Indicate by check mark whether the registrant files or will file annual
reports under cover of Form 20-F or Form 40-F:
On March 11, 2026, Biophytis S.A. issued a press release announcing
completion of over € 2.0 million capital increase and the repayment of all variable price convertible debt. A copy of the press release
is attached as Exhibit 99.1 to this Form 6-K.
Pursuant to the requirements of the Securities Exchange Act of 1934,
the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.
Exhibit 99.1

BIOPHYTIS
ANNOUNCES COMPLETION
OF
OVER €2.0 MILLION CAPITAL INCREASE AND THE
REPAYMENT
OF ALL VARIABLE PRICE CONVERTIBLE DEBT
| 1. | Capital
increase of a total amount of €2,015,000 in gross proceeds through the issuance of 30,957,144
new shares, 27,397,060 pre-funded warrants and 87,531,306 warrants |
| 2. | Investors
include two healthcare-focused U.S. based institutions: Funds managed / affiliated with Alumni
Capital Management LLC and Bigger Capital |
| 3. | Hexagon
Capital Fund, the holder of the company €2,000,000 credit line is also investing €300,000 |
| 4. | All
variable price convertible debt held by Atlas Capital (for €1,025,000) to be repaid
in cash out of proceeds |
| 5. | €1,224,787
cash pay debt held by Kreos Capital to carry no interest or coupon prior to June 1st,
2026, and maturity pushed out to July 1st, 2029 |
| 6. | All
remaining proceeds to be directed to clinical development in sarcopenia and obesity |
NOT TO BE DIRECTLY OR INDIRECTLY DISTRIBUTED
IN UNITED STATES OF AMERICA, CANADA, AUSTRALIA, JAPAN OR SOUTH AFRICA. THIS PRESS RELEASE IS FOR INFORMATION PURPOSES AND DOES NOT CONSTITUTE
AN OFFER TO SALE OR A SOLICITATION OF AN OFFER TO PURCHASE SECURITIES IN ANY JURISDICTION.
Paris (France) and Cambridge (Massachusetts,
United States), March 11, 2026 at 7.30 AM (CET) – Biophytis SA (Euronext Growth Paris : ALBPS), (“Biophytis”
or the “Company”), a pioneer in the development of transformative therapies impacting longevity, today announces
the completion of a capital increase trough the issue of new shares each accompanied by a share subscription warrant, with the removal
of the preferential subscription rights of the Company’s existing shareholders in favor of several institutional investors, for
a total gross amount of €2,015,000 (the “Issue”). This capital increase was subscribed by a limited number
of investors including Alumni Capital for €1,250,000 and Hexagon Capital Fund for €300,000.
Stanislas Veillet, CEO of Biophytis said: “Biophytis
is now positioned at the intersection of three global trends: demographic aging, obesity epidemic and the revolution in biotechnologies
applied in longevity. This fundraising constitutes a decisive step for future growth of the company with our partners in Europe, America
and Asia. It will enable us to significantly strengthen our financial structure, in particular to no longer hold any financial instruments
based on variable-rate convertible bonds, and to prepare for the launch of the phase 3 clinical trial in sarcopenia through our Chinese
joint-venture”.
Use of proceeds:
The company intends to use the net proceeds from
the Offering to:
| - | Establish the previously announced joint venture in Hong Kong with our partner Ronghui Renhe, dedicated
to launching our clinical study in sarcopenia (phase 3 of the SARA clinical program, a world first in medical research). |
| - | Prepare the clinical trial in obesity (phase 2 of the OBA clinical program), supporting regulatory
activities and finalizing partnerships in Brazil to enable this clinical trial to be set up. |
| - | Expand our AI drug discovery platform in longevity in partnership with Lynx Analytics. |

| - | Repayment of variable rate convertible bonds and straight debt, i.e. ORNANE contract held
by Atlas Capital for €1,025,000 and bond straight debt held by Hexagon Capital Fund for €245,379. |
| - | Cover Biophytis' operating expenses, ensuring business continuity and extending the Company's cash
flow horizon to approximately six months (combination of net proceeds from the Offering and plain-vanilla bond financing capacity). |
Terms of the issue
Nature and type of the Issue: the Issue,
for a total gross amount of €2,015,000 (including share issue premium), was carried out through the issuance, without preferential
subscription rights and without a priority subscription period, in favor of investors falling within the categories defined by the third
resolution of the shareholders’ meeting held on November 13, 2025, of (i) shares (the “New Shares”) with share
subscription warrants attached, two ordinary shares being accompanied by three share subscription warrants (the “BSA” and
with the New Shares, the “ABSA”) and (ii) pre-funded warrants (the “Pre-Funded Warrants”), every
two Pre-Funded Warrants being accompanied by three BSA.
Number of securities and pricing of the Issue:
As part of the Issue, 30,957,144 New Shares, 27,397,060 Pre-Funded Warrants and 87,531,306 Warrants are issued.
The issue price of one New Share was set at €0.035
(€0.002 of par value and €0.033 of issue premium), representing a discount of 23.4% compared to the weighted average price of
the Company's shares over the last five trading days prior to the setting of the issue price.
The issue price of one Pre-Funded Warrant was
set at €0.034, with an exercise price of €0.001 per share, representing the same discount compared to the weighted average price
of the Company's shares.
Legal framework of the Issue: Making use
of the delegation granted by the shareholders’ meeting dated November 13, 2025 pursuant to its third resolution, the Board of Directors,
held on February 23, 2026, decided on the principle of issuing New Shares and Pre-Funded Warrants, to which stock warrants are attached,
with the removal of preferential subscription rights. It sub-delegated the power to launch and define the precise characteristics of the
Issue to the Company's Chief Executive Officer.
Characteristics of Pre-Funded Warrants:
Each Pre-Funded Warrant entitles the holder to subscribe to one new share at an exercise price of €0.001.
Characteristics of the BSA: Each unit composed
of two New Shares or two Pre-Funded Warrants is accompanied by three BSA. Each BSA entitles the holder to subscribe to one new Biophytis
share, at an exercise price of €0.0385 per share. The BSA may be exercised within 60 months from the issuance date.
Settlement-delivery and admission to trading:
Settlement-delivery of the ABSA and Pre-Funded Warrants is expected on March 13, 2026. The New Shares, BSA and Pre-Funded Warrants will
be immediately detached upon issuance. The New Shares and BSA are expected to be admitted to trading on Euronext Growth on March 14, 2026.
New Shares Underlying the BSA: The new
shares that may be issued upon exercise of the BSA will be ordinary shares subject to all statutory provisions and treated as existing
shares from their date of issue. They will carry current dividend rights and will be admitted to trading on the Euronext Growth Paris
market on the same listing line as the Company's shares already listed under the same ISIN code: FR001400OLP5 – ALBPS.
Impact of the issue on the company's shareholding
structure
Following the issuance of the New Shares,
the Company's total share capital will be at €183,301.84, consisting of 91,650,918 common shares. Following the exercise of all
the Pre-Funded Warrants (and therefore the issuance of 27,397,060 additional common shares), the Company's total share capital will
be at €238,095.96, consisting of 119,047,978 common shares. Following the issuance of the New Shares, the exercise of all
Pre-Funded Warrants and the exercise of all the BSA, 145,885,510 new shares will be issued for a total of 206,579,284 shares for a
share capital of €413,158.57. 58,354,204 ordinary shares (96% of the Company's
current total share capital) would therefore be issued as part of the Issue (before exercise of the BSA but after exercise of the Pre-Funded
Warrants), or 145,885,510 ordinary shares (240% of the Company's current total share capital) after exercise of all the BSA.
By way of illustration, a shareholder holding
1% of the Company's outstanding share capital prior to the completion of the offer and who did not participate in the offer would hold
0.51% of the Company's outstanding share capital and voting rights after the issuance of the ABSA and exercise of all of the Pre-Funded
Warrants, and 0.29% of the Company's outstanding share capital and voting rights if all of the BSA are exercised.
To the best of the Company's knowledge, immediately
prior to the completion of the Issue, the breakdown of the Company's share capital was as follows:
| (1) | Before the exercise of the BSA and the Pre-Funded Warrants |
| (2) | Theorical voting rights (i.e., including treasury shares without voting rights). |
| (3) | Shares held by Company itself under the liquidity contract. |
To the best of the Company's knowledge, after
the issuance of the New Shares and exercise of Pre-Funded Warrants (but before the exercise of all BSA), the breakdown of the Company's
share capital would be as follows:

| (1) | Before the exercise of the BSA but after exercise of the Pre-Funded Warrants. |
| (2) | Theorical voting rights (i.e., including treasury shares without voting rights). |
| (3) | Shares held by Company itself under the liquidity contract. |
To the best of the Company's knowledge, after
the issuance of the New Shares, exercise of the Pre-Funded Warrants and exercise of all the BSA, the breakdown of the Company's share
capital would be as follows:
| (1) | After the exercise of the BSA. |
| (2) | Theorical voting rights (i.e., including treasury shares without voting rights). |
| (3) | Shares held by Company itself under the liquidity contract. |
Admission to trading of the new shares and
BSA
The New Shares and (upon request of the holder)
the BSA are expected to be admitted to trading on Euronext Growth on March 14, 2026. The New Shares and any new share resulting from the
exercise of the BSA and the Pre-Funded Warrants will be subject to the provisions of the Company’s bylaws and will be assimilated
to existing shares upon final completion of the Issue. They will bear current dividend rights and will be admitted to trading on the same
listing line as the Company’s existing shares under the same ISIN code FR0012816825.
Standstill and lock-up agreements
In connection with the Placement, the Company
has entered into a standstill agreement for a period of 90 calendar days from the settlement date of the Placement, subject to certain
customary exceptions. The Company's directors, its chief executive officer and certain managers have signed a lock-up agreement effective
as of the date of execution of said agreement and which will continue for a period of 90 calendar days following the date of issue of
the ABSAs in respect of their entire holdings, subject to certain customary exceptions.
Debt rescheduling with Kreos Capital
The capital increase is accompanied by a rescheduling
of the debt contracted with Kreos Capital (managed by BlackRock). The company has entered into an agreement to reschedule the repayment
of a residual debt totaling €1,224,786.72. This agreement provides for a three-month moratorium covering the period from March to
May 2026 inclusive. At the end of this period, the debt will be repaid in accordance with a schedule of 30 monthly installments of €40
thousand (interest and principal), extending from June 2026 to July 2029.
Financial intermediaries
Maxim Group LLC acted as lead placement agent
and All Invest acted as co-placement agent (collectively, the “Placement Agents”) in connection with the Placement.
The Placement is governed by agreements entered into between the Company and each of the Placement Agents.

Risk factors
The public's attention is drawn to the risk factors
relating to the Company and its business, as presented in the 2024 annual financial report and the 2025 half-yearly financial report,
available free of charge on its website (https://www.biophytis.com/informations-reglementees-pour-l-amf/). The occurrence of all
or part of these risks could have an adverse effect on the Company's business, financial position, results, development, or prospects.
Investors are also invited to consider the following
risks specific to the Placement: (i) the market price of the Company's shares may fluctuate and fall below the subscription price of the
shares issued as part of the Placement, (ii) the volatility and liquidity of the Company's shares may fluctuate significantly, (iii) sales
of the Company's shares may take place on the market and have a negative impact on the price of the Company's shares, (iv) shareholders
of the Company who did not participate in the Placement may suffer potentially significant dilution resulting from the exercise of the
BSA and, more generally, from any future capital increase made necessary by the Company's search for financing.
No prospectus
This Placement does not give rise to the publication
of a prospectus subject to approval by the Financial Markets Authority.
The information described in accordance with AMF
Position-Recommendation DOC-2020-06 “Guide to the preparation of prospectuses and information to be provided in the event of
a public offering or admission of financial securities” is included in this press release.
About BIOPHYTIS
Biophytis SA is a clinical-stage biotechnology
company focused on developing drug candidates for age-related diseases. BIO101 (20-hydroxyecdysone), our lead drug candidate, is a small
molecule in development for muscular diseases (sarcopenia, Phase 3 ready to start) and metabolic disorders (obesity, Phase 2 ready to
start). The company is headquartered in Paris, France, with subsidiaries in Cambridge, Massachusetts, USA, and Brazil. The Company’s
ordinary shares are listed on Euronext Growth Paris (ALBPS - FR001400OLP5) and its ADS (American Depositary Shares) are listed on the
OTC market (BPTSY - US 09076G401). For more information, visit www.biophytis.com.
Biophytis Contacts
Investor Relations
Investors@biophytis.com
Media contacts
Antoine Denry: antoine.denry@taddeo.fr –
+33 6 18 07 83 27
Nizar Berrada : nizar.berrada@taddeo.fr -
+33 6 38 31 90 50
* * *
This announcement is an advertisement and not
a prospectus within the meaning of Regulation (EU) 2017/1129 of the European Parliament and of the Council of 14 June 2017, as amended
(the “Prospectus Regulation”).
In France, the offer of Biophytis (the “Company”)
shares described below will be made exclusively in the context of a capital increase reserved to the category of beneficiaries, within
the meaning of Article L. 225-138 of the French commercial code, defined in the third resolution of the Company’s combined shareholders’
meeting held on April 2, 2024. It shall not constitute a public offering requiring the publication of a prospectus to be approved by the
Autorité des marchés financiers.

The Company will make available to the public
an information document containing the information set out in Annex IX of the Prospectus Regulation.
With respect to Member States of the European
Economic Area, no action has been taken or will be taken to permit a public offering of the securities referred to in this press release
requiring the publication of a prospectus in any Member State. Therefore, such securities may not be and shall not be offered in any
Member State other than in accordance with the exemptions of Article 1(4) of the Prospectus Regulation or, otherwise, in cases not requiring
the publication of a prospectus under Article 3 of the Prospectus Regulation and/or the applicable regulations in such Member State.
This press release and the information it contains
are being distributed to and are only intended for persons who are (x) outside the United Kingdom or (y) in the United Kingdom and are
(i) investment professionals falling within Article 19(5) of the Financial Services and Markets Act 2000 (Financial Promotion) Order 2005,
as amended (the “Order”), (ii) high net worth entities and other such persons falling within Article 49(2)(a) to (d)
of the Order (“high net worth companies”, “unincorporated associations”, etc.) or (iii) other person to whom an
invitation or inducement to participate in investment activity (within the meaning of Section 21 of the Financial Services and Market
Act 2000) may otherwise lawfully be communicated or caused to be communicated (all such persons in (y)(i), (y)(ii) and (y)(iii) together
being referred to as “Relevant Persons”). Any invitation, offer or agreement to subscribe, purchase or otherwise acquire
securities to which this press release relates will only be engaged with Relevant Persons. Any person who is not a Relevant Person should
not act or rely on this press release or any of its contents.
This press release may not be distributed,
directly or indirectly, in or into the United States. This press release and the information contained herein does not, and will not,
constitute an offer of the Company's shares for sale or subscription, nor the solicitation of an offer to subscribe or to purchase, such
shares in the United States or any other jurisdiction where restrictions may apply. Securities may not be offered or sold in the United
States absent registration or an exemption from registration under the U.S. Securities Act of 1933, as amended (the “Securities
Act”). The shares of the Company have not been and will not be registered under the Securities Act, and the Company does not
intend to conduct a public offering in the United States.
The distribution of this press release may
be subject to legal or regulatory restrictions in certain jurisdictions. Any person who comes into possession of this press release must
inform him or herself of and comply with any such restrictions.
Any decision to subscribe for or purchase the
shares or other securities of the Company must be made solely based on information publicly available about the Company. Such information
is not the responsibility of Maxim Group LLC or of All Invest and has not been independently verified by Maxim Group LLC or All Invest.