Clearmind Medicine (NASDAQ: CMND) flags going concern risk after $5.9M loss
Clearmind Medicine Inc. filed a Form 6-K furnishing its unaudited interim financial statements and MD&A for the three and six months ended April 30, 2026. The company reported a net loss of $2.0M for the quarter and $5.9M for the first half, driven by higher general and administrative and research expenses as it advances clinical trials.
Cash and cash equivalents were $11.4M as of April 30, 2026, with total assets of $14.5M and working capital of about $11.3M. Operating activities used $3.9M of cash in the six-month period, while equity financings and convertible promissory notes brought in significant funds.
Management discloses substantial doubt about the company’s ability to continue as a going concern, citing an accumulated deficit of $33.8M, ongoing losses, and dependence on additional debt or equity financing. During the period, an independent Data and Safety Monitoring Board issued multiple positive safety reviews for the Phase I/IIa CMND‑100 trial for Alcohol Use Disorder, allowing escalation to higher-dose cohorts. The company also completed reverse share splits and continues to carry sizable derivative warrant liabilities linked to prior financings.
Positive
- Liquidity bolstered: Cash and cash equivalents reached $11.4M and working capital about $11.3M as of April 30, 2026, after multiple equity and convertible note financings.
- Clinical trial momentum: The independent Data and Safety Monitoring Board issued three consecutive positive safety reviews for the Phase I/IIa CMND‑100 trial in Alcohol Use Disorder, allowing escalation to a 160mg dose cohort.
Negative
- Going concern warning: Management states that recurring losses, negative operating cash flows and dependence on future financings raise substantial doubt about Clearmind’s ability to continue as a going concern.
- Rising losses and dilution risk: Six‑month net loss widened to $5.9M, while convertible notes of $8.15M principal plus interest were converted into 802,622 shares and 370,038 warrant shares remain at a reset exercise price of $6.00.
Insights
Clearmind shows trial progress but faces going concern risk and heavy dilution from structured financings.
Clearmind Medicine remains a pre-revenue biotech, posting a six-month net loss of $5.9M and operating cash outflow of $3.85M. Spending stepped up, with general and administrative costs rising to $3.94M and research and development to $1.29M as the Phase I/IIa CMND‑100 trial advances.
Liquidity improved on paper: cash reached $11.4M and working capital about $11.3M as of April 30, 2026, supported by equity raises and convertible promissory notes. However, management explicitly states that recurring losses and reliance on external funding raise substantial doubt about the ability to continue as a going concern.
Structured financing is central to the story. Promissory notes up to $10.0M in principal were arranged, with $8.15M plus interest already converted into 802,622 shares, and warrant terms reset to an exercise price of $6.00 per share with 370,038 warrant shares outstanding. This combination of convertibles, derivative warrant liabilities of $2.14M, and repeated reverse splits signals meaningful dilution risk. Subsequent disclosures in future period filings will clarify whether the current cash balance is sufficient to carry CMND‑100 through its early-stage clinical milestones.
Key Figures
Key Terms
going concern financial
Phase I/IIa clinical trial medical
Data and Safety Monitoring Board medical
derivative warrant liabilities financial
Fair Value Through Profit or Loss financial
reverse split financial
AI-generated analysis. How Rhea-AI works. Not financial advice.
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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
Form
Report of Foreign Private Issuer
Pursuant to Rule 13a-16 or 15d-16
under the Securities Exchange Act of 1934
For the month of June
Commission file number:
(Translation of registrant’s name into English)
101 – 1220 West 6th Avenue
Vancouver, British
Columbia
(Address of principal executive offices)
Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F.
Form 20-F ☒ Form 40-F ☐
CONTENTS
On June 15, 2026, the registrant filed in Canada its unaudited condensed interim consolidated financial statements and Management’s Discussion and Analysis for the three and six months ended April 30, 2026, with the Canadian Securities Administration and each of the Ontario Securities Commission, British Columbia Securities Commission and Alberta Securities Commission.
This Report on Form 6-K is incorporated by reference into the Registrant’s Registration Statements on Form F-3 (File No. 333-275991, 333-270859, 333-273293, 333-290404, 333-293521 and 333-295455) and Form S-8 (File No. 333-283695), filed with the Securities and Exchange Commission, to be a part thereof from the date on which this report is submitted, to the extent not superseded by documents or reports subsequently filed or furnished.
1
EXHIBIT INDEX
| Exhibit No. | ||
| 99.1 | Condensed Interim Consolidated Financial Statements for the three and six months ended April 30, 2026. | |
| 99.2 | Management’s Discussion and Analysis for the three and six months ended April 30, 2026. | |
| 101.INS | Inline XBRL Instance Document. | |
| 101.SCH | Inline XBRL Taxonomy Extension Schema Document. | |
| 101.CAL | Inline XBRL Taxonomy Extension Calculation Linkbase Document. | |
| 101.DEF | Inline XBRL Taxonomy Extension Definition Linkbase Document. | |
| 101.LAB | Inline XBRL Taxonomy Extension Label Linkbase Document. | |
| 101.PRE | Inline XBRL Taxonomy Extension Presentation Linkbase Document. | |
| 104 | Cover Page Interactive Data File (formatted as Inline XBRL and contained in Exhibit 101). |
2
SIGNATURES
Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.
| Clearmind Medicine Inc. | |||
| Date: June 15, 2026 | By: | /s/ Adi Zuloff-Shani | |
| Name: | Adi Zuloff-Shani | ||
| Title: | Chief Executive Officer | ||
3
Exhibit 99.1
CLEARMIND MEDICINE INC.
Condensed Interim Consolidated Financial Statements
For The Three And Six Months Ended April 30, 2026
(Expressed in United States Dollars)
(Unaudited)
CLEARMIND MEDICINE INC.
Condensed Interim Consolidated Statements of Financial Position
(Expressed in United States Dollars)
(Unaudited)
| April 30, | October 31, | |||||||
| 2026 | 2025 | |||||||
| Assets | ||||||||
| Current assets | ||||||||
| Cash and cash equivalents | $ | $ | ||||||
| Other receivables | ||||||||
| Short-term investments (Note 3) | ||||||||
| Prepaid expenses | ||||||||
| Related parties (Note 4b) | ||||||||
| Total current assets | ||||||||
| Non-current assets | ||||||||
| Intangible assets | ||||||||
| Restricted cash | ||||||||
| Right-of-use asset (Note 14e) | ||||||||
| Total non-current assets | ||||||||
| Total assets | $ | $ | ||||||
| Liabilities | ||||||||
| Current liabilities | ||||||||
| Accounts payable and accrued liabilities | $ | $ | ||||||
| Due to related parties (Note 4a) | ||||||||
| Derivative warrant liabilities (Note 5) | ||||||||
| Short-term portion of lease liabilities (Note 14e) | ||||||||
| Convertible loans (Note 6) | - | |||||||
| Total current liabilities | ||||||||
| Long-term lease liabilities | - | |||||||
| Total non-current liabilities | - | |||||||
| Total liabilities | $ | $ | ||||||
| Shareholders’ equity | ||||||||
| Share capital and share premium (Note 7) | ||||||||
| Warrants (Note 8) | ||||||||
| Share-based payment reserve (Notes 9, 10) | ||||||||
| Accumulated other comprehensive loss | ( | ) | ( | ) | ||||
| Accumulated deficit | ( | ) | ( | ) | ||||
| Total shareholders’ equity | ||||||||
| Total liabilities and shareholders’ equity | $ | $ | ||||||
Approved and authorized for issuance on behalf of the Board of Directors on June 15, 2026:
| /s/ Alan Rootenberg | /s/ Adi Zuloff-Shani | |
| Alan Rootenberg, CFO | Adi Zuloff-Shani, CEO |
(The accompanying notes are an integral part of these condensed interim consolidated financial statements)
F-1
CLEARMIND MEDICINE INC.
Condensed Interim Consolidated Statements of Operations and Comprehensive Loss
(Expressed in United States Dollars)
(Unaudited)
| Three months ended | Six months ended | |||||||||||||||
| April 30, | April 30, | |||||||||||||||
| 2026 | 2025 | 2026 | 2025 | |||||||||||||
| Operating expenses | ||||||||||||||||
| General and administrative | $ | $ | $ | $ | ||||||||||||
| Research and development, net | ||||||||||||||||
| Total operating expenses | ||||||||||||||||
| Finance income (expenses) | ||||||||||||||||
| Changes in fair value of derivative warrant liabilities (Note 5) | ( | ) | ( | ) | ||||||||||||
| Changes in fair value of short-term investments (Note 3) | ( | ) | ( | ) | ( | ) | ||||||||||
| Foreign exchange gain | ( | ) | ||||||||||||||
| Other finance expenses | ( | ) | ( | ) | ( | ) | ( | ) | ||||||||
| Interest income on deposits | ||||||||||||||||
| Changes in fair value of convertible loans (Note 6) | ( | ) | - | ( | ) | - | ||||||||||
| Total finance income | ( | ) | ( | ) | ||||||||||||
| Loss before taxes | ( | ) | ( | ) | ( | ) | ( | ) | ||||||||
| Tax expenses | ( | ) | ( | ) | ( | ) | ( | ) | ||||||||
| Net Loss and Comprehensive loss | $ | ( | ) | $ | ( | ) | $ | ( | ) | $ | ( | ) | ||||
| Loss per share, basic and diluted | $ | ( | ) | $ | ( | ) | $ | ( | ) | $ | ( | ) | ||||
| Weighted average number of shares outstanding for the purposes of basic and diluted loss per share | ||||||||||||||||
| (*) | On December 15, 2025, the Company effected a 1-for-40 reverse split of its issued and outstanding common shares and on May 21, 2026, the Company effected a further 1-for-10 reverse split of its issued and outstanding common shares (the “Reverse Splits”). Following the Reverse Splits, holders of the Company’s common shares received 0.0025 of a common share for every one common share held. All share amounts have been retroactively adjusted for all periods presented. |
(The accompanying notes are an integral part of these condensed interim consolidated financial statements)
F-2
CLEARMIND MEDICINE INC.
Condensed Interim Statements of Changes in Shareholders’ Equity
(Expressed in United States Dollars)
(Unaudited)
| Share capital and share premium | Share-based | Accumulated other | Total | |||||||||||||||||||||||||
| Number of shares (*) | Amount | Warrants | payment reserve | comprehensive income | Accumulated deficit | shareholders’ equity | ||||||||||||||||||||||
| Balance, October 31, 2025 | | $ | $ | $ | $ | ( | ) | $ | ( | ) | $ | |||||||||||||||||
| Net loss for the period | – | – | – | – | – | ( | ) | ( | ) | |||||||||||||||||||
| Exercise of warrants (Notes 7c(iii, viii)) | – | – | – | – | ||||||||||||||||||||||||
| Issuance of common shares upon vesting of restricted share units (Notes 7c(iv, vi)) | – | ( | ) | – | – | – | ||||||||||||||||||||||
| Issuance of shares upon conversion of convertible loans (Notes 6, 7c(i, ix)) | – | – | – | – | ||||||||||||||||||||||||
| Issuance of common shares (Note 7c(ii)) | – | – | – | – | ||||||||||||||||||||||||
| Share-based compensation (Notes 7c(v,vi, vii), 9, 10) | – | – | – | – | ||||||||||||||||||||||||
| Balance, April 30, 2026 | $ | $ | $ | $ | ( | ) | $ | ( | ) | $ | ||||||||||||||||||
| Balance, October 31, 2024 | $ | $ | $ | $ | ( | ) | $ | ( | ) | $ | ||||||||||||||||||
| Net loss for the period | – | – | – | – | – | ( | ) | ( | ) | |||||||||||||||||||
| Exercise of warrants | – | – | – | – | ||||||||||||||||||||||||
| Issuance of common shares upon vesting of restricted share units | – | ( | ) | – | – | – | ||||||||||||||||||||||
| Share-based compensation | – | – | – | – | – | |||||||||||||||||||||||
| Balance, April 30, 2025 | $ | $ | $ | $ | ( | ) | $ | ( | ) | $ | ||||||||||||||||||
| (*) | On December 15, 2025, the Company effected a 1-for-40 reverse split of its issued and outstanding common shares and on May 21, 2026, the Company effected a further 1-for-10 reverse split of its issued and outstanding common shares. Following the Reverse Splits, holders of the Company’s common shares received 0.0025 of a common share for every one common share held. All share amounts have been retroactively adjusted for all periods presented. |
(The accompanying notes are an integral part of these condensed interim consolidated financial statements)
F-3
CLEARMIND MEDICINE INC.
Condensed Interim Consolidated Statements of Cash Flows
(Expressed in United States Dollars)
(Unaudited)
| Six months ended April 30, | ||||||||
| 2026 | 2025 | |||||||
| Operating activities | ||||||||
| Net loss for the period | $ | ( | ) | $ | ( | ) | ||
| Adjustments for: | ||||||||
| Amortization of intangible assets | ||||||||
| Amortization of right-of-use asset | ||||||||
| Interest on lease liability | ||||||||
| Exchange rate differences | ( | ) | ||||||
| Changes in fair value of derivative warrant liabilities | ( | ) | ||||||
| Interest on convertible loans | – | |||||||
| Share-based compensation | ||||||||
| Changes in fair value of short-term investments | ||||||||
| Changes in working capital: | ||||||||
| (Increase) decrease in other receivables | ( | ) | ||||||
| Increase in prepaid expenses | ( | ) | ( | ) | ||||
| Increase (decrease) in accounts payable and accrued liabilities | ( | ) | ||||||
| Decrease in amounts due to / from related parties | ( | ) | ( | ) | ||||
| Net cash used in operating activities | ( | ) | ( | ) | ||||
| Investing activities | ||||||||
| Acquisition of short-term investment (Note 3) | ( | ) | ( | ) | ||||
| Proceeds of short-term investment | – | |||||||
| Changes in restricted cash | – | ( | ) | |||||
| Net cash used in investing activities | ( | ) | ( | ) | ||||
| Financing activities | ||||||||
| Proceeds received from issuance of shares (Note 7c (ii)) | – | |||||||
| Proceeds received from convertible loans (Note 6) | – | |||||||
| Proceeds received from exercise of warrants (Notes 7c (iii, viii)) | ||||||||
| Repayment of lease liabilities | ( | ) | ( | ) | ||||
| Net cash provided by financing activities | ||||||||
| Effect of foreign exchange rate changes on cash and cash equivalents | ( | ) | ||||||
| Net increase (decrease) in cash and cash equivalents | ( | ) | ||||||
| Cash and cash equivalents at beginning of period | ||||||||
| Cash and cash equivalents at end of period | $ | $ | ||||||
| Supplementary disclosure of cash flow information: | ||||||||
| Cash received as interest | $ | $ | ||||||
| Cash paid in respect of taxes | ||||||||
| Cash paid as interest on lease liability | – | |||||||
| Non-cash financing and investing activities | ||||||||
| Issuance of shares upon conversion of convertible loans (Notes 6,7c (i, ix)) | $ | $ | – | |||||
| Right of use assets obtained in exchange for lease liabilities | $ | $ | – | |||||
(The accompanying notes are an integral part of these condensed interim consolidated financial statements)
F-4
CLEARMIND MEDICINE INC.
Notes to the Condensed Interim Consolidated Financial Statements
(Expressed in United States Dollars)
(Unaudited)
| 1. | Nature of Operations and Going Concern |
| a. | Clearmind Medicine Inc. (the “Company”) was incorporated
in the province of British Columbia on |
The Company trades under the symbol “CMND” on the Nasdaq Capital Market. The Company was listed on the Canadian Securities Exchange (“CSE”) in Toronto until March 14, 2024. Following approval for a voluntary delisting, the Company no longer trades on the CSE, but remains a reporting issuer in Canada.
| b. | Going concern |
These condensed interim consolidated
financial statements have been prepared on the going concern basis, which assumes that the Company will be able to realize its assets
and discharge its liabilities in the normal course of business. For the six months ended April 30, 2026, the Company had not generated
any revenues and had negative cash flows from operations of $
| c. | Reverse share splits |
On December 15, 2025, the Company effected
a
All issued and outstanding common shares or instruments convertible into common shares contained in these financial statements have been retroactively adjusted to reflect the reverse share splits for all periods presented, unless explicitly stated otherwise.
F-5
CLEARMIND MEDICINE INC.
Notes to the Condensed Interim Consolidated Financial Statements
(Expressed in United States Dollars)
(Unaudited)
| 1. | Nature of Operations and Going Concern (continued) |
| d. | On October 7, 2023, Hamas launched a series of attacks on civilian and military targets in Southern Israel and Central Israel, to which the Israel Defense Forces responded. In addition, Iran, Hezbollah and the Houthi movement attacked military and civilian targets in Israel, to which Israel responded, including through increased air and/or ground operations in Lebanon, Syria, Yemen and Iran. Following years of conflict in the region, on October 9, 2025, Israel, Hamas, the United States and other countries in the region agreed to a framework for a ceasefire in Gaza between Israel and Hamas. On February 28, 2026, the United States and Israel launched joint combat operations in Iran to which Iran and Hezbollah responded with ballistic missile and drone attacks on Israel as well as other countries and U.S. military bases in the region. On April 8, 2026, the United States and Iran agreed to a two-week ceasefire. How long and how severe the current conflicts in Gaza, Northern Israel, Lebanon, Iran or the broader region last and become is unknown at this time and any continued clash among Israel, Hamas, Hezbollah, Iran or other countries or militant groups in the region may escalate in the future into a greater regional conflict. The intensity and duration of the security situation in Israel have been difficult to predict, as are the economic implications on our business and operations and on Israel’s economy in general. As of the date of these consolidated financial statements, conflict continues in parts of the region. The Company’s clinical trials, the laboratory that supports such clinical trials and the Contract Research Organization (CRO) are based in Israel. The extent to which the security situation in Israel may impact the Company’s financial condition, results of operations, or liquidity is uncertain, and as of the date of issuance of these condensed interim consolidated financial statements, the Company is not aware of any specific event or circumstance that would require an update to its estimates or judgments or an adjustment to the carrying value of the Company’s assets or liabilities as of April 30, 2026. |
| 2. | Material Accounting Policy Information |
| a. | Basis of Presentation |
The accompanying condensed interim consolidated financial statements have been prepared in accordance with International Financial Reporting Standards (“IFRS”), as issued by the International Accounting Standards Board (“IASB”) on a going concern basis.
These condensed interim consolidated financial statements include the accounts of the Company and its wholly-owned subsidiaries, Clearmindmed Ltd., Clearmind Labs Corp. and Clearmind Buzz Inc, incorporated in Ontario, Canada on March 18, 2026, and currently inactive. All inter-company balances and transactions have been eliminated on consolidation.
These condensed interim consolidated financial statements have been prepared on a historical cost basis, except for financial assets and liabilities (including derivatives) which are presented at fair value through profit or loss (“FVTPL”).
These unaudited condensed interim consolidated financial statements have been prepared in accordance with the requirements of International Accounting Standard IAS 34 “Interim Financial Reporting” as issued by the IASB. They do not include all the information required in annual financial statements in accordance with IFRS accounting standards and should be read in conjunction with the annual financial statements of the Company for the year ended October 31, 2025.
| b. | Condensed Interim Consolidated Financial Information |
Certain information and footnote disclosures normally included in financial statements prepared in accordance with IFRS have been condensed or omitted from this report, as is permitted by such rules and regulations. Accordingly, these condensed interim consolidated financial statements should be read in conjunction with the audited financial statements as of and for the year ended October 31, 2025 and the notes thereto (the “2025 Annual Report”).
F-6
CLEARMIND MEDICINE INC.
Notes to the Condensed Interim Consolidated Financial Statements
(Expressed in United States Dollars)
(Unaudited)
| 2. | Material Accounting Policy Information (continued) |
The condensed interim consolidated financial statements have been prepared on the same basis as the 2025 Annual Report. In the opinion of the Company’s management, these condensed interim consolidated financial statements contain all adjustments that are necessary to present fairly the Company’s financial position and results of operations for the interim periods presented. The results for the six months ended April 30, 2026 are not necessarily indicative of the results for the year ending October 31, 2026, or for any future period.
As of April 30, 2026, there have been no material changes in the Company’s significant accounting policies from those that were disclosed in the 2025 Annual Report.
| c. | Significant Accounting Estimates and Judgments |
The preparation of consolidated financial statements in accordance with IFRS requires management to make judgments, estimates, and assumptions that affect the application of policies and reported amounts of assets, liabilities, income, and expenses. The estimates and associated assumptions are based on historical experience and various other factors that are believed to be reasonable under the circumstances, the results of which form the basis of making the judgments about carrying values of assets and liabilities that are not readily apparent from other sources. Actual results may differ from these estimates.
Significant Estimates
Derivative Warrant Liabilities and Assets
The Company analyses warrants issued to determine whether they meet the classification as liabilities or equity. Derivative warrant liabilities and assets are adjusted to reflect their fair value at each reporting period, with any increase or decrease in the fair value recorded in the results of operations. The Company uses a fair valuation specialist to estimate the value of these instruments using the Black and Scholes and binomial pricing model.
The key assumptions used in the models are the expected future volatility in the price of the Company’s shares, the expected life of the warrants, the risk-free interest rate and the probability of any future adjustment event.
Significant Judgments
The critical judgments that the Company’s management has made in the process of applying the Company’s accounting policies that have the most significant effect on the amounts recognized in the Company’s consolidated financial statements are as follows:
Going Concern
The application of the going concern assumption requires management to take into account all available information about the future, which is at least but not limited to twelve months from the end of the reporting period. The Company is aware that material uncertainties related to events or conditions raise substantial doubt upon the Company’s ability to continue as a going concern.
F-7
CLEARMIND MEDICINE INC.
Notes to the Condensed Interim Consolidated Financial Statements
(Expressed in United States Dollars)
(Unaudited)
| 3. | Short-term Investments |
| October 31, 2025 | Additions | Disposals | Changes in fair value | April 30, 2026 | ||||||||||||||||
| Polyrizon Ltd. (1) | $ | $ | - | $ | - | $ | $ | |||||||||||||
| Taurus Gold Corp. (2) – shares and warrants (see also note 11(a)) | - | - | ( | ) | ||||||||||||||||
| Quantum X Labs Inc. (3) – shares and warrants (see also note 11(a)) | - | - | ||||||||||||||||||
| $ | $ | $ | - | $ | ( | ) | $ | |||||||||||||
| October 31, 2024 | Additions | Disposals | Changes in fair value | October 31, 2025 | ||||||||||||||||
| Polyrizon Ltd. (1) | $ | $ | $ | ( | ) | $ | ( | ) | $ | |||||||||||
| Taurus Gold Corp. – shares and warrants | - | - | ||||||||||||||||||
| $ | $ | $ | ( | ) | $ | $ | ||||||||||||||
| (1) | On March 31, 2025, the Company subscribed for shares, pre funded warrants and warrants to purchase shares of Polyrizon (“Polyrizon Shares”). As of October 31, 2025 and April 30, 2026, following the exercise and sale of certain Polyrizon Shares, the Company retained a balance of
On November 28, 2025, Polyrizon effected a reverse share split of its ordinary shares at the ratio of |
| (2) | During
October 2025, the Company subscribed for |
During October 2025, the Company also
purchased an additional
| (3) | On March 4, 2026, the company invested $ |
The Taurus Shares, Polyrizon Shares and QXL Shares are recorded at fair value in the Company’s Consolidated Statement of Financial Position. The October 2025 Taurus Warrants and QXL Warrants were recorded at their fair value as a derivative asset at the time of the grant and are revalued at the end of each reporting period. The changes in fair value of short-term investment were recorded to the Condensed Interim Consolidated Statements of Operations and Comprehensive Loss.
F-8
CLEARMIND MEDICINE INC.
Notes to the Condensed Interim Consolidated Financial Statements
(Expressed in United States Dollars)
(Unaudited)
| 4. | Related Party Transactions |
| a. | Compensation to key management personnel |
| (i) |
| Three months ended | Three months ended | Six months ended | Six months ended | |||||||||||||
| April 30, | April 30, | April 30, | April 30, | |||||||||||||
| 2026 | 2025 | 2026 | 2025 | |||||||||||||
| Officers: | ||||||||||||||||
| Consulting fees | $ | $ | $ | $ | ||||||||||||
| Share based compensation | - | - | ||||||||||||||
| $ | $ | $ | $ | |||||||||||||
| Directors: | ||||||||||||||||
| Directors’ fees | $ | $ | $ | $ | ||||||||||||
| Share based compensation | - | - | ||||||||||||||
| $ | $ | $ | $ | |||||||||||||
| (ii) |
| April 30, | October 31, | |||||||
| 2026 | 2025 | |||||||
| Amounts owed to officers | $ | $ | ||||||
| Amounts owed to directors | ||||||||
| $ | $ | |||||||
| b. | On March 7, 2022, the Company signed an agreement with SciSparc Ltd (“SciSparc”), pursuant to which the Company and SciSparc agreed to cooperate in conducting a feasibility study using certain molecules developed by each party (the “Cooperation Agreement”). Certain of the Company’s officers and directors currently operate, manage or are engaged as officers and/or directors of SciSparc.
In June 2023, the Company entered into a research agreement with the Hebrew University of Jerusalem to evaluate its and SciSparc’s combination treatment for obesity and metabolic syndrome.
To date, the collaboration has resulted in the filing of nine patent applications. To the extent the parties determine to proceed to a commercial cooperation, they will enter into a joint venture where the parties share the economics and rights on a
For the three and six months ended April 30, 2026, the Company incurred research and development expenses conducted within the framework of the Cooperation Agreement in the amount of $ |
F-9
CLEARMIND MEDICINE INC.
Notes to the Condensed Interim Consolidated Financial Statements
(Expressed in United States Dollars)
(Unaudited)
| 5. | Derivative warrant liabilities |
| a. | On April 6, 2023, the Company issued |
On November 14, 2025, April 2023 Warrants were exercised for
| b. | On September 18, 2023, the Company issued |
| c. | On January 16, 2024, the Company issued On November 14, 2025, January 2024 Warrants were exercised into | |
| d. | On December 15, 2025, following the Reverse Split of the Company shares noted above, the exercise prices of the January 2024 Warrants were reduced to $ | |
| e. | During the three and six months ended April 30, 2026, the Company recorded a loss on the revaluation of the total derivative warrant liabilities of $ |
| f. |
| April 30, 2026 | ||||
| Share Price | $ | |||
| Exercise Price | $ | |||
| Expected life | ||||
| Risk-free interest rate | % | |||
| Dividend yield | % | |||
| Expected volatility | % | |||
| g. |
| Balance as of October 31, 2024 | $ | |||
| Exercise of warrants | ( | ) | ||
| Change in fair value of warrants | ( | ) | ||
| Balance as of October 31, 2025 | $ | |||
| Exercise of warrants | ( | ) | ||
| Change in fair value of warrants | ||||
| Balance as of April 30, 2026 | $ |
F-10
CLEARMIND MEDICINE INC.
Notes to the Condensed Interim Consolidated Financial Statements
(Expressed in United States Dollars)
(Unaudited)
| 6. | Convertible loans |
On September 17, 2025, the Company
entered into a share purchase agreement (“SPA”) with
During November 2025, the balance owing
on the Promissory Notes ($
| During the six months ended April 30, 2026, the CLA Investors purchased additional Promissory Notes in the aggregate principal amount of $
During the six months ended April 30, 2026, the CLA Investors converted Promissory Notes in the aggregate amount of $
On February 9, 2026, the Company and the CLA Investors amended the Floor Price of the Promissory Notes to $ On April 15, 2026, the Company and the CLA Investors amended the Floor Price (as defined below) of the Promissory Notes to $
|
| On April 30, 2026, the Company and the CLA Investors entered into an amendment to the SPAs pursuant to which the Initial Subscription Amount was increased by $ |
| The conversions of the Promissory Notes triggered an adjustment to the exercise price and the number of warrant shares issuable pursuant to the April 2023 Warrants, September 2023 Warrants and January 2024 Warrants. The new exercise price of the warrants is $ |
Finance expense on the First and Second
Initial Promissory Notes during the period ended April 30, 2026 amounted to $
Management has elected to designate the instrument at fair value through
profit or loss under IFRS 9.4.3.5 at initial recognition for the Company’s promissory notes and therefore, the Company measures
the entire hybrid contract (host and variable conversion feature) at Fair Value Through Profit or Loss (FVTPL). No embedded derivative
is separated under IFRS 9 and no amortized-cost accounting or effective interest method applies.
| Convertible loans | ||||
| Balance, October 31, 2024 | $ | - | ||
| Proceeds received from issuance of convertible loans | ||||
| Finance expenses | ||||
| Issuance of shares upon conversion of convertible loans | ( | ) | ||
| Balance, October 31, 2025 | $ | |||
| Proceeds received from issuance of convertible loans | ||||
| Finance expenses | ||||
| Issuance of shares upon conversion of convertible loans | ( | ) | ||
| Balance, April 30, 2026 | $ | - | ||
F-11
CLEARMIND MEDICINE INC.
Notes to the Condensed Interim Consolidated Financial Statements
(Expressed in United States Dollars)
(Unaudited)
| 7. | Share Capital |
| a. | The Company’s authorized share capital comprises an unlimited common shares without par value. As of April 30, 2026, |
| b. | On December 15, 2025, the Company effected a |
| c. | Share transactions during the six months ended April 30, 2026: |
| (i) | During November 2025, the Promissory Notes were converted into |
| (ii) | On November 13, 2025, the Company entered into a securities purchase agreement with investors for the purchase and sale of (i) |
On November 17, 2025, the Company entered
into a securities purchase agreement with investors for the purchase and sale of (i)
On November 19, 2025, the Company entered
into a securities purchase agreement with investors for the purchase and sale of
On November 26, 2025, the Company entered
into a securities purchase agreement with investors for the purchase and sale of (i)
On December 3, 2025, the Company entered
into a securities purchase agreement with investors for the purchase and sale of
| (iii) | On November 14, 2025, April 2023 Warrants and January 2024 Warrants were exercised into |
| (iv) | On November 24, 2025, the Company issued |
| (v) | On February 2, 2026, the Company issued |
| (vi) | On April 20, 2026, |
| (vii) | On April 20, 2026, |
| (viii) | On April 21, 2026, January 2024 Warrants were exercised into
|
| (ix) | During February and April 2026, the CLA Investors converted
Promissory Notes in the aggregate amount of $ |
F-12
CLEARMIND MEDICINE INC.
Notes to the Condensed Interim Consolidated Financial Statements
(Expressed in United States Dollars)
(Unaudited)
| 8. | Warrants |
| a. |
| Number of warrants | ||||
| Balance, October 31, 2024 | ||||
| Exercise of warrants | ( | ) | ||
| Expiration of warrants | ( | ) | ||
| Balance, October 31, 2025 | ||||
| Number of shares to be issued from the exercise of these warrants, October 31, 2025 | ||||
| Balance, October 31, 2025 | ||||
| Exercise of warrants | ( | ) | ||
| Balance, April 30, 2026 (*) | ||||
| Number of shares to be issued from the exercise of these warrants | ||||
| (*) |
| b. |
| Number of warrants outstanding | Number of shares to be issued from the exercise of warrants (warrant shares) | Exercise price per warrant shares | Exercise price per warrant shares (USD) | Expiry date | ||||||||||||
| C $ | | $ | ||||||||||||||
| $ | $ | |||||||||||||||
| $ | $ | |||||||||||||||
| $ | $ | |||||||||||||||
F-13
CLEARMIND MEDICINE INC.
Notes to the Condensed Interim Consolidated Financial Statements
(Expressed in United States Dollars)
(Unaudited)
| 9. | Stock Options |
| a. | On January 6, 2025, the shareholders of the Company approved the Company’s Omnibus Equity Incentive Plan, (the “Omnibus Plan”). Pursuant to the Omnibus Plan, the Company is authorized to grant options or RSUs to officers, directors, employees and consultants enabling them to acquire, together with” Options”, “Awards” or “Stock Options” as defined, up to |
The maximum number of common shares
reserved for issuance in any
| b. | As of April 30, 2026, there are |
| c. | The portion of the total fair value of stock options expensed during
the six months ended April 30, 2026, was $Nil (three and six months ended April 30, 2025 $nil and $ |
F-14
CLEARMIND MEDICINE INC.
Notes to the Condensed Interim Consolidated Financial Statements
(Expressed in United States Dollars)
(Unaudited)
| 10. | Restricted Share Units |
| a. | The Company is able to grant RSUs pursuant to the Omnibus Plan to its directors, officers, employees, and consultants. Each RSU is equivalent in value to a common share and upon vesting results in the holder thereof being issued, at the discretion of the Board, either (i) a common share, or (ii) an amount of cash equal to the fair market value of a common share. |
| b. |
| Number of RSUs | Weighted average issue price (C$) | Weighted average issue price (USD$) | ||||||||||
| Balance, October 31, 2024 | $ | $ | ||||||||||
| Granted | ||||||||||||
| Exercised | ( | ) | ||||||||||
| Balance, October 31, 2025 | $ | $ | ||||||||||
| Granted (i) | ||||||||||||
| Exercised | ( | ) | ||||||||||
| Balance, April 30, 2026 | $ | $ | ||||||||||
| (i) |
| 11. | Financial Instruments and Risk Management |
| a. |
| Fair Value Measurements Using | ||||||||||||||||
| Quoted prices in active markets for identical instruments (Level 1) | Significant other observable inputs (Level 2) | Significant unobservable inputs (Level 3) | Balance April 30, 2026 | |||||||||||||
| Short-term investment- Polyrizon shares | $ | $ | – | $ | – | $ | ||||||||||
| Short-term investment- Taurus shares | – | – | ||||||||||||||
| Short-term investment- Taurus Warrants | – | – | ||||||||||||||
| Short-term investment- QXL Shares | – | – | ||||||||||||||
| Short-term investment- QXL Warrants | – | – | ||||||||||||||
| Derivative warrant liabilities | – | – | ( | ) | ( | ) | ||||||||||
F-15
CLEARMIND MEDICINE INC.
Notes to the Condensed Interim Consolidated Financial Statements
(Expressed in United States Dollars)
(Unaudited)
| 11. | Financial Instruments and Risk Management (continued) |
Assets and liabilities measured at fair value on a recurring basis were presented in the Company’s statement of financial position as of October 31, 2025, as follows:
| Fair Value Measurements Using | ||||||||||||||||
| Quoted prices in active markets for identical instruments (Level 1) | Significant other observable inputs (Level 2) | Significant unobservable inputs (Level 3) | Balance October 31, 2025 | |||||||||||||
| Short-term investment- Polyrizon shares | $ | $ | – | $ | – | $ | ||||||||||
| Short-term investment- Taurus shares | – | – | ||||||||||||||
| Short-term investment- Taurus Warrants | – | – | ||||||||||||||
| Convertible loans | – | ( | ) | – | ( | ) | ||||||||||
| Derivative warrant liabilities | – | – | ( | ) | ( | ) | ||||||||||
The fair value of other assets and liabilities, which include cash, amounts receivable, accounts payable and accrued liabilities, and amounts due to related parties, approximate their carrying values due to the relatively short-term maturity of these instruments.
| b. | Credit Risk |
Financial instruments that potentially subject the Company to a concentration of credit risk consist primarily of cash and cash equivalents. The Company limits its exposure to credit loss by placing its cash with high credit quality financial institutions. The carrying amount of financial assets represents the maximum credit exposure.
| c. | Foreign Exchange Rate Risk |
Foreign currency risk is the risk that the fair value of future cash flows of a financial instrument will fluctuate due to changes in foreign exchange rates. The Company is exposed to foreign currency risk to the extent that monetary assets and liabilities are denominated in a foreign currency. The Company’s Israeli subsidiary operates in Israel and has certain monetary financial instruments denominated in New Israeli Shekel and Canadian Dollars. The Company has not entered into foreign exchange rate contracts to mitigate this risk.
The following table indicates the impact
of foreign currency exchange risk on net working capital as of April 30, 2026. The table below also provides a sensitivity analysis of
a
| Cash and cash equivalents | $ | |||
| Other receivables | ||||
| Accounts payable and accrued liabilities | ( | ) | ||
| Due to related parties | ( | ) | ||
| Total foreign currency financial assets and liabilities | $ | |||
| Impact of a | $ |
F-16
CLEARMIND MEDICINE INC.
Notes to the Condensed Interim Consolidated Financial Statements
(Expressed in United States Dollars)
(Unaudited)
| 11. | Financial Instruments and Risk Management (continued) |
| d. | Interest Rate Risk |
Interest rate risk is the risk that the fair value of future cash flows of a financial instrument will fluctuate because of changes in market interest rates. The fair value of the derivative warrant liabilities can fluctuate depending on the fluctuation in the risk-free interest rate.
| e. | Liquidity Risk |
Liquidity risk is the risk that the Company will not be able to meet its financial obligations as they fall due. The Company’s objective to managing liquidity risk is to ensure that it has sufficient liquidity available to meet its liabilities when due. The Company relies on raising debt or equity financing in a timely manner.
The following amounts are the contractual maturities of financial liabilities as of April 30, 2026 and October 31, 2025:
| April 30, 2026 | Total | Within 1 year | Within 2-5 years | |||||||||
| Accounts payable and accrued liabilities | $ | $ | $ | – | ||||||||
| Due to related parties | – | |||||||||||
| Lease liability | ||||||||||||
| $ | $ | $ | ||||||||||
| October 31, 2025 | Total | Within 1 year | Within 2-5 years | |||||||||
| Accounts payable and accrued liabilities | $ | $ | $ | – | ||||||||
| Due to related parties | – | |||||||||||
| Lease liability | – | |||||||||||
| Convertible loans | ||||||||||||
| $ | $ | $ | – | |||||||||
| 12. | Capital Management |
The Company manages its capital to maintain its ability to continue as a going concern and to provide returns to shareholders and benefits to other stakeholders. The capital structure of the Company consists of cash and equity comprised of issued share capital and share premium, warrants and share-based payment reserve.
The Company manages its capital structure and makes adjustments to it in light of economic conditions. The Company, upon approval from its Board, will balance its overall capital structure through new share issuances or by undertaking other activities as deemed appropriate under the specific circumstances.
The Company is not subject to externally imposed capital requirements and the Company’s overall strategy with respect to capital risk management remains unchanged from the six months ended April 30, 2026.
F-17
CLEARMIND MEDICINE INC.
Notes to the Condensed Interim Consolidated Financial Statements
(Expressed in United States Dollars)
(Unaudited)
| 13. | Segmented Information |
As of April 30, 2026, the Company has
| 14. | Commitments |
| a. | On December 19, 2022, the Company entered into a license agreement with Yissum Research Development Company of the Hebrew University of Jerusalem, which provides the Company with an exclusive, perpetual, worldwide and sublicensable license to use the joint patents that the Company have with Yissum to further develop, manufacture and commercialize products for innovative treatment in the relevant fields such as metabolic syndrome and anti-obesity (the “Yissum Metabolic Syndrome License Agreement”). According to the Yissum Metabolic Syndrome License Agreement, the Company shall pay Yissum royalties at the rate of |
| b. | On January 15, 2024, the Company entered into a license agreement with BIRAD, the research and development company of Bar-Ilan University, which provides the Company with an exclusive, perpetual, worldwide and sublicensable license to use the joint patent that the Company has with BIRAD, to further develop, manufacture and commercialize products for innovative treatment of cocaine addiction (“the BIRAD License Agreement”). According to the BIRAD License Agreement, the Company shall pay BIRAD royalties at the rate of |
| c. | On March 19, 2024, the Company entered into a second license agreement with Yissum Research Development Company of the Hebrew University of Jerusalem, which provides to the Company with an exclusive, perpetual, worldwide and sublicensable license to use the Yissum’s patent titled “Psychedelic compounds, methods of their preparation and uses thereof” to further develop, manufacture, and commercialize innovative compounds targeted at treating post-traumatic stress disorder and other health conditions (the “Yissum PTSD License Agreement”). According to the Yissum PTSD License Agreement, the Company is required to pay Yissum annual maintenance fees ranging from $ |
F-18
CLEARMIND MEDICINE INC.
Notes to the Condensed Interim Consolidated Financial Statements
(Expressed in United States Dollars)
(Unaudited)
| 14. | Commitments (continued) |
| d. | On March 31, 2024, the Company entered into a third license agreement with Yissum Research Development Company of the Hebrew University of Jerusalem, which provides to the Company with an exclusive, perpetual, worldwide and sublicensable license to use Yissum’s patent “Psychoactive compounds, methods of their preparation and uses thereof in the treatment of mental disorders” to further develop, manufacture, and commercialize innovative compounds targeted at Generation 3.0 psychedelic compounds for the treatment of mental disorders (the “Yissum Psychedelic License Agreement”). According to the Yissum Psychedelic License Agreement, the Company is required to pay Yissum annual maintenance fees ranging from $ | |
| e. | On June 13, 2024, the Company entered into an agreement with a third party for the lease of office space in Tel Aviv, Israel, having a total area of approximately |
| 15. | Subsequent Events |
| a. | On May 1, 2026, the CLA Investors purchased additional Promissory
Notes in the aggregate principal amount of $ |
| b. | On May 21, 2026, the Company effected a reverse share split of the Company’s common shares at the ratio of |
| c. | On June 1, 2026, the CLA Investors purchased additional Promissory Notes in the aggregate
principal amount of $ |
F-19
Exhibit 99.2
CLEARMIND MEDICINE INC.
MANAGEMENT’S DISCUSSION AND ANALYSIS
For the Three and Six Months Ended April 30, 2026
(Expressed in United States Dollars)
CLEARMIND MEDICINE INC.
Management’s Discussion and Analysis
For the Three and Six Months Ended April 30, 2026
This Management’s Discussion and Analysis (“MD&A”) of Clearmind Medicine Inc. (“Clearmind” or the “Company”), prepared as of June 15, 2026, should be read in conjunction with the unaudited condensed interim consolidated financial statements and the notes thereto for the three and six months ended April 30, 2026, which were prepared in accordance with International Financial Reporting Standards (“IFRS”). All amounts are expressed in United States dollars unless otherwise indicated.
Additional information about the Company is available on SEDAR at www.sedar.com.
Cautionary Statement Regarding Forward-Looking Information
This MD&A may contain “forward-looking statements” which reflect the Company’s current expectations regarding future results of operations, performance and achievements of the Company. The Company has tried, wherever possible, to identify these forward-looking statements by, among other things, using words such as “anticipate,” “believe,” “estimate,” “expect” and similar expressions. The statements reflect the current beliefs of the management of the Company and are based on currently available information. Accordingly, these statements are subject to known and unknown risks, uncertainties and other factors, which could cause the actual results, performance, or achievements of the Company to differ materially from those expressed in, or implied by, these statements.
The Company undertakes no obligation to publicly update or review the forward-looking statements whether as a result of new information, future events or otherwise.
Historical results of operations and trends that may be inferred from the following discussions and analysis may not necessarily indicate future results from operations.
Description of Business and Company Overview
Corporate Information
The Company was incorporated in the province of British Columbia on July 18, 2017. The Company is a clinical stage pharmaceutical company currently engaged in phase I/IIa clinical trials of novel psychedelic medicines that have been developed to solve widespread, yet under-served, health problems. The Company’s head office is located at Suite 101 -1220 West 6th Avenue, Vancouver, BC, V6H 1A5. The Company’s wholly-owned Israeli subsidiary (Clearmindmed Ltd.) functions as the research and development arm of the Company. and The Company’s wholly-owned Canadian subsidiary, Clearmind Labs Corp., holds part of the groups IP, and the Company’s wholly-owned Canadian subsidiary, Clearmind Buzz Inc., which was incorporated in Ontario, Canada on March 18, 2026, and currently inactive.
On November 14, 2022, the Company completed a listing on the Nasdaq Capital Market (“Nasdaq”)and trades under the symbol “CMND”. The Company was listed on the Canadian Securities Exchange (“CSE”) in Toronto until March 14, 2024. Following approval for a voluntary delisting, the Company no longer trades on the CSE but remains a reporting issuer in Canada.
On May 21, 2026, the Company effected a 1-for-10 reverse split of its issued and outstanding common shares. Following the reverse split, holders of the Company’s common shares received 0.025 of a common share for every one common share held. All share amounts have been retroactively restated for all periods presented.
Company Overview
The Company is a clinical stage neuroplastogens pharmaceutical biotech company focused on the discovery and development of non-hallucinogenic, second generation, neuroplastogen-derived therapeutics to solve widespread and underserved health problems, which is currently engaged in phase I/IIa clinical trials . The Company’s goal is to develop and provide a new type of treatment for mental health disorders, including Alcohol Use Disorder (“AUD”), binge drinking and eating disorders, where there is significant unmet need and lack of innovation. The Company sees psychedelic therapies, which previously may have been overlooked or underused, as the future of treatment for a variety of indications. The Company believes that its solution for AUD can help solve one of the world’s biggest health problems, which costs the United States alone roughly $250 billion each year.
The Company’s flagship treatment and initial focus is on AUD, which is incredibly common. It varies from mild to excessive and describes a person’s inability to restrict their alcohol consumption, despite negative social, occupational, or health consequences. Alcohol consumption contributes to 3 million deaths each year globally and is the third most common preventable cause of death in the United States. In January 2025, the U.S. Surgeon General released a new Surgeon General’s Advisory on Alcohol and Cancer Risk, outlining the direct link between alcohol consumption and increased cancer risk, which is in addition to other common risks associated with excessive alcohol consumption. Apart from potentially changing people’s lives, the Company believes that its treatment could potentially reduce the amount currently being spent on the consequences of AUD in the United States, Europe, India, China and other countries around the world. The Company also believes that its treatment may address binge drinking. 178,000 people die every year in the United States alone due to excessive alcohol use.
The Company has also advanced its proprietary 5-Methoxy-2-aminoindane (“MEAI”)-based alcohol substitute beverage program by completing most of the pre-clinical studies required for a novel-food application submission according to novel foods and food additives legislation and regulations accepted in many jurisdictions worldwide and entering into a strategic agreement to source global manufacturers and distributors for its MEAI-based alcohol substitute beverages.
2
CLEARMIND MEDICINE INC.
Management’s Discussion and Analysis
For the Three and Six Months Ended April 30, 2026
The Company has completed a series of pre-clinical, investigational new drug-enabling studies in the United States and China that are required before it can study its compound for the first time in humans. These studies include pharmacokinetic and toxicological studies in rats and dogs in order to assess the safety profile of our compound and characterization of the drug metabolism. The Company has conducted several metabolism studies designed to better understand the way MEAI is digested in several species. In addition, the Company has conducted a pre-clinical animal model of AUD to characterize the effect of MEAI on alcohol consumption. This study involved testing the effect of MEAI’s ability to curb alcohol cravings after exposing mice to prolonged alcohol consumption over a short period, mimicking binge alcohol consumption in humans.
In February 2024 and in July 2024, the Company announced that it wase granted approval by the Israeli Ministry of Health and by the U.S. Food and Drug Administration, respectively to initiate its first-in-human Phase I/IIa clinical trial with CMND-100 in patients suffering from AUD. Subsequently, in May 2023, the Company initiated the CM-CMND-001 clinical trial in both Israel and the United States, including at the Yale School of Medicine’s Department of Psychiatry and Johns Hopkins University School of Medicine. In October 2024 and December, the Company announced that it received IRB approvals from Johns Hopkins University and Yale University, respectively, its clinical sites for part A of its Phase I/IIa clinical trial in the United States for treating patients suffering from AUD. In July 2025, the Company announced site initiation at Tel Aviv Sourasky Medical Center (TASMC) in Israel and in August 2025, the Company receipt of TASMC IRB approval. In addition, the Company announced in August 2025 IRB approval at Hadassah Medical Center in Israel and in November 2025, the Company announced initiation of this site.
Significant developments during the period
In November 2025, the Company’s independent Data and Safety Monitoring Board (“DMSB”) unanimously approved the continuation of the Phase I/IIa clinical trial for CMND-100 following a positive interim safety review that found that there were no serious adverse events reported, there was general good tolerability across all participants and there was strong treatment observance, with high adherence to the dosing regimen and study protocol. The DSMB, which is comprised of independent experts, including specialists in psychiatry, a biostatistician and a neuropsychopharmacologist, conducted a thorough review of unblinded safety data from the initial dosing cohort.
In March 2026, the company's independent DSMB has completed the second scheduled interim review of the Company’s ongoing FDA-approved Phase I/IIa clinical trial for CMND-100, and that based on the encouraging additional top-line data from the second cohort, which demonstrated a favorable safety profile, the DSMB recommended that the clinical trial continue.
In April 2026 the company's independent DSMB has completed its third review and issued again a positive recommendation to continue the ongoing FDA-approved Phase I/IIa clinical trial of CMND-100 for the treatment of Alcohol Use Disorder (“AUD”).
As a result, the Company will now proceed to the fourth cohort of the trial and will increase the tested dose of its proprietary drug candidate CMND-100 to 160mg.
The Phase I part of the Phase I/IIa clinical study is an open label, randomized study to evaluate the safety and pharmacokinetics of single ascending doses of MEAI oral capsules. In the study we are utilizing a hybrid model where we study the effects of MEAI in healthy volunteers and AUD patients. Single ascending doses will be distributed in 4 cohorts, with 6 subjects per dose. As the study moves forward, we will determine the distribution of the cohorts based, among other things, on the rate in which we can enroll patients at each site.
The Phase IIa part of the Phase I/IIa clinical study is a double-blind, randomized, placebo-controlled study to assess the safety of multiple doses of MEAI in healthy volunteers and AUD subjects and as a secondary endpoint, the potential effect of MEAI on drinking patterns and cravings in individuals with AUD in accordance with DSM-V criteria. Two cohorts of 18 subjects per cohort will be given the highest tolerated doses and placebo (2:1 ratio). Oral capsules will be given once daily, for five consecutive days. The patients will complete diaries and questionnaires to report on their drinking patterns and craving for alcohol during the clinical trial period.
The Company uses a Pharmacokinetics (“PK”) assessment in both phases of the Phase I/IIa study. PK is defined by the American Society of Health-System Pharmacists as the study of the time course of a drug absorption, distribution, metabolism, and excretion in animals and human. Typical PK assessments include blood and organs collections at standard time intervals in order to test the drug level in the various tissues as function of time. The pharmacokinetic information as studied in animals has application to the safe and effective therapeutic management of drugs in an individual patient. In our study, our PK assessment will consist of collecting blood from all subjects enrolled in the study at the following timepoints:
| (i) | Phase 1 - before dosing and at multiple time points (at 0.25, 0.5, 1.0, 2.0, 4.0, 6.0, 8.0, 12.0, 18.0 and 24-hour post drug administration. |
| (ii) | Phase 2 - before the first dosing and at multiple time points (at 0.25, 0.5, 1.0, 2.0, 4.0, 6.0, 8.0, 12.0, 18.0 and, 24-hour post drug administration and before the last dosing and at multiple time points (at 0.25, 0.5, 1.0, 2.0, 4.0, 6.0, 8.0, 12.0, 18.0 and, 24-hour post last drug administration. |
3
CLEARMIND MEDICINE INC.
Management’s Discussion and Analysis
For the Three and Six Months Ended April 30, 2026
Prior Use of Proceeds Disclosure
The table below describes the difference between the Company’s anticipated use of proceeds from public offerings completed since November 2022, as disclosed in previous news releases. The table shows the amounts actually spent for the period from November 1, 2022, through to April 30, 2026. The variances noted below do not have a material impact on the Company’s ability to achieve its business objectives and milestones. The table below does not include proceeds received from the exercise of warrants.
| Use of Available Funds | Disclosure Regarding Use of Proceeds (USD) |
Spent through to April 30, 2026 (USD) | ||
| November 2022 public offering: | ||||
| To advance the formulation and clinical development efforts in our MEAI patented compounds (completed); | 1.5 million | 1.5 million | ||
| To complete the pre-IND enabling studies and IND submission (completed) | 1.0 million | 1.0 million | ||
| To complete planned Phase I/IIa studies | 3.5 million | 3.0 million | ||
| The remainder for working capital and general corporate purposes and possible in-licensing of intellectual property for new product candidates | 0.4 million | 0.4 million | ||
| April 2023 Public Offering | ||||
| General corporate purposes, which may include operating expenses, research and development, including clinical and pre-clinical testing of our product candidates, working capital, future acquisitions and general capital expenditures | 2.9 million | 2.9 million | ||
| September 2023 Public Offering | ||||
| For general corporate purposes, which may include operating expenses, research and development, including clinical and pre-clinical testing of its product candidates, working capital, future acquisitions and general capital expenditures. | 2.25 million | 2.25 million | ||
| January 2024 Public Offering and Concurrent Private Placement | ||||
| For general corporate purposes and working capital. | 2.4 million | 2.4 million | ||
| September and October 2025 Convertible Notes Securities Purchase Agreement | ||||
| Working capital and general corporate purposes, as well as for potential acquisitions to support its exploration of strategic opportunities | 2.25 million | 1.5 million | ||
| November and December 2025 Public Offering | ||||
| Working capital and general corporate purposes, as well as for potential acquisitions to support its exploration of strategic opportunities | 7.2 million | 1.5 million | ||
| March and April 2026 Convertible Notes Securities Purchase Agreement | ||||
| Working capital and general corporate purposes, as well as for potential acquisitions to support its exploration of strategic opportunities | 4.545 million | - |
4
CLEARMIND MEDICINE INC.
Management’s Discussion and Analysis
For the Three and Six Months Ended April 30, 2026
Selected Financial Information
The following financial data prepared in accordance with IFRS in United States dollars is presented for the three and six months ended April 30, 2026 and 2025.
| Three months ended | Six months ended | |||||||||||||||
| April 30, | April 30, | |||||||||||||||
| 2026 | 2025 | 2026 | 2025 | |||||||||||||
| Operating expenses | ||||||||||||||||
| General and administrative | $ | 924,502 | $ | 855,124 | $ | 3,943,923 | $ | 1,889,860 | ||||||||
| Research and development, net | 646,707 | 451,857 | 1,287,201 | 913,295 | ||||||||||||
| Total operating expenses | 1,571,209 | 1,306,981 | 5,231,124 | 2,803,155 | ||||||||||||
| Finance income (expenses) | ||||||||||||||||
| Changes in fair value of derivative warrant liabilities | (452,435 | ) | 664,768 | (86,509 | ) | 1,179,518 | ||||||||||
| Changes in fair value of short-term investments | 438,021 | (157,083 | ) | (134,948 | ) | (228,788 | ) | |||||||||
| Foreign exchange gain | 8,489 | 2,246 | 14,751 | (2,204 | ) | |||||||||||
| Other finance expenses | (4,233 | ) | (7,868 | ) | (8,340 | ) | (16,583 | ) | ||||||||
| Interest income on deposits | 42,025 | 41,648 | 106,674 | 75,656 | ||||||||||||
| Changes in fair value of convertible loans | (505,000 | ) | - | (555,469 | ) | - | ||||||||||
| Total finance income | (473,133 | ) | 543,711 | (663,841 | ) | 1,007,599 | ||||||||||
| Loss before taxes | (2,044,342 | ) | (763,270 | ) | (5,894,965 | ) | (1,795,556 | ) | ||||||||
| Tax expenses | (3,311 | ) | (20,658 | ) | (7,271 | ) | (59,993 | ) | ||||||||
| Net Loss and Comprehensive loss | $ | (2,047,653 | ) | $ | (783,928 | ) | $ | (5,902,236 | ) | $ | (1,855,549 | ) | ||||
| Loss per share, basic and diluted | $ | (6.78 | ) | $ | (62.27 | ) | $ | (28.43 | ) | $ | (156.01 | ) | ||||
| Weighted average number of shares outstanding for the purposes of basic and diluted loss per share | 301,964 | 12,589 | 207,586 | 11,894 | ||||||||||||
Three-month period ended April 30, 2026, compared to the three-month period ended April 30, 2025
General and Administrative Expenses
For the three-month period ended April 30, 2026, general and administrative expenses amounted to $924,502 as compared to $855,124 for the three-month period ended April 30, 2025. The increase in 2026 relates primarily to an increase in professional fees.
Research Costs
Research costs are comprised primarily of (i) pre-clinical trials and (ii), professional regulatory and other expenses.
For the three-month period ended April 30, 2026, research costs amounted to $646,707 as compared to $451,857 for the three-month period ended April 30, 2025.
During the mentioned period, most of our R&D activity revolved around our clinical trial as discussed herein.
5
CLEARMIND MEDICINE INC.
Management’s Discussion and Analysis
For the Three and Six Months Ended April 30, 2026
Finance income (expenses)
For the three-month period ended April 30, 2026, financial expenses amounted to $(473,133) as compared to financial income of $543,711 for the three-month period ended April 30, 2025. The financial expenses during the three-month period ended April 30, 2026, consists of change in warrant liability of $(452,435), changes in fair value of short-term investments of $438,021, foreign exchange gain of $8,489, other finance expenses of $(4,233), interest income on deposits of $42,025 and changes in fair value of convertible loans of ($505,000).
Loss for the period
The Company reported a loss for the three-month period ended April 30, 2026, of $2,047,653 as compared to a loss of $783,928 for the three-month period ended April 30, 2025.
Six-month period ended April 30, 2026, compared to the six-month period ended April 30, 2025
General and Administrative Expenses
For the six-month period ended April 30, 2026, general and administrative expenses amounted to $3,943,923 as compared to $1,889,860 for the six-month period ended April 30, 2025. The increase in 2026 relates primarily to an increase in professional fees, investor relations and share-based compensation.
Research Costs
Research costs are comprised primarily of (i) pre-clinical trials and (ii), professional regulatory and other expenses.
For the six-month period ended April 30, 2026, research costs amounted to $1,287,201 as compared to $913,295 for the six -month period ended April 30, 2025.
During the mentioned period, most of our R&D activity revolved around our clinical trial.
Finance income (expenses)
For the six-month period ended April 30, 2026, financial expenses amounted to $(663,841) as compared to financial income of $1,007,599 for the six-month period ended April 30, 2025. The financial expenses during the six-month period ended April 30, 2026, consists of change in warrant liability of $(86,509), changes in fair value of short-term investments of $(134,948), foreign exchange gain of $14,751, changes in fair value of convertible loans of $(555,469), other finance expenses of $(8,340) and interest income on deposit of $106,674.
Loss for the period
The Company reported a loss for the six-month period ended April 30, 2026, of $5,902,236 as compared to a loss of $1,855,549 for the six-month period ended April 30, 2025.
Financial Summary of Quarterly Results
The following is a summary of the Company’s financial results for the eight most recently completed quarters.
| April 30, 2026 | January 31, 2026 | October 31, 2025 | July 31, 2025 | |||||||||||||
| Total revenues | $ | – | $ | – | $ | – | $ | – | ||||||||
| Net loss | (2,047,653 | ) | (3,854,583 | ) | (687,842 | ) | (1,313,592 | ) | ||||||||
| Net loss per share, basic and diluted | (6.78 | ) | (22.65 | ) | (47.35 | ) | (98.36 | ) | ||||||||
| April 30, 2025 | January 31, 2025 | October 31, 2024 | July 31, 2024 | |||||||||||||
| Total revenues | $ | – | $ | – | $ | – | $ | – | ||||||||
| Net loss | (783,928 | ) | (1,071,621 | ) | (884,744 | ) | (2,093,917 | ) | ||||||||
| Net loss per share, basic and diluted | (62.27 | ) | (93.74 | ) | (29.50 | ) | (235.28 | ) | ||||||||
The loss per quarter and related net loss per share is a function of the level of research and development activity that took place during that quarter.
6
CLEARMIND MEDICINE INC.
Management’s Discussion and Analysis
For the Three and Six Months Ended April 30, 2026
Liquidity and Capital Resources
As of April 30, 2026, the Company had cash on hand of $11,415,719 and working capital of $11,334,370, compared to $3,923,058 and working capital of $1,057,262 as of October 31, 2025, respectively. During the six-month period ended April 30, 2026, the Company’s overall position of cash increased by $7,492,661 from the year ended October 31, 2025. This increase in cash can be attributed to the following:
| ● | The Company’s net cash used in operating activities during the six-month period ended April 30, 2026, was $3,853,029 as compared to $2,363,833 for the six-month period ended April 30, 2025. This increase is mostly due to an increase in the net loss for the period. |
| ● | Net cash used in investing activities was $650,001 for the six -month period ended April 30, 2026, as compared to $130,538 for the six-month period ended April 30, 2025. cash used in investing activities in 2026 was from acquisition of short-term investment. |
| ● | Net cash provided from financing activities for the six-month period ended April 30, 2026, was $11,995,163 as compared to $394,514 for the six-month period ended April 30, 2025. Cash provided in 2026 was from exercise of warrants and proceeds received from issuance of shares and proceeds received from convertible loans. |
The Company anticipates that its cash and cash equivalents will provide sufficient liquidity for at least twelve months, however, the Company may have capital requirements in excess of its currently available resources in order to advance all of its programs. The actual amount of cash that the Company will need to operate is subject to many factors, including, but not limited to, the timing, design and conduct of clinical trials. The Company is dependent upon significant future financing to provide the cash necessary to execute its current operations, including the possible future commercialization of any of its drug candidates, subject to regulatory approval.
In the event the Company’s plans change, its assumptions change or prove inaccurate, or its capital resources in addition to projected cash flow, if any, prove to be insufficient to fund operations, the Company may be required to seek additional financing. There can be no assurance that the Company will have sufficient financing to meet its future capital requirements or that additional financing will be available on terms acceptable to the Company in the future.
Capital Management
The Company manages its capital to maintain its ability to continue as a going concern and to provide returns to shareholders and benefits to other stakeholders. The capital structure of the Company consists of cash and equity comprised of issued capital, shares issuable, warrants reserve and share-based payment reserve.
The Company manages its capital structure and makes adjustments to it in light of economic conditions. The Company, upon approval from its Board of Directors, will balance its overall capital structure through new share issuances or by undertaking other activities as deemed appropriate under the specific circumstances.
The Company is not subject to externally imposed capital requirements and the Company’s overall strategy with respect to capital risk management remains unchanged from the year ended October 31, 2025.
Off Balance Sheet Arrangements
There are no off-balance sheet arrangements to which the Company is committed.
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CLEARMIND MEDICINE INC.
Management’s Discussion and Analysis
For the Three and Six Months Ended April 30, 2026
Transactions With Related Parties
| a. | Compensation to key management personnel |
| (i) | The compensation to key management personnel for services they provide to the Company is as follows: |
| Three months ended | Three months ended | Six months ended | Six months ended | |||||||||||||
| April 30, | April 30, | April 30, | April 30, | |||||||||||||
| 2026 | 2025 | 2026 | 2025 | |||||||||||||
| Officers: | ||||||||||||||||
| Consulting fees | $ | 133,465 | $ | 84,557 | $ | 304,593 | $ | 168,557 | ||||||||
| Share based compensation | - | 43,973 | - | 117,902 | ||||||||||||
| $ | 133,465 | $ | 128,530 | $ | 304,593 | $ | 286,459 | |||||||||
| Directors: | ||||||||||||||||
| Directors’ fees | $ | 148,462 | $ | 58,127 | $ | 330,492 | $ | 116,333 | ||||||||
| Share based compensation | - | 69,226 | - | 186,821 | ||||||||||||
| $ | 148,462 | $ | 127,353 | $ | 330,492 | $ | 303,154 | |||||||||
| (ii) | Balances with related parties |
| April, | October 31, | |||||||
| 2026 | 2025 | |||||||
| Amounts owed to officers | $ | 46,708 | $ | 29,761 | ||||
| Amounts owed to directors | 51,093 | 30,471 | ||||||
| $ | 97,801 | $ | 60,232 | |||||
| b. | On March 7, 2022, the Company signed an agreement with SciSparc Ltd (“SciSparc”), pursuant to which the Company and SciSparc agreed to cooperate in conducting a feasibility study using certain molecules developed by each party (the “Cooperation Agreement”). Certain of the Company’s officers and directors currently operate, manage or are engaged as officers and/or directors of SciSparc. |
In June 2023, the Company entered into a research agreement with the Hebrew University of Jerusalem to evaluate it’s and SciSparc’s combination treatment for obesity and metabolic syndrome.
To date, the collaboration has resulted in the filing of nine patent applications. To the extent the parties determine to proceed to a commercial cooperation, they will enter into a joint venture where the parties share the economics and rights on a 50%-50% basis. To date, no determination has been made to pursue the joint venture and the development of the molecule remains in a very early stage.
For the three and six months ended April 30, 2026, the Company incurred research and development expenses conducted within the framework of the Cooperation Agreement in the amount of $88,847 and $121,815, respectively (three and six months ended April 30, 2025- $33,763 and $46,509 respectively). As of April 30, 2026, $405,315 is owed to the Company by SciSparc (October 31, 2025 - $286,488).
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CLEARMIND MEDICINE INC.
Management’s Discussion and Analysis
For the Three and Six Months Ended April 30, 2026
Financial Instruments and Risk Management
| (a) | Fair Values |
Assets and liabilities measured at fair value on a recurring basis were presented on the Company’s statement of financial position as of April 30, 2026, as follows:
| Fair Value Measurements Using | ||||||||||||||||
| Quoted prices in active markets for identical instruments (Level 1) | Significant other observable inputs (Level 2) | Significant unobservable inputs (Level 3) | Balance April 30, 2026 | |||||||||||||
| Short-term investment- Polyrizon shares | $ | 2,306 | $ | – | $ | – | $ | 2,306 | ||||||||
| Short-term investment- Taurus shares | 289,146 | – | – | 289,146 | ||||||||||||
| Short-term investment- Taurus Warrants | – | – | 67,464 | 67,464 | ||||||||||||
| Short-term investment- QXL Shares | 1,155,144 | – | – | 1,155,144 | ||||||||||||
| Short-term investment- QXL Warrants | – | – | 663,400 | 663,400 | ||||||||||||
| Derivative warrant liabilities | – | – | (2,135,753 | ) | (2,135,753 | ) | ||||||||||
Assets and liabilities measured at fair value on a recurring basis were presented on the Company’s statement of financial position as of October 31, 2025, as follows:
| Fair Value Measurements Using | ||||||||||||||||
| Quoted prices in active markets for identical instruments (Level 1) | Significant other observable inputs (Level 2) | Significant unobservable inputs (Level 3) | Balance October 31, 2025 | |||||||||||||
| Short-term investment- Polyrizon shares | $ | 886 | $ | – | $ | – | $ | 886 | ||||||||
| Short-term investment- Taurus shares | 1,030,402 | – | – | 1,030,402 | ||||||||||||
| Short-term investment- Taurus warrants | – | – | 631,119 | 631,119 | ||||||||||||
| Convertible loans | – | (1,760,066 | ) | – | (1,760,066 | ) | ||||||||||
| Derivative warrant liabilities | – | – | (2,369,195 | ) | (2,369,195 | ) | ||||||||||
The fair values financial instruments, which include cash, amounts receivable, accounts payable and accrued liabilities, and amounts due to related parties, approximate their carrying values due to the relatively short-term maturity of these instruments.
| (b) | Credit Risk |
Financial instruments that potentially subject the Company to a concentration of credit risk consist primarily of cash. The Company limits its exposure to credit loss by placing its cash with high credit quality financial institutions. The carrying amount of financial assets represents the maximum credit exposure.
| (c) | Foreign Exchange Rate Risk |
Foreign currency risk is the risk that the fair value of future cash flows of a financial instrument will fluctuate due to changes in foreign exchange rates. The Company is exposed to foreign currency risk to the extent that monetary assets and liabilities are denominated in a foreign currency. The Company’s subsidiary operates in Israel and has certain monetary financial instruments denominated in New Israeli Shekel and CAD. The Company has not entered into foreign exchange rate contracts to mitigate this risk.
9
CLEARMIND MEDICINE INC.
Management’s Discussion and Analysis
For the Three and Six Months Ended April 30, 2026
The following table indicates the impact of foreign currency exchange risk on net working capital as at April 30, 2026. The table below also provides a sensitivity analysis of a 10% strengthening of the foreign currency against functional currencies identified which would have increased (decreased) the Company’s net loss by the amounts shown in the table below. A 10% weakening of the foreign currency against the functional currencies would have had the equal but opposite effect as of April 30, 2026.
| Cash and cash equivalents | $ | 229,398 | ||
| Other receivables | 142,560 | |||
| Accounts payable and accrued liabilities | (132,648 | ) | ||
| Due to related parties | (69,801 | ) | ||
| Total foreign currency financial assets and liabilities | $ | 169,509 | ||
| Impact of a 10% strengthening or weakening of foreign exchange rate | $ | 16,951 |
| (d) | Interest Rate Risk |
Interest rate risk is the risk that the fair value of future cash flows of a financial instrument will fluctuate because of changes in market interest rates. The Company is not exposed to significant interest rate risk as it does not have any liabilities with variable rates.
| (e) | Liquidity Risk |
Liquidity risk is the risk that the Company will not be able to meet its financial obligations as they fall due. The Company’s objective to managing liquidity risk is to ensure that it has sufficient liquidity available to meet its liabilities when due. The Company relies on raising debt or equity financing in a timely manner.
The following amounts are the contractual maturities of financial liabilities as of April 30, 2026, and October 31, 2025:
| April 30, 2026 | Total | Within 1 year | Within 2-5 years | |||||||||
| Accounts payable and accrued liabilities | $ | 713,629 | $ | 713,629 | $ | – | ||||||
| Due to related parties | 97,801 | 97,801 | – | |||||||||
| Lease liability | 85,588 | 41,241 | 44,347 | |||||||||
| $ | 897,018 | $ | 852,671 | $ | 44,347 | |||||||
| October 31, 2025 | Total | Within 1 year | Within 2-5 years | |||||||||
| Accounts payable and accrued liabilities | $ | 682,163 | $ | 682,163 | $ | – | ||||||
| Due to related parties | 60,232 | 60,232 | – | |||||||||
| Lease liability | 18,800 | 18,800 | – | |||||||||
| Convertible loans | 1,760,066 | 1,760,066 | ||||||||||
| $ | 2,521,261 | $ | 2,521,261 | $ | – | |||||||
Accounting Standards Issued But Not Yet Effective
A number of new standards, and amendments to standards and interpretations, are not yet effective for the six months ended April 30, 2026, and have not been early adopted in preparing these condensed interim consolidated financial statements. These new standards, and amendments to standards and interpretations are either not applicable or are not expected to have a significant impact on the Company’s condensed interim consolidated financial statements.
Change in Accounting Policies
There have been no changes in accounting policies during the six months ended April 30, 2026.
10
CLEARMIND MEDICINE INC.
Management’s Discussion and Analysis
For the Three and Six Months Ended April 30, 2026
Significant Accounting Estimates and Judgments
The preparation of condensed interim consolidated financial statements in accordance with IFRS requires management to make judgments, estimates, and assumptions that affect the application of policies and reported amounts of assets, liabilities, income, and expenses. The estimates and associated assumptions are based on historical experience and various other factors that are believed to be reasonable under the circumstances, the results of which form the basis of making the judgments about carrying values of assets and liabilities that are not readily apparent from other sources. Actual results may differ from these estimates.
Significant Estimates
Derivative Warrant Liabilities and Assets
The Company analyses warrants issued to determine whether they meet the classification as liabilities or equity. Derivative warrant liabilities and assets are adjusted to reflect their fair value at each reporting period, with any increase or decrease in the fair value recorded in the results of operations. The Company uses a fair valuation specialist to estimate the value of these instruments using the Black and Scholes and binomial pricing model.
The key assumptions used in the models are the expected future volatility in the price of the Company’s shares, the expected life of the warrants, the risk-free interest rate and the probability of any future adjustment event.
Significant Judgments
The critical judgments that the Company’s management has made in the process of applying the Company’s accounting policies that have the most significant effect on the amounts recognized in the Company’s consolidated financial statements are as follows:
Going Concern
The application of the going concern assumption which requires management to take into account all available information about the future, which is at least but not limited to 12 months from the year end of the reporting period. The Company is aware that material uncertainties related to events or conditions may cast significant doubt upon the Company’s ability to continue as a going concern.
Disclosure of Outstanding Share Data
Authorized share capital consists of an unlimited number of common shares without par value.
As of April 30, 2026, and June 15, 2026, the Company had 1,019,110 and 1,485,551 common shares issued and outstanding, respectively.
As of April 30, 2026, and June 15, 2026, the Company had 14 and 9 stock options outstanding, respectively.
As of April 30, 2026, and June 15, 2026, the Company had 370,038 and 541,471 warrants outstanding, respectively.
As of April 30, 2026, and June 15, 2026, the Company had 3 RSUs outstanding.
Risks and Uncertainties
The Company business, and investing in the Company’s securities, are subject to numerous risks, as more fully described in the section entitled “Risk Factors” and other risk factors contained in the Company’s Annual Information Form filed in SEDAR+ on January 20, 2026 and in the Company’s Annual Report on Form 20-F filed with the U.S. Securities and Exchange Commission on January 20, 2026. If any of these risks actually occur, the Company’s business, financial condition or results of operations would likely be materially adversely affected. In each case, the trading price of the Company’s securities would likely decline, and investors may lose all or part of their investment.
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