UNITED
STATES
SECURITIES
AND EXCHANGE COMMISSION
WASHINGTON,
D.C. 20549
FORM
6-K
REPORT
OF FOREIGN PRIVATE ISSUER
PURSUANT
TO RULE 13a-16 OR 15d-16 UNDER
THE
SECURITIES EXCHANGE ACT OF 1934
For
the month of April 2026
Commission
File Number: 001-41115
GENENTA
SCIENCE S.P.A.
(Translation
of registrant’s name into English)
Via
dell’Annunciata 31
20121
Milan, Italy
(Address
of Principal Executive Offices)
Indicate
by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F.
Form
20-F ☒ Form 40-F ☐
Indicate
by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(1): ☐
Indicate
by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(7): ☐
This
report on Form 6-K, including Exhibit 10.1, is incorporated by reference into the registrant’s registration statement on Form F-3
(File No. 333-271901).
Other
Events
Sòphia
High Tech Purchase and Investment Agreement
In
addition to its current activities as a clinical-stage biotechnology company focused on the development of Temferon, the Company intends
to expand as a biotech, defense, aerospace, and national security industrial consolidator focused on acquiring majority ownership of
privately held Italian businesses operating in national-security regulated sectors contemplated by the Italian Golden Power legislation.
In
connection with this strategic expansion, on April 22, 2026, the Company entered into a Purchase and Investment Agreement (the “Agreement”)
with Caraviello S.r.l. (“Caraviello”) and Sansone S.r.l. (“Sansone”) ACS Aircraft Solutions S.r.l. (“ACS”)
and Domenico Borrelli (“Borrelli”) together the “Founders” to acquire a majority equity ownership in Sòphia
High Tech S.r.l. (“Sòphia HT”). Sòphia HT is an Italian aerospace and defense engineering and manufacturing
company, headquartered in Somma Vesuviana (Naples), Italy. Sòphia HT manufactures critical parts for Europe’s space and
defense programs.
The
Company expects to fund a total of EUR 6.0 million, which will include a capital increase in two tranches (the second tranche being subject
to certain EBITDA performance milestones) and certain payments to the Founders. The Agreement provides for an initial acquisition by
the Company of 19.9% equity ownership in Sòphia HT in exchange for certain payments to the Founders, as well as a cash subscription
in the form of a capital increase in Sòphia HT’s reserved capital in the aggregate amount of €3.25 million. The Agreement
provides for an opportunity to acquire up to an aggregate of 51% equity ownership in Sòphia HT pursuant to a second tranche involving
another cash subscription, subject to Sòphia HT meeting certain EBITDA performance milestones in the aggregate amount of approximately
€2.25 million. The Agreement also provides for an earnout payment to the Founders, subject to Sòphia HT meeting certain EBITDA
performance milestones of up to €0.5 million. The Company has the unilateral right to exercise its second tranche option regardless
of whether Sòphia HT meets certain EBITDA targets or not. The Agreement is subject to certain closing conditions, including required
government approvals, and certain other conditions that are customary for a proposed transaction of this nature.
The
foregoing description of the Agreement does not purport to be complete and is qualified in its entirety by reference to the full text
of the Agreement, a copy of which is filed as Exhibit 10.1 to this Current Report on Form 6-K (this “Report”) and is incorporated
by reference herein. The full text of the press release issued in connection with the announcement of the Agreement is filed as Exhibit
99.1 to this Report.
Forward-Looking
Statements
This
Report contains forward-looking statements that involve risks and uncertainties, such as statements related to the Company’s acquisition
of equity ownership in Sòphia HT. The risks and uncertainties involved include the Company’s and Sòphia HT’s
ability to satisfy the conditions contained in the Agreement, including but not limited to required government approvals, Sòphia
HT’s ability to satisfy the applicable performance-based criteria, market conditions, and other risks detailed from time to time
in the Company’s periodic reports and other filings with the SEC. You are cautioned not to place undue reliance on forward-looking
statements, which are based on the Company’s current expectations and assumptions and speak only as of the date of this Report.
The Company does not intend to revise or update any forward-looking statement in this Report as a result of new information, future events
or otherwise, except as required by law.
SUBMITTED
HEREWITH
Attached
to this Report for the month of April 2026, and incorporated by reference herein, is:
| Exhibit
No. |
|
Description
|
| 10.1* |
|
Share Purchase and Investment Agreement dated April 22, 2026, between the Company, Caraviello S.r.l., Sansone S.r.l., ACS Aircraft Solutions S.r.l., and Domenico Borrelli. |
| |
|
|
| 99.1 |
|
Press release dated April 23, 2026, titled: “Genenta signs Definitive Agreements with Sophia High Tech.” |
* Certain portions of this exhibit (indicated with “[***]”) have been redacted in accordance with Item 601(b)(10)(iv) of Regulation S-K. Certain annexes, schedules, and exhibits have also been omitted pursuant to Item 601(a)(5) of Regulation S-K.
SIGNATURES
Pursuant
to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by
the undersigned hereunto duly authorized.
| |
GENENTA SCIENCE S.P.A. |
| |
|
|
| |
By: |
/s/ Pierluigi
Paracchi |
| |
Name: |
Pierluigi Paracchi |
| |
Title: |
Chief Executive Officer |
Dated:
April 23, 2026
Exhibit
99.1

Genenta
signs Definitive Agreements with Sophia High Tech
Genenta
enters aerospace as it continues its strategic transformation into a next-generation industrial consolidator
Milan,
Italy – April 23, 2026 - Genenta Science S.p.A. (Nasdaq: GNTA), evolving into Saentra Forge1, a strategic industrial
consolidator focused on biotech, defense, aerospace, and Italian national-security-related technologies, today announced that it has
signed definitive agreements2 with Sòphia High Tech S.r.l., (Sòphia HT) an Italian company manufacturing
critical parts for Europe’s space and defense programs.
Genenta
expects to fund a total of €6.0 million in two tranches. With the closing of the first tranche, Genenta will obtain a 19.9%
stake, and with the closing of the second tranche, Genenta will own a 51% stake in Sòphia HT. The proceeds are expected to be
deployed by Sòphia HT to materially scale production capacity, accelerate technological differentiation, and strengthen commercial
penetration.
Sòphia
HT joins Genenta with a solid net cash position and an already profitable operating profile. In its latest filed financial
statements for fiscal year 2024, Sòphia HT reported3 total revenues and other operating income of approximately €6.29
million and EBITDA of approximately €0.96 million. Based on preliminary internal figures currently under finalization for fiscal
year 2025, Sòphia HT expects sales of approximately €8 million. Over the medium term, Sòphia HT currently expects
to approximately double its 2024 revenue base by 2027, while expanding its workforce from 44 employees currently to approximately 70
by 2027. Genenta expects to add value to Sòphia HT by providing expanded visibility, strong financial controls, and executive
management and leadership. The EBITDA expansion trajectory is structurally underpinned by a multi-year efficiency program targeting
margin growth, driven by the progressive insourcing of high-value processes, increased asset utilization, and a more disciplined
cost structure as scale builds. We believe that this operational leverage would be accelerated by Genenta’s capital injection,
which enables targeted capex for capacity build-out and automation, and enhances access to high-value, institutional-grade demand channels
— compressing execution timelines and de-risking growth.
Sòphia
High Tech is an aerospace and defense engineering and manufacturing company, headquartered in Somma Vesuviana (Naples), Italy. Since
its founding in 2013, Sòphia HT has grown from a specialized engineering boutique into a recognized European aerospace
manufacturer, employing a team of more than 40 engineers, PhD researchers, and skilled technical specialists. Sòphia HT
focuses on the design, simulation, prototyping, manufacturing, testing, and qualification of precision mechanical components and assemblies
for space, defense, and advanced industrial applications. With over 530 advanced projects completed, Sòphia HT serves
leading European aerospace and defense organizations, including the European Space Agency, Italian Aerospace Agency, AVIO, Thales
Alenia Space, Leonardo, MBDA, GSSI, and D-Orbit, and also prestigious automotive brands such as Lamborghini.
This
transaction reflects the broader strategic transformation discussed by our CEO, Pierluigi Paracchi, in a recent episode of Economic
Security Watch, the new podcast from fDi Intelligence, a Financial Times company, where he joined Danielle Myles to
discuss Genenta’s evolution from biotech into a strategic consolidator active across Italy’s national security sectors. The
interview is available here: https://www.fdiintelligence.com/video/70c2aff3-7336-4496-956f-30ff7ae5c582
About
Genenta Science
Genenta
Science (Nasdaq: GNTA) is evolving into a next-generation strategic consolidator focused on privately held specialized companies operating
in Italian national security-regulated sectors, with activities spanning cybersecurity, defense, aerospace, and biotechnology/biosecurity.
1
The name change from Genenta Science S.p.A. to Saentra Forge S.p.A. is subject to shareholder
approval.
2
The transaction will be subject, among other conditions, to the condition precedent relating to obtaining clearance from the Italian
Presidency of the Council of Ministers.
3
The historical and current financial statements of Sophia HT are unaudited.
About
Sòphia High Tech
Sòphia
High Tech S.r.l. is an Italian aerospace and defense engineering and manufacturing company. At its core, Sòphia builds the critical
mechanical components of space and defense systems — the precision parts that hold rockets together, protect satellites in orbit,
and allow aircraft to perform under extreme stress. The company covers the entire product lifecycle, from initial concept design and
computer simulation, through prototyping and manufacturing, all the way to final testing, assembly, and qualification for flight. What
sets Sòphia apart is its mastery of advanced manufacturing techniques — including state-of-the-art metal 3D printing (known
as Selective Laser Melting), CNC precision machining and multitasking, and the ability to work with some of the most demanding exotic
materials in the industry, including titanium, Inconel, tungsten, and specialized copper alloys. The company also conducts original materials
research — developing entirely new metallic blends tailored to the specific demands of space propulsion. Certified to the EN9100
aerospace quality standard and to ECSS-Q-ST-70-80C, the ESA specification for additive manufacturing, Sòphia is one of the very
few companies in Europe qualified to 3D-print flight-ready space hardware to ESA and NASA standards. With over 530 advanced projects
completed, Sòphia serves leading European aerospace and defense organizations, including ESA, AVIO, Thales Alenia Space, Leonardo,
MBDA, GSSI, and D-Orbit.
Non-GAAP
Information. This release includes EBITDA, which is a non-GAAP financial measure. EBITDA is defined as net loss adjusted to exclude
interest income, income tax expense, and depreciation and amortization. This non-GAAP measure is not in accordance with, or an alternative
for, measures prepared in accordance with generally accepted accounting principles (GAAP) and may be different from non-GAAP measures
used by other companies. In addition, this non-GAAP measure is not based on any comprehensive set of accounting rules or principles.
Genenta believes that this non-GAAP financial measure, when considered together with financial information prepared in accordance with
GAAP, can enhance investors’ and analysts’ ability to meaningfully compare financial results from period to period and to
forward-looking guidance, and to identify operating trends in the business. However, non-GAAP information is not superior to financial
measures calculated in accordance with GAAP, is presented for supplemental informational purposes only, has limitations as an analytical
tool, and should not be considered in isolation or as a substitute for financial information presented in accordance with GAAP.
Forward-Looking
Statements. Statements in this press release contain “forward-looking statements,” within the meaning of the U.S. Private
Securities Litigation Reform Act of 1995, that are subject to substantial risks and uncertainties. All statements, other than statements
of historical fact, contained in this press release are forward-looking statements. Forward-looking statements contained in this press
release may be identified by the use of words such as “anticipate,” “believe,” “contemplate,” “could,”
“estimate,” “expect,” “intend,” “seek,” “may,” “might,” “plan,”
“potential,” “predict,” “project,” “suggest,” “target,” “aim,”
“should,” “will,” “would,” or the negative of these words or other similar expressions, although
not all forward-looking statements contain these words. Forward-looking statements are based on Genenta’s current expectations
and are subject to inherent uncertainties, risks, and assumptions that are difficult to predict, including risks related to the transition
to Saentra Forge, ability to close the transaction with Sòphia High Tech, financial forecasts of Sòphia High Tech, and
expected use of proceeds of Sòphia High Tech, etc.. Further, certain forward-looking statements are based on assumptions as to
future events that may not prove to be accurate. These and other risks and uncertainties are described more fully in the section titled
“Risk Factors” in Genenta’s Annual Report on Form 20-F for the year ended December 31, 2024, and Genenta’s material
disclosures on Form 6-K dated October 10, 2025, as well as other Form 6-K disclosures filed with the Securities and Exchange Commission.
Forward-looking statements contained in this announcement are made as of the date of this announcement, and Genenta undertakes no duty
to update such information except as required under applicable law.
Genenta
Science Media
Tiziana
Pollio, Mobile: +39 348 23 15 143
email:
tiziana.pollio@genenta.com