If your Notes are automatically called early, the term of the Notes could be as short as approximately 54 weeks. There is no guarantee that you would be able to reinvest the proceeds from an investment in the Notes in a comparable investment with a similar level of risk in the event the Notes are automatically called prior to the Maturity Date. For the avoidance of doubt, the fees and commissions described on the cover of this pricing supplement will not be rebated if the Notes are automatically called prior to the Maturity Date.

· The Performance of the Basket Components May Offset Each Other; Correlation (or Lack of Correlation) Among the Basket Components May Adversely Affect the Return on the Notes — The Basket Return will be calculated based on the weighted average performance of the Basket Components, as described on the cover of this pricing supplement. The lesser performance of some Basket Components will mitigate, and may completely offset, the greater performance of other Basket Components. You may lose a significant portion of your investment even if one or more Basket Components performs positively.

Correlation is a measure of the degree to which the returns of a pair of assets are similar to each other over a given period in terms of timing and direction. Movements in the values of the Basket Components may not correlate with each other. At a time when the value of a Basket Component increases in value, the value of other Basket Components may not increase as much or may even decline in value. In addition, high correlation of movements in the values of Basket Components could adversely affect your return during periods of decline for the Basket Components. Changes in the values of the Basket Components and/or the correlation among them may adversely affect the market value of, and any payments on, your Notes.

· Any Payment on the Notes Will Be Determined Based on the Closing Prices of the Basket Components on the Dates Specified — Any payment on the Notes will be determined based on the Closing Prices of the Basket Components on the dates specified. You will not benefit from any more favorable values of the Basket Components determined at any other time.

· Contingent Repayment of Principal Applies Only at Maturity or upon Any Automatic Call — You should be willing to hold your Notes to maturity or any automatic call. If you sell your Notes prior to maturity in the secondary market, if any, you may have to sell your Notes at a loss relative to your initial investment even if at that time the value of the Basket is greater than or equal to the Buffer Value. See “—Risks Relating to the Estimated Value of the Notes and the Secondary Market—Many Economic and Market Factors Will Impact the Value of the Notes” below.

· The Notes Are Subject to Volatility Risk — Volatility is a measure of the degree of variation in the level of the Basket over a period of time. The Call Price is determined based on a number of factors, including the expected volatility of the Basket. The Call Price represents a rate of return that is higher than the fixed rate that we would pay on a conventional debt security of the same tenor and is higher than it otherwise would have been had the expected volatility of the Basket been lower. As volatility of the Basket increases, there will typically be a greater likelihood that the Final Basket Level will be less than the Buffer Value.

Accordingly, you should understand that a higher Call Price reflects, among other things, an indication of a greater likelihood that you will incur a loss of principal at maturity than would have been the case had the Call Price been lower. In addition, actual volatility over the term of the Notes may be significantly higher than the expected volatility at the time the terms of the Notes were determined. If actual volatility is higher than expected, you will face an even greater risk that you will lose some or all of your principal at maturity for the reasons described above.

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· Owning the Notes Is Not the Same as Owning the Basket Components — The return on your Notes may not reflect the return you would realize if you actually owned the Basket Components. As a holder of the Notes, you will not have voting rights, rights to receive cash dividends or any other distributions or other rights that holders of the Basket Components would have.

· The U.S. Federal Income Tax Consequences of an Investment in the Notes Are Uncertain — There is no direct legal authority regarding the proper U.S. federal income tax treatment of the Notes, and we do not plan to request a ruling from the IRS. Consequently, significant aspects of the tax treatment of the Notes are uncertain, and the IRS or a court might not agree with the treatment of the Notes as prepaid forward contracts, as described above under “Tax Consequences.” If the IRS were successful in asserting an alternative treatment for the Notes, the tax consequences of the ownership and disposition of the Notes could be materially and adversely affected.

In addition, in 2007 the Treasury Department and the IRS released a notice requesting comments on various issues regarding the U.S. federal income tax treatment of “prepaid forward contracts” and similar instruments. Any Treasury regulations or other guidance promulgated after consideration of these issues could materially and adversely affect the tax consequences of an investment in the Notes, possibly with retroactive effect. You should review carefully the sections of the accompanying prospectus supplement entitled “Material U.S. Federal Income Tax Consequences—Tax Consequences to U.S. Holders—Notes Treated as Prepaid Forward Contracts” and, if you are a non-U.S. holder, “—Tax Consequences to Non-U.S. Holders,” and consult your tax advisor regarding the U.S. federal tax consequences of an investment in the Notes (including possible alternative treatments and the issues presented by the 2007 notice), as well as tax consequences arising under the laws of any state, local or non-U.S. taxing jurisdiction.

Risks Relating to the Issuer

· Credit of Issuer — The Notes are unsecured and unsubordinated debt obligations of the Issuer, Barclays Bank PLC, and are not, either directly or indirectly, an obligation of any third party. Any payment to be made on the Notes, including any repayment of principal, is subject to the ability of Barclays Bank PLC to satisfy its obligations as they come due and is not guaranteed by any third party. As a result, the actual and perceived creditworthiness of Barclays Bank PLC may affect the market value of the Notes and, in the event Barclays Bank PLC were to default on its obligations, you might not receive any amount owed to you under the terms of the Notes.

· You May Lose Some or All of Your Investment If Any U.K. Bail-in Power Is Exercised by the Relevant U.K. Resolution Authority — Notwithstanding and to the exclusion of any other term of the Notes or any other agreements, arrangements or understandings between Barclays Bank PLC and any holder or beneficial owner of the Notes (or the trustee on behalf of the holders of the Notes), by acquiring the Notes, each holder or beneficial owner of the Notes acknowledges, accepts, agrees to be bound by, and consents to the exercise of, any U.K. Bail-in Power by the relevant U.K. resolution authority as set forth under “Consent to U.K. Bail-in Power” in this pricing supplement. Accordingly, any U.K. Bail-in Power may be exercised in such a manner as to result in you and other holders and beneficial owners of the Notes losing all or a part of the value of your investment in the Notes or receiving a different security from the Notes, which may be worth significantly less than the Notes and which may have significantly fewer protections than those typically afforded to debt securities. Moreover, the relevant U.K. resolution authority may exercise the U.K. Bail-in Power without providing any advance notice to, or requiring the consent of, the holders and beneficial owners of the Notes. The exercise of any U.K. Bail-in Power by the relevant U.K. resolution authority with respect to the Notes will not be a default or an Event of Default (as each term is defined in the senior debt securities indenture) and the trustee will not be liable for any action that the trustee takes, or abstains from taking, in either case, in accordance with the exercise of the U.K. Bail-in Power by the relevant U.K. resolution authority with respect to the Notes. See “Consent to U.K. Bail-in Power” in this pricing supplement as well as “U.K. Bail-in Power,” “Risk Factors—Risks Relating to the Securities Generally—Regulatory action in the event a bank or investment firm in the Group is failing or likely to fail, including the exercise by the relevant U.K. resolution authority of a variety of statutory resolution powers, could materially adversely affect the value of any securities” and “Risk Factors—Risks Relating to the Securities Generally—Under the terms of the securities, you have agreed to be bound by the exercise of any U.K. Bail-in Power by the relevant U.K. resolution authority” in the accompanying prospectus supplement.

Risks Relating to the Basket Components

· Single Equities Risk — The value of each Basket Component can rise or fall sharply due to factors specific to that Basket Component and its issuer, such as stock price volatility, earnings, financial conditions, corporate, industry and regulatory developments, management changes and decisions and other events, as well as general market factors, such as general stock market volatility and levels, interest rates and economic and political conditions. We urge you to review financial and other information filed periodically with the SEC by the issuer of each Basket Component.

· The ETN Basket Component Has Risks Associated with Non-U.S. Companies—An investment linked to the value of securities issued by non-U.S. companies, such as the ETN Basket Component, which is issued by a company incorporated under the laws of Ireland with its principal executive offices located in Ireland, involves risks associated with Ireland. The

PS-10 

prices of such company’s securities may be affected by political, economic, financial and social factors in such countries, including changes in Irish government, economic and fiscal policies, currency exchange laws or other laws or restrictions.

· Anti-dilution Protection Is Limited, and the Calculation Agent Has Discretion to Make Anti-dilution Adjustments —The Calculation Agent may in its sole discretion make adjustments affecting the amounts payable on the Notes upon the occurrence of certain corporate events (such as stock splits or extraordinary or special dividends) that the Calculation Agent determines have a diluting or concentrative effect on the theoretical value of a Basket Component. However, the Calculation Agent might not make such adjustments in response to all events that could affect a Basket Component. The occurrence of any such event and any adjustment made by the Calculation Agent (or a determination by the Calculation Agent not to make any adjustment) may adversely affect the market price of, and any amounts payable on, the Notes. See “Reference Assets—Equity Securities—Share Adjustments Relating to Securities with an Equity Security as a Reference Asset” in the accompanying prospectus supplement.

· Reorganization or Other Events Could Adversely Affect the Value of the Notes or Result in the Notes Being Accelerated — Upon the occurrence of certain reorganization events or a nationalization, expropriation, liquidation, bankruptcy, insolvency or de-listing of a Basket Component, the Calculation Agent may replace that Basket Component with shares of another company identified as described in the prospectus supplement or, in some cases, with shares, cash or other assets distributed to holders of that Basket Component upon the occurrence of that event. In the alternative, the Calculation Agent may accelerate the Maturity Date for a payment determined by the Calculation Agent or may make other changes to the terms of the Notes to account for the occurrence of that event. Any decision by the Calculation Agent to replace a Basket Component, to accelerate the Notes or to otherwise adjust the terms of the Notes could adversely affect the value of, and any amount payable on, the Notes, perhaps significantly, and could result in a significantly lower return on the Notes than if the Calculation Agent had made a different decision. See “Reference Assets—Equity Securities—Share Adjustments Relating to Securities with an Equity Security as a Reference Asset” in the accompanying prospectus supplement.

· We May Accelerate the Notes If a Change-in-Law Event Occurs — Upon the occurrence of legal or regulatory changes that may, among other things, prohibit or otherwise materially restrict persons from holding the Notes or a Basket Component, or engaging in transactions in them, the Calculation Agent may determine that a change-in-law event has occurred and accelerate the Maturity Date for a payment determined by the Calculation Agent in its sole discretion. Any amount payable upon acceleration could be significantly less than any amount that would be due on the Notes if they were not accelerated. However, if the Calculation Agent elects not to accelerate the Notes, the value of, and any amount payable on, the Notes could be adversely affected, perhaps significantly, by the occurrence of those legal or regulatory changes. See “Terms of the Notes—Change-in-Law Events” in the accompanying prospectus supplement.

Risks Relating to Conflicts of Interest

· We and Our Affiliates May Engage in Various Activities or Make Determinations That Could Materially Affect Your Notes in Various Ways and Create Conflicts of Interest — We and our affiliates play a variety of roles in connection with the issuance of the Notes, as described below. In performing these roles, our and our affiliates’ economic interests are potentially adverse to your interests as an investor in the Notes.

In connection with our normal business activities and in connection with hedging our obligations under the Notes, we and our affiliates make markets in and trade various financial instruments or products for our accounts and for the account of our clients and otherwise provide investment banking and other financial services with respect to these financial instruments and products. These financial instruments and products may include securities, derivative instruments or assets that may relate to a Basket Component. In any such market making, trading and hedging activity, investment banking and other financial services, we or our affiliates may take positions or take actions that are inconsistent with, or adverse to, the investment objectives of the holders of the Notes. We and our affiliates have no obligation to take the needs of any buyer, seller or holder of the Notes into account in conducting these activities. Such market making, trading and hedging activity, investment banking and other financial services may negatively impact the value of the Notes.

In addition, the role played by Barclays Capital Inc., as the agent for the Notes, could present significant conflicts of interest with the role of Barclays Bank PLC, as issuer of the Notes. For example, Barclays Capital Inc. or its representatives may derive compensation or financial benefit from the distribution of the Notes and such compensation or financial benefit may serve as an incentive to sell the Notes instead of other investments. Furthermore, we and our affiliates establish the offering price of the Notes for initial sale to the public, and the offering price is not based upon any independent verification or valuation.

In addition to the activities described above, we will also act as the Calculation Agent for the Notes. As Calculation Agent, we will determine any values of the Basket Components and make any other determinations necessary to calculate any payments on the Notes. In making these determinations, we may be required to make discretionary judgments, including those described in the accompanying prospectus supplement and under “—Risks Relating to the Basket Components” above. In making these discretionary judgments, our economic interests are potentially adverse to your interests as an investor in the Notes, and any of these determinations may adversely affect any payments on the Notes.

PS-11 

Risks Relating to the Estimated Value of the Notes and the Secondary Market

· Lack of Liquidity — The Notes will not be listed on any securities exchange. Barclays Capital Inc. and other affiliates of Barclays Bank PLC intend to make a secondary market for the Notes but are not required to do so, and may discontinue any such secondary market making at any time, without notice. Barclays Capital Inc. may at any time hold unsold inventory, which may inhibit the development of a secondary market for the Notes. Even if there is a secondary market, it may not provide enough liquidity to allow you to trade or sell the Notes easily. Because other dealers are not likely to make a secondary market for the Notes, the price at which you may be able to trade your Notes is likely to depend on the price, if any, at which Barclays Capital Inc. and other affiliates of Barclays Bank PLC are willing to buy the Notes. The Notes are not designed to be short-term trading instruments. Accordingly, you should be able and willing to hold your Notes to maturity.

· Many Economic and Market Factors Will Impact the Value of the Notes — In addition to the value of the Basket Components on any day, the value of the Notes will be affected by a number of economic and market factors that may either offset or magnify each other, including:

o the expected volatility of the Basket Components;

o correlation (or lack of correlation) of the Basket Components;

o the time to maturity of the Notes;

o the dividend rates on the Basket Components;

o interest and yield rates in the market generally;

o supply and demand for the Notes;

o a variety of economic, financial, political, regulatory and judicial events; and

o our creditworthiness, including actual or anticipated downgrades in our credit ratings.

· The Estimated Value of Your Notes Is Expected to Be Lower Than the Initial Issue Price of Your Notes — The estimated value of your Notes on the Pricing Date is expected to be lower, and may be significantly lower, than the initial issue price of your Notes. The difference between the initial issue price of your Notes and the estimated value of the Notes is expected as a result of certain factors, such as any sales commissions expected to be paid to Barclays Capital Inc. or another affiliate of ours, any selling concessions, discounts, commissions or fees expected to be allowed or paid to non-affiliated intermediaries, the estimated profit that we or any of our affiliates expect to earn in connection with structuring the Notes, the estimated cost that we may incur in hedging our obligations under the Notes, and estimated development and other costs that we may incur in connection with the Notes.

· The Estimated Value of Your Notes Might Be Lower If Such Estimated Value Were Based on the Levels at Which Our Debt Securities Trade in the Secondary Market — The estimated value of your Notes on the Pricing Date is based on a number of variables, including our internal funding rates. Our internal funding rates may vary from the levels at which our benchmark debt securities trade in the secondary market. As a result of this difference, the estimated values referenced above might be lower if such estimated values were based on the levels at which our benchmark debt securities trade in the secondary market.

· The Estimated Value of the Notes Is Based on Our Internal Pricing Models, Which May Prove to Be Inaccurate and May Be Different from the Pricing Models of Other Financial Institutions — The estimated value of your Notes on the Pricing Date is based on our internal pricing models, which take into account a number of variables and are based on a number of subjective assumptions, which may or may not materialize. These variables and assumptions are not evaluated or verified on an independent basis. Further, our pricing models may be different from other financial institutions’ pricing models and the methodologies used by us to estimate the value of the Notes may not be consistent with those of other financial institutions that may be purchasers or sellers of Notes in the secondary market. As a result, the secondary market price of your Notes may be materially different from the estimated value of the Notes determined by reference to our internal pricing models.

· The Estimated Value of Your Notes Is Not a Prediction of the Prices at Which You May Sell Your Notes in the Secondary Market, If Any, and Such Secondary Market Prices, If Any, Will Likely Be Lower Than the Initial Issue Price of Your Notes and May Be Lower Than the Estimated Value of Your Notes — The estimated value of the Notes will not be a prediction of the prices at which Barclays Capital Inc., other affiliates of ours or third parties may be willing to purchase the Notes from you in secondary market transactions (if they are willing to purchase, which they are not obligated to do). The price at which you may be able to sell your Notes in the secondary market at any time will be influenced by many factors that cannot be predicted, such as market conditions, and any bid and ask spread for similar sized trades, and may be substantially less than our estimated value of the Notes. Further, as secondary market prices of your Notes take into account the levels at which our debt securities trade in the secondary market, and do not take into account our various costs related to the Notes such as fees, commissions, discounts, and the costs of hedging our obligations under the Notes, secondary market

PS-12 

prices of your Notes will likely be lower than the initial issue price of your Notes. As a result, the price at which Barclays Capital Inc., other affiliates of ours or third parties may be willing to purchase the Notes from you in secondary market transactions, if any, will likely be lower than the price you paid for your Notes, and any sale prior to the Maturity Date could result in a substantial loss to you.

· The Temporary Price at Which We May Initially Buy the Notes in the Secondary Market and the Value We May Initially Use for Customer Account Statements, If We Provide Any Customer Account Statements at All, May Not Be Indicative of Future Prices of Your Notes — Assuming that all relevant factors remain constant after the Pricing Date, the price at which Barclays Capital Inc. may initially buy or sell the Notes in the secondary market (if Barclays Capital Inc. makes a market in the Notes, which it is not obligated to do) and the value that we may initially use for customer account statements, if we provide any customer account statements at all, may exceed our estimated value of the Notes on the Pricing Date, as well as the secondary market value of the Notes, for a temporary period after the initial Issue Date of the Notes. The price at which Barclays Capital Inc. may initially buy or sell the Notes in the secondary market and the value that we may initially use for customer account statements may not be indicative of future prices of your Notes.

PS-13 

Information about the Basket

The Notes are linked to a basket consisting of the Basket Components. While historical information on the Basket does not exist for dates prior to the Pricing Date, the following graph sets forth the performance of the Basket from February 2, 2022 through October 15, 2025, assuming that, on February 2, 2022, the Basket was constructed with the specified weights for the Basket Components, the Initial Component Values were determined and the Initial Basket Level was set equal to 100. The dotted line indicates a hypothetical buffer level of 85.00% of the hypothetical level of the Basket on October 15, 2025.

We obtained the Closing Prices of each Basket Component used to calculate the graph below from Bloomberg Professional^® service (“Bloomberg”), without independent verification. The historical performance of the Basket should not be taken as an indication of future performance. Future performance of the Basket may differ significantly from historical performance, and no assurance can be given as to the level of the Basket during the term of the Notes, including on the Review Date or the Final Valuation Date. We cannot give you assurance that the performance of the Basket will not result in a loss on your initial investment.

The performance of the Basket will reflect the performance of the Basket Components. See “Selected Risk Considerations—The Performance of the Basket Components May Offset Each Other; Correlation (or Lack of Correlation) Among the Basket Components May Adversely Affect the Return on the Notes” above.

PS-14 

Information about the Basket Components

We urge you to read the following section in the accompanying prospectus supplement: “Reference Assets—Equity Securities—Reference Asset Issuer and Reference Asset Information.” Companies with securities registered under the Securities Exchange Act of 1934, as amended (the “Exchange Act”), are required to file financial and other information specified by the SEC periodically. Information provided to or filed with the SEC by the issuer of each Basket Component can be located on a website maintained by the SEC at http://www.sec.gov by reference to that issuer’s SEC file number provided below.

Included below is a brief description of the issuer of each Basket Component. This information has been obtained from publicly available sources. Information from outside sources is not incorporated by reference in, and should not be considered part of, this pricing supplement or the accompanying prospectus or prospectus supplement. We have not independently verified the accuracy or completeness of the information contained in outside sources.

Constellation Energy Corporation

According to publicly available information, Constellation Energy Corporation is a producer of emissions-free energy and an energy supplier to businesses, homes and public sector customers in the United States.

Information filed by Constellation Energy Corporation with the SEC under the Exchange Act can be located by reference to its SEC file number: 001-41137. The common stock of Constellation Energy Corporation is listed on The Nasdaq Stock Market under the ticker symbol “CEG.”

Historical Information

The graph below sets forth the historical performance of the CEG Basket Component from February 2, 2022 to October 15, 2025, based on the daily Closing Prices of the CEG Basket Component. The CEG Basket Component began trading on The Nasdaq Stock Market on February 2, 2022 and therefore has limited performance history. The Closing Price of the CEG Basket Component on October 15, 2025 was $403.95.

We obtained the Closing Prices of the CEG Basket Component from Bloomberg, without independent verification. Historical performance of the CEG Basket Component should not be taken as an indication of future performance. Future performance of the CEG Basket Component may differ significantly from historical performance, and no assurance can be given as to the Closing Price of the CEG Basket Component during the term of the Notes, including on the Review Date or the Final Valuation Date. We cannot give you assurance that the performance of the CEG Basket Component will not result in a loss on your initial investment. The Closing Prices below may reflect adjustments in response to certain corporate actions such as stock splits, public offerings, mergers and acquisitions, spin-offs, extraordinary dividends, delistings and bankruptcy.

PAST PERFORMANCE IS NOT INDICATIVE OF FUTURE RESULTS.

PS-15 

Equinix, Inc.

According to publicly available information, Equinix, Inc. is a digital infrastructure company that develops and operates data centers.

Information filed by Equinix, Inc. with the SEC under the Exchange Act can be located by reference to its SEC file number: 001-40205. The common stock of Equinix, Inc. is listed on The Nasdaq Stock Market under the ticker symbol “EQIX.”

Historical Information

The graph below sets forth the historical performance of the EQIX Basket Component from January 2, 2020 to October 15, 2025, based on the daily Closing Prices of the EQIX Basket Component. The Closing Price of the EQIX Basket Component on October 15, 2025 was $822.24.

We obtained the Closing Prices of the EQIX Basket Component from Bloomberg, without independent verification. Historical performance of the EQIX Basket Component should not be taken as an indication of future performance. Future performance of the EQIX Basket Component may differ significantly from historical performance, and no assurance can be given as to the Closing Price of the EQIX Basket Component during the term of the Notes, including on the Review Date or the Final Valuation Date. We cannot give you assurance that the performance of the EQIX Basket Component will not result in a loss on your initial investment. The Closing Prices below may reflect adjustments in response to certain corporate actions such as stock splits, public offerings, mergers and acquisitions, spin-offs, extraordinary dividends, delistings and bankruptcy.

PAST PERFORMANCE IS NOT INDICATIVE OF FUTURE RESULTS.

PS-16 

Eaton Corporation plc

According to publicly available information, Eaton Corporation plc, an Irish company, is a power management company that offers a range of power products for the data center, utility, industrial, commercial, machine building, residential, aerospace and mobility markets.

Information filed by Eaton Corporation plc. with the SEC under the Exchange Act can be located by reference to its SEC file number: 000-54863. The ordinary shares of Eaton Corporation plc are listed on the New York Stock Exchange under the ticker symbol “ETN.”

Historical Information

The graph below sets forth the historical performance of the ETN Basket Component from January 2, 2020 to October 15, 2025, based on the daily Closing Prices of the ETN Basket Component. The Closing Price of the ETN Basket Component on October 15, 2025 was $381.72.

We obtained the Closing Prices of the ETN Basket Component from Bloomberg, without independent verification. Historical performance of the ETN Basket Component should not be taken as an indication of future performance. Future performance of the ETN Basket Component may differ significantly from historical performance, and no assurance can be given as to the Closing Price of the ETN Basket Component during the term of the Notes, including on the Review Date or the Final Valuation Date. We cannot give you assurance that the performance of the ETN Basket Component will not result in a loss on your initial investment. The Closing Prices below may reflect adjustments in response to certain corporate actions such as stock splits, public offerings, mergers and acquisitions, spin-offs, extraordinary dividends, delistings and bankruptcy..

PAST PERFORMANCE IS NOT INDICATIVE OF FUTURE RESULTS.

PS-17 

Freeport-McMoRan Inc.

According to publicly available information, Freeport-McMoRan Inc. is an international metals company that operates assets with mineral reserves of copper, gold and molybdenum.

Information filed by Freeport-McMoRan Inc. with the SEC under the Exchange Act can be located by reference to its SEC file number: 001-11307-01. The common stock of Freeport-McMoRan Inc. is listed on the New York Stock Exchange under the ticker symbol “FCX.”

Historical Information

The graph below sets forth the historical performance of the FCX Basket Component from January 2, 2020 to October 15, 2025, based on the daily Closing Prices of the FCX Basket Component. The Closing Price of the FCX Basket Component on October 15, 2025 was $41.71.

We obtained the Closing Prices of the FCX Basket Component from Bloomberg, without independent verification. Historical performance of the FCX Basket Component should not be taken as an indication of future performance. Future performance of the FCX Basket Component may differ significantly from historical performance, and no assurance can be given as to the Closing Price of the FCX Basket Component during the term of the Notes, including on the Review Date or the Final Valuation Date. We cannot give you assurance that the performance of the FCX Basket Component will not result in a loss on your initial investment. The Closing Prices below may reflect adjustments in response to certain corporate actions such as stock splits, public offerings, mergers and acquisitions, spin-offs, extraordinary dividends, delistings and bankruptcy..

PAST PERFORMANCE IS NOT INDICATIVE OF FUTURE RESULTS.

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NextEra Energy, Inc.

According to publicly available information, NextEra Energy, Inc. is an electric power and energy infrastructure company and a participant in the renewable energy industry.

Information filed by NextEra Energy, Inc. with the SEC under the Exchange Act can be located by reference to its SEC file number: 001-08841. The common stock of NextEra Energy, Inc. Corporation is listed on the New York Stock Exchange under the ticker symbol “NEE.”

Historical Information

The graph below sets forth the historical performance of the NEE Basket Component from January 2, 2020 to October 15, 2025, based on the daily Closing Prices of the NEE Basket Component. The Closing Price of the NEE Basket Component on October 15, 2025 was $85.79.

We obtained the Closing Prices of the NEE Basket Component from Bloomberg, without independent verification. Historical performance of the NEE Basket Component should not be taken as an indication of future performance. Future performance of the NEE Basket Component may differ significantly from historical performance, and no assurance can be given as to the Closing Price of the NEE Basket Component during the term of the Notes, including on the Review Date or the Final Valuation Date. We cannot give you assurance that the performance of the NEE Basket Component will not result in a loss on your initial investment. The Closing Prices below may reflect adjustments in response to certain corporate actions such as stock splits, public offerings, mergers and acquisitions, spin-offs, extraordinary dividends, delistings and bankruptcy.

PAST PERFORMANCE IS NOT INDICATIVE OF FUTURE RESULTS.

PS-19 

Quanta Services, Inc.

According to publicly available information, Quanta Services, Inc. is a provider of infrastructure products and services for the electric and gas utility, renewable energy, technology, communications, pipeline and energy industries.

Information filed by Quanta Services, Inc. with the SEC under the Exchange Act can be located by reference to its SEC file number: 001-13831. The common stock of Quanta Services, Inc. is listed on the New York Stock Exchange under the ticker symbol “PWR.”

Historical Information

The graph below sets forth the historical performance of the PWR Basket Component from January 2, 2020 to October 15, 2025, based on the daily Closing Prices of the PWR Basket Component. The Closing Price of the PWR Basket Component on October 15, 2025 was $436.93.

We obtained the Closing Prices of the PWR Basket Component from Bloomberg, without independent verification. Historical performance of the PWR Basket Component should not be taken as an indication of future performance. Future performance of the PWR Basket Component may differ significantly from historical performance, and no assurance can be given as to the Closing Price of the PWR Basket Component during the term of the Notes, including on the Review Date or the Final Valuation Date. We cannot give you assurance that the performance of the PWR Basket Component will not result in a loss on your initial investment. The Closing Prices below may reflect adjustments in response to certain corporate actions such as stock splits, public offerings, mergers and acquisitions, spin-offs, extraordinary dividends, delistings and bankruptcy.

PAST PERFORMANCE IS NOT INDICATIVE OF FUTURE RESULTS.

PS-20 

Vertiv Holdings Co

According to publicly available information, Vertiv Holdings Co designs, manufactures and services digital infrastructure for data centers, communication networks and commercial and industrial environments.

Information filed by Vertiv Holdings Co with the SEC under the Exchange Act can be located by reference to its SEC file number: 001-38518. The Class A common stock of Vertiv Holdings Co is listed on the New York Stock Exchange under the ticker symbol “VRT.”

Historical Information

The graph below sets forth the historical performance of the VRT Basket Component from February 10, 2020 to October 15, 2025, based on the daily Closing Prices of the VRT Basket Component. The VRT Basket Component began trading on the New York Stock Exchange on February 10, 2020 following a merger with a special purpose acquisition company and therefore has limited performance history. The Closing Price of the VRT Basket Component on October 15, 2025 was $180.51.

We obtained the Closing Prices of the VRT Basket Component from Bloomberg, without independent verification. Historical performance of the VRT Basket Component should not be taken as an indication of future performance. Future performance of the VRT Basket Component may differ significantly from historical performance, and no assurance can be given as to the Closing Price of the VRT Basket Component during the term of the Notes, including on the Review Date or the Final Valuation Date. We cannot give you assurance that the performance of the VRT Basket Component will not result in a loss on your initial investment. The Closing Prices below may reflect adjustments in response to certain corporate actions such as stock splits, public offerings, mergers and acquisitions, spin-offs, extraordinary dividends, delistings and bankruptcy.

PAST PERFORMANCE IS NOT INDICATIVE OF FUTURE RESULTS.

PS-21 

Vistra Corp.

According to publicly available information, Vistra Corp. is an integrated retail electricity and power generation company that sells electricity and natural gas to residential, commercial and industrial retail customers.

Information filed by Vistra Corp. with the SEC under the Exchange Act can be located by reference to its SEC file number: 001-38086. The common stock of Vistra Corp. is listed on the New York Stock Exchange under the ticker symbol “VST.”

Historical Information

The graph below sets forth the historical performance of the VST Basket Component from January 2, 2020 to October 15, 2025, based on the daily Closing Prices of the VST Basket Component. The Closing Price of the VST Basket Component on October 15, 2025 was $210.85.

We obtained the Closing Prices of the VST Basket Component from Bloomberg, without independent verification. Historical performance of the VST Basket Component should not be taken as an indication of future performance. Future performance of the VST Basket Component may differ significantly from historical performance, and no assurance can be given as to the Closing Price of the VST Basket Component during the term of the Notes, including on the Review Date or the Final Valuation Date. We cannot give you assurance that the performance of the VST Basket Component will not result in a loss on your initial investment. The Closing Prices below may reflect adjustments in response to certain corporate actions such as stock splits, public offerings, mergers and acquisitions, spin-offs, extraordinary dividends, delistings and bankruptcy.

PAST PERFORMANCE IS NOT INDICATIVE OF FUTURE RESULTS.

PS-22 

Certain Employee Retirement Income Security Act Considerations

Your purchase of a Note in an Individual Retirement Account (an “IRA”) will be deemed to be a representation and warranty by you, as a fiduciary of the IRA and also on behalf of the IRA, that (i) neither the Issuer, the placement agent nor any of their respective affiliates has or exercises any discretionary authority or control or acts in a fiduciary capacity with respect to the IRA assets used to purchase the Note or renders investment advice (within the meaning of Section 3(21)(A)(ii) of the Employee Retirement Income Security Act (“ERISA”)) with respect to any such IRA assets and (ii) in connection with the purchase of the Note, the IRA will pay no more than “adequate consideration” (within the meaning of Section 408(b)(17) of ERISA) and in connection with any redemption of the Note pursuant to its terms will receive at least adequate consideration, and, in making the foregoing representations and warranties, you have (x) applied sound business principles in determining whether fair market value will be paid, and (y) made such determination acting in good faith.

Additional Information Regarding Our Estimated Value of the Notes

The final terms for the Notes will be determined on the date the Notes are initially priced for sale to the public (the “Pricing Date”) based on prevailing market conditions on or prior to the Pricing Date, and will be communicated to investors either orally or in a final pricing supplement.

Our internal pricing models take into account a number of variables and are based on a number of subjective assumptions, which may or may not materialize, typically including volatility, interest rates and our internal funding rates. Our internal funding rates (which are our internally published borrowing rates based on variables, such as market benchmarks, our appetite for borrowing and our existing obligations coming to maturity) may vary from the levels at which our benchmark debt securities trade in the secondary market. Our estimated value on the Pricing Date is based on our internal funding rates. Our estimated value of the Notes might be lower if such valuation were based on the levels at which our benchmark debt securities trade in the secondary market.

Our estimated value of the Notes on the Pricing Date is expected to be less than the initial issue price of the Notes. The difference between the initial issue price of the Notes and our estimated value of the Notes is expected to result from several factors, including any sales commissions expected to be paid to Barclays Capital Inc. or another affiliate of ours, any selling concessions, discounts, commissions or fees expected to be allowed or paid to non-affiliated intermediaries, the estimated profit that we or any of our affiliates expect to earn in connection with structuring the Notes, the estimated cost that we may incur in hedging our obligations under the Notes, and estimated development and other costs that we may incur in connection with the Notes.

Our estimated value on the Pricing Date is not a prediction of the price at which the Notes may trade in the secondary market, nor will it be the price at which Barclays Capital Inc. may buy or sell the Notes in the secondary market. Subject to normal market and funding conditions, Barclays Capital Inc. or another affiliate of ours intends to offer to purchase the Notes in the secondary market but it is not obligated to do so.

Assuming that all relevant factors remain constant after the Pricing Date, the price at which Barclays Capital Inc. may initially buy or sell the Notes in the secondary market, if any, and the value that we may initially use for customer account statements, if we provide any customer account statements at all, may exceed our estimated value on the Pricing Date for a temporary period expected to be approximately six months after the initial Issue Date of the Notes because, in our discretion, we may elect to effectively reimburse to investors a portion of the estimated cost of hedging our obligations under the Notes and other costs in connection with the Notes that we will no longer expect to incur over the term of the Notes. We made such discretionary election and determined this temporary reimbursement period on the basis of a number of factors, which may include the tenor of the Notes and/or any agreement we may have with the distributors of the Notes. The amount of our estimated costs that we effectively reimburse to investors in this way may not be allocated ratably throughout the reimbursement period, and we may discontinue such reimbursement at any time or revise the duration of the reimbursement period after the initial Issue Date of the Notes based on changes in market conditions and other factors that cannot be predicted.

We urge you to read the “Selected Risk Considerations” beginning on page PS-9 of this pricing supplement.

You may revoke your offer to purchase the Notes at any time prior to the Pricing Date. We reserve the right to change the terms of, or reject any offer to purchase, the Notes prior to their Pricing Date. In the event of any changes to the terms of the Notes, we will notify you and you will be asked to accept such changes in connection with your purchase. You may also choose to reject such changes in which case we may reject your offer to purchase.

PS-23 

Supplemental Plan of Distribution

J.P. Morgan Securities LLC and JPMorgan Chase Bank, N.A. will act as placement agents for the Notes pursuant to separate placement agency agreements with the Issuer. The placement agents will forgo fees for sales to fiduciary accounts. The placement agents will receive a fee from the Issuer or one of its affiliates per Note as specified on the cover of this pricing supplement.

PS-24 

FAQ

What does Barclays’ 424B2 pricing supplement describe?

It details unsecured notes linked to an equal-weight basket of eight stocks with an automatic call feature and leveraged upside/downside.

How does the automatic call work?

If the Basket Level on the Review Date is at or above the Initial Basket Level, holders receive the Call Price of $1,160 per $1,000 note and the notes terminate.

What are the key leverage and buffer terms?

Upside Leverage Factor 1.25; Buffer 15.00% (Buffer Value 85); below the buffer, losses are scaled by a 1.17647 Downside Leverage Factor.

Which stocks are in the basket and how are they weighted?

CEG, EQIX, ETN, FCX, NEE, PWR, VRT, VST; each at 12.50% weight.

What are the key dates for these notes?

Review Date October 30, 2026; Call Settlement Date November 4, 2026; Final Valuation Date October 18, 2027; Maturity October 21, 2027.

Are the notes listed or guaranteed by any agency?

They will not be listed on any U.S. exchange and are unsecured obligations of Barclays; no FDIC or FSCS insurance applies.

Are there special regulatory or tax considerations?

Holders consent to U.K. Bail-in Power. For U.S. tax, the notes are expected to be treated as prepaid forward contracts, per counsel’s opinion.