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ArriVent BioPharma, Inc. filings document a Nasdaq-listed clinical-stage oncology company with common stock registered under the Exchange Act. Its Form 8-K reports cover financial results, Regulation FD disclosures, clinical and preclinical program announcements, conference presentations, IND-related updates, material-event disclosures, and exhibits tied to press releases.
Proxy materials describe stockholder voting matters, board elections, auditor ratification, annual meeting procedures, and governance information. The filing record also reflects capital-structure disclosures, emerging growth company status, material agreements, and risk-oriented disclosures associated with ArriVent's firmonertinib program and antibody-drug conjugate pipeline.
ArriVent BioPharma, Inc. filed a prospectus supplement tied to its existing at-the-market equity offering program. Under this supplement, the company may offer and sell shares of its common stock with an aggregate offering price of up to $250,000,000 from time to time through Jefferies LLC as sales agent.
The at-the-market sales are made under an Open Market Sale Agreement dated February 3, 2025, and are covered by ArriVent’s automatic shelf registration statement on Form S-3ASR, which became effective upon filing. The company also filed the sales agreement and related legal opinions as exhibits.
ArriVent BioPharma, Inc. is offering up to $250,000,000 of its common stock in an “at the market” (ATM) program through Jefferies LLC as sales agent. Shares may be sold from time to time at market prices; Jefferies may receive commissions up to 3.0%. The prospectus supplement cites a last reported sale price of $29.50 per share (May 8, 2026), and illustrates an issuance of 8,474,576 shares at that price. The document states shares outstanding were 45,308,941 as of March 31, 2026 and presents net tangible book value of $301.1 million (or $6.64 per share) and an illustrative as‑adjusted net tangible book value of $544.7 million (or $10.12 per share) after the assumed $250.0 million ATM sale. Net proceeds are stated to be used to support development of firmonertinib, other pipeline programs and general corporate purposes. Sales under the agreement are conditional, may occur at varying prices and times, and Jefferies may terminate or decline transaction instructions per the sales agreement terms.
ArriVent BioPharma reported first-quarter 2026 results showing continued investment in its oncology pipeline and a narrower loss. Net loss was $43.3 million, compared with $64.4 million a year earlier, driven mainly by lower early-stage R&D spending.
Research and development expense fell to $37.6 million from $61.3 million, while general and administrative costs rose to $8.5 million as the company scales public-company operations. ArriVent ended March 31, 2026 with $326.4 million in cash, cash equivalents and marketable securities and believes this will fund operations for at least 12 months.
Pipeline progress included ongoing Phase 3 trials of firmonertinib in EGFR-mutant NSCLC and a Phase 1 trial of antibody-drug conjugate ARR-217. The company also raised $54.7 million net by selling 2.4 million shares via its at-the-market equity program and retains access to an undrawn $75 million term loan facility.
ArriVent BioPharma reported first quarter 2026 results and highlighted progress across its oncology pipeline. The company is running two pivotal firmonertinib Phase 3 trials in uncommon EGFR-mutant non-small cell lung cancer, with topline monotherapy data in frontline EGFR exon 20 insertion NSCLC expected in mid-2026 and the global ALPACCA PACC-mutant study continuing enrollment.
ArriVent also advanced its antibody-drug conjugate programs: ARR-002 received FDA clearance of its IND, with initial clinical development planned in ovarian and endometrial cancers, and ARR-217 continues in a Phase 1 trial for gastrointestinal tumors. Management reiterated a projected cash runway into the fourth quarter of 2027.
Financially, for the quarter ended March 31, 2026, research and development expenses were $37.6 million versus $61.3 million a year earlier, while general and administrative expenses rose to $8.5 million from $5.5 million. Net loss narrowed to $43.3 million from $64.4 million, or $0.96 per share compared with $1.90 per share. Cash and cash equivalents were $62.1 million and short-term investments were $264.3 million as of March 31, 2026.
Arrivent Biopharma Inc ownership update: FMR LLC reports beneficial ownership of 3,016,131.87 shares of Common Stock, representing 6.8% of the class as disclosed on the cover information. The filing states voting and dispositive powers held by FMR LLC and identifies Abigail P. Johnson with dispositive power over the same shares.
The filing is an amendment to a Schedule 13G/A and includes Exhibit 99 and a power of attorney reference.
ArriVent BioPharma, Inc. is calling a virtual 2026 annual stockholder meeting on June 18, 2026 at 12:00 p.m. Eastern via www.virtualshareholdermeeting.com/AVBP2026. Stockholders will vote on electing three directors to three-year terms through 2029 and ratifying PricewaterhouseCoopers LLP as independent auditor for the year ending December 31, 2026.
Holders of 46,368,442 common shares outstanding as of April 21, 2026 may vote online, by phone, mail or during the webcast. The proxy details board structure, committee independence, major investors owning about 5–9% each, and 2025 executive pay, including $9.37 million in total compensation for CEO Zhengbin (Bing) Yao, largely in stock options.
ArriVent BioPharma, Inc. reported that it will present two preclinical poster presentations at the 2026 American Association for Cancer Research (AACR) Annual Meeting in San Diego from April 17-22. The information is furnished under Regulation FD and an accompanying press release is included as an exhibit.
One poster covers preclinical findings for EGFR inhibitor firmonertinib, including high-resolution crystal structure data that support an ongoing pivotal Phase 3 study in frontline EGFR exon 20 insertion mutant non-small cell lung cancer. The other focuses on ARR-002, a novel dual-target MUC16/NaPi2b tetravalent antibody drug conjugate for ovarian and endometrial cancers, describing its preclinical characterization and planned advancement toward clinical evaluation, with additional data to be highlighted in an oral mini-symposium presentation.
ArriVent BioPharma, Inc. reported that it will present two preclinical poster presentations at the 2026 American Association for Cancer Research (AACR) Annual Meeting in San Diego from April 17-22. The information is furnished under Regulation FD and an accompanying press release is included as an exhibit.
One poster covers preclinical findings for EGFR inhibitor firmonertinib, including high-resolution crystal structure data that support an ongoing pivotal Phase 3 study in frontline EGFR exon 20 insertion mutant non-small cell lung cancer. The other focuses on ARR-002, a novel dual-target MUC16/NaPi2b tetravalent antibody drug conjugate for ovarian and endometrial cancers, describing its preclinical characterization and planned advancement toward clinical evaluation, with additional data to be highlighted in an oral mini-symposium presentation.
ArriVent BioPharma, Inc. is a clinical-stage biopharmaceutical company focused on cancers driven by EGFR and related mutations, especially non-small cell lung cancer (NSCLC). Its lead oral drug, firmonertinib, targets both classical and uncommon EGFR mutations, including exon 20 insertions and PACC mutations.
Firmonertinib, licensed globally (ex‑Greater China) from Allist, has shown high response rates in Phase 1b studies. In treatment‑naive EGFR exon 20 insertion NSCLC, the FAVOUR trial reported a confirmed overall response rate of 79% and median duration of response of 15.2 months at 240 mg once daily. In PACC‑mutant NSCLC, the FURTHER trial reported a 68.2% confirmed response rate and 16.0‑month median progression‑free survival at 240 mg.
The company is running two pivotal global Phase 3 trials: FURVENT in first‑line exon 20 insertion NSCLC against platinum‑pemetrexed, and ALPACCA in first‑line PACC‑mutant NSCLC against investigator’s choice of osimertinib or afatinib. Firmonertinib has Breakthrough Therapy Designation for first‑line EGFR exon 20 insertion NSCLC and Orphan Drug Designation for NSCLC with several HER‑family mutations.
Beyond firmonertinib, ArriVent is building an oncology pipeline of antibody‑drug conjugates (ADCs). It is developing ARR‑217 (MRG007), a CDH17‑targeting ADC for gastrointestinal tumors under license from Lepu Biopharma, and advancing preclinical ADC candidate ARR‑002 via a platform collaboration with Aarvik. An additional ADC collaboration with Alphamab aims to generate novel ADCs using proprietary linker‑payload and glycan‑conjugation technologies.
ArriVent reported an aggregate market value of common stock held by non‑affiliates of $762,664,165 as of June 30, 2025, and 44,201,622 shares of common stock outstanding as of March 4, 2026.
ArriVent BioPharma, Inc. reported full year 2025 results and updated its oncology pipeline. The company is advancing firmonertinib through two global Phase 3 trials in first-line non-small cell lung cancer with uncommon EGFR mutations, with topline data from the exon 20 insertion study expected in mid-2026 and a projected cash runway into 3Q 2027.
For the year ended December 31, 2025, ArriVent recorded total operating expenses of 177,534 (in thousands), driven mainly by research and development expenses of 153,351 (in thousands), reflecting investment in firmonertinib and its ADC portfolio. The company reported a net loss of 166,308 (in thousands), compared with 80,488 (in thousands) in 2024, and total assets of 333,169 (in thousands), including cash, cash equivalents and investments.
Management highlighted continued progress for ARR-217, a CDH17-targeted antibody-drug conjugate in an ongoing Phase 1 trial for gastrointestinal tumors, and indicated plans to advance additional ADC candidates toward the clinic, broadening ArriVent’s focus beyond lung cancer into multiple solid tumors.