STOCK TITAN

Cocrystal Pharma (COCP) insider buys 10,000 shares via trust

(Neutral)
(Neutral)
Form Type
4

Rhea-AI Filing Summary

Phillip Frost M.D., a director and 10% owner of Cocrystal Pharma, Inc., reported an indirect open-market purchase of 10,000 shares of Common Stock on August 5, 2026 at a weighted average price of $0.9816, with individual trade prices ranging from $0.972 to $0.9898, through Frost Gamma Investments Trust. After this purchase, the trust holds 1,993,551 shares indirectly, while Frost also reports 27,100 shares held directly, including shares issuable upon vesting of restricted stock units. Frost disclaims beneficial ownership of the trust-held securities and of securities owned by OPKO Health, Inc., except to the extent of any pecuniary interest, and the transaction was not reported as pursuant to a Rule 10b5-1 trading plan.

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Insider FROST PHILLIP MD ET AL
Role Director, 10% Owner
Bought 10,000 shs ($10K)
Type Security Shares Price Value
Purchase Common Stock F1, F2 10,000 $0.9816 $10K
holding Common Stock F3 -- -- --
Holdings After Transaction: Common Stock — 1,993,551 shares (Indirect, By Frost Gamma Investments Trust); Common Stock — 27,100 shares (Direct)
Footnotes (3)
  1. F1. The price reported in Column 4 is a weighted average price. These securities were purchased in multiple transactions ranging from $0.972 to $0.9898, inclusive. The reporting person undertakes to provide to Cocrystal Pharma, Inc., any security holder of Cocrystal Pharma, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the shares purchased at each separate price within the ranges set forth in the preceding sentence.
  2. F2. These shares are held by Frost Gamma Investments Trust, of which Phillip Frost M.D., is the trustee. Frost Gamma L.P. is the sole and exclusive beneficiary of Frost Gamma Investments Trust. Dr. Frost is one of two limited partners of Frost Gamma L.P. The general partner of Frost Gamma L.P. is Frost Gamma, Inc., and the sole stockholder of Frost Gamma, Inc. is Frost-Nevada Corporation. Dr. Frost is the sole stockholder of Frost-Nevada Corporation. The Reporting Person disclaims beneficial ownership of the securities held by Frost Gamma Investments Trust except to the extent of any pecuniary interest therein, and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of these securities for purposes of Section 16 or for any other purpose.
  3. F3. Includes shares of common stock issuable upon vesting of restricted stock units.
Shares purchased 10,000 shares Indirect open-market purchase on August 5, 2026
Weighted average price $0.9816 per share Price for 10,000-share purchase on August 5, 2026
Trade price range $0.972 to $0.9898 per share Range of individual trades in the August 5, 2026 purchase
Indirect holdings after transaction 1,993,551 shares Common Stock held indirectly via Frost Gamma Investments Trust
Direct holdings after transaction 27,100 shares Directly held Common Stock, including shares issuable upon RSU vesting
weighted average price financial
"The price reported in Column 4 is a weighted average price."
Weighted average price is the average price of a security where each trade or component is counted according to its size, so bigger trades pull the average more than smaller ones. Think of it like calculating the average cost of a grocery haul where items you bought more of have greater influence on the final per-item cost. Investors use it to understand the true average price paid or received, judge execution quality, and compare trading performance against market movement.
restricted stock units financial
"Includes shares of common stock issuable upon vesting of restricted stock units."
Restricted stock units are a type of company reward where employees are promised shares of stock, but they only fully own these shares after meeting certain conditions, like staying with the company for a set time. They matter because they can become valuable assets and are often used to motivate employees to help the company succeed.
beneficial ownership regulatory
"The Reporting Person disclaims beneficial ownership of the securities held by Frost Gamma Investments Trust"
Beneficial ownership means the person or entity that actually enjoys the benefits of owning shares or other assets — such as receiving dividends, voting rights, or price gains — even if the legal title is held in another name. For investors it matters because knowing who truly controls and profits from a company reveals who can influence decisions, exposes potential conflicts of interest or hidden concentration of power, and affects transparency and risk in the stock.
pecuniary interest financial
"except to the extent of any pecuniary interest therein"
Section 16 regulatory
"for purposes of Section 16 or for any other purpose."
Section 16 is a U.S. securities law rule that governs the trading and disclosure obligations of company insiders — typically officers, directors and large shareholders — to promote transparency and deter unfair profit-taking. It requires insiders to publicly report their stock trades and allows companies or the issuer to reclaim quick, short-term profits from certain insider trades, like a scoreboard and a refund policy that help investors see and limit possible insider advantage.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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FAQ

What insider share purchase in COCP did Phillip Frost report on August 5, 2026?

Phillip Frost reported an indirect purchase of 10,000 shares of Cocrystal Pharma (COCP) Common Stock on August 5, 2026. The shares were bought through Frost Gamma Investments Trust at a weighted average price of $0.9816 per share in multiple open-market transactions.

At what prices were Phillip Frost’s August 5, 2026 COCP share purchases executed?

The August 5, 2026 COCP purchases had a weighted average price of $0.9816 per share. According to the disclosure, individual trades occurred in a price range from $0.972 to $0.9898 per share in multiple open-market transactions.

How many Cocrystal Pharma (COCP) shares does Phillip Frost report owning after this Form 4?

After the reported transaction, Frost Gamma Investments Trust holds 1,993,551 COCP shares indirectly linked to Phillip Frost. He also reports 27,100 shares held directly, which include shares of common stock issuable upon vesting of restricted stock units, per the disclosure.

Was Phillip Frost’s August 5, 2026 COCP trade made under a Rule 10b5-1 plan?

The August 5, 2026 COCP transaction was not reported as being made under a Rule 10b5-1 trading plan. The Rule 10b5-1 checkbox for this report is unchecked, and no footnote indicates that a pre-arranged trading plan governed the trades.

Does this COCP Form 4 include Cocrystal Pharma shares owned by OPKO Health, Inc.?

No. The report explicitly states it does not include any COCP securities owned directly by OPKO Health, Inc. Phillip Frost, OPKO’s Chairman and CEO, disclaims beneficial ownership of OPKO’s Cocrystal Pharma securities except for any pecuniary interest he may have in them.
SEC Form 4
FORM 4UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number:3235-0287
Estimated average burden
hours per response:0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
FROST PHILLIP MD ET AL

(Last)(First)(Middle)
4400 BISCAYNE BLVD

(Street)
MIAMI FLORIDA 33137-3227

(City)(State)(Zip)

UNITED STATES

(Country)
2. Issuer Name and Ticker or Trading Symbol
Cocrystal Pharma, Inc. [ COCP ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
XDirectorX10% Owner
Officer (give title below)Other (specify below)
2a. Foreign Trading Symbol
3. Date of Earliest Transaction (Month/Day/Year)
08/05/2026
6. Individual or Joint/Group Filing (Check Applicable Line)
XForm filed by One Reporting Person
Form filed by More than One Reporting Person
4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year)2A. Deemed Execution Date, if any (Month/Day/Year)3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeVAmount(A) or (D)Price
Common Stock08/05/2026P10,000A$0.9816(1)1,993,551IBy Frost Gamma Investments Trust(2)
Common Stock27,100(3)D
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year)3A. Deemed Execution Date, if any (Month/Day/Year)4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year)7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Explanation of Responses:
1. The price reported in Column 4 is a weighted average price. These securities were purchased in multiple transactions ranging from $0.972 to $0.9898, inclusive. The reporting person undertakes to provide to Cocrystal Pharma, Inc., any security holder of Cocrystal Pharma, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the shares purchased at each separate price within the ranges set forth in the preceding sentence.
2. These shares are held by Frost Gamma Investments Trust, of which Phillip Frost M.D., is the trustee. Frost Gamma L.P. is the sole and exclusive beneficiary of Frost Gamma Investments Trust. Dr. Frost is one of two limited partners of Frost Gamma L.P. The general partner of Frost Gamma L.P. is Frost Gamma, Inc., and the sole stockholder of Frost Gamma, Inc. is Frost-Nevada Corporation. Dr. Frost is the sole stockholder of Frost-Nevada Corporation. The Reporting Person disclaims beneficial ownership of the securities held by Frost Gamma Investments Trust except to the extent of any pecuniary interest therein, and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of these securities for purposes of Section 16 or for any other purpose.
3. Includes shares of common stock issuable upon vesting of restricted stock units.
Remarks:
This Form 4 does not include any of the securities owned directly by OPKO Health, Inc., a company of which Dr. Frost is the Chairman of the Board and Chief Executive Officer, concerning the securities of which Dr. Frost does not hold voting and investment control. Dr. Frost disclaims beneficial ownership of the securities held by OPKO Health, Inc. except to the extent of any pecuniary interest therein and this report shall not be deemed an admission that Dr. Frost is the beneficial owner of the securities for purposes of Section 16 or for any other purpose.
/s/ Phillip Frost, MD ET AL08/06/2026
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)