UNITED
STATES
SECURITIES
AND EXCHANGE COMMISSION
WASHINGTON,
D.C. 20549
FORM
6-K
REPORT
OF FOREIGN PRIVATE ISSUER
PURSUANT
TO RULE 13a-16 OR 15d-16 UNDER
THE
SECURITIES EXCHANGE ACT OF 1934
For
the month of March 2026
Commission
File Number: 001-41115
GENENTA
SCIENCE S.P.A.
(Translation
of registrant’s name into English)
Via
dell’Annunciata 31
20121
Milan, Italy
(Address
of Principal Executive Offices)
Indicate
by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F.
Form
20-F ☒ Form 40-F ☐
Indicate
by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(1): ☐
Indicate
by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(7): ☐
This
report on Form 6-K, including Exhibit 10.1, is incorporated by reference into the registrant’s registration statement on Form F-3
(File No. 333-271901).
Other
Events
Sòphia
High Tech Binding Offer
In
addition to its current activities as a clinical-stage biotechnology company focused on the development of Temferon, the Company intends
to expand as a biotech, defense, aerospace, and national security industrial consolidator focused on acquiring majority ownership of
privately held Italian businesses operating in national-security regulated sectors contemplated by the Italian Golden Power legislation.
In
connection with this strategic expansion, on March 25, 2026, the Company entered into a Binding Offer (the “Offer”) with
Caraviello S.r.l. (“Caraviello”) and Sansone S.r.l. (“Sansone” and together with Caraviello, the “Founders”)
to acquire a majority equity ownership in Sòphia High Tech S.r.l. (“Sòphia HT”). Sòphia HT is an Italian
aerospace and defense engineering and manufacturing company, headquartered in Somma Vesuviana (Naples), Italy. It manufactures critical
parts for Europe’s space and defense programs.
The Offer provides for an initial acquisition
by the Company of 30% equity ownership in Sòphia HT in exchange for certain payments to the Founders, as well as
a cash subscription in the form of a capital increase in Sòphia HT’s reserved capital. The Offer provides for an opportunity
to acquire up to an aggregate of 51% equity ownership in Sòphia HT pursuant to a second tranche involving another cash
subscription, subject to Sòphia HT meeting certain EBITDA performance milestones. The Offer also provides for an earnout payment
to the Founders, subject to Sòphia HT meeting certain EBITDA performance milestones. The Company expects to fund a total of EUR
6.0 million, which will include a capital increase in two tranches (the second tranche being subject to EBITDA performance milestones)
and certain payments to the Founders (with the second tranche being an earnout payment subject to EBITDA performance milestones).
The Offer contains a 90-day exclusivity period, and if the parties have not executed transaction documentation by the end of that period,
the Offer will automatically cease to be effective. The proposed transaction is subject to the Company’s confirmatory due diligence,
required government approvals, and certain other conditions that are customary for a proposed transaction of this nature.
The
foregoing description of the Offer does not purport to be complete and is qualified in its entirety by reference to the full text of
the Offer, a copy of which is filed as Exhibit 10.1 to this Current Report on Form 6-K (this “Report”) and is incorporated
by reference herein. The full text of the press release issued in connection with the announcement of the Offer is filed as Exhibit 99.1
to this Report.
Forward-Looking
Statements
This
Report contains forward-looking statements that involve risks and uncertainties, such as statements related to the Company’s anticipated
acquisition of equity ownership in Sòphia HT. The risks and uncertainties involved include the Company’s ability to satisfy
the conditions contained in the Offer, including but not limited to, confirmatory due diligence, required government approvals, and definitive
transaction documentation, Sòphia HT’s ability to satisfy the applicable performance-based criteria, market conditions,
and other risks detailed from time to time in the Company’s periodic reports and other filings with the SEC. You are cautioned
not to place undue reliance on forward-looking statements, which are based on the Company’s current expectations and assumptions
and speak only as of the date of this Report. The Company does not intend to revise or update any forward-looking statement in this Report
as a result of new information, future events or otherwise, except as required by law.
SUBMITTED
HEREWITH
Attached
to this Report for the month of March 2026, and incorporated by reference herein, is:
| Exhibit
No. |
|
Description
|
| 10.1* |
|
Binding Offer dated March 25, 2026, between the Company, Caraviello S.r.l. and Sansone S.r.l. |
| |
|
|
| 99.1
|
|
Press release dated March 27, 2026, titled: “Genenta, Evolving into Saentra Forge, has signed a Binding Offer with Sòphia High Tech, an Italian Company Manufacturing Critical Parts for Europe’s Space and Defense Programs.” |
* Certain portions of this exhibit (indicated
with “[***]”) have been redacted in accordance with Item 601(b)(10)(iv).
SIGNATURES
Pursuant
to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by
the undersigned hereunto duly authorized.
| |
GENENTA
SCIENCE S.P.A. |
| |
|
|
| |
By: |
/s/
Pierluigi Paracchi |
| |
Name:
|
Pierluigi
Paracchi |
| |
Title: |
Chief
Executive Officer |
Dated:
March 27, 2026
Exhibit
99.1

Genenta,
evolving into Saentra Forge, has signed a Binding Offer with Sòphia High Tech, an Italian company manufacturing critical parts
for Europe’s space and defense programs
Milan,
Italy – March 27, 2026 - Genenta Science S.p.A. (Nasdaq: GNTA), evolving into Saentra Forge1, a strategic industrial
consolidator focused on biotech, defense, aerospace, and Italian national-security-related technologies, today announced that it has
entered into a binding offer with Sòphia High Tech S.r.l., (Sòphia HT) an Italian company manufacturing
critical parts for Europe’s space and defense programs, under which Genenta will fund Sòphia through two reserved capital
increases, with the goal of reaching a controlling stake upon the achievement of defined performance milestones. The transaction with
Sòphia High Tech would be completed in two phases and remains subject to confirmatory due diligence, required approvals, and definitive
transaction documentation.
Sòphia
High Tech is an aerospace and defense engineering and manufacturing company, headquartered in Somma Vesuviana (Naples), Italy. Since
its founding in 2013, Sòphia High Tech has grown from a specialized engineering boutique into a recognized European aerospace
manufacturer, employing a team of more than 40 engineers, PhD researchers, and skilled technical specialists. Sòphia HT
focuses on the design, simulation, prototyping, manufacturing, testing, and qualification of precision mechanical components and assemblies
for space, defense, and advanced industrial applications. With over 530 advanced projects completed, Sòphia serves
leading European aerospace and defense organizations, including the European Space Agency, Italian Aerospace Agency, AVIO, Thales
Alenia Space, Leonardo, MBDA, GSSI, and D-Orbit, and also prestigious automotive brands such as Lamborghini.
Genenta
expects to fund a total of EUR 6.0 million in two tranches, the second tranche being performance-driven. Sòphia High Tech
is projecting growing revenues and operates with a solid net cash position, reflecting a disciplined management structure.
Sòphia HT is already profitable and forecasts continued EBITDA growth in 2026, 2027 and beyond2. The funds are
expected to be used for materially scaling production capacity, accelerating technological differentiation, and strengthening commercial
penetration3.
“Our
decision to pursue the acquisition of Sòphia High Tech was not driven simply by the fact that it is a great company — though
it is. We are proposing to acquire it because it represents exactly the kind of irreplaceable industrial asset that Italy cannot afford
to lose.” said Pierluigi Paracchi, CEO of Genenta. “With a thriving small satellite industry, a national space agency
investing heavily through NRRP[4] funds, and aerospace primes such as MBDA and AVIO anchoring a world-class
supply chain, there is growing international attention on Italian deep-tech companies capable of delivering at the highest levels
of complexity and reliability. Sòphia HT is perfectly positioned for this moment - a highly specialized, nimble, and deeply technical
company with proven flight heritage, growing revenue, and proprietary manufacturing know-how that cannot be replicated. But this proposed
acquisition is about more than one company. It is about a model. Sòphia HT is our legacy. The people behind it — the engineers,
the PhDs, the machinists who build components that fly in space — they are our patrimony. Keeping them here, growing here, winning
from here — that is the mission. That is what strategic acquisition means to us.”
“A
strong synergy was immediately established with Genenta. Through investments focused on Facilities, Certifications, and People, it will
ensure, in addition to an increase in Sòphia’s manufacturing activities, an ever-increasing involvement with our customers.”
said Antonio Caraviello, CEO of Sòphia High Tech.
1
The name change from Genenta Science S.p.A. to Saentra Forge S.p.A. is subject to shareholder approval.
2
See “Non-GAAP Information” below for a discussion of the measure EBITDA
3
For additional information, please refer to our Form 6-K, which will be filed with the Securities and Exchange Commission today.
4
National Recovery and Resilience Plan (NRRP)

About
Genenta Science
Genenta
Science (Nasdaq: GNTA), is evolving into a next-generation strategic consolidator focused on privately held specialized companies operating
in Italian national security-regulated sectors, with activities spanning cybersecurity, defense, aerospace, and biotechnology/biosecurity.
About
Sòphia High Tech
Sòphia
High Tech S.r.l. is an Italian aerospace and defense engineering and manufacturing company. At its core, Sòphia builds the critical
mechanical components of space and defense systems — the precision parts that hold rockets together, protect satellites in orbit,
and allow aircraft to perform under extreme stress. The company covers the entire product lifecycle, from initial concept design and
computer simulation, through prototyping and manufacturing, all the way to final testing, assembly, and qualification for flight. What
sets Sòphia apart is its mastery of advanced manufacturing techniques — including state-of-the-art metal 3D printing (known
as Selective Laser Melting), CNC precision machining and multitasking, and the ability to work with some of the most demanding exotic
materials in the industry, including titanium, Inconel, tungsten, and specialized copper alloys. The company also conducts original materials
research — developing entirely new metallic blends tailored to the specific demands of space propulsion. Certified to the EN9100
aerospace quality standard and to ECSS-Q-ST-70-80C, the ESA specification for additive manufacturing, Sòphia is one of the very
few companies in Europe qualified to 3D-print flight-ready space hardware to ESA and NASA standards. With over 530 advanced projects
completed, Sòphia serves leading European aerospace and defense organizations including ESA, AVIO, Thales Alenia Space, Leonardo,
MBDA, GSSI, and D-Orbit.
Non-GAAP
Information. This release includes EBITDA, which is a non-GAAP financial measure. EBITDA is defined as net loss adjusted to exclude
interest income, income tax expense, and depreciation and amortization. This non-GAAP measure is not in accordance with, or an alternative
for, measures prepared in accordance with generally accepted accounting principles (GAAP) and may be different from non-GAAP measures
used by other companies. In addition, this non-GAAP measure is not based on any comprehensive set of accounting rules or principles.
Genenta believes that this non-GAAP financial measure, when considered together with financial information prepared in accordance with
GAAP, can enhance investors’ and analysts’ ability to meaningfully compare its results from period to period and to forward-looking
guidance, and to identify operating trends in its business. However, non-GAAP information is not superior to financial measures calculated
in accordance with GAAP, is presented for supplemental informational purposes only, has limitations as an analytical tool, and should
not be considered in isolation or as a substitute for financial information presented in accordance with GAAP.
Forward-Looking
Statements. Statements in this press release contain “forward-looking statements,” within the meaning of the U.S. Private
Securities Litigation Reform Act of 1995, that are subject to substantial risks and uncertainties. All statements, other than statements
of historical fact, contained in this press release are forward-looking statements. Forward-looking statements contained in this press
release may be identified by the use of words such as “anticipate,” “believe,” “contemplate,” “could,”
“estimate,” “expect,” “intend,” “seek,” “may,” “might,” “plan,”
“potential,” “predict,” “project,” “suggest,” “target,” “aim,”
“should,” “will,” “would,” or the negative of these words or other similar expressions, although
not all forward-looking statements contain these words. Forward-looking statements are based on Genenta’s current expectations
and are subject to inherent uncertainties, risks, and assumptions that are difficult to predict, including risks related to the transition
to Saentra Forge, the expansion to a sovereign-aligned industrial consolidator, the legal proceedings with ENEA Tech, the funding provided
by the recently acquired Mandatory Convertible Bond, etc. Further, certain forward-looking statements are based on assumptions as to
future events that may not prove to be accurate. These and other risks and uncertainties are described more fully in the section titled
“Risk Factors” in Genenta’s Annual Report on Form 20-F for the year ended December 31, 2024, and Genenta’s material
disclosures on Form 6-K dated October 10, 2025, as well as other Form 6-K disclosures filed with the Securities and Exchange Commission.
Forward-looking statements contained in this announcement are made as of the date of this announcement, and Genenta undertakes no duty
to update such information except as required under applicable law.
Genenta
Science Media
Tiziana
Pollio, Mobile: +39 348 23 15 143
email:
tiziana.pollio@genenta.com