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RA Capital adjusts Werewolf Therapeutics (HOWL) stake to 10.6% ownership

Filing Impact
(Moderate)
Filing Sentiment
(Neutral)
Form Type
SCHEDULE 13D/A

Rhea-AI Filing Summary

RA Capital Management and affiliates report owning 5,138,703 shares of Werewolf Therapeutics common stock, representing 10.6% of the company. Most of these shares, 4,797,350 or 9.9% of the class, are held by RA Capital Healthcare Fund, with additional shares held by RA Capital Nexus Fund II.

The filing details that RA Capital has shared power to vote and dispose of these shares, while the underlying funds have delegated voting and investment authority and disclaim beneficial ownership for certain legal purposes. The amendment notes that the reported ownership percentage reflects an increase in Werewolf’s outstanding shares and lists recent open market sales by the Fund and Nexus Fund II in June 2026.

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Insights

RA Capital discloses a 10.6% stake in Werewolf with recent sales.

RA Capital Management, its healthcare fund, and related entities report beneficial ownership of 5,138,703 Werewolf Therapeutics shares, or 10.6% of the common stock based on 48,596,817 shares outstanding as of May 1, 2026.

The healthcare fund directly holds 4,797,350 shares, or 9.9% of the class, while RA Capital Nexus Fund II holds additional shares. Voting and dispositive power are centralized at RA Capital, with the funds delegating authority and formally disclaiming certain beneficial ownership for Section 13(d) purposes.

The filing also lists several June 2026 open market sales by the Fund and Nexus Fund II at per-share prices around $0.37–$0.40. The amendment states that the updated percentage mainly reflects a higher number of outstanding issuer shares, so the change is largely structural rather than driven solely by trading.

Beneficial ownership 5,138,703 shares Shares of Werewolf Therapeutics common stock beneficially owned by each reporting person
Ownership percentage 10.6% Percent of Werewolf common stock class represented by 5,138,703 shares
Fund holdings 4,797,350 shares Shares held directly by RA Capital Healthcare Fund, L.P.; 9.9% of class
Class percentage (Fund) 9.9% Percent of Werewolf common stock class held by RA Capital Healthcare Fund, L.P.
Shares outstanding 48,596,817 shares Common stock outstanding as of May 1, 2026, per issuer’s Form 10-Q
Sample open market sale 345,235 shares at $0.37 Open market sale by Fund on June 9, 2026; low $0.36, high $0.3791
Sample open market sale price $0.40 per share Weighted average price for Fund sale on June 12, 2026; low $0.3814, high $0.4129
beneficial owner financial
"may be deemed a beneficial owner, for purposes of Section 13(d) of the Securities Exchange Act of 1934"
A beneficial owner is the person who ultimately owns or controls a financial asset or property, even if their name isn't directly on official documents. Think of it like someone who secretly holds the keys to a safe deposit box—others may appear to have access, but the true owner is the one who benefits from what's inside. Identifying beneficial owners helps ensure transparency and prevent illegal activities like money laundering or fraud.
shared Voting Power financial
"Number of Shares Beneficially Owned by Each Reporting Person With: | 7 | Sole Voting Power 0.00 8 | Shared Voting Power 5,138,703.00"
Shared voting power occurs when two or more parties jointly have the right to vote or decide how a block of company shares is cast, like co-owners who must agree before moving a piece of furniture. Investors care because who controls voting rights affects board elections, major corporate decisions and takeover outcomes, and shared control can alter regulatory disclosures and the practical influence any holder has over a company’s direction and value.
shared Dispositive Power financial
"10 | Shared Dispositive Power 5,138,703.00"
open market sale financial
"Weighted Low High No. Average Price Price Transaction Seller Date Shares Price ($) ($) ($) Open Market Sale Fund 06/09/2026"
An open market sale is when a company or a shareholder sells shares through the regular stock market to any willing buyer, using ordinary exchange trading rather than private deals. It matters to investors because it increases the number of shares available and can push the price down or change ownership balance—think of it like someone putting extra items on a supermarket shelf for any shopper to buy, which can lower the item's price if supply suddenly grows.
Schedule 13D/A financial
"This Amendment No. 9 (this "Amendment No. 9" or this "/A") amends and supplements the statement on originally filed"
A Schedule 13D/A is an amended disclosure filed with regulators by an investor who already reported owning more than 5% of a company’s shares and needs to update their original filing. Think of it as a public status update that tells markets whether the investor’s ownership, plans, or source of funds have changed; such updates matter because they can signal a push for control, major strategic moves, or increased pressure on management, which can affect stock prices.
joint filing agreement financial
"The agreement among the Reporting Persons to file this Schedule 3D/A jointly in accordance with Rule 13d-1(k)"
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FAQ

What percentage of Werewolf Therapeutics (HOWL) does RA Capital now report owning?

RA Capital and related reporting persons disclose beneficial ownership of 5,138,703 shares of Werewolf Therapeutics common stock, representing 10.6% of the outstanding shares. This percentage is based on 48,596,817 shares outstanding as of May 1, 2026.

How many Werewolf Therapeutics shares are held by RA Capital Healthcare Fund?

RA Capital Healthcare Fund directly holds 4,797,350 shares of Werewolf Therapeutics common stock. This position represents 9.9% of the class, calculated using 48,596,817 shares outstanding as of May 1, 2026, as disclosed in the company’s Form 10-Q.

Did RA Capital recently trade Werewolf Therapeutics (HOWL) shares?

Yes. The amendment lists several open market sales by RA Capital Healthcare Fund and RA Capital Nexus Fund II between June 9 and June 15, 2026. Trade sizes range from thousands to hundreds of thousands of shares at prices around $0.36–$0.41 per share.

What is the total share count used to calculate RA Capital’s 10.6% stake in HOWL?

The reported 10.6% ownership is calculated using 48,596,817 shares of common stock outstanding as of May 1, 2026. This outstanding share figure comes from Werewolf Therapeutics’ Form 10-Q filed with the SEC on May 7, 2026.

Who has voting and investment power over RA Capital’s Werewolf Therapeutics shares?

RA Capital Management, L.P. serves as investment adviser to the RA Capital Healthcare Fund and RA Capital Nexus Fund II. The funds have delegated sole voting and dispositive power to RA Capital, which may be deemed a beneficial owner under Section 13(d) for these securities.

Why do RA Capital and the funds disclaim certain beneficial ownership of HOWL shares?

The funds have delegated voting and investment authority over their Werewolf shares to RA Capital and cannot revoke this delegation on less than 61 days’ notice. As a result, the funds disclaim beneficial ownership for Section 13(d) purposes, while RA Capital and its managers also include legal disclaimers.





95075A107

(CUSIP Number)
Peter Kolchinsky
RA Capital Management, L.P., 200 Berkeley Street, 18th Floor
Boston, MA, 02116
617.778.2500

(Name, Address and Telephone Number of Person Authorized to Receive Notices and Communications)
06/11/2026

(Date of Event Which Requires Filing of This Statement)


If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of §§ 240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the following box.

The information required on the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).




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SCHEDULE 13D






SCHEDULE 13D






SCHEDULE 13D






SCHEDULE 13D






SCHEDULE 13D


RA Capital Management, L.P.
Signature:/s/ Peter Kolchinsky
Name/Title:By Peter Kolchinsky, Authorized Signatory
Date:06/15/2026
Peter Kolchinsky
Signature:/s/ Peter Kolchinsky
Name/Title:Peter Kolchinsky
Date:06/15/2026
Rajeev Shah
Signature:/s/ Rajeev Shah
Name/Title:Rajeev Shah
Date:06/15/2026
RA Capital Healthcare Fund, L.P.
Signature:/s/ Peter Kolchinsky
Name/Title:By RA Capital Healthcare Fund GP, LLC, its General Partner, By Peter Kolchinsky, Manager
Date:06/15/2026