Alan Waxman and TSSP Sub‑Fund HoldCo report stakes in CARIS Life Sciences (NASDAQ: CAI)

Rhea-AI Filing Summary

CARIS LIFE SCIENCES, INC. Schedule 13G/A (Amendment No. 2) discloses joint reporting by TSSP Sub-Fund HoldCo, LLC and Alan Waxman regarding beneficial ownership of Common Stock. As of March 31, 2026, the filing bases percentages on 282,579,919 shares outstanding as of February 26, 2026.

The cover data show Sub-Fund HoldCo with 13,666,128 shares (listed shared voting and dispositive power) representing 4.8% and Alan Waxman with 14,385,399 shares (listed shared voting and dispositive power) representing 5.1%. The filing describes layers of entity ownership and management relationships and includes joint filing and authorization exhibits.

Insights

Corporate Governance Expert

Joint disclosure clarifies ownership and control lines across related entities.

The filing attributes shared voting and dispositive power to reported entities, listing specific share counts and a February 26, 2026 outstanding-share base of 282,579,919. It traces ownership through multiple LLCs and identifies management links between Sub-Fund HoldCo and Mr. Waxman.

Key dependencies include the holding structures named (Barnett Equity Holdings entities, TOP III Barnett Investments, Sixth Street affiliates) and the joint filing agreement. Subsequent filings could update percentages if holdings or the outstanding share count change.

Securities Compliance Specialist

Disclosure uses a standard disclaimer of beneficial ownership and attaches authorization exhibits.

The report expressly disclaims beneficial ownership of securities held directly by several named entities and attaches an Agreement of Joint Filing and an Authorization and Designation Letter. It ties percentage calculations to the issuer's Form 10-K share count disclosed on February 26, 2026.

Material filing qualifiers include the formal disclaimers and the joint-filing mechanism; cash-flow treatment and transaction intent are not part of this disclosure.

Key Figures

Shares outstanding (basis): 282,579,919 shares TSSP Sub-Fund HoldCo holdings: 13,666,128 shares Alan Waxman holdings: 14,385,399 shares +3 more

6 metrics

Shares outstanding (basis) 282,579,919 shares as of February 26, 2026

TSSP Sub-Fund HoldCo holdings 13,666,128 shares reported shared voting/dispositive power; coversheet shows <b>4.8%</b>

Alan Waxman holdings 14,385,399 shares reported shared voting/dispositive power; coversheet shows <b>5.1%</b>

Barnett Equity Holdings direct holdings 3,354,972 shares held directly by Barnett Equity Holdings, LLC (as stated in Item 4)

Sixth Street Specialty Lending Inc. direct holdings 719,271 shares held directly by Sixth Street Specialty Lending Inc. (as stated in Item 4)

Barnett Equity Holdings II direct holdings 5,960,051 shares held directly by Barnett Equity Holdings II, LLC (as stated in Item 4)

Key Terms

Agreement of Joint Filing, beneficial ownership, shared dispositive power, Authorization and Designation Letter

4 terms

Agreement of Joint Filing regulatory

"Agreement of Joint Filing incorporated by reference herein"

beneficial ownership regulatory

"each Reporting Person disclaims beneficial ownership of the securities held directly"

Beneficial ownership means the person or entity that actually enjoys the benefits of owning shares or other assets — such as receiving dividends, voting rights, or price gains — even if the legal title is held in another name. For investors it matters because knowing who truly controls and profits from a company reveals who can influence decisions, exposes potential conflicts of interest or hidden concentration of power, and affects transparency and risk in the stock.

shared dispositive power financial

"Shared Dispositive Power 13,666,128.00 (cover page data)"

Authorization and Designation Letter regulatory

"Authorization and Designation Letter, dated December 31, 2024"

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Accepted by SEC EDGAR 05/12/2026 - 04:30 PM Learn about SEC filing dates

FAQ

What ownership stake does TSSP Sub-Fund HoldCo report in CAI?

TSSP Sub-Fund HoldCo reports 13,666,128 shares, representing 4.8% of common stock. This percentage is calculated using 282,579,919 shares outstanding as of February 26, 2026 as stated in the filing.

What stake does Alan Waxman report in CARIS Life Sciences (CAI)?

Alan Waxman reports 14,385,399 shares, representing 5.1% of common stock. The filing attributes shared voting and dispositive power to the amounts shown on each cover page.

Which date is used to calculate the ownership percentages in this filing?

Percentages are calculated using 282,579,919 shares outstanding as of February 26, 2026, as disclosed in the issuer's Annual Report on Form 10-K referenced in the filing.

Do the Reporting Persons claim direct beneficial ownership of all listed shares?

No. Each Reporting Person disclaims beneficial ownership of shares held directly by named entities (Barnett Equity Holdings, Sixth Street Specialty Lending Inc., TOP III Barnett Investments, Barnett Equity Holdings II, TAO Barnett Investments).

What exhibits accompany this Amendment No. 2 to the Schedule 13G/A?

The filing references Exhibit 1 (Agreement of Joint Filing) and Exhibit 2 (Authorization and Designation Letter dated December 31, 2024), both previously filed and incorporated by reference.

SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13G

UNDER THE SECURITIES EXCHANGE ACT OF 1934

(Amendment No. 2)

CARIS LIFE SCIENCES, INC.

(Name of Issuer)

Common Stock, par value $0.001 per share

(Title of Class of Securities)

142152107

(CUSIP Number)

03/31/2026

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

Rule 13d-1(b)

Rule 13d-1(c)

Rule 13d-1(d)

schemaVersion:

SCHEDULE 13G

CUSIP Number(s): 142152107

1

Names of Reporting Persons

TSSP Sub-Fund HoldCo, LLC

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 13,666,128.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 13,666,128.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

13,666,128.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

4.8 %

12

Type of Reporting Person (See Instructions)

OO

SCHEDULE 13G

CUSIP Number(s): 142152107

1

Names of Reporting Persons

Alan Waxman

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

UNITED STATES

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 14,385,399.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 14,385,399.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

14,385,399.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

5.1 %

12

Type of Reporting Person (See Instructions)

IN, HC

SCHEDULE 13G

Item 1.
(a)	Name of issuer: CARIS LIFE SCIENCES, INC.
(b)	Address of issuer's principal executive offices: 750 W. John Carpenter Freeway, Suite 800 Irving, TX 75039
Item 2.
(a)	Name of person filing: This Amendment No. 2 to Schedule 13G is being filed jointly by TSSP Sub-Fund HoldCo, LLC ("Sub-Fund Holdco") and Alan Waxman ("Mr. Waxman" and each a "Reporting Person" and, together, the "Reporting Persons"), pursuant to an Agreement of Joint Filing incorporated by reference herein in accordance with Rule 13d-1(k)(1) under the Act.
(b)	Address or principal business office or, if none, residence: The principal business address of Sub-Fund HoldCo is as follows: c/o Sixth Street Partners, LLC 2100 McKinney Avenue Suite 1500 Dallas, TX 75201 The principal business address of Mr. Waxman is as follows: 1 Letterman Drive, Building B, Suite B6-100 San Francisco, CA 94129
(c)	Citizenship: Sub-Fund HoldCo is organized under the laws of the State of Delaware. Mr. Waxman is a citizen of the United States.
(d)	Title of class of securities: Common Stock, par value $0.001 per share
(e)	CUSIP No.: 142152107
Item 3.	If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)	Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)	Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)	Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)	Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)	An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)	An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)	A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)	A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)	A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)	A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J), please specify the type of institution:
(k)	Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.	Ownership
(a)	Amount beneficially owned: As of March 31, 2026, each of the Reporting Persons may be deemed to be the beneficial owner of the common stock, par value $0.001 per share ("Common Stock") listed on such Reporting Person's cover page. Calculation of the percentage of Common Stock beneficially owned as of March 31, 2026 is based on 282,579,919 shares of Common Stock outstanding as of February 26, 2026 as disclosed in the Issuer's Annual Report filed on Form 10-K filed with the Securities and Exchange Commission on March 3, 2026. As of March 31, 2026, 3,354,972 shares of Common Stock are held directly by Barnett Equity Holdings, LLC, 719,271 shares of Common Stock are held directly by Sixth Street Specialty Lending Inc., 2,290,056 shares of Common Stock are held directly by TOP III Barnett Investments, LLC, 5,960,051 shares of Common Stock are held directly by Barnett Equity Holdings II, LLC and 2,061,049 shares of Common Stock are held directly by TAO Barnett Investments, LLC. TAO SPV GP, LLC, a Delaware limited liability company, is the managing member of each of (i) Barnett Equity Holdings, LLC; (ii) Barnett Equity Holdings II LLC; and (iii) TAO Barnett Investments, LLC. Empire SPV GP, LLC, a Delaware limited liability company, is the managing member of TOP III Barnett Investments, LLC. Sub-Fund HoldCo is the sole member of each of TAO SPV GP, LLC and Empire SPV GP, LLC. Sixth Street Specialty Lending, Inc. is managed by Sixth Street Specialty Lending Advisers, LLC, a Delaware limited liability company. TSSP Holdco Management, LLC, a Delaware limited liability company ("Holdco Management"), manages Sixth Street Specialty Lending Advisers Holdings, LLC, a Delaware limited liability company. The business and affairs of Sixth Street Specialty Lending Advisers, LLC are managed by Sixth Street Specialty Lending Advisers Holdings, LLC, the sole member of Sixth Street Specialty Lending Advisers, LLC. Sub-Fund HoldCo is managed by its sole member, whose managing member is Mr. Waxman. Holdco Management is managed by a board of directors, which is currently comprised of Mr. Waxman. Mr. Waxman is the CEO of Holdco Management. Each Reporting Person disclaims beneficial ownership of the securities held directly by Barnett Equity Holdings, LLC, Sixth Street Specialty Lending Inc, TOP III Barnett Investments, LLC, Barnett Equity Holdings II, LLC and TAO Barnett Investments, LLC. Neither the filing of this Schedule 13G nor any of its contents shall be deemed to constitute an admission that any Reporting Person is the beneficial owner of the Common Stock referred to herein for purposes of Section 13(d) of the Securities Exchange Act of 1934, as amended, or for any other purpose.
(b)	Percent of class: See each cover page hereof.
(c)	Number of shares as to which the person has:
	(i) Sole power to vote or to direct the vote: See each cover page hereof.
	(ii) Shared power to vote or to direct the vote: See each cover page hereof.
	(iii) Sole power to dispose or to direct the disposition of: See each cover page hereof.
	(iv) Shared power to dispose or to direct the disposition of: See each cover page hereof.
Item 6.	Ownership of more than 5 Percent on Behalf of Another Person.
	Not Applicable
Item 7.	Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
	Not Applicable
Item 8.	Identification and Classification of Members of the Group.
	Not Applicable
Item 9.	Notice of Dissolution of Group.
	Not Applicable

Item 10.	Certifications:
	Not Applicable

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

TSSP Sub-Fund HoldCo, LLC

Signature:	/s/ Joshua Peck
Name/Title:	Joshua Peck, Vice President
Date:	05/12/2026

Alan Waxman

Signature:	/s/ Joshua Peck
Name/Title:	Joshua Peck, on behalf of Alan Waxman (*)
Date:	05/12/2026

Comments accompanying signature: Joshua Peck is signing on behalf of Mr. Waxman pursuant to an authorization and designation letter dated December 31, 2024.

Exhibit Information

Exhibit 1 - Agreement of Joint Filing (previously filed) Exhibit 2 - Authorization and Designation Letter, dated December 31, 2024, by Alan Waxman (previously filed)