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Lakefront Biotherapeutics NV (GLPGF) SEC Filings, Mar-Jun 2026

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Lakefront Biotherapeutics reported progress under its previously announced share repurchase program, buying back 77,667 ordinary shares between 15 and 19 June 2026. The company paid an average of €24.6586 per share, for a total consideration of €1,915,162.13 across Euronext trades during this period.

After these transactions, Lakefront held 116,204 of its own ordinary shares as of market close on 19 June 2026. The company reiterates that repurchases form part of its capital management strategy, while also reminding investors that any plans to repurchase shares involve forward-looking statements and are subject to various risks and uncertainties described in its SEC filings.

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Madison Avenue-affiliated investors report beneficial ownership of 3,606,203 Ordinary Shares of Lakefront Biotherapeutics. The Schedule 13G states the group (Madison Avenue International LP, Madison Avenue Partners LP, EMAI Management, Madison Avenue GP, Caraway Jackson Investments LLC and Eli Samaha) may be deemed to beneficially own 3,606,203 shares as of June 23, 2026, representing approximately 5.5% of the class based on 65,897,071 Ordinary Shares outstanding as of December 31, 2025. The filing lists shared voting and dispositive power of 3,606,203 shares across the reporting persons and includes a Joint Filing Agreement. The reporting persons disclaim beneficial ownership except to the extent of pecuniary interest.

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Lakefront Biotherapeutics reported that, under its share repurchase program announced on June 9, 2026, it bought back 38,537 ordinary shares between June 9 and June 12, 2026. The shares were repurchased at an average price of €24.7764, for a total of €954,808.90.

As of market close on June 12, 2026, Lakefront holds 38,537 of its own ordinary shares. The company describes itself as a biotechnology business with a clinical-stage portfolio in immunology and inflammation, including the BCMAxCD3 T-cell engager gamgertamig for autoimmune diseases.

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Lakefront Biotherapeutics announced a share repurchase program under which it may buy back ordinary shares for up to €50 million. The program runs until December 31, 2026 and is conducted through Morgan Stanley & Co International PLC, following terms approved at the April 28, 2026 Extraordinary Shareholders’ Meeting.

The company notes this is an initial step under a broader transaction with Gilead that allows repurchases of up to $150 million of shares, subject to distributable reserves. Repurchased shares will be held as treasury shares, and Lakefront can suspend or stop the program, with updates provided as required by law.

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Lakefront Biotherapeutics appointed Eric Hedrick, MD, as Chief Medical Officer, expanding its leadership team during a strategic transformation that follows the acquisition of Ouro Medicines’ operational assets announced on June 4, 2026.

Hedrick, who joined Lakefront in July 2025, has 25 years of experience developing successful therapies at several biotechnology companies. He will report to CEO Henry Gosebruch, join the Management Committee, and lead development of gamgertamig and future clinical programs within Lakefront’s oncology and immunology-focused R&D pipeline.

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Lakefront Biotherapeutics and Gilead Sciences have completed the acquisition of Ouro Medicines, adding the T cell engager gamgertamig (OM336) to their autoimmune pipelines. Gilead acquired all Ouro equity for $1,675 million plus up to $500 million in milestones, with Lakefront and Gilead splitting these payments equally.

Gamgertamig is a BCMAxCD3 T cell engager in Phase 2 with U.S. FDA Fast Track and Orphan Drug Designations and is expected to enter registrational studies as early as 2027. Lakefront takes on Phase 1/2 development while Gilead leads later-stage and commercialization, paying Lakefront tiered royalties of 20%–23% on net sales.

Lakefront also in-licensed three preclinical autoimmune programs with a Gilead opt-in for $75 million per program and a 50/50 profit split post proof-of-concept. The deal modifies the existing OLCA, allowing Lakefront to deploy at least $500 million of its cash independently, including up to $150 million for share buybacks, and the company expects a year-end 2026 cash balance of about €2B.

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Lakefront Biotherapeutics reported that Bank of America Corporation crossed a key ownership threshold under Belgian transparency rules. On May 13, 2026, Bank of America and its affiliates moved above 5% of Lakefront’s voting rights through a mix of shares and derivatives.

As of May 20, 2026, Bank of America held 623,434 direct voting rights and 5,502,802 equivalent financial instruments, together representing 9.30% of Lakefront’s currently outstanding 65,897,071 shares. The position is spread across several entities, including BofA Securities and Merrill Lynch International, via rights of use, recall, options, and swaps.

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Galapagos (to be renamed Lakefront Biotherapeutics) swung to profitability in Q1 2026 and unveiled a major autoimmune collaboration with Gilead. Net profit was €14.5 million versus a €153.4 million loss a year earlier, helped by €77.7 million in net financial income and much lower R&D and restructuring costs. Total net revenues fell to €6.5 million from €75.0 million as prior Gilead platform revenue fully ran off.

The company agreed a Framework Agreement linked to Gilead’s planned acquisition of Ouro Medicines, co-funding an upfront payment of $1.675 billion and up to $500 million in milestones, of which Galapagos’ share of the upfront is $837.5 million (~€713 million). Galapagos will co-develop BCMAxCD3 T cell engager gamgertamig and receive 20%–23% royalties on Gilead’s net sales.

Management guides 2026 Ouro-related cash spend of approximately €775–€790 million and expects year-end 2026 cash and financial investments of €1.975–€2.050 billion, down from €2.98 billion at March 31, 2026 but still leaving a majority of its current ~€3 billion cash for further deals and capital returns. The company is winding down its cell therapy activities, with one-time cash restructuring costs still expected at €125–€175 million, and will rebrand as Lakefront Biotherapeutics with new ticker LKFT from May 8, 2026.

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Galapagos NV reports that shareholders approved all agenda items at its Annual and Extraordinary Meetings, including the 2025 non-consolidated accounts, the remuneration report, and releases from liability for directors and the statutory auditor.

Shareholders confirmed and extended multiple board appointments, added new independent non-executive director Gino Santini as chair, and re-appointed BDO Bedrijfsrevisoren BV as statutory auditor with annual fees of EUR 495,000 plus EUR 50,000 for Corporate Sustainability Reporting Directive assurance. The company will change its name to Lakefront Biotherapeutics as of May 8, 2026, and amended its articles to require joint representation by two directors, including at least one independent director. The meetings also authorized a share buyback of up to 10% of outstanding shares within a 15% price band around the prior day’s Euronext Brussels closing price and renewed the Board’s authority to increase share capital by up to 20% over five years.

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Galapagos announced a binding collaboration framework with Gilead tied to Gilead’s planned $1.675 billion acquisition of Ouro Medicines, sharing both the $1.675 billion upfront consideration and up to $500 million in contingent milestones 50/50.

Galapagos will fund all gamgertamig development costs through the start of registrational studies, after which costs will be shared equally, and can earn up to $100 million in additional milestones for certain other indications plus tiered royalties of 20–23% on net sales. The company also gains three Ouro preclinical autoimmune programs, with Gilead holding an option to join each for $75 million per program after clinical proof-of-concept.

The agreement amends the existing OLCA with Gilead, allowing Galapagos to deploy a $500 million cash pool independently for research programs or strategic deals, including up to $150 million for potential share repurchases, dividends or other capital returns, while Gilead leads global commercialization of gamgertamig outside Keymed’s Greater China territories.

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FAQ

How many Lakefront Biotherapeutics NV (GLPGF) SEC filings are available on StockTitan?

StockTitan tracks 39 SEC filings for Lakefront Biotherapeutics NV (GLPGF), including 10-K annual reports, 10-Q quarterly reports, 8-K current reports, and Form 4 insider trading disclosures. Each filing includes AI-generated summaries, impact scoring, and sentiment analysis.

When was the most recent SEC filing for Lakefront Biotherapeutics NV (GLPGF)?

The most recent SEC filing for Lakefront Biotherapeutics NV (GLPGF) was filed on June 24, 2026.