EXACT Sciences EVP granted 38,707 RSUs

ORVILLE JACOB A reported acquisition or exercise transactions in this Form 4 filing.

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Rhea-AI Filing Summary

ORVILLE JACOB A reported acquisition or exercise transactions in this Form 4 filing.

EXACT SCIENCES CORP EVP Jacob A. Orville received an equity award of 38,707 restricted stock units on February 25, 2026. Each restricted stock unit represents a contingent right to receive one share of common stock and vests in four equal annual installments beginning on February 25, 2027.

After this grant, Mr. Orville directly holds 100,403 shares of common stock and indirectly holds 1,759 shares through a 401(k) plan, for a total of 102,162 shares reported. He also holds, in the aggregate, an additional 45,288 vested and unvested options and restricted stock units.

Insider Trade Summary

Grant/Award: 38,707 shares

Grant/Award 3 txns

Insider ORVILLE JACOB A

Role EVP, GM, Screening

Type	Security	Shares	Price	Value
Grant/Award	Restricted Stock Units	38,707	$0.00	$0.00
holding	Common Stock	--	--	--
holding	Common Stock	--	--	--

Holdings After Transaction: Restricted Stock Units — 38,707 contracts (Direct); Common Stock — 100,403 shares (Direct); Common Stock — 1,759 shares (Indirect, Held in 401(k) Plan)

Footnotes (3)

F1. In addition to the shares of Common Stock reported on this Form 4, which total 102,162 shares, Mr. Orville also holds, in the aggregate, an additional 45,288 vested and unvested options to purchase shares of Common Stock and restricted stock units, with each restricted stock unit representing a contingent right to receive one share of Common Stock.
F2. Each restricted stock unit represents a contingent right to receive one share of common stock.
F3. These restricted stock units vest in four equal annual installments beginning on February 25, 2027.

FAQ

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What did EXACT SCIENCES (EXAS) EVP Jacob Orville report on this Form 4?

Jacob A. Orville reported receiving an award of 38,707 restricted stock units on February 25, 2026. These units represent a contingent right to receive common shares, adding to his existing stock, option, and restricted stock unit holdings in EXACT SCIENCES CORP.

How many restricted stock units did EXAS grant to Jacob Orville?

EXACT SCIENCES granted Jacob Orville 38,707 restricted stock units at a stated price of $0 per unit. Each unit represents a potential future share of common stock, subject to vesting conditions over time according to the award’s schedule.

What is the vesting schedule for Jacob Orville’s new EXAS restricted stock units?

The 38,707 restricted stock units vest in four equal annual installments beginning on February 25, 2027. This means portions of the award become deliverable each year, aligning long‑term compensation with ongoing service and company performance over multiple years.

How many EXAS common shares does Jacob Orville hold after this Form 4?

After the reported transactions, Jacob Orville holds 100,403 EXAS common shares directly and 1,759 shares indirectly through a 401(k) plan. Together, the Form 4 notes these holdings total 102,162 shares of EXACT SCIENCES CORP common stock.

Does Jacob Orville hold other EXAS equity awards besides the new RSUs?

Yes. In addition to the 102,162 EXAS shares reported, he also holds an aggregate 45,288 vested and unvested options and restricted stock units. Each restricted stock unit represents a contingent right to receive one share of EXACT SCIENCES common stock in the future.

Was there any open market buying or selling of EXAS shares in this Form 4?

No open market purchases or sales are shown in this Form 4. The main reported event is a grant of 38,707 restricted stock units, a form of equity compensation, rather than a market transaction involving buying or selling existing EXAS shares.

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Accepted by SEC EDGAR 02/27/2026 - 04:30 PM

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

ORVILLE JACOB A

(Last)

(First)

(Middle)

C/O EXACT SCIENCES CORP.

5505 ENDEAVOR LANE

(Street)

MADISON

53719

(City)

(State)

(Zip)

2. Issuer Name and Ticker or Trading Symbol
EXACT SCIENCES CORP [ EXAS ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director	10% Owner
X	Officer (give title below)	Other (specify below)
	EVP, GM, Screening

3. Date of Earliest Transaction (Month/Day/Year)
02/25/2026

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	Code	V	Amount	(A) or (D)	Price		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
Common Stock								100,403⁽¹⁾	D
Common Stock								1,759	I	Held in 401(k) Plan

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares	8. Price of Derivative Security (Instr. 5)		10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
Restricted Stock Units	⁽²⁾	02/25/2026		A		38,707		⁽³⁾	⁽³⁾	Common Stock	38,707	$0	38,707	D

Explanation of Responses:

1. In addition to the shares of Common Stock reported on this Form 4, which total 102,162 shares, Mr. Orville also holds, in the aggregate, an additional 45,288 vested and unvested options to purchase shares of Common Stock and restricted stock units, with each restricted stock unit representing a contingent right to receive one share of Common Stock.

2. Each restricted stock unit represents a contingent right to receive one share of common stock.

3. These restricted stock units vest in four equal annual installments beginning on February 25, 2027.

	/s/ Jacob A. Orville by Mark Busch, attorney-in-fact	02/27/2026
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

Source: View Original Filing on SEC EDGAR