Janus Henderson Group (BCAX) reports 3.17M Bicara Therapeutics shares in 13G/A

Rhea-AI Filing Summary

Janus Henderson Group Ltd. reports beneficial ownership of Bicara Therapeutics Inc. common stock on a passive basis. Through its investment adviser subsidiaries managing various Managed Portfolios, it may be deemed to beneficially own 3,171,015 shares of common stock, representing 4.8% of the class. All voting and dispositive authority over these shares is shared among the relevant asset managers; none is held on a sole basis. Janus Henderson and its asset managers disclaim rights to receive dividends or sale proceeds, which belong to the Managed Portfolios. No individual Managed Portfolio holds more than five percent of Bicara’s common stock.

Key Figures

Beneficially owned shares: 3,171,015 shares Percent of class: 4.8% Shared voting power: 3,171,015 shares +3 more

6 metrics

Beneficially owned shares 3,171,015 shares Common stock of Bicara Therapeutics Inc. beneficially owned by Janus Henderson-related asset managers

Percent of class 4.8% Percentage of Bicara Therapeutics Inc. common stock class beneficially owned

Shared voting power 3,171,015 shares Shares over which Janus Henderson-related entities have shared power to vote or direct the vote

Shared dispositive power 3,171,015 shares Shares over which Janus Henderson-related entities have shared power to dispose or direct disposition

Sole voting power 0 shares Shares with sole power to vote or direct the vote

Sole dispositive power 0 shares Shares with sole power to dispose or direct disposition

Key Terms

beneficial owner, dispositive power, Managed Portfolios, parent holding company, +1 more

5 terms

beneficial owner financial

"may be deemed to be the beneficial owner of 3,171,015 common stock"

A beneficial owner is the person who ultimately owns or controls a financial asset or property, even if their name isn't directly on official documents. Think of it like someone who secretly holds the keys to a safe deposit box—others may appear to have access, but the true owner is the one who benefits from what's inside. Identifying beneficial owners helps ensure transparency and prevent illegal activities like money laundering or fraud.

dispositive power financial

"Shared Dispositive Power 3,171,015.00"

Dispositive power is the authority to decide the final outcome of an asset, legal claim, contract, or corporate action — in effect the power to dispose of or resolve something. For investors it matters because whoever holds that authority can determine who gets paid, who controls an asset or vote, and how risks and returns are allocated; think of it like holding the key that lets you lock in the winner or loser in a deal.

Managed Portfolios financial

"collectively referred to herein as Managed Portfolios"

parent holding company financial

"If a parent holding company has filed this schedule, pursuant to (ii)(G)"

Power of Attorney financial

"Exhibit 24: Power of Attorney"

A power of attorney is a legal document that allows one person to make decisions and act on behalf of another person, often in financial or legal matters. It’s like giving someone a trusted helper or agent the authority to handle important tasks if you are unable to do so yourself. This matters to investors because it can impact how their assets are managed or transferred if they become unable to oversee their affairs.

FAQ

What percentage of Bicara Therapeutics (BCAX) does Janus Henderson Group Ltd. report owning?

Janus Henderson Group Ltd. reports beneficial ownership of 4.8% of Bicara Therapeutics Inc.’s common stock, representing 3,171,015 shares held across various Managed Portfolios advised by its affiliated asset managers.

How many Bicara Therapeutics (BCAX) shares are beneficially owned by Janus Henderson-related entities?

Affiliates of Janus Henderson Group Ltd. may be deemed to beneficially own 3,171,015 Bicara Therapeutics Inc. common shares, with shared voting and shared dispositive power over the full amount through multiple investment adviser subsidiaries.

Does Janus Henderson Group Ltd. receive dividends from its Bicara Therapeutics (BCAX) holdings?

The filing states Janus Henderson’s asset managers do not have the right to receive dividends or sale proceeds; those rights belong to the respective Managed Portfolios that hold the Bicara Therapeutics Inc. shares.

Do any single Managed Portfolios hold over 5% of Bicara Therapeutics (BCAX) stock?

No individual Managed Portfolio holds more than 5% of Bicara Therapeutics Inc.’s common stock. The reported 4.8% stake is aggregated across multiple client accounts managed by Janus Henderson affiliates.

What voting and dispositive powers does Janus Henderson have over Bicara Therapeutics (BCAX) shares?

Janus Henderson-related asset managers report 0 shares with sole voting or dispositive power and 3,171,015 shares with shared voting and shared dispositive power regarding Bicara Therapeutics Inc. common stock.

Who signed the Bicara Therapeutics (BCAX) Schedule 13G/A on behalf of Janus Henderson?

The Schedule 13G/A amendment was signed by Kristin Mariani, identified as Head of North America Compliance, on behalf of Janus Henderson Group Ltd., referencing an attached Power of Attorney.

AI-generated analysis. How Rhea-AI works. Not financial advice.

See more from StockTitan in Google Search and AI answers. Adds StockTitan as a preferred source · opens Google

Add on Google Not now

Available on EDGAR 08/13/2026 - 12:43 PM Accepted by SEC EDGAR 08/13/2026 - 12:42 PM Learn about SEC filing dates

SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13G

UNDER THE SECURITIES EXCHANGE ACT OF 1934

(Amendment No. 1)

BICARA THERAPEUTICS INC.

(Name of Issuer)

Common Stock

(Title of Class of Securities)

055477103

(CUSIP Number)

06/30/2026

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

Rule 13d-1(b)

Rule 13d-1(c)

Rule 13d-1(d)

schemaVersion:

SCHEDULE 13G

CUSIP Number(s): 055477103

1

Names of Reporting Persons

JANUS HENDERSON GROUP Ltd.

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

JERSEY

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 3,171,015.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 3,171,015.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

3,171,015.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

4.8 %

12

Type of Reporting Person (See Instructions)

HC

SCHEDULE 13G

Item 1.
(a)	Name of issuer: BICARA THERAPEUTICS INC.
(b)	Address of issuer's principal executive offices: 116 HUNTINGTON AVENUE, SUITE 703 BOSTON, MA 02116
Item 2.
(a)	Name of person filing: Janus Henderson Group Ltd. In accordance with SEC Release No. 34-39538 (January 12, 1998), this Schedule 13G reflects the securities beneficially owned, or deemed to be beneficially owned, by Janus Henderson Group Ltd. It does not include securities, if any, beneficially owned by Janus Henderson Group Ltd.s ultimate parent Jupiter Topco LLC, the direct or indirect owners of Jupiter Topco LLC, or other persons that may be deemed under control of such owners. Any beneficial ownership by such persons has been disaggregated from that of Janus Henderson Group Ltd. in accordance with the release.
(b)	Address or principal business office or, if none, residence: 201 Bishopsgate EC2M 3AE, United Kingdom
(c)	Citizenship: Y9
(d)	Title of class of securities: Common Stock
(e)	CUSIP No.: 055477103
Item 3.	If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)	Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)	Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)	Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)	Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)	An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)	An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)	A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)	A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)	A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)	A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J), please specify the type of institution:
(k)	Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.	Ownership
(a)	Amount beneficially owned: Janus Henderson Group Ltd. (JHG) is the ultimate parent of a number of SEC-registered investment advisers and foreign equivalents thereof, including but not limited to Janus Henderson Investors US LLC, Janus Henderson Investors UK Limited, Janus Henderson Investors Australia Institutional Funds Management Limited, Janus Henderson Investors Middle East Limited, Janus Henderson Investors (Jersey) Limited, Janus Henderson Investors (Japan) Limited, Janus Henderson Investors (Singapore) Limited, Kapstream Capital Pty Limited, Privacore Capital Advisors LLC, Tabula Investment Management Limited, Victory Park Capital Advisors LLC, and Richard Berstein Advisors LLC (each, an Asset Manager and together, the Asset Managers). The Asset Managers generally exercise investment and/or voting discretion on behalf of their clients which include investment companies, other investment advisers, institutional separate accounts and retail separate accounts (collectively referred to herein as Managed Portfolios). As a result of their exercise of investment and/or voting discretion on behalf of the Managed Portfolios, the Asset Managers may be deemed to be the beneficial owner of 3,171,015 common stock of Bicara Therapeutics Inc. However, the Asset Managers do not have the right to receive any dividends from, or the proceeds from the sale of, the securities held in the Managed Portfolios and disclaim any ownership associated with such rights.
(b)	Percent of class: 4.8 %
(c)	Number of shares as to which the person has:
	(i) Sole power to vote or to direct the vote: 0
	(ii) Shared power to vote or to direct the vote: 3171015
	(iii) Sole power to dispose or to direct the disposition of: 0
	(iv) Shared power to dispose or to direct the disposition of: 3171015
Item 5.	Ownership of 5 Percent or Less of a Class.
	Not Applicable
Item 6.	Ownership of more than 5 Percent on Behalf of Another Person.
	If any other person is known to have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, such securities, a statement to that effect should be included in response to this item and, if such interest relates to more than 5 percent of the class, such person should be identified. A listing of the shareholders of an investment company registered under the Investment Company Act of 1940 or the beneficiaries of employee benefit plan, pension fund or endowment fund is not required. The Managed Portfolios have the right to receive all dividends from, and the proceeds from the sale of, the securities held in their respective accounts. Of the Managed Portfolios, none own more than five percent of the common stock of Bicara Therapeutics Inc.
Item 7.	Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
	If a parent holding company has filed this schedule, pursuant to Rule 13d-1(b)(ii)(G), so indicate under Item 3(g) and attach an exhibit stating the identity and the Item 3 classification of the relevant subsidiary. If a parent holding company has filed this schedule pursuant to Rule 13d-1(c) or Rule 13d-1(d), attach an exhibit stating the identification of the relevant subsidiary. Please refer to Exhibit 99.
Item 8.	Identification and Classification of Members of the Group.
	If a group has filed this schedule pursuant to §240.13d-1(b)(1)(ii)(J), so indicate under Item 3(j) and attach an exhibit stating the identity and Item 3 classification of each member of the group. If a group has filed this schedule pursuant to §240.13d-1(c) or §240.13d-1(d), attach an exhibit stating the identity of each member of the group. N/A
Item 9.	Notice of Dissolution of Group.
	Notice of dissolution of a group may be furnished as an exhibit stating the date of the dissolution and that all further filings with respect to transactions in the security reported on will be filed, if required, by members of the group, in their individual capacity. See Item 5. N/A

Item 10.

Certifications:

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

JANUS HENDERSON GROUP Ltd.

Signature:	Kristin Mariani
Name/Title:	Head of North America Compliance
Date:	08/13/2026

Exhibit Information

Exhibit 24: Power of Attorney Exhibit 99: Item 7