BlackRock (CTMX holder) discloses 7.6% beneficial stake in CytomX Therapeutics

Rhea-AI Filing Summary

BlackRock, Inc. reports a significant ownership position in CytomX Therapeutics, Inc. common stock on a passive Schedule 13G basis. BlackRock beneficially owns 16,551,452 shares, representing 7.6% of the outstanding common stock. It has sole voting power over 16,307,550 shares and sole dispositive power over all 16,551,452 shares, with no shared voting or dispositive power. Various underlying clients and accounts have rights to dividends or sale proceeds from these shares, but no single such person holds more than five percent of CytomX’s total outstanding common stock. The filing is signed on behalf of BlackRock by a managing director.

Key Figures

Beneficial ownership: 16,551,452 shares Ownership percentage: 7.6% Sole voting power: 16,307,550 shares +3 more

6 metrics

Beneficial ownership 16,551,452 shares CytomX common stock beneficially owned by BlackRock

Ownership percentage 7.6% Percent of CytomX common stock class beneficially owned by BlackRock

Sole voting power 16,307,550 shares Shares of CytomX over which BlackRock has sole power to vote

Shared voting power 0 Shares of CytomX over which BlackRock has shared power to vote

Sole dispositive power 16,551,452 shares Shares over which BlackRock has sole power to dispose or direct disposition

Shared dispositive power 0 Shares over which BlackRock has shared power to dispose

Key Terms

beneficially owned, Sole Voting Power, Sole Dispositive Power, Schedule 13G, +1 more

5 terms

beneficially owned financial

"this reflects the securities beneficially owned, or deemed to be beneficially owned"

Beneficially owned describes securities or assets where a person has the economic rights and control—such as the right to receive dividends and to direct voting—even if legal title is held in another name. Think of it like having the keys and using a car that’s registered to someone else: you get the benefits and make decisions. Investors care because beneficial ownership reveals who truly controls value and voting power, affecting corporate decisions and takeover dynamics.

Sole Voting Power financial

"5 | Sole Voting Power 16,307,550.00 6 | Shared Voting Power 0.00"

Sole voting power is the exclusive right to cast votes attached to a shareholder’s stock without needing approval from anyone else. Like holding the only remote control for a TV, it lets that holder decide corporate matters such as board members, mergers, and policy changes, making it important to investors because it concentrates control and can strongly influence a company’s strategy and the value of its shares.

Sole Dispositive Power financial

"7 | Sole Dispositive Power 16,551,452.00 8 | Shared Dispositive Power 0.00"

Sole dispositive power is the exclusive legal authority to decide what happens to a security — for example, whether to sell, transfer, or retain shares — without needing anyone else’s permission. Investors care because it signals who truly controls the economic outcome of an investment: like holding the only key to a safe, the holder can realize gains or losses and may trigger regulatory reporting, insider rules, or influence over corporate ownership.

Schedule 13G regulatory

"this schedule has been filed on a Schedule 13G basis for ownership"

A Schedule 13G is a formal document that investors file with the government when they acquire a large ownership stake in a company, usually for investment purposes rather than control. It helps keep the public informed about who owns significant parts of a company's shares, which can influence how the company is managed and how investors make decisions. Filing this schedule is important for transparency and understanding the ownership landscape of publicly traded companies.

Power of Attorney regulatory

"Exhibit 24: Power of Attorney Exhibit 99: Item 7"

A power of attorney is a legal document that allows one person to make decisions and act on behalf of another person, often in financial or legal matters. It’s like giving someone a trusted helper or agent the authority to handle important tasks if you are unable to do so yourself. This matters to investors because it can impact how their assets are managed or transferred if they become unable to oversee their affairs.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Available on EDGAR 07/27/2026 - 04:26 PM Accepted by SEC EDGAR 07/27/2026 - 04:25 PM Learn about SEC filing dates

FAQ

What percentage of CYTOMX THERAPEUTICS, INC (CTMX) does BlackRock currently own?

BlackRock beneficially owns 7.6% of CytomX Therapeutics’ common stock, representing 16,551,452 shares. This ownership gives BlackRock a notable institutional stake but does not indicate any change in control or an activist position in the company.

How many CYTOMX THERAPEUTICS, INC (CTMX) shares does BlackRock report as beneficially owned?

BlackRock reports beneficial ownership of 16,551,452 CytomX common shares. This position is disclosed on a Schedule 13G, which is typically used for passive ownership stakes rather than activist or control-oriented positions in a public company.

What voting power does BlackRock have over CYTOMX THERAPEUTICS, INC (CTMX) shares?

BlackRock has sole voting power over 16,307,550 CytomX shares and no shared voting power. It also has sole dispositive power over the full 16,551,452 shares, meaning it can decide how those shares are voted and disposed of, subject to client arrangements.

Is any single BlackRock client a more-than-5% holder of CYTOMX THERAPEUTICS, INC (CTMX)?

No single underlying person related to BlackRock’s holdings has more than 5% of CytomX’s outstanding common stock. Various persons have rights to dividends or sale proceeds, but each individual interest remains below the 5% ownership threshold.

What type of SEC filing did BlackRock submit regarding CYTOMX THERAPEUTICS, INC (CTMX)?

BlackRock submitted a Schedule 13G for CytomX Therapeutics common stock. Schedule 13G is used by certain investors to report beneficial ownership positions of over 5% when they do not seek to change or influence control of the issuer.

Who signed the CYTOMX THERAPEUTICS, INC (CTMX) Schedule 13G on behalf of BlackRock?

The Schedule 13G regarding CytomX Therapeutics was signed by Spencer Fleming, a Managing Director at BlackRock. The filing references a Power of Attorney (Exhibit 24) authorizing execution of the report on behalf of BlackRock.

SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13G

UNDER THE SECURITIES EXCHANGE ACT OF 1934

CYTOMX THERAPEUTICS, INC

(Name of Issuer)

Common Stock

(Title of Class of Securities)

23284F105

(CUSIP Number)

06/30/2026

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

Rule 13d-1(b)

Rule 13d-1(c)

Rule 13d-1(d)

schemaVersion:

SCHEDULE 13G

CUSIP Number(s): 23284F105

1

Names of Reporting Persons

BlackRock, Inc.

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 16,307,550.00
6	Shared Voting Power 0.00
7	Sole Dispositive Power 16,551,452.00
8	Shared Dispositive Power 0.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

16,551,452.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

7.6 %

12

Type of Reporting Person (See Instructions)

HC

SCHEDULE 13G

Item 1.
(a)	Name of issuer: CYTOMX THERAPEUTICS, INC
(b)	Address of issuer's principal executive offices: 151 OYSTER POINT BLVD.SUITE 400 SOUTH SAN FRANCISCO CA 94080
Item 2.
(a)	Name of person filing: BlackRock, Inc. In accordance with SEC Release No. 34-39538 (January 12, 1998), this Schedule 13G reflects the securities beneficially owned, or deemed to be beneficially owned, by certain business units (collectively, the "Reporting Business Units") of BlackRock, Inc. and its subsidiaries and affiliates. It does not include securities, if any, beneficially owned by other business units whose beneficial ownership of securities are disaggregated from that of the Reporting Business Units in accordance with such release.
(b)	Address or principal business office or, if none, residence: BlackRock, Inc., 50 Hudson Yards New York, NY 10001
(c)	Citizenship: See Item 4 of Cover Page
(d)	Title of class of securities: Common Stock
(e)	CUSIP Number(s): 23284F105
Item 3.	If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)	Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)	Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)	Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)	Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)	An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)	An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)	A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)	A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)	A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)	A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J), please specify the type of institution:
(k)	Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.	Ownership
(a)	Amount beneficially owned: 16551452
(b)	Percent of class: 7.6 %
(c)	Number of shares as to which the person has:
	(i) Sole power to vote or to direct the vote: 16307550
	(ii) Shared power to vote or to direct the vote: 0
	(iii) Sole power to dispose or to direct the disposition of: 16551452
	(iv) Shared power to dispose or to direct the disposition of: 0
Item 5.	Ownership of 5 Percent or Less of a Class.
	Not Applicable
Item 6.	Ownership of more than 5 Percent on Behalf of Another Person.
	If any other person is known to have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, such securities, a statement to that effect should be included in response to this item and, if such interest relates to more than 5 percent of the class, such person should be identified. A listing of the shareholders of an investment company registered under the Investment Company Act of 1940 or the beneficiaries of employee benefit plan, pension fund or endowment fund is not required. Various persons have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of the common stock of CYTOMX THERAPEUTICS, INC. No one person's interest in the common stock of CYTOMX THERAPEUTICS, INC is more than five percent of the total outstanding common shares.
Item 7.	Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
	If a parent holding company has filed this schedule, pursuant to Rule 13d-1(b)(ii)(G), so indicate under Item 3(g) and attach an exhibit stating the identity and the Item 3 classification of the relevant subsidiary. If a parent holding company has filed this schedule pursuant to Rule 13d-1(c) or Rule 13d-1(d), attach an exhibit stating the identification of the relevant subsidiary. See Exhibit 99
Item 8.	Identification and Classification of Members of the Group.
	Not Applicable
Item 9.	Notice of Dissolution of Group.
	Not Applicable

Item 10.

Certifications:

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

BlackRock, Inc.

Signature:	Spencer Fleming
Name/Title:	Managing Director
Date:	07/27/2026

Exhibit Information

Exhibit 24: Power of Attorney Exhibit 99: Item 7