BioAge Labs (NASDAQ: BIOA) Q1 2026 loss deepens amid R&D and pipeline push
Rhea-AI Filing Summary
BioAge Labs, Inc. reported first quarter 2026 results, highlighting pipeline progress and a larger operating loss as it invests in development. Collaboration revenue was $2.8 million versus $1.5 million a year earlier, driven by higher work under its Novartis collaboration.
Research and development expenses rose to $20.4 million and general and administrative expenses to $7.7 million, leading to a net loss of $22.3 million or $0.52 per share, compared with a $12.9 million loss in 2025. The company closed an upsized follow-on public offering with gross proceeds of about $132.3 million and ended March 31, 2026 with $384.9 million in cash, cash equivalents and marketable securities, which it expects to fund operations through 2029.
BioAge reported positive Phase 1 data for its oral NLRP3 inhibitor BGE-102, showing median 86% reductions in hsCRP at 60 mg and 120 mg once-daily doses and a favorable safety profile. It plans to start a Phase 2 cardiovascular risk study and a Phase 1b/2a diabetic macular edema trial for BGE-102 in mid-2026, while advancing APJ agonist programs toward an initial IND filing by year-end 2026.
Positive
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Negative
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8-K Event Classification
Key Figures
Key Terms
NLRP3 inhibitor medical
diabetic macular edema medical
Phase 1b/2a medical
APJ agonist medical
follow-on public offering financial
hsCRP medical
Earnings Snapshot
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
FORM 8-K
CURRENT REPORT
Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934
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Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:
Securities registered pursuant to Section 12(b) of the Act:
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Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§ 230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§ 240.12b-2 of this chapter).
Emerging growth company
If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act.
Item 2.02 Results of Operations and Financial Condition.
On May 8, 2026, BioAge Labs, Inc. (the “Company”) issued a press release announcing its financial results for the first quarter ended March 31, 2026. A copy of the press release is attached as Exhibit 99.1 to this Current Report on Form 8-K.
The information in this Item 2.02, including Exhibit 99.1 attached to this report, shall not be deemed to be “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), or otherwise subject to the liabilities of that section or Sections 11 and 12(a)(2) of the Securities Act of 1933, as amended (the “Securities Act”). The information contained in this Item 2.02 and in the accompanying Exhibit 99.1 shall not be incorporated by reference into any other filing under the Exchange Act or under the Securities Act, except as shall be expressly set forth by specific reference in such filing.
Item 9.01 Financial Statements and Exhibits.
(d) Exhibits
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Exhibit |
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Description |
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99.1 |
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Press release issued by BioAge Labs, Inc. dated May 8, 2026. |
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Cover Page Interactive Data File (embedded within the Inline XBRL document). |
SIGNATURES
Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.
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BIOAGE LABS, INC. |
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Date: |
May 8, 2026 |
By: |
/s/ Dov Goldstein |
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Dov Goldstein, M.D. |
Exhibit 99.1
BioAge Labs Reports First Quarter 2026 Financial Results and Provides Business Updates
Positive topline Phase 1 data for BGE-102, demonstrating potential best-in-class reductions among oral NLRP3 inhibitors in inflammatory biomarkers of cardiovascular risk
Phase 2 dose-ranging proof-of-concept trial of BGE-102 in cardiovascular risk planned to initiate in mid-2026, with data anticipated by end of year
Phase 1b/2a proof-of-concept trial of BGE-102 in diabetic macular edema (DME) planned to initiate in mid-2026, with data anticipated in mid-2027
Completed upsized follow-on public offering of $132.3 million
EMERYVILLE, Calif., May 8, 2026 (GLOBE NEWSWIRE) -- BioAge Labs, Inc. (NASDAQ: BIOA) ("BioAge” or, "the Company"), a clinical-stage biopharmaceutical company developing therapeutic product candidates for cardiometabolic diseases by targeting the biology of human aging, today provided business updates and reported its first quarter 2026 financial results.
“The positive topline Phase 1 data we reported for BGE-102 in April reinforce our conviction that we have a potential best-in-class NLRP3 inhibitor: a well-tolerated, once-daily oral therapy that could deliver the anti-inflammatory efficacy of injectables," said Kristen Fortney, Ph.D., CEO and co-founder of BioAge. "Our focus now is execution. We plan to initiate two BGE-102 proof-of-concept trials by mid-2026 — a Phase 2 dose-ranging trial in cardiovascular risk, and a Phase 1b/2a trial in diabetic macular edema — advancing BGE-102 as a potential 'pipeline in a pill' across cardiometabolic and ocular diseases. With the $132.3 million we raised in our upsized follow-on offering earlier this year, we have the capital to drive both programs through key milestones.”
First Quarter 2026 Business Highlights
NLRP3 inhibitor clinical development
BGE-102 indication expansion into ophthalmology
APJ agonist program advancement
Upsized follow-on public offering
Strategic partnerships and discovery platform
First Quarter 2026 Financial Results
Collaboration revenue was $2.8 million for the quarter ended March 31, 2026, compared to $1.5 million for the same period in 2025. The $1.3 million increase in collaboration revenue was due to increased full-time equivalent employee (FTE) effort under the Novartis collaboration agreement, resulting in higher revenue recognized based on progress toward satisfaction of the related performance obligation.
Research and development expenses were approximately $20.4 million for the quarter ended March 31, 2026, compared to $11.1 million for the same period in 2025. The $9.3 million increase in research and development expenses was primarily attributable to a $5.7 million increase in direct costs related to the BioAge’s BGE-102 program associated with the completion of the Phase 1 single ascending dose (SAD) / multiple ascending dose (MAD) clinical trial, preparation for the planned Phase 2 dose-ranging proof-of-concept trial evaluating BGE-102 in participants with elevated cardiovascular risk and planned Phase 1b/2a proof-of-concept trial in DME, each expected to initiate in mid-2026, and drug-product manufacturing. Additionally contributing to the increase was a $3.6 million increase in direct costs for other programs, which was primarily related to discovery and development activities related to BioAge’s novel apelin receptor APJ agonist programs, and a $0.8 million increase in allocated facility and other expenses primarily driven by an increase in non-program specific consulting fees. These increases were partially offset by a $0.8 million reduction in azelaprag direct costs following termination of development in January 2025.
General and administrative expenses were $7.7 million for the quarter ended March 31, 2026, compared to $6.8 million for the same period in 2025. The $0.9 million increase was primarily attributable to a $0.6 million increase in personnel-related expenses, largely due to an increase in stock-based compensation expense associated with new option grants issued to employees, executives, board members, and advisors, and a $0.4 million increase in legal fees, partially offset by a $0.1 million decrease in consulting expenses.
Net loss was $22.3 million for the quarter ended March 31, 2026, or $0.52 per weighted-average common share outstanding, basic and diluted, compared to a net loss of $12.9 million, or $0.36 per weighted-average common share outstanding, basic and diluted, for the same period in 2025.
As of March 31, 2026, BioAge had approximately $384.9 million in cash, cash equivalents, and marketable securities. Based on its current operating plan, BioAge estimates that existing cash and cash equivalents will be sufficient to fund operations and capital expenses through 2029.
About BioAge Labs, Inc.
BioAge is a clinical-stage biopharmaceutical company developing therapeutic product candidates for cardiometabolic diseases by targeting the biology of human aging. The Company's lead product candidate, BGE-102, is a potent, orally available, brain-penetrant small-molecule NLRP3 inhibitor being developed for cardiovascular risk and retinal diseases including diabetic macular edema. BGE-102 has completed a Phase 1 SAD/MAD trial demonstrating a well-tolerated profile and potential best-in-class reductions in hsCRP and other inflammatory biomarkers in participants with obesity and elevated inflammation. Phase 2 cardiovascular risk proof-of-concept data are anticipated by end of year 2026, and Phase 1b/2a diabetic macular edema proof-of-concept data are anticipated in mid-2027. The Company is also developing long-acting injectable and oral small molecule APJ agonists for obesity. BioAge’s additional preclinical programs, which leverage insights from the Company’s proprietary discovery platform built on human longevity data, address key pathways involved in metabolic aging.
Forward-looking statements
This press release contains “forward-looking statements” within the meaning of, and made pursuant to the safe harbor provisions of, the Private Securities Litigation Reform Act of 1995. In some cases, you can identify forward-looking statements by terms such as “aim,” “may,” “will,” “should,” “expect,” “forecast,” “plan,” “anticipate,” “could,” “intend,” “target,” “project,” “contemplate,” “believe,” “estimate,” “predict,” “potential” or “continue” or the negative of these terms or other similar expressions, although not all forward-looking statements contain these words. All statements other than statements of historical fact contained in this press release, including without limitation statements regarding our plans to develop and commercialize our product candidates, including BGE-102 and our APJ programs, the potential for BGE-102 as a treatment for atherosclerotic cardiovascular disease risk reduction and diabetic macular edema, the expected timeline for data readouts from our ongoing Phase 1 clinical trial, the expected timing and results of our ongoing or planned preclinical studies and clinical trials, risks associated with clinical trials, including our ability to adequately manage clinical activities for BGE-102 and our APJ programs, unexpected concerns that may arise from additional data or analysis obtained during clinical trials, the timing of and our ability to obtain and maintain
regulatory approvals, the clinical utility of our future product candidates, our commercialization, marketing and manufacturing capabilities and strategy, our expectations about the willingness of healthcare professionals to use our product candidates, the sufficiency of our cash, cash equivalents and marketable securities, general economic conditions, the impact of industry and market conditions on our operations, including fluctuating interest rates and inflation, increased volatility in the debt and equity markets, legislative or regulatory healthcare reforms in the United States, significant political, trade or regulatory developments, including tariffs, federal government shutdowns, or shifting priorities within the U.S. Food and Drug Administration, cybersecurity incidents, and global regional conflicts, and the plans and objectives of management for future operations and capital expenditures are forward-looking statements.
The forward-looking statements in this press release are only predictions and are based largely on our current expectations and projections about future events and financial trends that we believe may affect our business, financial condition and results of operations. These forward-looking statements speak only as of the date of this press release and are subject to a number of known and unknown risks, uncertainties and assumptions, including those described under the headings “Risk Factors” and “Management’s Discussion and Analysis of Financial Condition and Results of Operations” included in BioAge’s Quarterly Report on Form 10-Q filed with the U.S. Securities and Exchange Commission (SEC) on May 8, 2026, and BioAge’s other filings with the SEC filed from time to time.
Because forward-looking statements are inherently subject to risks and uncertainties, some of which cannot be predicted or quantified and some of which are beyond our control, you should not rely on these forward-looking statements as predictions of future events. The events and circumstances reflected in our forward-looking statements may not be achieved or occur and actual results could differ materially from those projected in the forward-looking statements. Moreover, we operate in an evolving environment. New risk factors and uncertainties may emerge from time to time, and it is not possible for management to predict all risk factors and uncertainties. BioAge undertakes no obligation to publicly update any forward-looking statement, whether written or oral, that may be made from time to time, whether as a result of new information, future developments or otherwise.
Contacts
PR: Chris Patil, media@bioagelabs.com
IR: Dov Goldstein, ir@bioagelabs.com
Partnering: partnering@bioagelabs.com
Web: https://bioagelabs.com
BIOAGE LABS, INC.
Unaudited Condensed Consolidated Statements of Operations and Comprehensive Loss
(in thousands, except share and per share information)
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Three Months Ended |
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March 31, |
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2026 |
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2025 |
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Collaboration revenue |
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$ |
2,772 |
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$ |
1,451 |
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Operating expenses: |
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Research and development |
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$ |
20,410 |
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$ |
11,109 |
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General and administrative |
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7,737 |
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6,788 |
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Total operating expenses |
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28,147 |
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17,897 |
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Loss from operations |
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(25,375 |
) |
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(16,446 |
) |
Other income (expense) |
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Interest expense |
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(39 |
) |
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(255 |
) |
Interest and other income (expense), net |
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3,268 |
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3,714 |
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Gain (loss) from changes in fair value of warrants |
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(107 |
) |
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59 |
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Total other income (expense), net |
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3,122 |
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3,518 |
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Net loss |
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$ |
(22,253 |
) |
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$ |
(12,928 |
) |
Net loss per share attributable to common stockholders, basic and diluted |
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$ |
(0.52 |
) |
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$ |
(0.36 |
) |
Weighted-average common shares outstanding, basic and diluted |
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42,480,488 |
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35,850,037 |
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Comprehensive loss: |
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Net loss |
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(22,253 |
) |
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(12,928 |
) |
Other comprehensive income (loss): |
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Unrealized holding gains (losses) on available-for-sale investments |
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(178 |
) |
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29 |
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Foreign currency translation adjustment |
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(27 |
) |
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(10 |
) |
Total other comprehensive income (loss): |
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(205 |
) |
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19 |
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Total comprehensive loss |
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$ |
(22,458 |
) |
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$ |
(12,909 |
) |
BIOAGE LABS, INC.
Unaudited Condensed Consolidated Balance Sheets
(in thousands, except share and per share information)
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March 31, |
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December 31, |
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2026 |
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2025 |
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Assets |
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Current Assets: |
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Cash and cash equivalents |
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$ |
241,777 |
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$ |
188,888 |
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Marketable securities, current |
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141,417 |
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92,210 |
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Accounts receivable |
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|
709 |
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769 |
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Prepaid expenses and other current assets |
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7,957 |
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4,926 |
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Total current assets |
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391,860 |
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|
286,793 |
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Investments |
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100 |
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|
|
100 |
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Marketable securities |
|
|
1,680 |
|
|
|
4,032 |
|
Property and equipment, net |
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1,115 |
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|
963 |
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Operating lease right-of-use assets |
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2,684 |
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2,785 |
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Other assets |
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215 |
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216 |
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Total assets |
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$ |
397,654 |
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$ |
294,889 |
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Liabilities |
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Current Liabilities: |
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Accounts payable |
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$ |
3,066 |
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$ |
2,674 |
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Accrued expenses and other current liabilities |
|
|
4,765 |
|
|
|
8,480 |
|
Current portion of term loan |
|
|
1,159 |
|
|
|
2,648 |
|
Operating lease liabilities, current |
|
|
646 |
|
|
|
582 |
|
Deferred revenue |
|
|
6,191 |
|
|
|
5,754 |
|
Total current liabilities |
|
|
15,827 |
|
|
|
20,138 |
|
Warrant liability |
|
|
477 |
|
|
|
370 |
|
Operating lease liabilities |
|
|
2,229 |
|
|
|
2,330 |
|
Total liabilities |
|
|
18,533 |
|
|
|
22,838 |
|
Commitments and Contingencies (Note 7) |
|
|
|
|
|
|
||
Stockholders’ Equity |
|
|
|
|
|
|
||
Preferred stock, $0.00001 par value; 10,000,000 shares authorized as of |
|
|
— |
|
|
|
— |
|
Common stock, $0.00001 par value; 500,000,000 shares authorized as of |
|
|
— |
|
|
|
— |
|
Additional paid-in-capital |
|
|
734,717 |
|
|
|
605,189 |
|
Accumulated other comprehensive income |
|
|
73 |
|
|
|
278 |
|
Accumulated deficit |
|
|
(355,669 |
) |
|
|
(333,416 |
) |
Total stockholders’ equity |
|
|
379,121 |
|
|
|
272,051 |
|
Total liabilities and stockholders’ equity |
|
$ |
397,654 |
|
|
$ |
294,889 |
|
FAQ
How did BioAge Labs (BIOA) perform financially in Q1 2026?
BioAge reported a Q1 2026 net loss of $22.3 million, or $0.52 per share. Collaboration revenue rose to $2.8 million from $1.5 million in 2025, while higher R&D and G&A spending drove the larger loss.
What were BioAge Labs (BIOA) research and development expenses in Q1 2026?
Research and development expenses were $20.4 million in Q1 2026, up from $11.1 million a year earlier. The increase mainly reflected higher spending on the BGE-102 program, including the completed Phase 1 trial and preparations for upcoming proof-of-concept studies.
How much cash does BioAge Labs (BIOA) have after its follow-on offering?
As of March 31, 2026, BioAge held about $384.9 million in cash, cash equivalents, and marketable securities. This includes proceeds from its upsized follow-on public offering of roughly $132.3 million, which the company believes can fund operations and capital needs through 2029.
What were the key clinical results for BGE-102 reported by BioAge Labs (BIOA)?
BioAge reported positive Phase 1 data for BGE-102, its oral NLRP3 inhibitor, with median 86% reductions in hsCRP at 60 mg and 120 mg once-daily dosing. Most treated participants reached hsCRP levels below 2 mg/L, and the drug was well tolerated with only mild to moderate adverse events.
What clinical trials is BioAge Labs (BIOA) planning for BGE-102?
BioAge plans a Phase 2 dose-ranging cardiovascular risk trial and a Phase 1b/2a diabetic macular edema trial for BGE-102, both expected to start in mid-2026. The company anticipates cardiovascular proof-of-concept data by late 2026 and diabetic macular edema data in mid-2027.
What is BioAge Labs’ (BIOA) strategy for its APJ agonist programs?
BioAge is advancing oral and injectable APJ agonist candidates for obesity and related metabolic indications. The company is progressing a novel APJ agonist antibody under an option agreement with JiKang Therapeutics and intends to file its first APJ-related IND by year-end 2026.