Welcome to our dedicated page for ENANTA PHARMACEUTICALS SEC filings (Ticker: ENTA), a comprehensive resource for investors and traders seeking official regulatory documents including 10-K annual reports, 10-Q quarterly earnings, 8-K material events, and insider trading forms.
Enanta Pharmaceuticals, Inc. filings document a clinical-stage biotechnology issuer focused on small-molecule therapies for viral infections and immunological diseases. Its Form 8-K disclosures cover financial results, Regulation FD clinical-data materials, research and development updates, material agreements and capital-structure information for common stock traded under ENTA on the Nasdaq Global Select Market.
Proxy and annual meeting filings record governance matters including director elections, advisory executive compensation votes, auditor ratification and amendments to the 2019 Equity Incentive Plan. Other event disclosures also document patent litigation matters, including proceedings involving U.S. Patent No. 11,358,953 and Pfizer's COVID-19 antiviral Paxlovid.
Enanta Pharmaceuticals entered an Open Market Sale Agreement with Jefferies LLC that allows it to sell up to $75,000,000 of common stock from time to time through an at-the-market program. Shares will be issued under Enanta’s effective Form S-3 shelf registration and a July 2, 2026 prospectus supplement.
Jefferies will act as sales agent and use commercially reasonable efforts to place shares on Nasdaq or other markets, earning a commission of up to 3.0% of the gross sales price per share. Enanta is not obligated to sell any shares, and the arrangement can be terminated in accordance with the agreement’s terms.
Enanta Pharmaceuticals intends to offer and sell up to $75,000,000 of its common stock through an Open Market Sale (sales agreement) with Jefferies LLC as sales agent under an at-the-market offering structure. The sales agreement permits sales from time to time through Jefferies, which may receive commissions up to 3.0% of aggregate gross proceeds. The prospectus supplement uses an assumed offering price of $14.77 per share (the last reported sale price on July 1, 2026) to illustrate an aggregate issuance of 5,077,860 shares and presents illustrative dilution and as-adjusted net tangible book value. Shares outstanding are shown as 29,061,152 as of March 31, 2026. Sales may occur at varying prices and quantities; Jefferies is not required to sell any specific amount and will act using commercially reasonable efforts on mutually agreed terms.
Enanta Pharmaceuticals, Inc. reported that the United States Court of Appeals for the Federal Circuit has affirmed a prior summary judgment ruling in its patent case against Pfizer Inc. The Federal Circuit ruled that the claims of Enanta’s U.S. Patent No. 11,358,953, related to Pfizer’s COVID-19 antiviral Paxlovid, are invalid, effectively upholding the December 2024 decision from the U.S. District Court for the District of Massachusetts.
Enanta Pharmaceuticals is advancing its RSV antiviral zelicapavir into a single registrational Phase 2b/3 trial in high-risk adult outpatients after a successful End-of-Phase 2 FDA meeting. The Phase 2b portion will enroll at least 200 patients, with approximately 660 more in Phase 3, and topline Phase 2b data expected in 2027.
The company also plans a Phase 2b pediatric trial in children 28 days to 36 months old, starting in the third quarter of 2026, with topline data also expected in 2027. Earlier Phase 2 data showed clinically meaningful improvements, including a 6.7-day faster symptom resolution and lower RSV-related hospitalizations in high-risk adults, and antiviral and symptom benefits in children.
Zelicapavir, an RSV N-protein inhibitor with FDA Fast Track designation, has been well tolerated in more than 700 subjects. Enanta estimates an oral RSV antiviral for children and high-risk adults represents a global opportunity of over $2 billion, with a potential U.S. addressable population greater than 3 million patients.
Enanta Pharmaceuticals reported royalty-based revenue of $17.2 million for the three months ended March 31, 2026, up from $14.9 million a year earlier, driven by higher MAVYRET/MAVIRET sales at AbbVie. Net loss narrowed to $13.1 million from $22.6 million as research and development spending fell to $19.4 million and general and administrative costs declined to $9.6 million.
For the six-month period, revenue reached $35.8 million and net loss was $25.0 million. The company ended the quarter with $227.0 million in cash, cash equivalents and marketable securities and expects this, plus its retained share of HCV royalties, to fund operations into fiscal 2029. Enanta continues to advance wholly owned RSV and immunology programs, including Phase 2 RSV candidate zelicapavir and a new Phase 1 KIT inhibitor, while carrying a royalty sale liability of $128.8 million related to its OMERS transaction.
Enanta Pharmaceuticals Inc — The Vanguard Group filed an amended Schedule 13G reporting 0 shares beneficially owned of Common Stock, representing 0%, following an internal realignment.
The amendment states that on January 12, 2026 The Vanguard Group, Inc. reorganized and certain subsidiaries or business divisions will report beneficial ownership separately in reliance on SEC Release No. 34-39538. The filing is signed by Ashley Grim, Head of Global Fund Administration, dated 03/26/2026.
Enanta Pharmaceuticals director Terry Vance received a grant of stock options covering 20,000 shares of common stock. The options have an exercise price of 14.1700 per share and expire on March 11, 2036. Following this grant, Vance holds 20,000 options.
The option award vests monthly in substantially equal installments over one year starting on March 11, 2026, with the final monthly installment vesting no later than the nearest Nasdaq Global Select Market trading day before Enanta’s 2027 annual stockholders’ meeting. This is a compensation-related grant, not an open-market share purchase.
Enanta Pharmaceuticals director Lesley Russell received a stock option grant for 20,000 shares of Common Stock. The option has an exercise price of $14.17 per share and expires on March 11, 2036. It vests in substantially equal monthly installments over one year starting on March 11, 2026, with the final installment vesting before the 2027 annual meeting of stockholders.