Perceptive reports 563,239 shares (6.7%) in EDESA

EDESA BIOTECH, INC. reports that Perceptive Life Sciences Master Fund, Ltd. directly holds 563,239 Common Shares, equal to 6.7% of the class based on 8,348,161 outstanding Common Shares as of February 12, 2026.

Rhea-AI Filing Summary

EDESA BIOTECH, INC. reports that Perceptive Life Sciences Master Fund, Ltd. directly holds 563,239 Common Shares, equal to 6.7% of the class based on 8,348,161 outstanding Common Shares as of February 12, 2026.

The Schedule 13G lists the Reporting Persons as Perceptive Advisors LLC, Joseph Edelman and the Master Fund; each is reported with shared voting and shared dispositive power over the 563,239 shares.

Insights

Institutional Ownership Analyst

Large passive stake disclosed: 563,239 shares (6.7%).

The filing shows the Master Fund directly holds 563,239 Common Shares, representing 6.7% of the class using the issuer's outstanding share count as of February 12, 2026. Perceptive Advisors and Joseph Edelman are reported as having shared voting and dispositive power.

Because this is a Schedule 13G, the position is presented as passive. Future Schedule 13D/13G amendments would disclose any change in intent or material activity in the stake.

Securities Compliance Counsel

Disclosure aligns with beneficial ownership rules for passive investors.

The report identifies the three Reporting Persons and ties the percentage calculation to February 12, 2026 outstanding shares (8,348,161). It specifies shared voting and shared dispositive power of 563,239 shares, consistent with aggregated attribution among related reporting entities.

Material change in ownership or intent would require an amended filing; the filing includes a Joint Filing Agreement as Exhibit 99.1.

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

What stake does Perceptive (EDSA) report owning?

Perceptive reports beneficial ownership of 563,239 shares, or 6.7%. The percentage uses an outstanding share base of 8,348,161 as of February 12, 2026, and the shares are listed under shared voting and dispositive power.

Who are the reporting persons in the Schedule 13G for EDSA?

The filing names Perceptive Advisors LLC, Joseph Edelman, and the Master Fund. The address for the Reporting Persons is 51 Astor Place, New York, and a Joint Filing Agreement is attached as Exhibit 99.1.

Does the Schedule 13G state whether the stake is passive or active?

The Schedule 13G format indicates a passive reporting posture. The filing does not assert active control; any change in intent would typically trigger an amended Schedule 13D or 13G per disclosure rules.

How is voting and disposition power reported for these shares?

The filing reports 0 sole power and 563,239 shared voting and shared dispositive power. Each Reporting Person is shown as having shared voting and shared dispositive authority over the same 563,239 shares.

What outstanding share figure did the filing use to calculate the percentage?

The filing uses 8,348,161 outstanding Common Shares to compute the percentage. That outstanding share count is cited from the issuer's Form 10-Q filed on February 13, 2026 referencing shares outstanding as of February 12, 2026.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Accepted by SEC EDGAR 03/16/2026 - 04:00 PM Learn about SEC filing dates

SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13G

UNDER THE SECURITIES EXCHANGE ACT OF 1934

EDESA BIOTECH, INC.

(Name of Issuer)

Common Shares, without par value

(Title of Class of Securities)

(CUSIP Number)

03/09/2026

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

Rule 13d-1(b)

Rule 13d-1(c)

Rule 13d-1(d)

schemaVersion:

SCHEDULE 13G

CUSIP No.

1

Names of Reporting Persons

Perceptive Advisors LLC

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 563,239.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 563,239.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

563,239.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

6.7 %

12

Type of Reporting Person (See Instructions)

IA

SCHEDULE 13G

CUSIP No.

1

Names of Reporting Persons

Joseph Edelman

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

UNITED STATES

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 563,239.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 563,239.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

563,239.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

6.7 %

12

Type of Reporting Person (See Instructions)

IN

SCHEDULE 13G

CUSIP No.

1

Names of Reporting Persons

Perceptive Life Sciences Master Fund, Ltd.

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

CAYMAN ISLANDS

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 563,239.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 563,239.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

563,239.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

6.7 %

12

Type of Reporting Person (See Instructions)

CO

SCHEDULE 13G

Item 1.
(a)	Name of issuer: EDESA BIOTECH, INC.
(b)	Address of issuer's principal executive offices: 100 Spy Court, Markham, ON, Canada L3R 5H6
Item 2.
(a)	Name of person filing: The names of the persons filing this report (collectively, the "Reporting Persons") with respect to the Common Shares, without par value (the "Common Shares") of EDESA BIOTECH, INC. (the "Issuer") are: (i) Perceptive Advisors LLC ("Perceptive Advisors") (ii) Joseph Edelman ("Mr. Edelman") (iii) Perceptive Life Sciences Master Fund, Ltd. (the "Master Fund")
(b)	Address or principal business office or, if none, residence: The address of the principal business office of each of the Reporting Persons is: 51 Astor Place, 10th Floor, New York, NY 10003
(c)	Citizenship: Perceptive Advisors is a Delaware limited liability company. Mr. Edelman is a United States citizen. The Master Fund is a Cayman Islands corporation.
(d)	Title of class of securities: Common Shares, without par value
(e)	CUSIP No.:
Item 3.	If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)	Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)	Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)	Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)	Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)	An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)	An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)	A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)	A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)	A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)	A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J), please specify the type of institution:
(k)	Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.	Ownership
(a)	Amount beneficially owned: The information required by this item with respect to each Reporting Person is set forth in Rows 5 through 9 and 11 of the cover pages to this Schedule 13G. The ownership percentages are based on 8,348,161 outstanding Common Shares as of February 12, 2026, as reported in the Issuer's Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on February 13, 2026. The Master Fund directly holds 563,239 Common Shares. Perceptive Advisors serves as the investment manager to the Master Fund and may be deemed to beneficially own shares held by the Master Fund. Mr. Edelman is the managing member of Perceptive Advisors and may be deemed to beneficially own the shares held by the Master Fund.
(b)	Percent of class: Perceptive Advisors: 6.7% Mr. Edelman: 6.7% Master Fund: 6.7%
(c)	Number of shares as to which the person has:
	(i) Sole power to vote or to direct the vote: Perceptive Advisors: 0 Mr. Edelman: 0 Master Fund: 0
	(ii) Shared power to vote or to direct the vote: Perceptive Advisors: 563,239 Mr. Edelman: 563,239 Master Fund: 563,239
	(iii) Sole power to dispose or to direct the disposition of: Perceptive Advisors: 0 Mr. Edelman: 0 Master Fund: 0
	(iv) Shared power to dispose or to direct the disposition of: Perceptive Advisors: 563,239 Mr. Edelman: 563,239 Master Fund: 563,239
Item 5.	Ownership of 5 Percent or Less of a Class.
	Not Applicable
Item 6.	Ownership of more than 5 Percent on Behalf of Another Person.
	Not Applicable
Item 7.	Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
	Not Applicable
Item 8.	Identification and Classification of Members of the Group.
	Not Applicable
Item 9.	Notice of Dissolution of Group.
	Not Applicable

Item 10.

Certifications:

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

Perceptive Advisors LLC

Signature:	/s/ Joseph Edelman
Name/Title:	Joseph Edelman, Managing Member
Date:	03/16/2026

Joseph Edelman

Signature:	/s/ Joseph Edelman
Name/Title:	Joseph Edelman
Date:	03/16/2026

Perceptive Life Sciences Master Fund, Ltd.

Signature:	/s/ Joseph Edelman
Name/Title:	Joseph Edelman, Managing Member
Date:	03/16/2026

Exhibit Information

Exhibit 99.1 - Joint Filing Agreement