STOCK TITAN

Biodexa (Nasdaq: BDRX) prices $3.5M ADS, pre-funded warrant and inducement deals

(Neutral)
(Neutral)
Form Type
6-K

Rhea-AI Filing Summary

Biodexa Pharmaceuticals PLC has priced a group of equity and warrant transactions expected to raise approximately $3.5 million in gross proceeds through a registered offering, a concurrent private placement and a warrant exercise inducement.

The deals combine sales of American depositary shares and pre-funded warrants at $2.85 per ADS (or $2.8499 per pre-funded warrant) with new Series M, N and O warrants that, once shareholder approval is obtained, will allow the investor to purchase additional ADSs over five years at the same exercise price. Certain existing Series L warrants will be exercised for cash at the reduced price of $2.85 in exchange for issuing Series O warrants at a 200% ratio to ADSs received.

The company has engaged Maxim Group LLC as exclusive placement and inducement agent, agreeing to pay an 8.0% cash fee on gross proceeds plus expenses, and has entered into a registration rights agreement to register resales of the warrants and the ADSs issuable upon their exercise.

Positive

  • None.

Negative

  • None.

Insights

Biodexa secures $3.5M via structured ADS and warrant financing.

Biodexa Pharmaceuticals is raising approximately $3.5 million through a mix of a registered ADS offering, a concurrent private placement of pre-funded warrants, and a warrant exercise inducement. All new warrants, including Series M, N and O, share a $2.85 per ADS exercise price.

The structure leans heavily on warrants: existing holders agree to exercise older Series L warrants for cash while receiving Series O warrants equal to 200% of the ADSs exercised. Additional Series M and N warrants are tied to the new offerings and become exercisable only after shareholder approval, with 5-year terms.

The transactions expand potential future share issuance, but precise dilution depends on how many of the Series M, N and O warrants and pre-funded warrants are ultimately exercised. Execution also depends on obtaining shareholder approval and satisfying closing conditions around July 1, 2026. Rating remains neutral given limited visibility on the company’s overall capital structure.

Expected gross proceeds $3.5 million Aggregate gross proceeds from offerings and warrant inducement
ADS / warrant price $2.85 per ADS Offering price and warrant exercise price
Pre-funded warrant price $2.8499 per warrant Private placement pre-funded warrants
Series M Warrants 282,952 ADSs ADSs purchasable upon exercise of Series M Warrants
Series N Warrants 701,754 ADSs ADSs purchasable upon exercise of Series N Warrants
Series O Warrants 1,219,512 ADSs ADSs purchasable upon exercise granted in inducement
Placement fee 8.0% of gross proceeds Cash fee payable to Maxim Group LLC
Private placement pre-funded warrants 350,877 ADSs Aggregate ADSs underlying private placement pre-funded warrants
pre-funded warrants financial
"The Private Offering consists of pre-funded warrants to purchase 350,877 ADSs at a combined offering price of $2.8499 per pre-funded warrant."
Pre-funded warrants are financial instruments that give investors the right to purchase a company's stock at a set price, but with most or all of the purchase price paid upfront. They function like a coupon or gift card for stock, allowing investors to buy shares later at a fixed price, which can be beneficial if they want to avoid future price increases. This makes them important for investors seeking flexibility and certainty in their investment plans.
Series M Warrants financial
"the investor will be issued (i) in connection with the Registered Offering, Series M warrants ("Series M Warrants") to purchase up to 282,952 ADSs"
Series N Warrants financial
"Series N warrants ("Series N Warrants," and together with the Series M Warrants and Series O Warrants, the "Warrants") to purchase up to 701,754 ADSs"
Series O Warrants financial
"issue new unregistered Series O warrants ("Series O Warrants") to purchase an aggregate of 1,219,512 ADSs."
Registration Rights Agreement financial
"The Company entered into a registration rights agreement (the "Registration Rights Agreement") with the Investor in which it agreed to file with the SEC a registration statement covering the resale of all of the Warrants and Warrant ADSs"
A registration rights agreement is a contract that gives investors the option to have their ownership stakes officially registered with the government, making it easier to sell their shares later. This agreement matters because it provides investors with a clearer path to cash out their investments if they choose, offering more liquidity and confidence in their ability to sell their holdings when desired.
warrant exercise inducement financial
"the Company entered into warrant exercise inducement letter agreement (the "Inducement Letter") with a holder of certain of the Company’s outstanding Series L warrants"
A warrant exercise inducement is an extra benefit offered to holders of warrants to persuade them to convert those warrants into shares sooner or at all. Think of it like a limited-time bonus or coupon that makes using the warrant more attractive; it matters to investors because it can increase the number of shares outstanding, dilute existing ownership, change control stakes, and alter a company’s cash or equity position.

AI-generated analysis. How Rhea-AI works. Not financial advice.

See more from StockTitan in Google Search and AI answers. Adds StockTitan as a preferred source · opens Google
Add on Google
Learn about SEC filing dates

FAQ

What is Biodexa Pharmaceuticals (BDRX) raising through its latest offerings?

Biodexa aims to raise approximately $3.5 million in gross proceeds through a registered ADS offering, a concurrent private placement of pre-funded warrants, and a warrant exercise inducement. This capital is earmarked for development programs, working capital and general corporate purposes.

How are the new Biodexa ADS and warrant offerings priced?

The registered ADS are priced at $2.85 per ADS, while pre-funded warrants in the private placement are priced at $2.8499 each. Newly issued Series M, N and O warrants all carry an exercise price of $2.85 per ADS and a five-year term after shareholder approval.

What are Biodexa’s new Series M, Series N and Series O warrants?

Series M and N warrants are issued alongside the registered and private offerings, and Series O warrants are granted as part of a warrant inducement. Together they cover millions of potential ADSs at $2.85 per ADS, exercisable for five years after required shareholder approval is obtained.

What is the purpose of Biodexa’s warrant inducement transaction?

Under the warrant inducement, a holder agrees to immediately exercise existing Series L warrants for cash at $2.85 per ADS. In return, Biodexa issues new unregistered Series O warrants to purchase 1,219,512 ADSs, equal to 200% of the ADSs issued from the exercised existing warrants.

What fees is Biodexa paying to Maxim Group LLC for these offerings?

Biodexa has engaged Maxim Group LLC as exclusive placement and inducement agent. The company will pay a cash fee equal to 8.0% of the aggregate gross proceeds from the sale of the securities, plus reimbursement of specified out-of-pocket and legal expenses under the placement agency agreement.

How will Biodexa register the resale of the new warrants and ADSs?

Biodexa entered a Registration Rights Agreement requiring it to file a registration statement for the resale of all warrants and ADSs issuable upon exercise. It will use commercially reasonable efforts to have this statement declared effective within specified deadlines following the closing of the transactions.

 

 

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549

 

FORM 6-K

 

REPORT OF FOREIGN PRIVATE ISSUER
PURSUANT TO RULE 13a-16 OR 15d-16 OF THE
SECURITIES EXCHANGE ACT OF 1934

 

For the month of June 2026
Commission File Number 001-37652

 

Biodexa Pharmaceuticals PLC

(Translation of registrant’s name into English)
1 Caspian Point,
Caspian Way,
Cardiff, CF10 4DQ, United Kingdom
(Address of principal executive offices)

 

Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F:

 

Form 20-F x Form 40-F ¨

 

Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(1): ¨

 

Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(7): ¨

 

 

 

  
 

 

EXPLANATORY NOTE

 

Registered Direct Offering

 

On June 29, 2026, Biodexa Pharmaceuticals PLC (the “Company”) entered into a securities purchase agreement (the “Purchase Agreement”) with an institutional investor (the “Investor”), pursuant to which the Company agreed to issue and sell, in a registered direct offering by the Company directly to the Investor (the “Registered Offering”), (i) an aggregate of 82,809 American Depositary Shares (“ADSs”) and (ii) an aggregate of 200,143 pre-funded warrants exercisable for ADSs (the “Registered Pre-Funded Warrants”).

 

Each ADS is being sold at an offering price of US$2.85, and each Registered Pre-Funded Warrant is being sold at an offering price of US$2.8499. Each ADS represents 500,000 ordinary shares, nominal value £0.000001 per share (the “Ordinary Shares”).

 

The Registered Pre-Funded Warrants are being sold, in lieu of ADSs, to the Investor such that the Investor’s purchase of ADSs in the Registered Offering would not otherwise result in such Investor, together with its affiliates and certain related parties, beneficially owning more than 4.99% or 9.99 (such amount to be determined at the option of the Investor upon issuance) of the Company’s outstanding Ordinary Shares immediately following the consummation of the Registered Offering. Each Registered Pre-Funded Warrant represents the right to purchase one ADS at an exercise price of $0.0001 per ADS. The Registered Pre-Funded Warrants will be exercisable immediately and may be exercised at any time until exercised in full.

 

The ADSs and Registered Pre-Funded Warrants are being offered pursuant to a prospectus supplement to be filed with the Securities and Exchange Commission (the “SEC”) in connection with a takedown from the Company’s registration statement on Form F-3 (File No. 333-290554), which was filed with the SEC on September 26, 2025 and declared effective on September 30, 2025 (the “Registration Statement”).

 

Additionally, pursuant to the terms of the Purchase Agreement, the Company will, upon receipt of shareholder approval (the “Shareholder Approval”), issue to the Investors warrants exercisable for an aggregate of 282,952 ADSs (the “Series M Warrants”), in a private placement transaction (the “First Private Placement”). The ADSs issuable upon exercise of the Series M Warrants are referred to herein as the “Series M Warrant ADSs.”

 

The Series M Warrants will be exercisable at an exercise price of US$2.85 per ADS, subject to adjustments for certain dilutive Company equity issuances. The Series M Warrants become exercisable upon receipt of Shareholder Approval. The Series M Warrants will expire five years from the date of the Shareholder Approval and may be exercised on a cashless basis. The Series M Warrants and the ADSs issuable upon the exercise of the Series M Warrants are not being registered under the Securities Act of 1933, as amended (the “Securities Act”), were not offered pursuant to the Registration Statement and were offered pursuant to the exemption provided in Section 4(a)(2) under the Securities Act, and Rule 506(b) promulgated thereunder.

 

The Investor (together with its affiliates) may not exercise the Series M Warrants if the Investor would beneficially own more than 4.99% or 9.99% (such amount to be determined at the option of the Investor upon issuance) of the number of Ordinary Shares outstanding immediately after giving effect to such exercise.

 

The Purchase Agreement contains customary representations, warranties and covenants of the Company and the Investor, and customary indemnification provisions for a transaction of this type. Pursuant to the terms of the Purchase Agreement, the Company has agreed to certain restrictions on subsequent equity sales and variable rate transactions, subject to certain exceptions.

 

Concurrent Private Placement

 

Additionally, on June 29, 2026, in a concurrent private placement transaction (the “Second Private Placement” and, together with the Registered Offering and the First Private Placement, the “Offerings”), the Company agreed to issue and sell to the Investor, (i) pre-funded warrants exercisable for an aggregate of 350,877 ADSs (the “Unregistered Pre-Funded Warrants,” and together with the Registered Pre-Funded Warrants, the “Pre-Funded Warrants”) and (ii) upon receipt of Shareholder Approval, warrants to purchase an aggregate of 701,754 ADSs (the “Series N Warrants,” and together with the Series M Warrants and the Pre-Funded Warrants, the “Warrants”). The ADSs issuable upon exercise of the Series N Warrants are referred to herein as the “Series N Warrant ADSs.” The ADSs issuable upon exercise of the Warrants are referred to herein as the “Warrant ADSs.”

 

  
 

 

Each Unregistered Pre-Funded Warrant is being sold at an offering price of US$2.8499. The Unregistered Pre-Funded Warrants are being sold, in lieu of ADSs, to the Investor such that the Investor’s purchase of ADSs in the would not otherwise result in such Investor, together with its affiliates and certain related parties, beneficially owning more than 4.99% or 9.99% (such amount to be determined at the option of the Investor upon issuance) of the Company’s outstanding Ordinary Shares immediately following the consummation of the Offerings. Each Unregistered Pre-Funded Warrant represents the right to purchase one ADS at an exercise price of $0.0001 per ADS. The Unregistered Pre-Funded Warrants will be exercisable immediately and may be exercised at any time until exercised in full.

 

The Series N Warrants will be exercisable at an exercise price of US$2.85 per ADS, subject to adjustments for certain dilutive Company equity issuances. The Series N Warrants become exercisable upon receipt of Shareholder Approval. The Series N Warrants will expire five years from the date of the Shareholder Approval and may be exercised on a cashless basis. The Series N Warrants and the ADSs issuable upon the exercise of the Series N Warrants are not being registered under the Securities Act, were not offered pursuant to the Registration Statement and were offered pursuant to the exemption provided in Section 4(a)(2) under the Securities Act, and Rule 506(b) promulgated thereunder.

 

The Investor (together with its affiliates) may not exercise the Series N Warrants if the Investor would beneficially own more than 4.99% or 9.99% (such amount to be determined at the option of the Investor upon issuance) of the number of Ordinary Shares outstanding immediately after giving effect to such exercise.

 

The Company entered into a registration rights agreement (the “Registration Rights Agreement”) with the Investor in which it agreed to file with the SEC a registration statement covering the resale of all of the Warrants and Warrant ADSs within fifteen calendar days after the closing date, to use commercially reasonable efforts to cause the registration statement to become effective by the 45th calendar day following the closing date (or, in the event of a “full review” by the SEC, the 75th calendar day).

 

Warrant Inducement

 

On June 29, 2026, the Company entered into warrant exercise inducement letter agreement (the “Inducement Letter”) with a holder of certain of the Company’s outstanding Series L warrants to purchase Ordinary Shares represented by ADSs (the “Existing Warrants”), pursuant to which such holder agreed to exercise Existing Warrants to purchase an aggregate of 609,756 ADSs at a reduced exercise price of $2.85 per ADS (the “Warrant Inducement”). In consideration therefor, the Company agreed, upon receipt of Shareholder Approval, to issue unregistered warrants to purchase an aggregate of 1,219,512 ADSs (the “Series O Warrants”), representing 200% of the ADSs issued upon exercise of the Existing Warrants. The Series O Warrants will have an exercise price of US$2.85 per ADS, will not be exercisable until Shareholder Approval is obtained and will have a term of five years from the date Shareholder Approval is obtained.

 

The aggregate gross proceeds to the Company from the Offerings and the Warrant Inducement are expected to be approximately $3.54 million, before deducting placement agent fees and related offering expenses. The Offerings and the Warrant Inducement are expected to close on or about July 1, 2026, subject to customary closing conditions.

 

In connection with the Offerings and the Warrant Inducement, the Company entered into a placement agency agreement (the “Placement Agent Agreement”) with Maxim Group LLC (“Maxim”), pursuant to which the Company engaged Maxim as the exclusive placement agent for the Offering. The Company agreed to pay Maxim a cash fee in an amount equal to 8.0% of the aggregate gross proceeds received by the Company from the sale of the securities at the closing and to reimburse Maxim for certain out-of-pocket expenses, including the reasonable fees and expenses of Maxim’s counsel, subject to the limits set forth in the Placement Agent Agreement.

 

  
 

 

The foregoing descriptions of the Purchase Agreement, the Warrants, the Inducement Letter, the Series O Warrants, the Placement Agent Agreement, and the Registration Rights Agreement are not complete and are qualified in their entirety by references to the full text of the forms of Purchase Agreement, Unregistered Pre-Funded Warrants, Registered Pre-Funded Warrants, Series M Warrants, Series N Warrants, the Inducement Letter, Series O Warrants, the Placement Agent Agreement, and the Registration Rights Agreement, which are filed as exhibits to this Report and are incorporated by reference herein.

 

This report on Form 6-K does not constitute an offer to sell any securities or a solicitation of an offer to buy any securities, nor shall there be any sale of any securities in any state or jurisdiction in which such an offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state or jurisdiction.

 

The information included under the headings “Registered Direct Offering,” “Concurrent Private Placement” and “Warrant Inducement” of this Report on Form 6-K, including Exhibits 4.1, 4.2, 4.3, 4.4, 4.5, 5.1, 5.2, 10.1, 10.2 and 10.3, shall be deemed to be incorporated by reference into the registration statements on Form S-8 (File No. 333-209365) and Form F-3 (File No. 333-290554) of the Company (including any prospectuses forming a part of such registration statements) and to be a part thereof from the date on which this report is filed, to the extent not superseded by documents or reports subsequently filed or furnished.

 

Other Events

 

On June 30, 2026, the Company issued a press release disclosing the material terms of the transactions contemplated by the Purchase Agreement and the Inducement Letter, a copy of which is furnished as Exhibit 99.1 and incorporated herein by reference.

 

The information in the attached Exhibit 99.1 is being furnished and shall not be deemed “filed” for the purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), or otherwise subject to the liabilities of that Section, nor shall it be deemed incorporated by reference in any filing made by the Company under the Securities Act of 1933, as amended, or the Exchange Act, except as otherwise set forth herein or as shall be expressly set forth by specific reference in such a filing.

 

Forward-Looking Statements

 

This report on Form 6-K contains forward-looking statements that involve risks and uncertainties, such as statements related to the anticipated closing of the Offerings and the Warrant Inducement, the amount of proceeds expected from the Offerings and the Warrant Inducement, the Company’s ability to obtain shareholder approval for the issuance of the Warrants and the exercise of the Warrants, and the expected filing and effectiveness of resale registration statements. The risks and uncertainties involved include the Company’s ability to satisfy certain conditions to closing on a timely basis or at all, market conditions, the Company’s ability to obtain required shareholder approval and other risks detailed from time to time in the Company’s periodic reports and other filings with the SEC. You are cautioned not to place undue reliance on forward-looking statements, which are based on the Company’s current expectations and assumptions and speak only as of the date of this report on Form 6-K. The Company does not intend to revise or update any forward-looking statement in this report on Form 6-K as a result of new information, future events or otherwise, except as required by law.

 

  
 

 

SUBMITTED HEREWITH

 

Attached to the Registrant’s Form 6-K filing for the month of June 2026, and incorporated by reference herein, is:

 

 Exhibit No. Description
   
4.1 Form of Series M Warrant.
   
4.2 Form of Series N Warrant.
   
4.3 Form of Series O Warrant
   
4.4 Form of Registered Pre-Funded Warrant
   
4.5 Form of Unregistered Pre-Funded Warrant
   
5.1 Opinion of Stephenson Hartwood LLP*
   
5.2 Opinion of Mintz, Levin, Cohn, Ferris, Glovsky & Popeo P.C.
   
10.1 Form of Securities Purchase Agreement, dated as of June 29, 2026, by and between Biodexa Pharmaceuticals PLC and the investors identified on the signature pages thereto.**
   
10.2 Placement Agency Agreement, dated as of June 29, 2026, by and between Biodexa Pharmaceuticals PLC and Maxim Group LLC.
   
10.3 Registration Rights Agreement, dated as of June 29, 2026, by and between Biodexa Pharmaceuticals PLC and the purchasers identified on the signature pages thereto.
   
10.4 Form of Warrant Inducement Agreement, dated as of June 29, 2026, by and between Biodexa Pharmaceuticals PLC and the holders identified on the signature pages thereto.
   
99.1 Press release dated June 30, 2026.
   
104 Cover Page Interactive Data File (formatted in Inline XBRL).

 

* To be filed by amendment.

 

** Non-material schedules and exhibits have been omitted pursuant to Item 601(a)(5) of Regulation S-K. The Company hereby undertakes to furnish supplemental copies of any of the omitted schedules and exhibits upon request by the SEC.

 

  
 

 

SIGNATURE

 

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

 

 

  Biodexa Pharmaceuticals PLC
     
     
Date: June 30, 2026 By: /s/ Stephen Stamp
    Stephen Stamp
    Chief Executive Officer
     

 

 

 

 

 

 

 

Exhibit 99.1

 

 

Biodexa Announces Pricing of $3.5 Million Registered Direct Offering & Concurrent Private Placement of Pre-Funded Warrants and Warrants

 

June 30, 2026

 

Biodexa Pharmaceuticals PLC, (Nasdaq: BDRX) (“Biodexa” or the “Company”), a clinical stage biopharmaceutical company developing a pipeline of innovative products for the treatment of diseases with unmet medical needs, today announced the pricing of a $0.8 million registered offering (the “Registered Offering”), a $1.0 million concurrent private placement (the “Private Offering”) and a $1.7 million warrant inducement (the “Warrant Inducement” and, together with the Registered Offering and the Private Offering, the “Offerings”) utilizing existing share capital authorities.

 

The Registered Offering consists of 282,952 American depositary shares (“ADSs”) (or pre-funded warrants in lieu thereof) at an offering price of $2.85 per ADS. The Private Offering consists of pre-funded warrants to purchase 350,877 ADSs at a combined offering price of $2.8499 per pre-funded warrant. In consideration for the immediate exercise of existing warrants (the “Existing Warrants”) for cash, the Company agreed to reduce the exercise price of the Existing Warrants to $2.85 and, subject to shareholder approval, issue new unregistered Series O warrants (“Series O Warrants”) to purchase an aggregate of 1,219,512 ADSs.

 

In addition, subject to shareholder approval, the investor will be issued (i) in connection with the Registered Offering, Series M warrants (“Series M Warrants”) to purchase up to 282,952 ADSs (the “Series M Warrant ADSs”), (ii) in connection with the Private Offering, Series N warrants (“Series N Warrants,” and together with the Series M Warrants and Series O Warrants, the “Warrants”) to purchase up to 701,754 ADSs (the “Series N Warrant ADSs”) and (iii) in connection with the Warrant Inducement, Series O warrants to purchase up to an aggregate of 1,219,512 ADSs (the “Series O Warrant ADSs,” and together with the Series M Warrant ADSs and Series N Warrant ADSs, the “Warrant ADSs”). The Warrants sold in the Offerings will be delivered and become exercisable without trigger upon receipt of shareholder approval to allot the Warrants, the Warrant ADSs and the ordinary shares underlying the Warrant ADSs (the “Warrant Shares”) offered in the Private Placement without triggering statutory preemptive rights under the laws of England and Wales. The Warrants each have an exercise price of $2.85 per ADS and are not exercisable until the Company obtains the shareholder approval. They will expire five years from the date such stockholder approval is obtained.

 

The Offerings are expected to close on or about July 1, 2026, subject to customary closing conditions. The aggregate gross proceeds to the Company, before deducting placement agent fees and other offering expenses, are expected to be approximately $3.5 million. The Company intends to use the net proceeds from this offering to fund its development programs, for working capital and for other general corporate purposes.

 

Maxim Group LLC is acting as the sole placement agent and warrant inducement agent for the Offerings.

 

The Registered Offering is being made pursuant to an effective shelf registration statement on Form F-3 (File No. 333-290554) previously filed with and subsequently declared effective by the U.S. Securities and Exchange Commission (“SEC”) on September 30, 2025. The Registered Offering is being made only by means of a prospectus supplement and accompanying prospectus that form a part of the effective shelf registration statement. A prospectus supplement relating to the ADSs and a portion of the pre-funded warrants to be issued in the Registered Offering will be filed by the Company with the SEC. When available, copies of the prospectus supplement relating to the Registered Offering, together with the accompanying prospectus, can be obtained at the SEC's website at www.sec.gov or by contacting Maxim Group LLC, at 300 Park Avenue, 16th Floor, New York, NY 10022, Attention: Syndicate Department, or via email at syndicate@maximgrp.com or by telephone at (212) 895-3745.

 

A portion of the pre-funded warrants and the Warrants described above were offered in a private placement under Section 4(a)(2) of the Securities Act of 1933, as amended (the “Act”) and Regulation D promulgated thereunder and, along with Warrant ADSs, have not been registered under the Act, or applicable state securities laws. Accordingly, the Warrants, pre-funded warrants offered in the private placement, underlying Warrant ADSs and ADSs issuable upon exercise of the pre-funded warrants offered in the private placement may not be offered or sold in the United States except pursuant to an effective registration statement or an applicable exemption from the registration requirements of the Act and such applicable state securities laws. Pursuant to a securities purchase agreement, the Company has agreed to file one or more registration statements with the SEC covering the resale of the ADSs issuable upon exercise of the pre-funded warrants and Warrants.

 

  
 

 

This press release shall not constitute an offer to sell or the solicitation of an offer to buy these securities, nor shall there be any sale of these securities in any state or other jurisdiction in which such offer, solicitation or sale would be unlawful prior to the registration or qualification under the securities laws of any such state or other jurisdiction.

 

About Biodexa Pharmaceuticals PLC

 

The Company’s lead development programs include eRapa, under development for Familial Adenomatous Polyposis and Non-Muscle Invasive Bladder Cancer, MTX240 under development for Gastrointestinal Stromal Tumors (GIST) and tolimidone, under development for the treatment of type 1 diabetes.

 

eRapa is a proprietary oral capsule formulation of rapamycin, also known as sirolimus. Rapamycin is an mTOR (mammalian Target Of Rapamycin) inhibitor. mTOR has been shown to have a significant role in the signalling pathway that regulates cellular metabolism, growth and proliferation and is activated during tumorigenesis.

 

MTX240 is a molecular glue, bringing two intracellular proteins, PDE3a and SLFN12, specifically co-expressed by GIST cancer cells, into close proximity to form a stable complex. This interaction stabilizes SLFN12, enabling it to drive RNase-mediated apoptosis in GIST cells through a mechanism independent of KIT signalling.

 

Tolimidone is an orally delivered, potent and selective inhibitor of Lyn kinase. Lyn is a member of the Src family of protein tyrosine kinases, which is mainly expressed in hematopoietic cells, in neural tissues, liver, and adipose tissue. Tolimidone demonstrates glycaemic control via insulin sensitization in animal models of diabetes and has the potential to become a first in class blood glucose modulating agent.

 

Biodexa’s headquarters and R&D facility is in Cardiff, UK. For more information visit www.biodexapharma.com.

 

Forward Looking Statements

 

Certain statements in this announcement may constitute “forward-looking statements” within the meaning of legislation in the United Kingdom and/or United States.  Such statements are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995 and are based on management’s belief or interpretation.  All statements contained in this announcement that do not relate to matters of historical fact should be considered forward-looking statements including, but not limited to, statements regarding the completion of the offering, the satisfaction of customary closing conditions related to the offering, the anticipated use of proceeds therefrom, and the exercise of the Existing Warrants prior to their expiration. In certain cases, forward-looking statements can be identified by the use of words such as “plans”, “expects” or “does not anticipate”, or “believes”, or variations of such words and phrases or statements that certain actions, events or results “may”, “could”, “would”, “might” or “will be taken”, “occur” or “be achieved.”  Forward-looking statements and information are subject to various known and unknown risks and uncertainties, many of which are beyond the ability of the Company to control or predict, that may cause their actual results, performance or achievements to be materially different from those expressed or implied thereby, and are developed based on assumptions about such risks, uncertainties and other factors set out herein.

 

Reference should be made to those documents that Biodexa shall file from time to time or announcements that may be made by Biodexa in accordance with the rules and regulations promulgated by the SEC, which contain and identify other important factors that could cause actual results to differ materially from those contained in any projections or forward-looking statements.  These forward-looking statements speak only as of the date of this announcement.  All subsequent written and oral forward-looking statements by or concerning Biodexa are expressly qualified in their entirety by the cautionary statements above.  Except as may be required under relevant laws in the United States, Biodexa does not undertake any obligation to publicly update or revise any forward-looking statements because of new information, future events or events otherwise arising.

 

  
 

 

For more information, please contact:

 


Biodexa Pharmaceuticals PLC

Stephen Stamp, CEO, CFO

Tel: +44 (0)29 20480 180

www.biodexapharma.com

534363131v.2

 

 

 

 

 

Filing Exhibits & Attachments

11 documents