BlossomHill Therapeutics, Inc. (BLSM) is the subject of a Schedule 13G reporting that Perceptive Advisors LLC, Joseph Edelman and Perceptive Life Sciences Master Fund, Ltd. collectively report beneficial ownership of 1,808,533 shares of BlossomHill common stock. The filing states this represents 5.9% of the 30,643,660 shares of common stock outstanding, as referenced in BlossomHill’s prospectus filed on August 7, 2026. The Master Fund directly holds the 1,808,533 shares, while Perceptive Advisors, as investment manager, and Mr. Edelman, as managing member of Perceptive Advisors, may be deemed to beneficially own these shares, all with shared voting and dispositive power.
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Key Figures
Shares beneficially owned:1,808,533 sharesPercent of class owned:5.9%Shares outstanding:30,643,660 shares+2 more
5 metrics
Shares beneficially owned1,808,533 sharesCommon Stock of BlossomHill Therapeutics beneficially owned by each Reporting Person
Percent of class owned5.9%Ownership percentage of BlossomHill common stock reported by each Reporting Person
Shares outstanding30,643,660 sharesBlossomHill common stock outstanding as reported in prospectus filed August 7, 2026
Shared voting power1,808,533 sharesShares over which each Reporting Person has shared power to vote or direct the vote
Shared dispositive power1,808,533 sharesShares over which each Reporting Person has shared power to dispose or direct disposition
"Perceptive Advisors LLC, Joseph Edelman and the Master Fund file this Schedule 13G"
A Schedule 13G is a formal document that investors file with the government when they acquire a large ownership stake in a company, usually for investment purposes rather than control. It helps keep the public informed about who owns significant parts of a company's shares, which can influence how the company is managed and how investors make decisions. Filing this schedule is important for transparency and understanding the ownership landscape of publicly traded companies.
beneficially ownfinancial
"Perceptive Advisors serves as the investment manager to the Master Fund and may be deemed to beneficially own such shares"
Beneficially own means having the economic rights and risks of a security—such as the right to receive dividends, sell the shares, or profit from price changes—whether or not your name appears on the official share register. Think of it like renting a car: you use it and reap the benefits even if the title lists someone else. Investors care because beneficial ownership determines who truly controls value, must be disclosed under securities rules, and can signal potential influence or trading activity that affects a stock’s price.
shared voting powerfinancial
"Shared Voting Power 1,808,533.00"
Shared voting power occurs when two or more parties jointly have the right to vote or decide how a block of company shares is cast, like co-owners who must agree before moving a piece of furniture. Investors care because who controls voting rights affects board elections, major corporate decisions and takeover outcomes, and shared control can alter regulatory disclosures and the practical influence any holder has over a company’s direction and value.
shared dispositive powerfinancial
"Shared Dispositive Power 1,808,533.00"
dispositive powerfinancial
"Sole Dispositive Power 0.00 8 | Shared Dispositive Power 1,808,533.00"
Dispositive power is the authority to decide the final outcome of an asset, legal claim, contract, or corporate action — in effect the power to dispose of or resolve something. For investors it matters because whoever holds that authority can determine who gets paid, who controls an asset or vote, and how risks and returns are allocated; think of it like holding the key that lets you lock in the winner or loser in a deal.
FAQ
AI-generated questions and answers. How Rhea-AI works. Not financial advice.
What percentage of BlossomHill Therapeutics (BLSM) shares does Perceptive report owning?
Perceptive-associated entities report beneficial ownership of 5.9% of BlossomHill Therapeutics common stock. This percentage is based on 30,643,660 shares outstanding, as disclosed in BlossomHill’s August 7, 2026 prospectus filed pursuant to Rule 424(b)(4).
How many BlossomHill Therapeutics (BLSM) shares are held by Perceptive Life Sciences Master Fund?
Perceptive Life Sciences Master Fund, Ltd. directly holds 1,808,533 shares of BlossomHill Therapeutics common stock. Perceptive Advisors LLC, as investment manager, and Joseph Edelman, as managing member, may be deemed to beneficially own these shares with shared voting and dispositive power.
Who are the reporting persons in the BlossomHill Therapeutics (BLSM) Schedule 13G?
The Schedule 13G lists three reporting persons: Perceptive Advisors LLC, Joseph Edelman, and Perceptive Life Sciences Master Fund, Ltd.. All three report beneficial ownership of the same 1,808,533 shares of BlossomHill common stock, representing 5.9% of the outstanding class.
What voting power do Perceptive entities have over BlossomHill Therapeutics (BLSM) shares?
Perceptive Advisors, Joseph Edelman, and the Master Fund each report 0 shares with sole voting power and 1,808,533 shares with shared voting power. They also report shared dispositive power over the same 1,808,533 shares of BlossomHill common stock.
On what share count is the 5.9% ownership in BlossomHill Therapeutics (BLSM) based?
The reported 5.9% ownership is based on 30,643,660 shares of BlossomHill common stock outstanding. This outstanding share figure comes from BlossomHill’s prospectus filed pursuant to Rule 424(b)(4) on August 7, 2026.
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
SCHEDULE 13G
UNDER THE SECURITIES EXCHANGE ACT OF 1934
BlossomHill Therapeutics, Inc.
(Name of Issuer)
Common Stock, par value $0.0001
(Title of Class of Securities)
095130100
(CUSIP Number)
08/07/2026
(Date of Event Which Requires Filing of this Statement)
Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
Rule 13d-1(b)
Rule 13d-1(c)
Rule 13d-1(d)
schemaVersion:
SCHEDULE 13G
CUSIP Number(s):
095130100
1
Names of Reporting Persons
Perceptive Advisors LLC
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
DELAWARE
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
1,808,533.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
1,808,533.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
1,808,533.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
5.9 %
12
Type of Reporting Person (See Instructions)
IA
SCHEDULE 13G
CUSIP Number(s):
095130100
1
Names of Reporting Persons
Joseph Edelman
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
UNITED STATES
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
1,808,533.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
1,808,533.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
1,808,533.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
5.9 %
12
Type of Reporting Person (See Instructions)
IN
SCHEDULE 13G
CUSIP Number(s):
095130100
1
Names of Reporting Persons
Perceptive Life Sciences Master Fund, Ltd.
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
CAYMAN ISLANDS
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
1,808,533.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
1,808,533.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
1,808,533.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
5.9 %
12
Type of Reporting Person (See Instructions)
CO
SCHEDULE 13G
Item 1.
(a)
Name of issuer:
BlossomHill Therapeutics, Inc.
(b)
Address of issuer's principal executive offices:
10255 Science Center Drive, Suite 200, San Diego, California 92121
Item 2.
(a)
Name of person filing:
The names of the persons filing this report (collectively, the "Reporting Persons") with respect to the Common Stock, par value $0.0001 (the "Common Stock") of BlossomHill Therapeutics, Inc. (the "Issuer") are:
(i) Perceptive Advisors LLC ("Perceptive Advisors")
(ii) Joseph Edelman ("Mr. Edelman")
(iii) Perceptive Life Sciences Master Fund, Ltd. (the "Master Fund")
(b)
Address or principal business office or, if none, residence:
The address of the principal business office of each of the Reporting Persons is:
51 Astor Place, 10th Floor, New York, NY 10003
(c)
Citizenship:
Perceptive Advisors is a Delaware limited liability company.
Mr. Edelman is a United States citizen.
The Master Fund is a Cayman Islands corporation.
(d)
Title of class of securities:
Common Stock, par value $0.0001
(e)
CUSIP Number(s):
095130100
Item 3.
If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)
Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)
Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)
Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)
Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)
An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)
An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)
A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)
A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)
A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)
A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J),
please specify the type of institution:
(k)
Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.
Ownership
(a)
Amount beneficially owned:
The information required by this item with respect to each Reporting Person is set forth in Rows 5 through 9 and 11 of the cover pages to this Schedule 13G. The ownership percentages reported are based on 30,643,660 shares of Common Stock outstanding, as reported by the Issuer in its prospectus filed pursuant to Rule 424(b)(4) with the Securities and Exchange Commission on August 7, 2026.
Neither Perceptive Advisors nor Mr. Edelman directly holds any shares of Common Stock. The Master Fund directly holds 1,808,533 shares of Common Stock. Perceptive Advisors serves as the investment manager to the Master Fund and may be deemed to beneficially own such shares. Mr. Edelman is the managing member of Perceptive Advisors and may be deemed to beneficially own such shares.
(b)
Percent of class:
Perceptive Advisors: 5.9%
Mr. Edelman: 5.9%
Master Fund: 5.9%
(c)
Number of shares as to which the person has:
(i) Sole power to vote or to direct the vote:
Perceptive Advisors: 0
Mr. Edelman: 0
Master Fund: 0
(ii) Shared power to vote or to direct the vote:
Perceptive Advisors: 1,808,533
Mr. Edelman: 1,808,533
Master Fund: 1,808,533
(iii) Sole power to dispose or to direct the disposition of:
Perceptive Advisors: 0
Mr. Edelman: 0
Master Fund: 0
(iv) Shared power to dispose or to direct the disposition of:
Perceptive Advisors: 1,808,533
Mr. Edelman: 1,808,533
Master Fund: 1,808,533
Item 5.
Ownership of 5 Percent or Less of a Class.
Not Applicable
Item 6.
Ownership of more than 5 Percent on Behalf of Another Person.
Not Applicable
Item 7.
Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
Not Applicable
Item 8.
Identification and Classification of Members of the Group.
Not Applicable
Item 9.
Notice of Dissolution of Group.
Not Applicable
Item 10.
Certifications:
By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11.
SIGNATURE
After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.