STOCK TITAN

Fortress Biotech (NASDAQ: FBIO) turns 2025 profit with $205M PRV sale and new royalties

Filing Impact
(Very High)
Filing Sentiment
(Neutral)
Form Type
8-K

Rhea-AI Filing Summary

Fortress Biotech reported 2025 results showing a sharp improvement in profitability driven by asset monetizations and partner activity. Net revenue was $63.3 million for the year ended December 31, 2025, up from $57.7 million in 2024, mainly from product and other revenue.

Net income attributable to Fortress was $6.8 million, compared with a loss of $46.0 million in 2024, helped by a $27.1 million gain from deconsolidation of a subsidiary and $17.6 million of other income. Net loss attributable to common stockholders narrowed to $1.9 million, or $(0.07) per share.

Operationally, the FDA approved ZYCUBO for Menkes disease, and subsidiary Cyprium sold a Rare Pediatric Disease Priority Review Voucher for $205 million, with potential tiered royalties and up to approximately $128 million in sales milestones. The Checkpoint Therapeutics acquisition by Sun Pharma created eligibility for up to an additional $4.8 million under a contingent value right plus a 2.5% royalty on UNLOXCYT sales. Fortress also holds a 3% royalty on dotinurad sales through Crystalys Therapeutics.

Positive

  • Return to profitability: Net income attributable to Fortress was $6.8 million in 2025, a major improvement from a $46.0 million loss in 2024, while net loss attributable to common stockholders narrowed to $1.9 million, or $(0.07) per share.
  • Large non-dilutive cash inflow: Cyprium sold a Rare Pediatric Disease Priority Review Voucher for gross proceeds of $205 million and remains eligible for tiered royalties and up to approximately $128 million in aggregate sales milestones from Sentynl.
  • Growing royalty and milestone portfolio: Fortress is eligible for up to an additional $4.8 million under a contingent value right and a 2.5% royalty on UNLOXCYT net sales, plus a 3% royalty on dotinurad sales via Crystalys.

Negative

  • None.

Insights

Fortress turned 2025 into a profitable, deal-driven year with new royalties and milestones.

Fortress Biotech shifted from a large 2024 loss to $6.8M of net income attributable to Fortress in 2025. This was supported by modestly higher net revenue of $63.3M and a major $27.1M gain from deconsolidating a subsidiary, plus $17.6M of other income.

Operating performance improved meaningfully as research and development expenses fell from $56.6M to $11.9M, while selling, general and administrative costs rose but remained manageable. The net loss attributable to common stockholders narrowed sharply to $1.9M, or $(0.07) per share, versus $55.9M previously.

Strategically, the FDA approval of ZYCUBO and the $205M PRV sale generated substantial cash and set up future tiered royalties and up to approximately $128M in milestones from Sentynl. Additional upside could come from the $4.8M contingent value right and 2.5% UNLOXCYT royalty, plus a 3% royalty on dotinurad. These deal-linked streams, alongside improved equity of $62.2M, position Fortress with a more robust balance sheet, though actual cash realization will depend on partner commercial performance.

Item 2.02 Results of Operations and Financial Condition Financial
Disclosure of earnings results, typically an earnings press release or preliminary financials.
Item 9.01 Financial Statements and Exhibits Exhibits
Financial statements, pro forma financial information, and exhibit attachments filed with this report.
Net revenue $63.3M Year ended December 31, 2025 (vs. $57.7M in 2024)
Net income attributable to Fortress $6.8M Year ended December 31, 2025 (vs. -$46.0M in 2024)
Net loss to common stockholders $1.9M Year ended December 31, 2025; $(0.07) per share
PRV sale proceeds $205M Gross proceeds from Cyprium’s sale of Rare Pediatric Disease PRV
Potential ZYCUBO milestones $128M Approximate aggregate sales milestones from Sentynl Therapeutics
Gain from deconsolidation $27.1M Gain from deconsolidation of subsidiary in 2025
Cash and cash equivalents $79.4M Balance at December 31, 2025
Total stockholders’ equity $62.2M At December 31, 2025 (vs. -$1.6M in 2024)
Rare Pediatric Disease Priority Review Voucher regulatory
"sold its Rare Pediatric Disease Priority Review Voucher (PRV) for gross proceeds of $205 million"
A rare pediatric disease priority review voucher is a transferable regulatory benefit awarded to a company that wins approval for a drug treating a serious but uncommon childhood illness. It works like a “fast-pass” with regulators: the holder can use it to get an accelerated review of a future drug application or sell the voucher to another company, often for a large sum. Investors care because it can speed time to market or generate immediate cash, boosting potential returns and lowering risk on other programs.
contingent value right financial
"remains eligible to receive up to an additional $4.8 million under a contingent value right (CVR)"
A contingent value right is a special security that gives its holder the right to receive one or more future payments only if specified events happen, such as a product reaching a sales target or getting regulatory approval. It matters to investors because it offers potential extra payout tied to uncertain outcomes—like a bet that a project will succeed—so it can add upside to a deal while also carrying extra risk and valuation uncertainty.
non-controlling interests financial
"Attributable to non-controlling interests | 39,730 | 74,858"
An ownership stake in a subsidiary held by outside shareholders rather than the parent company, representing the portion of that subsidiary’s assets and profits the parent does not control. For investors, it shows what part of consolidated earnings and equity belongs to others — like a roommate who owns part of a house — which affects how much value and profit per share are truly attributable to the parent company’s shareholders.
Phase 3 medical
"the progression of dotinurad into Phase 3 by Crystalys Therapeutics"
Phase 3 is the late-stage clinical testing step for a new drug or medical treatment, where the product is given to large groups of patients to confirm effectiveness, monitor side effects, and compare it to standard care. Successful Phase 3 results are often the final scientific hurdle before regulators decide on approval and market launch—like passing a final exam before graduation—and can sharply change a company's valuation and future revenue prospects.
Net loss per common share financial
"Net loss per common share attributable to common stockholders - basic & diluted"
Net loss per common share is the amount of money a company lost during a reporting period allocated to each outstanding common share after subtracting all expenses, taxes and obligations owed to preferred shareholders. Investors use it like a per-share scorecard to see how much value the company destroyed for ordinary shareholders during that period; a larger negative number signals greater erosion of shareholder value and can affect stock price and future financing options.
redeemable perpetual preferred financial
"Cumulative redeemable perpetual preferred stock, $0.001 par value"
Offering Type earnings_snapshot
0001429260false0001429260us-gaap:CommonStockMember2026-03-312026-03-310001429260fbio:SeriesCumulativeRedeemablePerpetualPreferredStockMember2026-03-312026-03-3100014292602026-03-312026-03-31

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, D.C. 20549

FORM 8-K

CURRENT REPORT

Pursuant to Section 13 or 15(d) of the

Securities Exchange Act of 1934

Date of report (Date of earliest event reported): March 31, 2026

Fortress Biotech, Inc.

(Exact Name of Registrant as Specified in Charter)

Delaware
 (State or Other Jurisdiction
of Incorporation)

  ​ ​

001-35366
 (Commission File Number)

  ​ ​ ​

20-5157386
(IRS Employer
Identification No.)

1111 Kane Concourse, Suite 301

Bay Harbor IslandsFL 33154

(Address of Principal Executive Offices)

(781652-4500

(Registrant’s telephone number, including area code)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

Written communications pursuant to Rule 425 under the Securities Act.

Soliciting material pursuant to Rule 14a-12 under the Exchange Act.

Pre-commencement communications pursuant to Rule 14d-2b under the Exchange Act.

Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act.

Securities registered pursuant to Section 12(b) of the Act:

Title of each class

Trading Symbol(s)

Name of each exchange on which registered

Common Stock

FBIO

Nasdaq Capital Market

9.375% Series A Cumulative Redeemable Perpetual Preferred Stock

FBIOP

Nasdaq Capital Market

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act.

Item 2.02.    Results of Operations and Financial Condition.

On March 31, 2026, Fortress Biotech, Inc. issued a press release to provide a corporate update and to announce its financial results for the year ended December 31, 2025. A copy of such press release is being furnished as Exhibit 99.1 to this report.

 

The information, including Exhibit 99.1, in this Form 8-K is being furnished and shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liabilities of that Section. The information in this Form 8-K shall not be incorporated by reference into any filing under the Securities Act of 1933, as amended, except as shall otherwise be expressly set forth by specific reference in such filing.

Item 9.01.    Financial Statements and Exhibits.

(d)    Exhibits.

The following exhibit is furnished herewith:

99

Exhibit
Number

  ​ ​ ​

Description

99.1

 

Press Release, dated March 31, 2026

104

 

Cover Page Interactive Data File (the cover page XBRL tags are imbedded in the Inline XBRL document)

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, as amended, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

Fortress Biotech, Inc.

(Registrant)

Date: March 31, 2026

 

By:

/s/ David Jin

 

 

David Jin

 

 

Chief Financial Officer

Exhibit 99.1

Graphic

Fortress Biotech Reports 2025 Financial Results and Recent Corporate Highlights

ZYCUBO® approved by FDA to treat Menkes disease in the United States; Fortress subsidiary Cyprium Therapeutics sold its Rare Pediatric Disease Priority Review Voucher (PRV) for gross proceeds of $205 million; Cyprium is also eligible to receive tiered royalties and up to approximately $128 million in aggregate sales milestones from Sentynl Therapeutics

Fortress subsidiary Checkpoint Therapeutics acquired by Sun Pharma; Fortress remains eligible to receive up to an additional $4.8 million under a contingent value right (CVR), plus a 2.5% royalty on net sales of UNLOXCYT™ (cosibelimab-ipdl)

Miami, FL – March 31, 2026 – Fortress Biotech, Inc. (Nasdaq: FBIO) (“Fortress”), an innovative biopharmaceutical company focused on acquiring and advancing assets to enhance long-term value for shareholders through product revenue, equity holdings and dividend and royalty income, today announced financial results and recent corporate highlights for the full-year ended December 31, 2025.

Lindsay A. Rosenwald, M.D., Fortress’ Chairman, President and Chief Executive Officer, said, “2025 and early 2026 reflect disciplined execution across our portfolio, including monetizing assets, achieving key regulatory approvals and advancing high-value clinical programs. The acquisition of Checkpoint Therapeutics, Inc. (“Checkpoint”) by Sun Pharma generated meaningful upfront capital and established a long-term royalty stream from UNLOXCYT™ (cosibelimab-ipdl), highlighting the strength of our business model. The FDA approval of ZYCUBO® for Menkes disease, followed by the recent sale of the Rare Pediatric Disease Priority Review Voucher (“PRV”) for $205 million by our majority-owned subsidiary Cyprium Therapeutics, Inc. (“Cyprium”), demonstrates our continued ability to advance our portfolio toward value-generating approvals and corporate transactions. Additionally, the progression of dotinurad into Phase 3 by Crystalys Therapeutics, to which we transferred rights to dotinurad in exchange for equity in Crystalys and a 3% royalty on dotinurad sales, supported by its Series A $205 million financing, further validates our strategy of building diversified revenue streams and creating long-term shareholder value.”

Recent Corporate Highlights1:

Regulatory Updates

ZYCUBO® Approved for Menkes Disease; Cyprium Sold PRV for $205 Million; Royalty and Milestone Participation Secured. In January 2026, the FDA approved ZYCUBO® (copper histidinate, formerly known as CUTX-101) for the treatment of Menkes disease in pediatric patients. A PRV was issued at approval and transferred to Cyprium under its agreement with Sentynl Therapeutics, Inc. (“Sentynl”). In March 2026, Cyprium closed the sale of the PRV for gross proceeds of $205 million. Cyprium is also eligible to receive tiered royalties on net sales of

1 This press release references products being developed or commercialized by Fortress, by Fortress’ private or public subsidiaries (referred to herein as “subsidiaries” or “partner companies”) and by entities with whom one of the foregoing parties has a significant business relationship, such as an exclusive license or an ongoing product-related payment obligation (such entities referred to herein as “partners”). The words “we”, “us” and “our” may refer to Fortress individually, to one or more of our subsidiaries and/or partner companies, or to all such entities as a group, as dictated by context.


ZYCUBO® and up to approximately $128 million in aggregate sales milestones from Sentynl. ZYCUBO® was commercially launched by Sentynl subsequent to approval.
oIn connection with the sale of the PRV, Cyprium redeemed all outstanding shares of its 9.375% Perpetual Preferred Stock pursuant to the previously disclosed terms of such securities.
oIn total, Fortress expects to receive an aggregate of at least $100 million from Cyprium pursuant to potential future dividends and intercompany agreements, including amounts owed by Cyprium to Fortress through intercompany debt, interest and accrued expenses. The amount Fortress will receive is subject to change based on various considerations including, but not limited to, Cyprium’s obligation to pay 20% of the proceeds from a PRV sale to an institute of the National Institutes of Health, Cyprium’s tax obligations on the income received from the PRV sale, any future dividends that may be approved by Cyprium’s Board of Directors, and Cyprium’s outstanding and future obligations.

Monetization Updates

Checkpoint Acquired by Sun Pharma; Fortress Establishes Long-Term Royalty Stream. In May 2025, Fortress’ subsidiary, Checkpoint, was acquired by Sun Pharmaceutical Industries, Inc. (together with its subsidiaries and/or associated companies, “Sun Pharma”). Checkpoint was acquired for an aggregate upfront payment totaling ~$355 million and ~$60 million payable in a contingent value right (“CVR”), of which Fortress received ~$28 million upfront, with the potential for an additional CVR payment of up to $4.8 million and a 2.5% royalty on future net sales of UNLOXCYT (cosibelimab-ipdl). UNLOXCYT™ was approved by the FDA in December 2024 to treat metastatic or locally advanced cutaneous squamous cell carcinoma (“cSCC”) in patients who are not candidates for curative surgery or radiation and was commercially launched in January 2026.
Avenue Therapeutics’ Subsidiary Baergic Acquired by Axsome. In November 2025, Avenue Therapeutics, Inc.’s (“Avenue”) subsidiary Baergic Bio, Inc. (“Baergic”) was acquired by Axsome Therapeutics (“Axsome”). Under the terms of the purchase agreement, Baergic shareholders received a $0.3 million upfront payment (less transaction expenses) and are eligible to receive milestone payments of up to $2.5 million upon the occurrence of certain development and regulatory events for the first indication for AXS-17 (formerly known as BAER-101). Avenue, a Fortress subsidiary, is eligible to receive approximately 74% of all future milestone and royalty payments under the agreement, including up to $79 million in potential sales milestones and tiered mid-to-high single-digit royalties.
$205 Million Series A Raised by Crystalys to Advance Dotinurad Phase 3 Program. In the third quarter of 2025, Crystalys Therapeutics (“Crystalys”), in which our majority-owned and controlled subsidiary company Urica Therapeutics, Inc. (“Urica”), maintains an equity position, announced a $205 million Series A financing to support two global Phase 3 clinical studies evaluating dotinurad for gout. Urica is eligible to receive a 3% royalty on future net sales of dotinurad. Urica entered into an asset purchase agreement, royalty agreement and related agreements with Crystalys in July 2024.

Commercial Product Updates

Journey Medical Expands Commercial Footprint of Emrosi. At the end of March 2025, our partner company Journey Medical Corporation (“Journey Medical”), commercially launched Emrosi™ (40mg Minocycline Hydrochloride Modified-Release Capsules, consisting of 10mg immediate release and 30mg extended release pellets), also known as DFD-29, for inflammatory lesions of rosacea. Emrosi™ was approved by the FDA in November 2024 and is available by prescription at specialty pharmacy chains. Journey Medical reported net product revenues of $61.2 million for full-year 2025, compared to net product revenues of $55.1 million for the full year ended December 31, 2024.

Clinical Updates

Dotinurad Enters Phase 3 Development. In October 2025, the first patients were dosed in Crystalys’ two randomized, double-blind, multicenter global Phase 3 trials evaluating dotinurad, a next-generation, once daily oral, URAT1 inhibitor with potential for best-in-class safety and efficacy for the treatment of gout.
Phase 3 CARES Results for Anselamimab (CAEL-101); Regulatory Submission of Prespecified Subgroup Analysis Planned. In July 2025, AstraZeneca announced that anselamimab (formerly known as CAEL-101) did not achieve statistical significance for the primary endpoint in its Phase III Cardiac Amyloid Reaching for Extended Survival (“CARES”) clinical program for Mayo stages IIIa and IIIb AL amyloidosis patients. However, the drug showed


clinically meaningful improvement in a prespecified subgroup and was well tolerated. AstraZeneca indicated that the company plans to submit the prespecified subgroup analysis from the CARES trials to regulatory authorities.
Emrosi™ Phase 3 Data Published in JAMA Dermatology and Journal of Drugs in Dermatology. In March 2025, full results from two Phase 3 multicenter, randomized, double-blind, parallel-group, active-comparator and placebo-controlled clinical trials, Minocycline Versus Oracea® in Rosacea-1 (“MVOR-1”) and Minocycline Versus Oracea® in Rosacea-2 (“MVOR-2”), evaluating Emrosi™ for the treatment of moderate-to-severe papulopustular rosacea in adults, were published in the Journal of the American Medical Association - Dermatology. The results demonstrated the efficacy, safety and tolerability of oral DFD-29 in rosacea. The full publication is available at https://jamanetwork.com/journals/jamadermatology/article-abstract/2830693. Information on such website is not a part of this release. In December 2025, results from the Phase 1 clinical trial (DFD-29-CD-006) assessing the impact of low-dose oral minocycline (commercially known as Emrosi™) on skin, gastrointestinal (“GI”) and vaginal microflora in healthy adults were published in the Journal of Drugs in Dermatology. The clinical trial also assessed the safety and tolerability of the treatment. The results indicate that DFD-29 administration for 16 weeks had no detectable effects on skin, GI tract or vaginal microflora and it was well tolerated in healthy adults, supporting its use as a therapeutic option for patients with moderate-to-severe rosacea.
Emrosi™ Phase 3 Results Presented at Scientific Meetings. In June 2025, a data analysis from the two Phase 3 multicenter clinical trials evaluating Emrosi™ for the treatment of moderate-to-severe papulopustular rosacea in adults was presented at the Society of Dermatology Physician Associates 2025 Summer Dermatology Conference. The analysis determined that differences in body weight did not affect the efficacy of Emrosi™ in the two Phase 3 trials, which supported its November 2024 FDA approval. In October 2025, efficacy data from a pooled analysis of the MVOR-1 and MVOR-2 trials were presented at the 2025 Fall Clinical Dermatology Conference and demonstrated superior efficacy in Investigator’s Global Assessment treatment success rates and inflammatory lesion counts versus both placebo and doxycycline (P<0.001 for all comparisons).
Triplex CMV Vaccine Phase 2 Update. In January 2025, the first patient was dosed in a multicenter, placebo-controlled and randomized Phase 2 clinical trial to evaluate Triplex, a cytomegalovirus (“CMV”) vaccine, when administered to human leukocyte antigen matched related stem cell donors to reduce CMV events in patients undergoing hematopoietic stem cell transplantation. Triplex is being investigated in eight clinical trials and is currently in development at our subsidiary company, Helocyte, Inc.

General Corporate:

In March 2026, Fortress made aggregate prepayments on its loan with Oaktree, including a prepayment in connection with the sale of the PRV, reducing the outstanding principal balance to $15.0 million.
In February 2026, Avenue entered into an exclusive worldwide license agreement with Duke University to acquire patent and know-how rights pertaining to ATX-04 (clenbuterol), a well-characterized small-molecule β2-adrenergic agonist, in clinical development for the treatment of Pompe disease. ATX-04 is a selective β2-adrenergic agonist with human proof-of-concept data demonstrating improved muscle function and enhanced response to enzyme replacement therapy. Avenue anticipates meeting with the FDA in 2026 to discuss and align on the design of a potential single pivotal trial for ATX-04 for Pompe disease.
Journey Medical joined the small-cap Russell 2000® and the broad-market Russell 3000® Indexes, in June 2025.

Financial Results:

As of December 31, 2025, Fortress’ consolidated cash and cash equivalents totaled $79.4 million, compared to $86.2 million as of September 30, 2025, and $57.3 million as of December 31, 2024, a decrease of $6.8 million for the fourth quarter and an increase of $22.1 million for the full year.
Fortress’ consolidated cash and cash equivalents totaled $79.4 million as of December 31, 2025, and includes $35.2 million attributable to Fortress and private subsidiaries, $2.9 million attributable to Avenue, $17.3 million attributable to Mustang and $24.1 million attributable to Journey Medical. Checkpoint was acquired by Sun Pharma in May 2025.
Fortress’ consolidated net revenue totaled $63.3 million for the full year ended December 31, 2025, which included $61.2 million in net revenue generated from our marketed dermatology products. This compares to


consolidated net revenue totaling $57.7 million for the full year ended 2024, which included $55.1 million in net revenue generated from our marketed dermatology products.
Consolidated research and development expenses including license acquisitions totaled $11.9 million for the full year ended December 31, 2025, compared to $56.9 million for the full year ended December 31, 2024.
Consolidated selling, general and administrative costs were $96.4 million for the full year ended December 31, 2025, compared to $87.7 million for the full year ended December 31, 2024.
Consolidated net loss attributable to common stockholders was $(1.9) million, or $(0.07) per share, for the full year ended December 31, 2025, compared to net loss attributable to common stockholders of $(55.9) million, or $(2.69) per share for the full year ended December 31, 2024.

About Fortress Biotech

Fortress Biotech, Inc. (“Fortress”) is an innovative biopharmaceutical company focused on acquiring and advancing assets to enhance long-term value for shareholders through product revenue, equity holdings and dividend and royalty income. The company has a portfolio of multiple marketed prescription pharmaceutical products and programs in development at Fortress, at its majority-owned and majority-controlled partners and subsidiaries and at partners and subsidiaries it founded and in which it holds significant minority ownership positions. Fortress’ portfolio is being commercialized and developed for various therapeutic areas including oncology, dermatology, and rare diseases. Fortress’ model is focused on leveraging its significant biopharmaceutical industry expertise and network to further expand and advance the company’s portfolio of product opportunities. Fortress has established partnerships with some of the world’s leading academic research institutions and biopharmaceutical companies to maximize each opportunity to its full potential, including AstraZeneca, City of Hope, Nationwide Children’s Hospital, Columbia University, Dana-Farber Cancer Center and Sentynl Therapeutics. For more information, visit www.fortressbiotech.com.

Forward-Looking Statements

Statements in this press release that are not descriptions of historical facts are “forward-looking statements” within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934, as amended. The words “anticipates,” “believes,” “can,” “continue,” “could,” “estimates,” “expects,” “intends,” “may,” “might,” “plans,” “potential,” “predicts,” “should,” or “will” or the negative of these terms or other comparable terminology are generally intended to identify forward-looking statements. These forward-looking statements are based on management’s current expectations and are subject to risks and uncertainties that could negatively affect our business, operating results, financial condition and stock price. Factors that could cause actual results to differ materially from those currently anticipated include risks relating to: our growth strategy, financing and strategic agreements and relationships; our need for substantial additional funds and uncertainties relating to financings; uncertainty related to the timing and amounts expected to be realized from future milestone, contingent value right, royalty or similar future revenue streams, if at all; our ability to identify, acquire, close and integrate product candidates successfully and on a timely basis; our ability to attract, integrate and retain key personnel; the early stage of product candidates under development; the results of research and development activities; uncertainties relating to preclinical and clinical testing; our ability to obtain regulatory approval for products under development; our ability to successfully commercialize products for which we receive regulatory approval or receive royalties or other distributions from third parties; our ability to secure and maintain third-party manufacturing, marketing and distribution of our and our partner companies’ products and product candidates; government regulation; patent and intellectual property matters; competition; as well as other risks described in our SEC filings. We expressly disclaim any obligation or undertaking to release publicly any updates or revisions to any forward-looking statements contained herein to reflect any change in our expectations or any changes in events, conditions or circumstances on which any such statement is based, except as may be required by law, and we claim the protection of the safe harbor for forward-looking statements contained in the Private Securities Litigation Reform Act of 1995. The information contained herein is intended to be reviewed in its totality, and any stipulations, conditions or provisos that apply to a given piece of information in one part of this press release should be read as applying mutatis mutandis to every other instance of such information appearing herein.

Company Contact:

Jaclyn Jaffe

Fortress Biotech, Inc.

(781) 652-4500


ir@fortressbiotech.com

Media Relations Contact:

Tony Plohoros

6 Degrees

(908) 591-2839

tplohoros@6degreespr.com


FORTRESS BIOTECH, INC. AND SUBSIDIARIES

Consolidated Balance Sheets

($ in thousands except for share and per share amounts)

December 31, 

December 31, 

2025

2024

ASSETS

 

 

  ​

Current assets

 

  ​

 

  ​

Cash and cash equivalents

$

79,381

$

57,263

Accounts receivable, net

 

29,783

 

10,231

Inventory

 

9,624

 

14,431

Other receivables - related party

 

158

 

171

Prepaid expenses and other current assets

 

4,895

 

7,110

Assets held for sale

 

 

1,165

Total current assets

 

123,841

 

90,371

Property, plant and equipment, net

 

2,519

 

3,260

Operating lease right-of-use asset, net

 

12,302

 

13,861

Restricted cash

 

1,220

 

1,552

Equity investments, at fair value

 

17,660

 

2,585

Intangible assets, net

 

27,605

 

31,863

Other assets

 

401

 

731

Total assets

$

185,548

$

144,223

LIABILITIES AND STOCKHOLDERS’ EQUITY (DEFICIT)

 

  ​

 

  ​

Current liabilities

 

 

Accounts payable and accrued expenses

$

47,125

$

65,501

Income taxes payable

356

932

Common stock warrant liabilities

1

214

Operating lease liabilities, short-term

 

2,127

 

2,623

Partner company installment payments - licenses, short-term

625

Other current liabilities

135

1,504

Total current liabilities

 

49,744

 

71,399

Notes payable, long-term, net

 

52,417

 

57,962

Operating lease liabilities, long-term

 

12,672

 

14,750

Partner company redeemable perpetual preferred liability

7,085

Other long-term liabilities

 

1,447

 

1,756

Total liabilities

123,365

145,867

 

 

Commitments and contingencies

 

  ​

 

  ​

Stockholders’ equity (deficit)

 

  ​

 

  ​

Cumulative redeemable perpetual preferred stock, $0.001 par value, 15,000,000 authorized, 5,000,000 designated Series A shares, 3,427,138 shares issued and outstanding as of December 31, 2025 and December 31, 2024, respectively, liquidation value of $25.00 per share

 

3

 

3

Common stock, $0.001 par value, 200,000,000 shares authorized, 31,364,094 and 27,908,839 shares issued and outstanding as of December 31, 2025 and December 31, 2024, respectively

 

31

 

28

Additional paid-in-capital

 

783,891

 

763,573

Accumulated deficit

 

(734,052)

 

(740,867)

Total stockholders' equity attributed to the Company

 

49,873

 

22,737

Non-controlling interests

 

12,310

 

(24,381)

Total stockholders' equity (deficit)

 

62,183

 

(1,644)

Total liabilities and stockholders' equity (deficit)

$

185,548

$

144,223


FORTRESS BIOTECH, INC. AND SUBSIDIARIES

Consolidated Statements of Operations

($ in thousands except for share and per share amounts)

Year Ended December 31, 

  ​ ​ ​

2025

  ​ ​ ​

2024

Revenue

 

  ​

 

  ​

Product revenue, net

$

61,239

$

55,134

Collaboration revenue

1,500

Revenue - related party

 

 

41

Other revenue

2,023

1,000

Net revenue

 

63,262

 

57,675

Operating expenses

 

 

Cost of goods - (excluding amortization of acquired intangible assets)

 

20,924

 

20,879

Amortization of acquired intangible assets

4,258

 

3,424

Research and development

 

11,901

 

56,629

Research and development - licenses acquired

 

 

252

Selling, general and administrative

 

96,400

 

87,731

Loss recovery

(4,553)

Asset impairment

3,692

Total operating expenses

 

133,483

 

168,054

Loss from operations

 

(70,221)

 

(110,379)

Other income (expense)

 

  ​

 

  ​

Interest income

 

2,485

 

2,683

Interest expense and financing fee

 

(10,106)

 

(13,527)

Loss on common stock warrant liabilities

 

(398)

 

(638)

Gain from deconsolidation of subsidiary

27,127

Other income

17,578

1,318

Total other income (expense)

 

36,686

 

(10,164)

Loss before income tax expense

(33,535)

(120,543)

Income tax expense (benefit)

 

(620)

 

312

Net loss

 

(32,915)

 

(120,855)

Attributable to non-controlling interests

 

39,730

 

74,858

Net income (loss) attributable to Fortress

$

6,815

$

(45,997)

Preferred A dividends declared and paid and/or cumulated, and Fortress' share of subsidiary deemed dividends

(8,697)

(9,893)

Net loss attributable to common stockholders

$

(1,882)

$

(55,890)

Net loss per common share attributable to common stockholders - basic & diluted

$

(0.07)

$

(2.69)

Weighted average common shares outstanding - basic & diluted

 

27,901,889

 

20,784,334


FAQ

How did Fortress Biotech (FBIO) perform financially in 2025?

Fortress Biotech reported net revenue of $63.3 million for 2025, up from $57.7 million in 2024. Net income attributable to Fortress was $6.8 million, a sharp improvement from a $46.0 million loss, while net loss attributable to common stockholders narrowed to $1.9 million.

What major transaction did Fortress Biotech’s Cyprium subsidiary complete in 2026?

Cyprium sold a Rare Pediatric Disease Priority Review Voucher for gross proceeds of $205 million. In addition, Cyprium is eligible to receive tiered royalties on ZYCUBO net sales and up to approximately $128 million in aggregate sales milestones from Sentynl Therapeutics.

What is the significance of ZYCUBO’s FDA approval for Fortress Biotech (FBIO)?

The FDA approved ZYCUBO to treat Menkes disease in pediatric patients, triggering issuance of a Priority Review Voucher later sold for $205 million. ZYCUBO has been commercially launched by Sentynl, and Cyprium may earn tiered royalties and substantial sales milestones.

How does the Checkpoint Therapeutics acquisition impact Fortress Biotech?

Sun Pharma acquired Fortress subsidiary Checkpoint Therapeutics, and Fortress remains eligible to receive up to an additional $4.8 million under a contingent value right. Fortress is also entitled to a 2.5% royalty on net sales of UNLOXCYT (cosibelimab-ipdl).

How strong was Fortress Biotech’s balance sheet at year-end 2025?

At December 31, 2025, Fortress Biotech reported total assets of $185.5 million, including $79.4 million in cash and cash equivalents. Total stockholders’ equity improved to $62.2 million, reversing a stockholders’ deficit of $1.6 million at the end of 2024.

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