[SCHEDULE 13G] BIOLIFE SOLUTIONS INC Passive Investment Disclosure (>5%)

Rhea-AI Filing Summary

BioLife Solutions Inc. ownership update: Casdin Capital, LLC and related entities report shared beneficial ownership of 4,757,165 shares of Common Stock, representing 9.7% of the class as reported on 06/04/2026. The reported shares are held by advisory clients, including Casdin Partners Master Fund, L.P., and the filing disclaims direct sole voting or dispositive power.

Key Figures

Filing date: 06/04/2026 Shares beneficially owned: 4,757,165 shares Percent of class: 9.7% +2 more

5 metrics

Filing date 06/04/2026 Schedule 13G signature date

Shares beneficially owned 4,757,165 shares Held by Casdin reporting persons/advisory clients

Percent of class 9.7% Percent of Common Stock class reported

CUSIP 09062W204 Common Stock CUSIP listed in filing

Sole voting/dispositive power 0 shares No sole voting or dispositive power reported

Key Terms

Schedule 13G, beneficial ownership, shared dispositive power, Joint Filing Agreement

4 terms

Schedule 13G regulatory

"Item 1. (a) Name of issuer: BIOLIFE SOLUTIONS INC"

A Schedule 13G is a formal document that investors file with the government when they acquire a large ownership stake in a company, usually for investment purposes rather than control. It helps keep the public informed about who owns significant parts of a company's shares, which can influence how the company is managed and how investors make decisions. Filing this schedule is important for transparency and understanding the ownership landscape of publicly traded companies.

beneficial ownership financial

"Item 4. (a) Amount beneficially owned: Casdin Capital, LLC - 4,757,165"

Beneficial ownership means the person or entity that actually enjoys the benefits of owning shares or other assets — such as receiving dividends, voting rights, or price gains — even if the legal title is held in another name. For investors it matters because knowing who truly controls and profits from a company reveals who can influence decisions, exposes potential conflicts of interest or hidden concentration of power, and affects transparency and risk in the stock.

shared dispositive power regulatory

"Item 4. (iv) Shared power to dispose: Casdin Capital, LLC - 4,757,165"

Joint Filing Agreement legal

"Exhibit A - Joint Filing Agreement"

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SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13G

UNDER THE SECURITIES EXCHANGE ACT OF 1934

BIOLIFE SOLUTIONS INC

(Name of Issuer)

Common Stock, par value $0.001 per share

(Title of Class of Securities)

09062W204

(CUSIP Number)

06/04/2026

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

Rule 13d-1(b)

Rule 13d-1(c)

Rule 13d-1(d)

schemaVersion:

SCHEDULE 13G

CUSIP Number(s): 09062W204

1

Names of Reporting Persons

Casdin Capital, LLC

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 4,757,165.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 4,757,165.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

4,757,165.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

9.7 %

12

Type of Reporting Person (See Instructions)

IA

SCHEDULE 13G

CUSIP Number(s): 09062W204

1

Names of Reporting Persons

Casdin Partners Master Fund, L.P.

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

CAYMAN ISLANDS

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 4,757,165.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 4,757,165.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

4,757,165.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

9.7 %

12

Type of Reporting Person (See Instructions)

PN

SCHEDULE 13G

CUSIP Number(s): 09062W204

1

Names of Reporting Persons

Casdin Partners GP, LLC

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 4,757,165.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 4,757,165.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

4,757,165.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

9.7 %

12

Type of Reporting Person (See Instructions)

OO

SCHEDULE 13G

CUSIP Number(s): 09062W204

1

Names of Reporting Persons

Eli Casdin

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

UNITED STATES

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 4,757,165.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 4,757,165.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

4,757,165.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

9.7 %

12

Type of Reporting Person (See Instructions)

IN

SCHEDULE 13G

Item 1.
(a)	Name of issuer: BIOLIFE SOLUTIONS INC
(b)	Address of issuer's principal executive offices: 3303 Monte Villa Parkway, Suite 310, Bothell, WA 98021
Item 2.
(a)	Name of person filing: Casdin Capital, LLC Casdin Partners Master Fund, L.P. Casdin Partners GP, LLC Eli Casdin
(b)	Address or principal business office or, if none, residence: Casdin Capital, LLC 1350 Avenue of the Americas, Suite 2600 New York, New York Casdin Partners Master Fund, L.P. 1350 Avenue of the Americas, Suite 2600 New York, New York Casdin Partners GP, LLC 1350 Avenue of the Americas, Suite 2600 New York, New York Eli Casdin 1350 Avenue of the Americas, Suite 2600 New York, New York
(c)	Citizenship: Casdin Capital, LLC - Delaware Casdin Partners Master Fund, L.P. - Cayman Islands Casdin Partners GP, LLC - Delaware Eli Casdin - United States
(d)	Title of class of securities: Common Stock, par value $0.001 per share
(e)	CUSIP Number(s): 09062W204
Item 3.	If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)	Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)	Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)	Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)	Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)	An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)	An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)	A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)	A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)	A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)	A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J), please specify the type of institution:
(k)	Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.	Ownership
(a)	Amount beneficially owned: Casdin Capital, LLC - 4,757,165 Casdin Partners Master Fund, L.P. - 4,757,165 Casdin Partners GP, LLC - 4,757,165 Eli Casdin - 4,757,165
(b)	Percent of class: Casdin Capital, LLC - 9.7% Casdin Partners Master Fund, L.P. - 9.7% Casdin Partners GP, LLC - 9.7% Eli Casdin - 9.7%
(c)	Number of shares as to which the person has:
	(i) Sole power to vote or to direct the vote: Casdin Capital, LLC - 0 Casdin Partners Master Fund, L.P. - 0 Casdin Partners GP, LLC - 0 Eli Casdin - 0
	(ii) Shared power to vote or to direct the vote: Casdin Capital, LLC - 4,757,165 Casdin Partners Master Fund, L.P. - 4,757,165 Casdin Partners GP, LLC - 4,757,165 Eli Casdin - 4,757,165
	(iii) Sole power to dispose or to direct the disposition of: Casdin Capital, LLC - 0 Casdin Partners Master Fund, L.P. - 0 Casdin Partners GP, LLC - 0 Eli Casdin - 0
	(iv) Shared power to dispose or to direct the disposition of: Casdin Capital, LLC - 4,757,165 Casdin Partners Master Fund, L.P. - 4,757,165 Casdin Partners GP, LLC - 4,757,165 Eli Casdin - 4,757,165
Item 5.	Ownership of 5 Percent or Less of a Class.
	Not Applicable
Item 6.	Ownership of more than 5 Percent on Behalf of Another Person.
	If any other person is known to have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, such securities, a statement to that effect should be included in response to this item and, if such interest relates to more than 5 percent of the class, such person should be identified. A listing of the shareholders of an investment company registered under the Investment Company Act of 1940 or the beneficiaries of employee benefit plan, pension fund or endowment fund is not required. All of the securities reported in this Schedule 13G are directly owned by advisory clients of Casdin Capital, LLC. None of those advisory clients, other than Casdin Partners Master Fund, L.P., may be deemed to beneficially own more than 5% of the Common Stock, par value $0.001 per share.
Item 7.	Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
	Not Applicable
Item 8.	Identification and Classification of Members of the Group.
	Not Applicable
Item 9.	Notice of Dissolution of Group.
	Not Applicable

Item 10.

Certifications:

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

Casdin Capital, LLC

Signature:	/s/ Eli Casdin
Name/Title:	Eli Casdin, Managing Member
Date:	06/04/2026

Casdin Partners Master Fund, L.P.

Signature:	s/ Eli Casdin
Name/Title:	Eli Casdin, Managing Member of its General Partner
Date:	06/04/2026

Casdin Partners GP, LLC

Signature:	/s/ Eli Casdin
Name/Title:	Eli Casdin, Managing Member
Date:	06/04/2026

Eli Casdin

Signature:	/s/ Eli Casdin
Name/Title:	Eli Casdin
Date:	06/04/2026

Comments accompanying signature: * Each Reporting Person disclaims beneficial ownership of the reported securities except to the extent of his, her or its pecuniary interest therein, and this report shall not be deemed an admission that such Reporting Person is the beneficial owner of the securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose. To the extent that "ownership of 5 percent or less of a class" was indicated in Item 5, such response only applies to the Reporting Person(s) that indicated elsewhere herein that it beneficially owns five percent (5%) or less of the class.

Exhibit Information

Exhibit A - Joint Filing Agreement

FAQ

What stake does Casdin report in BIOLIFE SOLUTIONS INC (BLFS)?

Casdin reports shared beneficial ownership of 4,757,165 shares, equal to 9.7% of the class as of 06/04/2026. The shares are held by advisory clients including Casdin Partners Master Fund, L.P.

Which Casdin entities are named in the BLFS Schedule 13G filing?

The filing lists Casdin Capital, LLC, Casdin Partners Master Fund, L.P., Casdin Partners GP, LLC, and Eli Casdin as reporting persons, all at the same principal office in New York.

Does Casdin claim voting or dispositive control over the reported BLFS shares?

The filing shows 0 shares with sole voting or dispositive power and 4,757,165 shares with shared voting and dispositive power. Signatures include an ownership disclaimer by the reporting persons.

Are the reported BLFS shares held directly by Casdin or its clients?

The filing states the securities are directly owned by advisory clients of Casdin Capital, LLC, with Casdin Partners Master Fund, L.P. identified among those clients; other advisory clients do not exceed 5% individually.