Erasca, Inc. Schedule 13G: RTW Investments, LP and Roderick Wong report shared beneficial ownership of 16,157,175 shares of Erasca common stock, representing 5.2% of the class based on 310,799,547 shares outstanding as of March 5, 2026. The filing shows shared voting and dispositive power over these shares held by the RTW Funds. The statement is signed by Dr. Wong on May 15, 2026.
Positive
None.
Negative
None.
Insights
Large passive stake reported: RTW Funds and Dr. Wong hold 16.16M shares (5.2%).
The filing lists 16,157,175 shares as beneficially owned with shared voting and dispositive power, calculated from 310,799,547 shares outstanding as of March 5, 2026. This reflects a disclosed, non-control institutional stake held through the RTW Funds.
Cash‑flow treatment and plans for disposition are not stated in the excerpt; subsequent filings would disclose any sales or changes in ownership.
Key Figures
Shares beneficially owned:16,157,175 sharesPercent of class:5.2%Shares outstanding:310,799,547 shares
3 metrics
Shares beneficially owned16,157,175 sharesReported by RTW Investments / Roderick Wong
Percent of class5.2%Calculated using shares outstanding as of <date>March 5, 2026</date>
Shares outstanding310,799,547 sharesAs of <date>March 5, 2026</date> per Form 10-K
"The information required by Item 4(a) is set forth in Rows 5 - 9"
Beneficially owned describes securities or assets where a person has the economic rights and control—such as the right to receive dividends and to direct voting—even if legal title is held in another name. Think of it like having the keys and using a car that’s registered to someone else: you get the benefits and make decisions. Investors care because beneficial ownership reveals who truly controls value and voting power, affecting corporate decisions and takeover dynamics.
shared voting powercorporate governance
"Shared Voting Power 16,157,175.00"
Shared voting power occurs when two or more parties jointly have the right to vote or decide how a block of company shares is cast, like co-owners who must agree before moving a piece of furniture. Investors care because who controls voting rights affects board elections, major corporate decisions and takeover outcomes, and shared control can alter regulatory disclosures and the practical influence any holder has over a company’s direction and value.
Schedule 13Gregulatory
"This statement is filed by: RTW Investments, LP"
A Schedule 13G is a formal document that investors file with the government when they acquire a large ownership stake in a company, usually for investment purposes rather than control. It helps keep the public informed about who owns significant parts of a company's shares, which can influence how the company is managed and how investors make decisions. Filing this schedule is important for transparency and understanding the ownership landscape of publicly traded companies.
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
SCHEDULE 13G
UNDER THE SECURITIES EXCHANGE ACT OF 1934
Erasca, Inc.
(Name of Issuer)
Common Stock, $0.0001 par value
(Title of Class of Securities)
29479A108
(CUSIP Number)
03/31/2026
(Date of Event Which Requires Filing of this Statement)
Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
Rule 13d-1(b)
Rule 13d-1(c)
Rule 13d-1(d)
schemaVersion:
SCHEDULE 13G
CUSIP Number(s):
29479A108
1
Names of Reporting Persons
RTW Investments, LP
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
DELAWARE
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
16,157,175.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
16,157,175.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
16,157,175.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
5.2 %
12
Type of Reporting Person (See Instructions)
IA, PN
SCHEDULE 13G
CUSIP Number(s):
29479A108
1
Names of Reporting Persons
Roderick Wong
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
UNITED STATES
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
16,157,175.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
16,157,175.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
16,157,175.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
5.2 %
12
Type of Reporting Person (See Instructions)
HC, IN
SCHEDULE 13G
Item 1.
(a)
Name of issuer:
Erasca, Inc.
(b)
Address of issuer's principal executive offices:
3115 Merryfield Row, Suite 300, San Diego, CA, 92121.
Item 2.
(a)
Name of person filing:
This statement is filed by:
(i) RTW Investments, LP ("RTW Investments"), a Delaware limited partnership and the investment adviser to certain funds (the "RTW Funds"), with respect to shares of Common Stock, par value $0.0001 per share (the "Shares") of Erasca, Inc. (the "Company") directly held by the RTW Funds; and
(ii) Roderick Wong, M.D. ("Dr. Wong"), the Managing Partner and Chief Investment Officer of RTW Investments, with respect to the Shares directly held by the RTW Funds.
The foregoing persons are hereinafter sometimes collectively referred to as the "Reporting Persons."
The filing of this statement should not be construed as an admission that any of the foregoing persons or any Reporting Person is, for the purposes of Section 13 of the Securities Exchange Act of 1934, as amended, the beneficial owner of the Shares reported herein.
(b)
Address or principal business office or, if none, residence:
The address of the business office of each of the Reporting Persons is 40 10th Avenue, Floor 7, New York, New York 10014.
(c)
Citizenship:
RTW Investments is a Delaware limited partnership. Dr. Wong is a citizen of the United States.
(d)
Title of class of securities:
Common Stock, $0.0001 par value
(e)
CUSIP Number(s):
29479A108
Item 3.
If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)
Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)
Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)
Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)
Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)
An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)
An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)
A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)
A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)
A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)
A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J),
please specify the type of institution:
(k)
Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.
Ownership
(a)
Amount beneficially owned:
The information required by Item 4(a) is set forth in Rows 5 - 9 of the cover page for each of the Reporting Persons and is incorporated herein by reference. The percentages set forth in Row 11 of the cover pages are calculated based upon 310,799,547 Shares outstanding as of March 5, 2026 as reported in the Company's Annual Report on Form 10-K filed with the Securities and Exchange Commission on March 12, 2026.
(b)
Percent of class:
RTW Investments: 5.2%
Dr. Wong: 5.2%
(c)
Number of shares as to which the person has:
(i) Sole power to vote or to direct the vote:
RTW Investments: 0
Dr. Wong: 0
(ii) Shared power to vote or to direct the vote:
RTW Investments: 16,157,175 Shares
Dr. Wong: 16,157,175 Shares
(iii) Sole power to dispose or to direct the disposition of:
RTW Investments: 0
Dr. Wong: 0
(iv) Shared power to dispose or to direct the disposition of:
RTW Investments: 16,157,175 Shares
Dr. Wong: 16,157,175 Shares
Item 5.
Ownership of 5 Percent or Less of a Class.
Not Applicable
Item 6.
Ownership of more than 5 Percent on Behalf of Another Person.
If any other person is known to have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, such securities, a statement to that effect should be included in response to this item and, if such interest relates to more than 5 percent of the class, such person should be identified. A listing of the shareholders of an investment company registered under the Investment Company Act of 1940 or the beneficiaries of employee benefit plan, pension fund or endowment fund is not required.
See Item 2. The RTW Funds have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, the Shares reported herein.
Item 7.
Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
Not Applicable
Item 8.
Identification and Classification of Members of the Group.
Not Applicable
Item 9.
Notice of Dissolution of Group.
Not Applicable
Item 10.
Certifications:
By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.
SIGNATURE
After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.
What stake does RTW Investments report in Erasca (ERAS)?
RTW Investments reports beneficial ownership of 16,157,175 shares, equal to 5.2% of Erasca common stock based on 310,799,547 shares outstanding as of March 5, 2026.
Does Roderick Wong personally control the ERAS shares reported?
The statement shows Dr. Wong has shared voting and dispositive power over 16,157,175 shares through RTW; it does not assert sole voting or sole dispositive power.
When was the ownership percentage for ERAS calculated?
The 5.2% figure is calculated using 310,799,547 shares outstanding as of March 5, 2026, as reported in the company’s Annual Report on Form 10-K filed March 12, 2026.
Who filed the Schedule 13G for ERAS and when was it signed?
The Schedule 13G was filed by RTW Investments, LP and Roderick Wong, M.D. and is signed by Dr. Wong with a signature date of May 15, 2026.
Are the RTW-held ERAS shares held directly by RTW or on behalf of funds?
The filing states the shares are directly held by the RTW Funds, for which RTW Investments acts as investment adviser and which have the right to receive dividends or sale proceeds.
