[Form 4] Clene Inc. Insider Trading Activity

Rhea-AI Filing Summary

Clene Inc. (CLNN) insider sale reported. General Resonance LLC reported a sale of 3,401 shares of Clene common stock on 08/21/2025 at a price of $5.34 per share, leaving beneficial ownership of 704,591 shares. The Form 4 was filed by one reporting person and signed by Heidi Ley.

Insights

Financial Analyst

TL;DR: Insider reported a routine sale of 3,401 shares; change appears limited in scale relative to total holdings.

The Form 4 discloses a single non-derivative sale of 3,401 shares on 08/21/2025 at $5.34, reducing beneficial ownership to 704,591 shares. The filing is straightforward with no derivative transactions or amendments noted. This appears to be a routine Section 16 disclosure without additional context or plan language disclosed.

Corporate Governance Expert

TL;DR: Disclosure complies with Section 16; transaction is reported and signed, indicating procedural completeness.

The document identifies General Resonance LLC as the reporting person and indicates the filer is a director and 10% owner. The sale is reported on Form 4 and manually signed. There is no indication of Rule 10b5-1 plan reliance or other arrangements in the provided text.

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
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Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

General Resonance LLC

(Last) (First) (Middle)

6510 SOUTH MILLROCK DRIVE, SUITE 250

(Street)

HOLLADAY, UT 84121

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
Clene Inc. [ CLNN ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director	X	10% Owner
	Officer (give title below)		Other (specify below)

3. Date of Earliest Transaction (Month/Day/Year)
08/21/2025

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	08/21/2025		S		3,401	D	$5.34	704,591	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

	/s/ Heidi Ley	08/21/2025
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What insider transaction was reported for Clene (CLNN)?

The Form 4 reports a sale of 3,401 shares of Clene common stock.

When was the Clene (CLNN) insider sale executed?

The transaction date recorded is 08/21/2025.

At what price were the Clene (CLNN) shares sold?

The reported sale price is $5.34 per share.

How many Clene (CLNN) shares does the reporting person own after the sale?

The reporting person beneficially owns 704,591 shares following the transaction.

Who signed the Form 4 for this Clene (CLNN) transaction?

The Form 4 is signed by /s/ Heidi Ley dated 08/21/2025.