[Form 4] Clene Inc. Insider Trading Activity

Rhea-AI Filing Summary

Clene Inc. insider grant: Director Shalom Jacobovitz was granted a non-qualified stock option for 5,534 shares of Clene Inc. common stock on 08/14/2025 under the Clene Inc. Amended 2020 Stock Plan at an exercise price of $3.60 per share. The option vests immediately upon grant and is exercisable through 08/13/2035. Following the grant, the reporting person beneficially owns 5,534 underlying shares and exercised price per share for reporting is shown as $0 (reflecting the reporting field for shares beneficially owned). The Form 4 was signed by a POA on 08/15/2025.

Insights

Corporate Governance Expert

TL;DR: A director received an immediately vested option for 5,534 shares at $3.60, a routine director compensation event with limited immediate governance implications.

The grant to a director under the company's 2020 Stock Plan is disclosed clearly: 5,534 options, $3.60 exercise price, immediate vesting, and a 10-year contractual term to 08/13/2035. This is a common form of equity compensation for board members. The immediate vesting is notable as it removes future service conditions, but the absolute size is small relative to typical outstanding share counts for most issuers. Disclosure appears complete for Section 16 reporting purposes.

Securities Analyst

TL;DR: Small, immediately vested option grant to a director; unlikely to be material to CLNN financials or capitalization.

The Form 4 records a non-derivative derivative (stock option) granted 08/14/2025 for 5,534 shares at $3.60 exercise, exercisable immediately and expiring 08/13/2035. The filing shows the reporting person beneficially owns 5,534 shares post-transaction. For investors, the record meets regulatory transparency standards; the transaction size suggests limited dilution or cash flow impact. No additional transactions or changes in ownership percentages are reported.

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

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Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Jacobovitz Shalom

(Last) (First) (Middle)

6550 SOUTH MILLROCK DRIVE

SUITE G50

(Street)

SALT LAKE CITY UT 84121

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
Clene Inc. [ CLNN ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director		10% Owner
	Officer (give title below)		Other (specify below)

3. Date of Earliest Transaction (Month/Day/Year)
08/14/2025

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
stock option	$3.6	08/14/2025		A		5,534		(1)	08/13/2035	common stock	5,534	$0	5,534	D

Explanation of Responses:

1. This option was granted on August 14, 2025 as an option for 5,534 share of Common Stock under the Clene Inc. Amended 2020 Stock Plan at an exercise price of $3.60 per share. The options vest immediately upon grant.

	/s/ Jerome T. Miraglia POA	08/15/2025
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What transaction did Clene Inc. (CLNN) report on the Form 4?

The Form 4 reports a grant of a stock option for 5,534 shares to director Shalom Jacobovitz on 08/14/2025.

What are the exercise price and expiration date of the option reported for CLNN?

The option has an exercise price of $3.60 per share and an expiration date of 08/13/2035.

Does the reported option vest immediately or over time?

The option vests immediately upon grant, according to the Form 4 explanation of responses.

How many shares does the reporting person beneficially own after the transaction?

The reporting person beneficially owns 5,534 shares following the reported transaction.

Who signed the Form 4 and when was it filed?

The Form 4 was signed by /s/ Jerome T. Miraglia POA on 08/15/2025.