Humacyte, Inc. filings document a commercial-stage biotechnology issuer built around acellular tissue engineered vessels and related bioengineered human tissue programs. Its reports and 8-K filings cover operating results, product commercialization, clinical and regulatory disclosures, material agreements for Symvess distribution rights, and collaboration or licensing arrangements.
The company’s SEC record also includes capital-structure disclosures for common stock and redeemable warrants, equity offering arrangements, secured debt financing, and Nasdaq listing-rule notices. Proxy materials describe board matters, executive compensation, equity awards, shareholder voting items and other governance disclosures for HUMA.
Humacyte, Inc. filed a preliminary prospectus supplement to offer shares of common stock (number and price not specified in the excerpt) and granted underwriters a 30-day option to purchase additional shares. Net proceeds are intended to fund Symvess commercialization, a planned supplemental BLA filing for hemodialysis, pipeline development and working capital.
The supplement also discloses positive top-line interim results from the V012 Phase 3 trial: ATEV patients averaged 220 catheter-free days versus 129 for AV fistula (p=0.00070), with infection rates of 6 vs. 23 per 100 patient-years. The company plans a supplemental BLA submission in the second half of 2026. Management reports available cash and equity capacity that fund operations into the first quarter of 2027 but states there is substantial doubt about its ability to continue as a going concern without additional financing.
Humacyte, Inc. reported positive interim Phase 3 results for its acellular tissue engineered vessel (ATEV) in female dialysis patients. In the V012 study’s prespecified analysis of the first 80 patients, ATEV met the primary endpoint, delivering an average of 91 more catheter-free days than autologous arteriovenous fistula, the current standard of care.
ATEV patients achieved 220 catheter-free days versus 129 with fistula (p=0.00070) and showed substantially lower infection rates. Based on these results, enrollment will stop and follow-up will continue, and Humacyte plans to file a supplemental Biologic License Application with the FDA in the second half of 2026 for high-risk end-stage kidney disease patients.
Humacyte, Inc. reported results of its 2026 Annual Meeting of Stockholders held on June 9, 2026. Stockholders approved an amendment to the Certificate of Incorporation increasing authorized common shares from 350,000,000 to 550,000,000, which became effective upon filing in Delaware on June 9, 2026.
As of the April 23, 2026 record date, 222,019,108 common shares were outstanding, and 127,474,086 shares, or about 57.41%, were represented to form a quorum. Stockholders elected three Class II directors, approved on an advisory basis the compensation of named executive officers and chose to hold future say-on-pay votes annually.
They also ratified the appointment of PricewaterhouseCoopers LLP as independent registered public accounting firm for the fiscal year ending December 31, 2026 and formally approved the increase in authorized common stock. No broker non-votes were recorded on the auditor ratification or share authorization proposals.
Humacyte, Inc. has regained compliance with Nasdaq’s minimum bid price rule. The company had previously been notified that its common stock traded below the required $1.00 per share bid price for 30 consecutive business days ended May 1, 2026.
To cure the issue, Humacyte’s stock needed to close at or above $1.00 for at least 10 consecutive business days before November 2, 2026. On June 5, 2026, Nasdaq informed the company that this condition was met and that its listing on The Nasdaq Global Select Market is now in good standing, with the matter considered closed.
Humacyte, Inc. director Kathleen Sebelius reported an open-market purchase of 56,818 shares of Humacyte common stock at a price of $0.88 per share on May 19, 2026. Following this transaction, she directly holds a total of 148,025 Humacyte common shares.
Humacyte, Inc. director Michael T. Constantino reported an open-market purchase of common stock. On May 18, 2026, he bought 11,000 shares of Humacyte common stock at a weighted average price of $0.8945 per share in multiple transactions.
Following this purchase, Constantino directly owns 43,950 common shares. The filing notes that the trades were executed across a price range from $0.8922 to $0.8958 per share and that detailed trade-by-trade pricing is available upon request.
Humacyte, Inc. CFO and Chief Corporate Development Officer Dale A. Sander reported an automated sale of 45,887 shares of common stock at an average price of $0.8967 per share. The sale was executed solely to cover statutory tax withholding from vested restricted stock units under a pre-arranged Rule 10b5-1 sell-to-cover plan, not as a discretionary sale. After this transaction, he holds 267,213 shares directly and 40,600 shares indirectly through his spouse.
Humacyte, Inc.'s Chief Medical Officer, Shamik J. Parikh, reported an automated sale of 45,887 shares of common stock at an average price of $0.8967 per share.
The filing explains this was a mandatory “sell-to-cover” transaction to fund statutory tax withholding tied to vesting of restricted stock units, carried out under a Rule 10b5-1(c) trading plan and not a discretionary sale. After this tax-related sale, Parikh directly holds 272,713 shares of Humacyte common stock.