Prudential Financial, Inc. amended its Schedule 13G to report beneficial ownership of 24,267,980 shares of Cabaletta Bio common stock, representing 11.4% of the class as reported. The filing shows shared voting power of 19,465,084 and shared dispositive power of 24,267,980, and identifies Jennison Associates LLC as the subsidiary holding these shares. The amendment is dated 05/31/2026 and was signed on 06/05/2026.
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Insights
Prudential reports an 11.4% stake via Jennison Associates LLC.
Prudential Financial submitted an amendment listing 24,267,980 shares beneficially owned, with shared voting power of 19,465,084. The filing attributes holdings to a named subsidiary, which clarifies the ownership channel.
Cash‑flow treatment and intentions for these shares are not disclosed in the excerpt; subsequent filings or public statements would show any active trading plans.
The schedule specifies beneficial ownership 24,267,980 shares (11.4%) and lists Jennison Associates LLC as the acquiring subsidiary. The filing follows Schedule 13G/A disclosure conventions for passive/managed holdings.
Investors should note this is a disclosure of position; the filing does not state any change in control intent or transaction terms.
Key Figures
Beneficial ownership:24,267,980 sharesPercent of class:11.4%Shared voting power:19,465,084 shares+2 more
5 metrics
Beneficial ownership24,267,980 sharesas reported on Schedule 13G/A
Percent of class11.4%percent of common stock class
Shared voting power19,465,084 sharesshared power to vote or direct the vote
Shared dispositive power24,267,980 sharesshared power to dispose or direct disposition
Filing date / signature05/31/2026 / 06/05/2026amendment dated and signature date
"Amendment No. 4 Cabanetta Bio, Inc. Common Stock"
A Schedule 13G/A is an amended public filing with the U.S. securities regulator that updates a previous Schedule 13G, disclosing when an individual or group holds a substantial (typically over 5%) stake in a company and is claiming a passive, non‑controlling intent. Investors monitor these updates because rising or falling holdings can signal changing confidence, potential future moves, or shifts in voting power — like watching a public ledger where large shareholders quietly adjust their positions.
Beneficial ownershipregulatory
"Amount beneficially owned: 24,267,980 (b) Percent of class: 11.4 %"
Beneficial ownership means the person or entity that actually enjoys the benefits of owning shares or other assets — such as receiving dividends, voting rights, or price gains — even if the legal title is held in another name. For investors it matters because knowing who truly controls and profits from a company reveals who can influence decisions, exposes potential conflicts of interest or hidden concentration of power, and affects transparency and risk in the stock.
Shared dispositive powerregulatory
"Shared power to dispose or to direct the disposition of: 24,267,980"
Parent holding company / subsidiaryregulatory
"Subsidiary Number of Shares Percentage Jennison Associates LLC 24,267,980 11.4"
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SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
SCHEDULE 13G
UNDER THE SECURITIES EXCHANGE ACT OF 1934
(Amendment No. 4)
Cabaletta Bio, Inc.
(Name of Issuer)
Common Stock
(Title of Class of Securities)
12674W109
(CUSIP Number)
5/31/2026
(Date of Event Which Requires Filing of this Statement)
Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
Rule 13d-1(b)
Rule 13d-1(c)
Rule 13d-1(d)
schemaVersion:
SCHEDULE 13G
CUSIP Number(s):
12674W109
1
Names of Reporting Persons
PRUDENTIAL FINANCIAL INC
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
NEW JERSEY
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
19,465,084.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
24,267,980.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
24,267,980.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
11.4 %
12
Type of Reporting Person (See Instructions)
HC
SCHEDULE 13G
Item 1.
(a)
Name of issuer:
Cabaletta Bio, Inc.
(b)
Address of issuer's principal executive offices:
2929 ARCH STREET, SUITE 600, PHILADELPHIA, PENNSYLVANIA, 19104.
Item 2.
(a)
Name of person filing:
Prudential Financial, Inc.
(b)
Address or principal business office or, if none, residence:
751 Broad Street
Newark, New Jersey 07102-3777
(c)
Citizenship:
New Jersey
(d)
Title of class of securities:
Common Stock
(e)
CUSIP No.:
12674W109
Item 3.
If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)
Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)
Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)
Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)
Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)
An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)
An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)
A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)
A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)
A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)
A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J),
please specify the type of institution:
(k)
Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.
Ownership
(a)
Amount beneficially owned:
24,267,980
(b)
Percent of class:
11.4 %
(c)
Number of shares as to which the person has:
(i) Sole power to vote or to direct the vote:
0
(ii) Shared power to vote or to direct the vote:
19,465,084
(iii) Sole power to dispose or to direct the disposition of:
0
(iv) Shared power to dispose or to direct the disposition of:
24,267,980
Item 5.
Ownership of 5 Percent or Less of a Class.
Not Applicable
Item 6.
Ownership of more than 5 Percent on Behalf of Another Person.
If any other person is known to have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, such securities, a statement to that effect should be included in response to this item and, if such interest relates to more than 5 percent of the class, such person should be identified. A listing of the shareholders of an investment company registered under the Investment Company Act of 1940 or the beneficiaries of employee benefit plan, pension fund or endowment fund is not required.
Our clients may have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, such securities which are the subject of this filing.
Item 7.
Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
If a parent holding company has filed this schedule, pursuant to Rule 13d-1(b)(ii)(G), so indicate under Item 3(g) and attach an exhibit stating the identity and the Item 3 classification of the relevant subsidiary. If a parent holding company has filed this schedule pursuant to Rule 13d-1(c) or Rule 13d-1(d), attach an exhibit stating the identification of the relevant subsidiary.
Subsidiary Number of Shares Percentage
Jennison Associates LLC IA 24,267,980 11.4
Item 8.
Identification and Classification of Members of the Group.
Not Applicable
Item 9.
Notice of Dissolution of Group.
Not Applicable
Item 10.
Certifications:
By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11.
SIGNATURE
After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.
What stake does Prudential Financial (CABA) report?
Prudential reports beneficial ownership of 24,267,980 shares, representing 11.4% of Cabaletta Bio's common stock. The Schedule 13G/A amendment identifies Jennison Associates LLC as the subsidiary holding these shares and lists voting/dispositive power amounts.
Who holds voting power for the reported CABA shares?
The filing shows shared voting power of 19,465,084 shares rather than sole voting control. Prudential reports no sole voting power for these shares and indicates shared dispositive authority for the full position.
Is Prudential the direct holder of the Cabaletta Bio shares?
The filing attributes the position to a subsidiary, listing Jennison Associates LLC with 24,267,980 shares. The Schedule 13G/A indicates the parent filed on behalf of that subsidiary rather than stating direct individual ownership.
When was this ownership amount reported?
The Schedule 13G/A amendment is dated 05/31/2026 with a signature dated 06/05/2026. These dates mark the reporting period and the amendment's execution in the filing excerpt.
Does the filing indicate Prudential will sell or buy more shares?
No transactional intent is disclosed in the excerpt. The amendment lists beneficial ownership and voting/dispositive powers but does not state any planned purchases or sales of shares.
