Frazier Life Sciences II insider buys 300,000 shares

Frazier Life Sciences Acquisition Corp. II (FLSC) reported that Frazier Life Sciences Holdings II LLC purchased 300,000 Class A ordinary shares at $10.00 per share on October 15, 2026; the LLC reported 300,000 shares following the transaction.

Rhea-AI Filing Summary

Frazier Life Sciences Acquisition Corp. II (FLSC) reported that Frazier Life Sciences Holdings II LLC purchased 300,000 Class A ordinary shares at $10.00 per share on October 15, 2026; the LLC reported 300,000 shares following the transaction. Albert Cha, listed as Chief Executive Officer, director and 10% owner, is identified as the LLC’s sole manager. Frazier Life Sciences Holdings II LLC, Frazier Life Sciences Public Fund, L.P., FHMLSP, L.P. and FHMLSP, L.L.C. are each listed as 10% owners; the footnote describes the fund and general-partner ownership chain. The reporting persons disclaim beneficial ownership except to the extent of their pecuniary interest, if any. No Rule 10b5-1 plan is reported.

Insider Trade Summary

Net Buyer: 300,000 shares

Net Buy 1 txn

Insider Cha Albert, Frazier Life Sciences Holdings II LLC, Frazier Life Sciences Public Fund, L.P., FHMLSP, L.P., FHMLSP, L.L.C.

Role Chief Executive Officer | 10% Owner | 10% Owner | 10% Owner | 10% Owner

Bought 300,000 shs ($3.00M)

Type	Security	Shares	Price	Value
Purchase	Class A ordinary shares F1	300,000	$10.00	$3.00M

Holdings After Transaction: Class A ordinary shares — 300,000 shares (Indirect, By Frazier Life Sciences Holdings II LLC)

Footnotes (1)

1. F1. Securities held by Frazier Life Sciences Holdings II LLC ("Sponsor"). Albert Cha is the sole manager of Sponsor, and Frazier Life Sciences Public Fund, L.P. is its sole equity holder. FHMLSP, L.P. is the general partner of Frazier Life Sciences Public Fund, L.P. and FHMLSP, L.L.C. is the general partner of FHMLSP, L.P. The Reporting Persons disclaim beneficial ownership of such shares except to the extent of its or his pecuniary interest therein, if any.

Key Figures

Shares purchased: 300,000 shares Purchase price: $10.00 per share Shares following transaction: 300,000 shares

3 metrics

Shares purchased 300,000 shares Purchased by Frazier Life Sciences Holdings II LLC on October 15, 2026

Purchase price $10.00 per share Purchase on October 15, 2026

Shares following transaction 300,000 shares Reported by Frazier Life Sciences Holdings II LLC

Key Terms

Class A ordinary shares, beneficial ownership, pecuniary interest, general partner

4 terms

Class A ordinary shares financial

"Class A ordinary shares"

Class A ordinary shares are a type of ownership stake in a company that typically grants voting rights to shareholders, allowing them to have a say in important company decisions. They often come with priority in receiving dividends or profits, making them attractive to investors seeking influence and potential income. These shares help distinguish different levels of ownership and rights within a company's stock structure.

beneficial ownership financial

"disclaim beneficial ownership of such shares"

Beneficial ownership means the person or entity that actually enjoys the benefits of owning shares or other assets — such as receiving dividends, voting rights, or price gains — even if the legal title is held in another name. For investors it matters because knowing who truly controls and profits from a company reveals who can influence decisions, exposes potential conflicts of interest or hidden concentration of power, and affects transparency and risk in the stock.

pecuniary interest financial

"pecuniary interest therein, if any"

general partner financial

"FHMLSP, L.P. is the general partner"

A general partner is the person or firm that runs an investment partnership and legally represents it — they make the day-to-day decisions, choose which assets to buy or sell, and are responsible for the partnership’s obligations. Investors care because the general partner’s judgment, risk-taking and fee and profit-sharing arrangements determine both the potential returns and the level of exposure to losses; think of the GP as the ship’s captain whose skill and honesty shape the voyage’s outcome.

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

How many FLSC shares did Frazier Life Sciences Holdings II LLC buy, and at what price?

Frazier Life Sciences Holdings II LLC purchased 300,000 Class A ordinary shares at $10.00 per share on October 15, 2026. It reported 300,000 shares following the transaction, and no Rule 10b5-1 plan is reported.

AI-generated analysis. How Rhea-AI works. Not financial advice.

Form 4 Insider Transactions: What Each Field Means →

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Available on EDGAR 10/15/2026 - 04:40 PM EDT Accepted by SEC EDGAR 10/15/2026 - 04:40 PM EDT Learn about SEC filing dates

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Cha Albert

(Last) (First) (Middle)

1001 PAGE MILL ROAD

BUILDING 4, SUITE 200B

(Street)

PALO ALTO CALIFORNIA 93404

(City) (State) (Zip)

UNITED STATES

(Country)

2. Issuer Name and Ticker or Trading Symbol
Frazier Life Sciences Acquisition Corp. II [ FLSC ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director	X	10% Owner
X	Officer (give title below)		Other (specify below)
	Chief Executive Officer

2a. Foreign Trading Symbol

3. Date of Earliest Transaction (Month/Day/Year)
10/15/2026

6. Individual or Joint/Group Filing (Check Applicable Line)

	Form filed by One Reporting Person
X	Form filed by More than One Reporting Person

4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Class A ordinary shares	10/15/2026		P		300,000	A	$10	300,000	I	By Frazier Life Sciences Holdings II LLC(1)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

1. Name and Address of Reporting Person^*

Cha Albert

(Last) (First) (Middle)

1001 PAGE MILL ROAD

BUILDING 4, SUITE 200B

(Street)

PALO ALTO CALIFORNIA 93404

(City) (State) (Zip)

UNITED STATES

(Country)

Relationship of Reporting Person(s) to Issuer

X	Director	X	10% Owner
X	Officer (give title below)		Other (specify below)
	Chief Executive Officer

1. Name and Address of Reporting Person^*

Frazier Life Sciences Holdings II LLC

(Last) (First) (Middle)

1001 PAGE MILL ROAD

BUILDING 4, SUITE 200B

(Street)

PALO ALTO CALIFORNIA 93404

(City) (State) (Zip)

UNITED STATES

(Country)

Relationship of Reporting Person(s) to Issuer

	Director	X	10% Owner
	Officer (give title below)		Other (specify below)

1. Name and Address of Reporting Person^*

Frazier Life Sciences Public Fund, L.P.

(Last) (First) (Middle)

1001 PAGE MILL ROAD

BUILDING 4, SUITE 200B

(Street)

PALO ALTO CALIFORNIA 93404

(City) (State) (Zip)

UNITED STATES

(Country)

Relationship of Reporting Person(s) to Issuer

	Director	X	10% Owner
	Officer (give title below)		Other (specify below)

1. Name and Address of Reporting Person^*

FHMLSP, L.P.

(Last) (First) (Middle)

1001 PAGE MILL ROAD

BUILDING 4, SUITE 200B

(Street)

PALO ALTO CALIFORNIA 93404

(City) (State) (Zip)

UNITED STATES

(Country)

Relationship of Reporting Person(s) to Issuer

	Director	X	10% Owner
	Officer (give title below)		Other (specify below)

1. Name and Address of Reporting Person^*

FHMLSP, L.L.C.

(Last) (First) (Middle)

1001 PAGE MILL ROAD

BUILDING 4, SUITE 200B

(Street)

PALO ALTO CALIFORNIA 93404

(City) (State) (Zip)

UNITED STATES

(Country)

Relationship of Reporting Person(s) to Issuer

	Director	X	10% Owner
	Officer (give title below)		Other (specify below)

Explanation of Responses:

1. Securities held by Frazier Life Sciences Holdings II LLC ("Sponsor"). Albert Cha is the sole manager of Sponsor, and Frazier Life Sciences Public Fund, L.P. is its sole equity holder. FHMLSP, L.P. is the general partner of Frazier Life Sciences Public Fund, L.P. and FHMLSP, L.L.C. is the general partner of FHMLSP, L.P. The Reporting Persons disclaim beneficial ownership of such shares except to the extent of its or his pecuniary interest therein, if any.

	/s/ Albert Cha	10/15/2026
	FRAZIER LIFE SCIENCES HOLDINGS II LLC, By: /s/ Albert Cha, Manager	10/15/2026
	FRAZIER LIFE SCIENCES PUBLIC FUND, L.P., By: /s/ Albert Cha, Managing Member of General Partner of General Partner	10/15/2026
	FHMLSP, L.P., By: /s/ Albert Cha, Managing Member of General Partner	10/15/2026
	FHMLSP, L.L.C., By: /s/ Albert Cha, Managing Member	10/15/2026
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)