Hyperion DeFi (HYPD) swings to Q1 2026 profit and raises DeFi earnings guidance

Filing Impact

(Moderate)

Filing Sentiment

(Neutral)

Form Type

8-K

Rhea-AI Filing Summary

Hyperion DeFi, Inc. reported a strong turnaround for the quarter ended March 31, 2026, moving to GAAP net income of $8.84 million from a net loss of $3.48 million a year earlier. Revenue rose to $244,271 from $14,720, reflecting early scaling of its DeFi operating businesses.

Non-GAAP Adjusted EBITDA reached $19.49 million in Q1 2026, compared with a loss of $38.92 million in Q4 2025. Non-GAAP Adjusted Gross Profit grew 17% quarter-over-quarter to $959,568. The company raised full-year 2026 Adjusted Gross Profit guidance to $5–$7 million, roughly five times 2025 levels.

Hyperion’s HYPE token treasury remained substantial, with Gross HYPE Holdings of $71.04 million and Net Asset Value of $69.87 million as of March 31, 2026. The balance sheet showed total assets of $70.07 million and stockholders’ equity of $58.49 million. The company also issued 132,249 additional shares under an underwriter option, generating approximately $0.4 million in net proceeds.

Positive

Strong profitability turnaround: Q1 2026 GAAP net income of $8.84 million versus a $3.48 million loss a year earlier, alongside Adjusted EBITDA of $19.49 million after a large non-GAAP loss in Q4 2025.
Raised 2026 outlook: Full-year 2026 Adjusted Gross Profit guidance increased to $5–$7 million, described as roughly five times 2025 levels, signaling higher expected operating contribution from DeFi activities.

Negative

None.

Insights

Hyperion DeFi swung to profit, expanded token-backed NAV, and raised 2026 guidance.

Hyperion DeFi delivered GAAP net income of $8.84 million for Q1 2026 versus a prior-year loss, on modest GAAP revenue of $244,271. The result is heavily driven by gains on digital assets, but also by growing DeFi operating income.

Non-GAAP metrics highlight this mix: Adjusted EBITDA improved from a loss of $38.92 million in Q4 2025 to $19.49 million in Q1 2026, while Adjusted Gross Profit rose 17% quarter-over-quarter to $959,568. Management now targets full-year 2026 Adjusted Gross Profit of $5–$7 million, several times 2025 levels.

The balance sheet is dominated by digital assets, with Gross HYPE Holdings of $71.04 million and Net Asset Value of $69.87 million as of March 31, 2026. Cash was $7.38 million, and stockholders’ equity $58.49 million. A small share issuance under an underwriter option added about $0.4 million of cash, a minor dilution but incremental liquidity.

8-K Event Classification

4 items: 2.02, 7.01, 8.01, 9.01

4 items

Item 2.02 Results of Operations and Financial Condition Financial

Disclosure of earnings results, typically an earnings press release or preliminary financials.

Item 7.01 Regulation FD Disclosure Disclosure

Material non-public information disclosed under Regulation Fair Disclosure, often investor presentations or guidance.

Item 8.01 Other Events Other

Voluntary disclosure of events the company deems important to shareholders but not covered by other items.

Item 9.01 Financial Statements and Exhibits Exhibits

Financial statements, pro forma financial information, and exhibit attachments filed with this report.

Key Figures

Q1 2026 Revenue: $244,271 Q1 2026 GAAP Net Income: $8,840,550 Q1 2025 GAAP Net Loss: $3,483,533 +6 more

9 metrics

Q1 2026 Revenue $244,271 For the three months ended March 31, 2026

Q1 2026 GAAP Net Income $8,840,550 For the three months ended March 31, 2026

Q1 2025 GAAP Net Loss $3,483,533 For the three months ended March 31, 2025

Q1 2026 Adjusted EBITDA $19,488,132 Non-GAAP metric for the quarter ended March 31, 2026

Q1 2026 Adjusted Gross Profit $959,568 Non-GAAP, up 17% from $820,997 in Q4 2025

2026 Adjusted Gross Profit Guidance $5M–$7M Full-year 2026 guidance, ~5x 2025 levels

Gross HYPE Holdings $71,037,227 As of March 31, 2026

Net Asset Value $69,873,504 As of March 31, 2026

Equity Raise via Underwriter Option $0.4 million Net proceeds from 132,249 shares issued May 13, 2026

Key Terms

Adjusted EBITDA, Adjusted Gross Profit, Net Asset Value, digital intangible assets, +2 more

6 terms

Adjusted EBITDA financial

"Non-GAAP | Adjusted EBITDA (8) | 7,951,003 | ... | 19,488,132"

Adjusted EBITDA is a way companies measure how much money they make from their core operations, like running a business, by removing certain costs or income that aren’t part of regular business activities. It helps investors see how well a company is doing without distractions from unusual expenses or gains, making it easier to compare companies or track performance over time.

Adjusted Gross Profit financial

"Adjusted Gross Profit (1) in total, Adjusted Gross Profit(1) increased +17% quarter-over-quarter"

Adjusted gross profit is a company’s revenue from selling goods or services minus the direct costs of producing them, with one-time or unusual items added back or removed to show the core margin. Investors use it like a cleaned-up snapshot of how much a business actually earns on its products, similar to measuring body weight after removing heavy clothes, because it helps compare performance across periods and companies without noise from rare events.

Net Asset Value financial

"Non-GAAP | Net Asset Value (9) | 74,545,583 | ... | 69,873,504"

Net asset value is the total value of an investment fund's assets minus any liabilities, divided by the number of shares or units outstanding. It represents the per-share worth of the fund, similar to how the value of a house is determined by its total worth after debts are subtracted. Investors use it to gauge the true value of their holdings and to compare different investment options.

digital intangible assets financial

"Digital intangible assets | 16,033,758 | ... | 20,591,555"

Treasury Gains (Losses) financial

"Non-GAAP | Treasury Gains (Losses) (6) | 11,868,872 | ... | 21,451,862"

Treasury gains (losses) are the profits or losses a company records from managing its cash, short-term investments and interest-rate or currency hedges—think of it like the small wins or losses from how a household manages its savings and foreign cash when interest rates or exchange rates change. They matter to investors because they alter reported earnings and cash flow but usually reflect financial management rather than core business performance, so analysts separate them when judging underlying company health.

DeFi Monetization financial

"DeFi Monetization | *The portion of Adjusted Gross Profit(1) earned in cash, cash equivalents, and USDH(16)"

Earnings Snapshot

Revenue: $244,271 · Guidance included

Q1 2026

Revenue $244,271

GAAP Net Income $8,840,550

Adjusted EBITDA $19,488,132

Adjusted Gross Profit $959,568 +17% QoQ

Guidance

Full-year 2026 Adjusted Gross Profit guidance raised to a range of $5 million to $7 million, described as roughly five times 2025 levels.

Understanding 8-K Material Events →

05/14/2026 - 07:00 AM

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 8-K

CURRENT REPORT

Pursuant to Section 13 or 15(d)

of the Securities Exchange Act of 1934

Date of Report (Date of earliest event reported): May 14, 2026

HYPERION DEFI, INC.

(Exact Name of Registrant as Specified in its Charter)

Delaware		001-38365		47-1178401
(State or other jurisdiction of incorporation)		(Commission File Number)		(IRS Employer Identification No.)

3090 Nowitzki Way

Suite 300

Dallas, TX 75219

(Address of Principal Executive Offices, and Zip Code)

(833) 393-6684

Registrant’s Telephone Number, Including Area Code

23461 South Pointe Drive, Suite 390

Laguna Hills, CA 92653

(Former name or former address, if changed since last report)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

¨ Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

¨ Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

¨ Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

¨ Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:

(Title of each class)		(Trading Symbol)		(Name of each exchange on which registered)
Common stock, par value $0.0001 per share		HYPD		The Nasdaq Stock Market (Nasdaq Capital Market)

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (17 CFR §230.405) or Rule 12b-2 of the Securities Exchange Act of 1934 (17 CFR §240.12b-2).

Emerging growth company ¨

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ¨

Item 2.02. Results of Operations and Financial Condition.

On May 14, 2026, Hyperion DeFi, Inc. (the “Company”) issued a press release announcing its financial results for the fiscal quarter ended March 31, 2026. A copy of the press release is furnished as Exhibit 99.1 to this Current Report on Form 8-K and is incorporated herein by reference.

The information contained in this Item 2.02, including Exhibit 99.1, is being “furnished” and shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), or otherwise subject to the liability of that Section or Sections 11 and 12(a)(2) of the Securities Act of 1933, as amended (the “Securities Act”). The information contained in this Item 2.02, including Exhibit 99.1, shall not be incorporated by reference into any registration statement or other document pursuant to the Securities Act or into any filing or other document pursuant to the Exchange Act, except as otherwise expressly stated in any such filing.

Item 7.01. Regulation FD Disclosure.

On May 14, 2026, the Company will host a conference call to discuss its financial and operating results for the quarter ended March 31, 2026. A copy of the investor presentation that will be used during this conference call is furnished as Exhibit 99.2 to this Current Report on Form 8-K and is incorporated herein by reference.

The information contained in this Item 7.01, including Exhibit 99.2, is being “furnished” and shall not be deemed “filed” for purposes of Section 18 of the Exchange Act or otherwise subject to the liability of that Section or Sections 11 and 12(a)(2) of the Securities Act. The information contained in this Item 7.01, including Exhibit 99.2, shall not be incorporated by reference into any registration statement or other document pursuant to the Securities Act or into any filing or other document pursuant to the Exchange Act, except as otherwise expressly stated in any such filing.

Item 8.01 Other Events

On May 13, 2026, pursuant to the Company’s grant to Chardan Capital Markets, LLC (“Chardan”) of a 30-day option to purchase up to 416,666 additional shares under the previously announced Underwriting Agreement dated May 5, 2026 (the “Underwriting Agreement”), the Company issued, and Chardan purchased, 132,249 shares of the Company’s common stock, resulting in approximately $0.4 million in net proceeds to the Company.

Item 9.01. Financial Statements and Exhibits.

(d) Exhibits

Exhibit Number	Description

99.1	Press Release, dated May 14, 2026.
99.2	Investor Presentation, dated May 14, 2026
104	Cover Page Interactive Data File (embedded within the inline XBRL document).

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

	HYPERION DEFI, INC.

Dated: May 14, 2026	By:	/s/ Hyunsu Jung
		Hyunsu Jung
		Chief Executive Officer

Exhibit 99.1

Hyperion DeFi Reports 1Q 2026 Financial Results with Record Net Income and Raises Guidance for Full Year 2026

Company Reports Record $8.8M Net Income and $19.5M Adjusted EBITDA⁽⁸⁾

Treasury Exceeds 2.00M HYPE, 1.92M KNTQ, & 10.00M HPL Tokens as of May 11⁽¹⁴⁾

HYPD’s Unique “Triple-Dip” HYPE Deployment Generated >3x Base Staking Income in Q1

Company Raises Adjusted Gross Profit⁽¹⁾ 2026 FY Guidance by ~20%

DALLAS, TX, May 14, 2026 -- Hyperion DeFi, Inc. (NASDAQ: HYPD) (“Hyperion DeFi” or the “Company”), the first U.S. publicly listed DeFi company building on Hyperliquid, today reported results for the first quarter ending March 31, 2026.

“We are pleased to report continued scaling of our DeFi operating businesses, accretive balance sheet growth, and prudent cost management,” said Hyunsu Jung, CEO of Hyperion DeFi. Mr. Jung continued, “The opportunities to build on Hyperliquid are immense and expanding every day. More products and institutions are moving on-chain, and we continue to position ourselves as the premier institutional gateway to DeFi innovation. In light of our continued momentum, today we are increasing our guidance for our DeFi operating segments for full-year 2026, and we continue to anticipate achieving break-even cash flows by the end of the year.”

Q3’25, Q4’25, and Q1’26 Summary GAAP and Non-GAAP Financial Measures

(Figures in $)		Q3 2025			Q4 2025			Q1 2026
GAAP	Gross Profit		302,506			192,987			244,271
Non-GAAP	Adjusted Gross Profit⁽¹⁾		439,386			820,997			959,568
GAAP	HYPE Digital Assets		37,954,590			16,233,941			25,286,164
Non-GAAP	Gross HYPE Holdings⁽⁴⁾		77,751,604			47,837,901			71,037,227
Non-GAAP	Net Asset Value⁽⁹⁾		74,545,583			44,154,737			69,873,504
GAAP	Selling, General and Administrative Expense		2,594,130			4,530,542			4,493,604
Non-GAAP	Operating Expenses Excluding Stock-Based Compensation⁽⁵⁾		4,315,016			3,007,135			2,975,883
GAAP	Net Operating (Income) Expenses		(4,125,685	)		39,958,264			(8,487,848	)
Non-GAAP	Treasury Gains (Losses)⁽⁶⁾		11,868,872			(36,783,228	)		21,451,862
GAAP	Total Other Income (Expense), Net		2,197,391			(288	)		108,431
Non-GAAP	Adjusted Other Income (Expense)⁽⁷⁾		(42,240	)		48,717			52,585
GAAP	Net Income (Loss)		6,625,582			(39,765,565	)		8,840,550
Non-GAAP	Adjusted EBITDA⁽⁸⁾		7,951,003			(38,920,649	)		19,488,132

All figures in this press release are not audited. Throughout this document, totals may not sum due to rounding. Calculations are based on unrounded results.

This press release includes certain non-GAAP financial measures (including on a forward-looking basis) such as Adjusted Gross Profit, Gross HYPE Holdings, Net Asset Value, Operating Expenses Excluding Stock-Based Compensation, Treasury Gains (Losses), Adjusted Other Income (Expense), and Adjusted EBITDA. Please see “Footnotes” and “Non-GAAP Measures of Financial Performance” for reconciliations of non-GAAP financial measures to the most directly comparable GAAP financial measures and important additional information.

Adjusted Gross Profit⁽¹⁾Guidance	Q3'25			Q4'25			FY'25			Q1'26			Q2'26		Q3'26		Q4'26		FY'26 Guidance	2026 Guidance vs. 2025 Actual
Initial Guidance (Q4'25 A)	$	0.44	M	$	0.82	M	$	1.28	M		-			-		-		-	$4M - $6M	~4x
Current Guidance (Q1'26 A)	$	0.44	M	$	0.82	M	$	1.28	M	$	0.96	M		-		-		-	$5M - $7M	~5x

Adjusted Gross Profit⁽¹⁾(in $ thousands)	Q3'25			Q4'25			Q1'26			QoQ Growth
Ecosystem Rewards		-			285			150			-47	%
DeFi Monetization		<1			102			245			140	%
Yield Enhancement		78			79			211			165	%
Validator Commissions		21			49			40			-17	%
Staking Yield		340			305			313			2	%
Adjusted Gross Profit⁽¹⁾		439			821			960			17	%
Multiple vs. Staking Yield		1.3	x		2.7	x		3.1	x
% Earned in Cash*		18	%		22	%		48	%
HYPE Earned in Staking & Validating⁽²⁾		7,895			10,076			11,458			14	%
Effective Average HYPE Price In-Period⁽³⁾		45.76			35.12			30.82

*The portion of Adjusted Gross Profit⁽¹⁾ earned in cash, cash equivalents, and USDH⁽¹⁶⁾

Please see “Footnotes” and “Non-GAAP Measures of Financial Performance” sections for detailed definitions and reconciliations to the nearest GAAP Metric.

HYPE Treasury Over Time	09/30/25			12/31/25			3/31/26			5/11/26⁽¹⁴⁾
Gross HYPE Tokens⁽²⁾		1.72	M		1.88	M		1.94	M		2.00	M
HYPE Token Price	$	45.2		$	25.4		$	36.6		$	42.2
Gross HYPE Holdings⁽⁴⁾	$	77.8	M	$	47.8	M	$	71.0	M	$	84.5	M
Cash, Cash Equivalents, and USDH⁽¹⁶⁾		$8.2	M		$6.5	M		$9.1	M		$16.0	M

Please see “Footnotes” and “Non-GAAP Measures of Financial Performance” sections for detailed definitions and reconciliations to the nearest GAAP Metric.

HYPD Investment Thesis

Hyperion DeFi has executed three full quarters under our new DeFi strategy, with two sequential increases in our operating business and two sequential declines in our core costs. Our continued track record of outperformance versus peers through Q1’26 demonstrate that we have transcended the strategy and capabilities of a simple buy-and-hold “DAT” (digital asset treasury company), and instead, we are differentiated as the first U.S. publicly listed DeFi company building on the Hyperliquid blockchain.

We are unique among digital asset treasuries with five diversified operating business lines.

Our “Triple-Dip” HYPE deployment strategy, by which we earned approximately ~3.1x base staking income in Q1’26 versus ~2.7x in Q4’25, is possible because of our management’s unique ability to build on the Hyperliquid Blockchain.

Even as the Effective Average HYPE Price In-Period⁽³⁾ declined, we achieved +17% quarter-over-quarter growth in Adjusted Gross Profit⁽¹⁾, driven by ramping DeFi Monetization and Yield Enhancement strategies (each at >100% Q-o-Q growth).

The portion of our Adjusted Gross Profit⁽¹⁾ earned in cash, cash equivalents, and USDH⁽¹⁶⁾ increased from 22% in Q4’25 to 48% in Q1’26.

Beyond our growing HYPE treasury, our Hyperliquid ecosystem token holdings (such as KNTQ and HPL) uniquely position HYPD for upside in early-stage builders.

We operate with strong earnings leverage and a low cost base built for scale. We anticipate Operating Expenses Excluding Stock-Based Compensation⁽⁵⁾ to further decline below a quarterly run-rate of $3.0 million beginning in Q2’26 driven by the exit of legacy biotech operations.

We anticipate $5M-$7M Adjusted Gross Profit⁽¹⁾ in 2026, ~5x our 2025 FY results, which represents a +$1M increase in range from our Q4’25 earnings release.

Our businesses are designed to simultaneously promote and monetize adoption of the Hyperliquid blockchain. In Q1, our unique ability to “triple-dip” our HYPE tokens across multiple deployment strategies generated ~3.1x the income would have otherwise generated from staking in isolation. Our “HYPD Triple-Dip” strategy is:

Stake our HYPE

Deploy the staked HYPE into another business activity – our Validator, Yield Enhancement, or DeFi Monetization, and

Position ourselves to receive Ecosystem Rewards

Adjusted Gross Profit⁽¹⁾ in Q4’25 and Q1’26

Adjusted Gross Profit⁽¹⁾, a Non-GAAP Metric, aims to capture all of Hyperion DeFi’s value-add operating business activities beyond simply buying and holding HYPE tokens. In total, Adjusted Gross Profit⁽¹⁾ increased +17% quarter-over-quarter from $821 thousand in Q4’25 to $960 thousand in Q1’26.

Below is a summary of all five of our operating business activities included within Adjusted Gross Profit⁽¹⁾ in these periods:

Staking Yield: We stake our HYPE to our Validator and earn rewards.

In Q1’26, the Company earned 10,143 HYPE tokens from staking, up 16% quarter-over-quarter versus 8,437 in Q4’25.

On a dollar basis, our HYPE earned from staking generated $313 thousand Adjusted Gross Profit⁽¹⁾ in Q1’26 versus $305 thousand in Q4’25 (+2% quarter-over-quarter), while the Effective Average HYPE Price In-Period⁽³⁾ declined -12% from 35.12 in Q4’25 to 30.82 in Q1’26.

Validator Commissions: The Company operates its Validator under a Joint Validator Operators Agreement (together with Kinetiq and Pier Two) and earns commissions on rewards delivered to third-party tokens delegated to the Validator.

In Q1’26, the Company earned 1,315 HYPE tokens as validator commissions, a modest decline of -3% quarter-over-quarter versus 1,362 in Q4’25.

On a dollar basis, our HYPE earned from validator commissions generated $40 thousand Adjusted Gross Profit⁽¹⁾ in Q1’26 versus $49 thousand in Q4’25 (-17% quarter-over-quarter), given the Effective Average HYPE Price In-Period⁽³⁾ declined -12% from 35.12 in Q4’25 to 30.82 in Q1’26.

10.2 million HYPE tokens were delegated to our Validator as of April 30, 2026, and we are the Top 6 Hyperliquid Validator after the Hyper Foundation.

Yield Enhancement: The Company pursues accretive strategies to enhance yield earned on its tokens.

Yield Enhancement activities generated $211 thousand Adjusted Gross Profit⁽¹⁾ in Q1’26 versus $79 thousand in Q4’25 (+165% quarter-over-quarter).

Q1’26 and Q4’25 Yield Enhancement activities included multiple HYPE volatility strategies OTC and on-chain.

In Q1’26, we began executing within our Institutional Volatility Income Vault, in partnership with the Rysk protocol, further optimizing our Yield Enhancement capabilities while building the infrastructure to accommodate third-party execution within Rysk Premium in the future.

DeFi Monetization: The Company supports and monetizes Hyperliquid DeFi activity with sustainable, scalable practices.

DeFi Monetization activity generated $245 thousand Adjusted Gross Profit⁽¹⁾ in Q1’26 versus $102 thousand in Q4’25 (+140% quarter-over-quarter).

DeFi Monetization includes our Temporary HYPE Asset Use Agreements (“HAUS”) and protocol partnerships generating third-party fees.

In Q1’26, we entered into a HAUS agreement with Silhouette. We provided the use of HYPE tokens to the Silhouette aggregated trading account, allowing Silhouette to pass along reduced trading fees to its customers on the Silhouette platform, and entitling us to earn a portion of those fee savings as income, plus 100% of staking rewards.

Ecosystem Rewards: Through our active participation in the Hyperliquid DeFi ecosystem, the Company positions itself for the receipt of future potential token airdrops, protocol incentives, and other rewards that may become available periodically.

Ecosystem Rewards generated $150 thousand Adjusted Gross Profit⁽¹⁾ in Q1’26, versus $285 thousand in Q4’25.

We expect the quarter-over-quarter change in Ecosystem Rewards to be volatile given the unexpected timing of airdrops, token generation events, and other rewards activity.

In November 2025, we received 1,918,478 KNTQ tokens in Kinetiq’s airdrop token generation event.

In March 2026, we cumulatively received 10,000,000 HPL tokens from HyperLend in connection with multiple partnership and revenue-sharing agreements in connection with on-chain credit pools.

Silhouette is contractually obligated to award HYPD at least 1% of future token supply or equity, including affiliates and related parties.

Given our partnerships with other Hyperliquid ecosystem participants such as Rysk, and given that we are continuing to accrue additional Kinetiq points, we anticipate additional ecosystem rewards in 2026.

Non-GAAP Income Summary (Figures in $)	Q3 2025			Q4 2025			Q1 2026
Adjusted Gross Profit⁽¹⁾		439,386			820,997			959,568
Operating Expenses Excluding Stock-Based Compensation⁽⁵⁾		4,315,016			3,007,135			2,975,883
Treasury Gains (Losses)⁽⁶⁾		11,868,872			(36,783,228	)		21,451,862
Adjusted Other Income (Expense)⁽⁷⁾		(42,240	)		48,717			52,585
Adjusted EBITDA⁽⁸⁾		7,951,003			(38,920,649	)		19,488,132

Please see “Footnotes” and “Non-GAAP Measures of Financial Performance” sections for detailed definitions and reconciliations to the nearest GAAP Metric.

Q4’25 and Q1'26 Expense Summary Results

Operating Expenses Excluding Stock-Based Compensation⁽⁵⁾ declined (1%) quarter-over-quarter from $3.00 million in Q4’25 to $2.98 million in Q1’26.

Research and development expenses were $287 thousand in Q1’26 versus $189 thousand in Q4’25.

Selling, general, and administrative expenses excluding stock-based compensation decreased (5%) quarter-over-quarter, from $2.8 million in Q4’25 to $2.7 million in Q1’26.

We expect to wind down legacy biotech operations by the end of Q2’26.

Q4’25 and Q1'26 Treasury Summary

Gross HYPE Tokens⁽²⁾ increased from 1.88 million in Q4’25 to 1.94 million in Q1’26.

Our HYPE treasury has grown to over 2.00 million tokens as of May 11, 2026⁽¹⁴⁾.

Gross HYPE Holdings⁽⁴⁾ increased from $47.8 million as of Q4’25 to $71.0 million as of Q1’26 as the price of HYPE increased from $25.4 to $36.6 in Q1’26.

Net Asset Value⁽⁹⁾ increased from $44.2 million as of Q4’25 to $69.9 million as of Q1’26.

Treasury Gains (Losses)⁽⁶⁾ was $21.5 million in Q1’26 versus ($36.8 million) in Q4’25.

Q4'25 and Q1’26 Net Income (Loss) and Adjusted EBITDA⁽⁸⁾

Q1’26 Net Income of $8.8 million compares to Q4’25 Net Loss of ($39.8 million).

Q1’26 Adjusted EBITDA⁽⁸⁾ of $19.5 million compares to Q4’25 Adjusted EBITDA⁽⁸⁾ of ($38.9 million)

The primary reconciliation of Net Income to Adjusted EBITDA⁽⁸⁾ is our HYPE Liquid Staking Tokens (LSTs), for which the GAAP carrying value is the low-water-mark price of HYPE, as detailed further in our GAAP to Non-GAAP reconciliations section at the end of this release.

Q1’26 Net Income Attributable to Common Shareholders of $3.3 million compares to Q4’25 Net Loss Attributable to Common Shareholders of ($40.6 million).

Q1’26 Net Income per Common Share of $0.30 on a basic basis (10,610,679 weighted average shares) and $0.26 on a diluted basis (12,686,142 weighted average shares), compares to Q4’25 Net Loss per Share of ($6.29) on 6,452,733 on weighted average shares outstanding.

As of May 11, 2026, there are 15,025,498 outstanding shares of common stock.

Q4’25 and Q1'26 Cash Flows Summary

Operating Activities used $4.2 million net cash in Q1’26 versus $4.1 million in Q4’25.

Q1’26 Operating Cash Flow included $1.5 million net increase in the levels of operating assets (including acquiring additional USDH stablecoin⁽¹⁶⁾), without which, Net Cash Used in Operating Activities would have been $2.7 million.

Our cash, cash equivalents, and USDH⁽¹⁶⁾ totaled $9.1 million as of Q1’26 versus $6.5 million as of Q4’25.

As of May 11, 2026, our cash, cash equivalents, and USDH⁽¹⁶⁾ totaled approximately $16.0 million⁽¹⁴⁾.

Net Cash Used in Investing Activities to purchase HYPE was $1.5 million in Q1’26 versus $6.3 million in Q4’25.

QTD Q2’26 as of May 11, 2026, we have purchased $2.5 million in HYPE.

Net Cash Provided by Financing Activities was $6.6 million in Q1’26 (primarily from our “at-the-market” offering) versus $9.4 million in Q4’25.

Through May 11, 2026, QTD Q2’26 we have raised approximately $1.9 million net proceeds from the sale of 492,783 shares via our “at-the-market” offering⁽¹⁴⁾.

On May 7, 2026, we closed a public offering of 2,777,778 common shares and received approximately $8.7 million in net proceeds⁽¹⁴⁾.

Conference Call & Webcast

Hyperion DeFi, Inc. will hold its earnings conference call and webcast for the first quarter ended March 31, 2026 on Thursday, May 14, 2026 at 8:00 a.m. Eastern Time. A slide presentation that includes supplemental financial information and reconciliations of certain non-GAAP measures to their most directly comparable GAAP measures can be accessed through the Company’s Investor Relations website at https://ir.hyperiondefi.com/events-and-presentations along with information for the conference call. A webcast of the call will be archived and available through May 28, 2026 at 11:59 p.m. Eastern Time on the Company's website.

Presentation

All growth rates represent quarter-over-quarter comparisons, except as otherwise noted. All amounts in tables are presented in U.S. dollars, rounded to the nearest dollar, except as otherwise noted. As a result, certain amounts and rates may not sum or recalculate using the rounded dollar amounts provided. All numbers in this press release are not audited.

About the Hyperliquid Platform and the HYPE Token

Hyperliquid is a next-generation layer one blockchain optimized for high frequency, transparent trading. The blockchain includes fully on-chain perpetual futures and spot order books, with every order, cancel, trade, and liquidation occurring within 70 millisecond block times. It also hosts the HyperEVM, a general-purpose smart contract platform that supports permissionless decentralized financial applications akin to Ethereum.

HYPE is the native token of Hyperliquid. Staked HYPE provides utility for users via reduced trading fees and increased referral bonuses. As of May 2026, more than 44 million HYPE have been autonomously purchased and sequestered by the blockchain with the trading fees generated on the network’s central limit order books.

About Hyperion DeFi, Inc.

Hyperion DeFi, Inc. is the first U.S. publicly listed DeFi company building on Hyperliquid. The Company provides investors with streamlined access to the Hyperliquid ecosystem, one of the fastest growing, highest revenue-generating blockchains in the world. Shareholders benefit from compounding exposure to HYPE, both from its native staking yield and additional revenues generated from its unique on-chain utility.

For more information, please visit Hyperiondefi.com or follow @hyperiondefi on X.

Forward Looking Statements; Disclaimer

Except for historical information, all the statements, expectations and assumptions contained in this press release are forward-looking statements. Forward-looking statements include, but are not limited to, statements that express our intentions, beliefs, expectations, strategies, predictions or any other statements, our future activities or other future events or conditions, including the viability of, and risks associated with, our cryptocurrency treasury strategy, the growth and revenue potential of the Hyperliquid ecosystem and the growth prospects of the Company. These statements are based on current expectations, estimates and projections about our business based, in part, on assumptions made by management. These statements are not guarantees of future performance and involve risks, uncertainties and assumptions that are difficult to predict. Therefore, actual outcomes and results may, and in some cases are likely to, differ materially from what is expressed or forecasted in the forward-looking statements due to numerous factors discussed from time to time in documents which we file with the U.S. Securities and Exchange Commission.

Any forward-looking statements speak only as of the date on which they are made, and except as may be required under applicable securities laws, Hyperion DeFi does not undertake any obligation to update any forward-looking statements.

Certain information contained in this press release relates to or is based on studies, publications, surveys and other data obtained from third-party sources and Hyperion DeFi’s own internal estimates and research. While Hyperion DeFi believes these third-party studies, publications, surveys and other data to be reliable as of the date of this press release, it has not independently verified, and makes no representation as to the adequacy, fairness, accuracy or completeness of, any information obtained from third-party sources. In addition, no independent source has evaluated the reasonableness or accuracy of Hyperion DeFi’s internal estimates or research and no reliance should be made on any information or statements made in this press release relating to or based on such internal estimates and research. You should conduct your own investigation and analysis of Hyperion DeFi, its business, prospects, results of operations and financial condition. In furnishing this information, Hyperion DeFi does not undertake any obligation to provide you with access to any additional information (including forward-looking information and any projections contained herein) or to update or correct the information.

Hyperion DeFi, Inc. Investor Contact:

Jason Assad

Hyperion DeFi, Inc.

IR@hyperiondefi.com

(678) 570-6791

Hyperion DeFi, Inc.

Condensed Balance Sheets

(unaudited)

	March 31,			December 31,
	2026			2025
	(unaudited)
Assets

Current Assets
Cash and cash equivalents	$	7,380,922		$	6,443,467
Prepaid expenses and other current assets		1,423,025			802,342
Total Current Assets		8,803,947			7,245,809

Digital assets		25,422,127			16,345,347
Digital assets receivable, net		10,376,105			6,935,131
Digital intangible assets		16,033,758			20,591,555
Digital intangible assets receivable, net		8,907,419			—
Operating lease right-of-use asset		340,407			415,998
Other assets		182,200			230,416
Total Assets	$	70,065,963		$	51,764,256

Liabilities and Stockholders’ Equity

Current Liabilities:
Accounts payable	$	428,266		$	317,900
Accrued expenses and other current liabilities		2,070,181			1,871,106
Operating lease liabilities - current portion		465,245			512,007
Notes payable - current portion		1,509,326			—
Total Current Liabilities		4,473,018			2,701,013
Notes payable - non-current portion		6,965,557			7,796,136
Operating lease liabilities, non-current portion		132,424			206,600
Total Liabilities		11,570,999			10,703,749

Commitments and contingencies (Note 9)

Stockholders’ Equity
Preferred stock, $0.0001 par value, 60,000,000 shares authorized; Series A Non-Voting Convertible Preferred Stock, 5,435,898 shares designated; 5,235,897 and 5,435,897 shares issued and outstanding as of March 31, 2026 and December 31, 2025, respectively with a liquidation preference of $50,768,000 as of March 31, 2026		524			544
Common stock, $0.0001 par value, 600,000,000 shares authorized; 11,428,482 shares issued and outstanding as of March 31, 2026;8,762,329 shares issued and 8,680,005 shares outstanding as of December 31, 2025, respectively		1,143			876
Additional paid-in-capital		290,277,174			281,937,072
Treasury stock, at cost, 0 and 82,324 shares as of March 31, 2026 and December 31, 2025, respectively		—			(253,558	)
Accumulated deficit		(231,783,877	)		(240,624,427	)
Total Stockholders’ Equity		58,494,964			41,060,507
Total Liabilities and Stockholders’ Equity	$	70,065,963		$	51,764,256

Hyperion DeFi, Inc.

Condensed Statements of Operations

(unaudited)

	For the Three Months Ended
	March 31,
	2026			2025
Revenue	$	244,271		$	14,720
Cost of revenue		—			(48	)
Gross Profit		244,271			14,672

Operating (Income) Expenses:
Research and development		286,764			673,043
Selling, general and administrative		4,493,604			2,372,322
Realized gain - digital assets and digital assets receivable		(3,623,764	)		—
Unrealized gain - digital assets		(10,973,979	)		—
Unrealized gain – digital intangible assets receivable		(367,251	)		—
Impairment loss - digital intangible assets		1,231,668			—
Net gains (losses) on derivative instruments		(39,401	)		—
Provision for credit losses		504,511			—
Net Operating (Income) Expenses		(8,487,848	)		3,045,365
Income (Loss) From Operations		8,732,119			(3,030,693	)

Other Income (Expense):
Other income, net		90,133			3,687
Gain on extinguishment of liabilities		—			89,623
Interest expense		(225,869	)		(581,499	)
Interest income		244,167			35,349
Total Other Income (Expense), Net		108,431			(452,840	)

Net Income (Loss)		8,840,550			(3,483,533	)
Dividend to preferred stockholders		(815,297	)		—
Net Income (Loss) Attributable to Participating Securities		8,025,253			(3,483,533	)
Less: income allocated to preferred stockholders		(4,789,742	)		—
Net Income (Loss) Available to Common Stockholders	$	3,235,511		$	(3,483,533	)


Net Loss per Share - Basic	$	0.30		$	(1.59	)
Net Loss per Share - Diluted	$	0.26		$	(1.59	)

Shares Outstanding - Basic		10,610,679			2,188,938
Shares Outstanding - Diluted		12,686,142			2,188,938

Hyperion DeFi, Inc.

Condensed Statements of Stockholders’ Equity (Deficit)

(unaudited)

	For the Three Months Ended March 31, 2026
													Additional												Total
	Preferred Stock						Common Stock						Paid-In			Treasury Stock						Accumulated			Stockholders’
	Shares			Amount			Shares			Amount			Capital			Shares			Amount			Deficit			Equity
Balance - January 1, 2026		5,435,897		$	544			8,762,329		$	876		$	281,937,072			82,324		$	(253,558	)	$	(240,624,427	)	$	41,060,507
Issuance of common stock in At the Market offering [1]		—			—			1,859,993			186			6,665,196			—			—			—			6,665,382
Issuance of common stock for payment in kind of preferred stock dividend		—			—			244,518			25			939,312			—			—			—			939,337
Issuance of common stock from the delivery of vested restricted stock units		—			—			33,516			3			(3	)		—			—			—			—
Issuance of common stock from conversion of preferred stock		(200,000	)		(20	)		600,000			60			(40	)		—			—			—			—
Retirement of treasury shares		—			—			(82,324	)		(8	)		(253,550	)		(82,324	)		253,558			—			—
Stock-based compensation:
Amortization of stock option awards		—			—			—			—			80,880			—			—			—			80,880
Amortization of restricted stock units		—			—			—			—			1,690,852			—			—			—			1,690,852
Issuance of common stock to vendors as consideration for service provided		—			—			10,450			1			32,752			—			—			—			32,753
Preferred stock dividend ($0.16 per preferred share outstanding)		—			—			—			—			(815,297	)		—			—			—			(815,297	)
Net income		—			—			—			—			—			—			—			8,840,550			8,840,550
Balance - March 31, 2026		5,235,897		$	524			11,428,482		$	1,143		$	290,277,174			—		$	—		$	(231,783,877	)	$	58,494,964

	For the Three Months Ended March 31, 2025
										Additional										Total
	Preferred Stock				Common Stock					Paid-In			Treasury Stock				Accumulated			Stockholders’
	Shares		Amount		Shares			Amount		Capital			Shares		Amount		Deficit			Deficit
Balance - January 1, 2025		—	$	—		1,506,369		$	151	$	182,213,889			—	$	—	$	(195,309,992	)	$	(13,095,952	)
Issuance of common stock in At the Market offering [2]		—		—		1,127,100			113		5,663,153			—		—		—			5,663,266
Induced exercise of stock warrants [3]		—		—		197,118			19		922,731			—		—		—			922,750
Reverse stock split settlement of fractional shares		—		—		(41	)		—		(160	)		—		—		—			(160	)
Warrant modification and additional warrants-incremental value [4]		—		—		—			—		1,194,102			—		—		—			1,194,102
Warrant modification and additional warrants-in issuance costs for inducement [5]		—		—		—			—		(1,194,102	)		—		—		—			(1,194,102	)
Stock-based compensation		—		—		—			—		279,628			—		—		—			279,628
Net loss		—		—		—			—		—			—		—		(3,483,533	)		(3,483,533	)
Balance - March 31, 2025		—	$	—		2,830,546		$	283	$	189,079,241			—	$	—	$	(198,793,525	)	$	(9,714,001	)

[1]

Includes gross proceeds of $6,981,098 less total issuance costs of $315,716.

[2]

Includes gross proceeds of $5,851,007 less total issuance costs of $187,741.

[3]

Includes gross proceeds of $1,039,206 less total issuance costs of $116,456.

[4]

Incremental value from the warrant inducement entered into on January 16, 2025.

[5]

Non-cash warrant modification and additional warrants issuance costs related to the warrant inducement are shown as a separate line item for clarity.

Hyperion DeFi, Inc.

Condensed Statements of Cash Flows

(unaudited)

	For the Three Months Ended
	March 31,
	2026			2025
Cash Flows From Operating Activities
Net income (loss)	$	8,840,550		$	(3,483,533	)
Adjustments to reconcile net income (loss) to net cash and cash equivalents used in operating activities:
Stock-based compensation		1,804,485			279,628
Change in fair value of shares issued for accrued dividend		146,719			—
Amortization of debt discount		55,461			277,972
Non-cash lease expense		75,591			75,591
Provision for credit losses		504,511			—
Gain on extinguishment of liabilities		—			(89,623	)
Realized gain - digital assets		(3,623,764	)		—
Unrealized gain - digital assets		(10,973,979	)		—
Unrealized gain – digital intangible assets receivable		(367,251	)
Net gains on derivative instruments		(39,401	)		—
Impairment loss - digital intangible assets		1,231,668			—
Non-cash revenue, net		(244,271	)		—
Non-cash portion of other income		(6,041	)		—
Non-cash interest income from digital assets receivable		(198,957	)		—
Paid-in-kind interest expense		83,672			198,829
Changes in operating assets and liabilities:
Prepaid expenses and other current assets		(1,542,190	)		(577,321	)
License fee and expense reimbursements receivables		—			(960	)
Accounts payable		110,366			(999,807	)
Accrued expenses and other current liabilities		67,117			28,814
Lease liabilities		(120,938	)		(152,436	)
Net Cash and Cash Equivalents Used In Operating Activities		(4,196,652	)		(4,442,846	)

Cash Flows From Investing Activities
Purchase of digital assets		(1,472,835	)		—
Net Cash and Cash Equivalents Used In Investing Activities		(1,472,835	)		—

Cash Flows From Financing Activities
Proceeds from sale of common stock in At the Market offering		6,981,098			5,851,007
Proceeds from induced exercise of stock warrants		—			1,039,206
Payment of issuance costs for At the Market offering		(315,716	)		(187,741	)
Repayments of notes payable		(58,440	)		(152,279	)
Payment of issuance costs for debt modification		—			(177,228	)
Payment of cash issuance costs for induced exercise of stock warrants		—			(116,456	)
Reverse stock split settlement of fractional shares		—			(160	)
Net Cash and Cash Equivalents Provided By Financing Activities		6,606,942			6,256,349
Net Increase in Cash and Cash Equivalents		937,455			1,813,503
Cash and Cash Equivalents - Beginning of Period		6,443,467			2,121,463
Cash and Cash Equivalents - End of Period	$	7,380,922		$	3,934,966

Hyperion DeFi, Inc.

Condensed Statements of Cash Flows, continued

(unaudited)

	For the Three Months Ended
	March 31,
	2026		2025
Supplemental Disclosure of Cash Flow Information:
Cash paid during the period for:
Interest	$	86,737	$	—
Taxes	$	—	$	—

Supplemental Disclosure of Non-Cash Investing and Financing Activities
Modification date carrying value of extinguished Avenue Loan	$	—	$	10,262,280
Modification date fair value of modified Avenue Loan	$	—	$	10,172,657
Transfer of digital assets into digital intangible assets receivable	$	8,863,235	$	—
Deposits of USDH into Hyperion Rysk Vault	$	1,765,075	$	—
Redemption of digital assets from Hyperion Rysk Vault	$	151,377	$	—
Warrant modification and additional warrants - incremental value	$	—	$	1,194,102
Prepaid insurance financed by note payable	$	598,055	$	—
Common stock issued for accrued dividends payable	$	939,337	$	—
Accrued dividend payable to preferred stockholders	$	815,297	$	—
Treasury shares retired	$	253,558	$	—
Deposits of digital assets into liquid staking activities	$	224,011	$	—
Liability for digital assets received from lender, prior to loan origination	$	150,163	$	—
Common stock issued upon conversion of preferred stock	$	60	$	—
Receipt of digital assets from liquid staking activities	$	4	$	—
Issuance of common stock upon vesting of restricted stock units	$	3	$	—

Hyperion DeFi Non-GAAP Measures of Financial Performance and Supplemental Disclosures

Reconciliation of GAAP Revenue to Non-GAAP Adjusted Gross Profit⁽¹⁾ (unaudited)

	For the Three Months Ended
(Figures in $)	September 30, 2025		December 31, 2025		March 31, 2026
Gross Profit		302,506		192,987		244,271
Add: Accumulated but unrealized staking yield on LSTs⁽¹⁰⁾		58,771		172,463		154,806
Add: Net gains on derivative instruments		78,109		79,461		39,401
Add: Accumulated but unrealized yield enhancement activity⁽¹⁵⁾		-		-		171,970
Add: Operating Income from airdrops		-		285,450		-
Add: Receipt of HPL tokens pursuant to partnership agreements		-		-		150,163
Add: Interest Income from DeFi Monetization activity		-		90,636		198,957
Adjusted Gross Profit⁽¹⁾		439,386		820,997		959,568

Note: See “Footnotes” section for detailed explanations and definitions.

Q1’26 Reconciliation of GAAP HYPE Digital Assets to Non-GAAP Gross HYPE Holdings⁽⁴⁾ (unaudited)

	As of March 31, 2026
	Value $		Token Count		Token Price $
HYPE digital assets		25,286,164		690,505		36.62
Add:
HYPE digital assets receivable*		11,071,200		302,327		36.62
HYPE digital intangible assets receivable**		9,230,486		250,000		20.66
HiHYPE at Carrying Value		7,785,852		378,277		20.58
kHYPE at Carrying Value		5,693,449		275,434		20.67
kmHYPE at Carrying Value		597,068		28,888		20.67
Unrealized accretion (dilution) expected upon LST to HYPE reconversion⁽¹¹⁾		11,373,007		14,421		N.M.***
Gross HYPE Holdings⁽⁴⁾		71,037,344
Gross HYPE Tokens⁽²⁾				1,939,851		36.62

Note: See “Footnotes” section for detailed explanations and definitions.

Memo: Unrealized accretion (dilution) expected upon LST to HYPE reconversion as of December 31, 2025			3,499,665
Memo: In-Period Change in unrealized accretion (dilution) expected upon LST to HYPE reconversion			7,873,342

*Presented gross of $586,774 allowance for credit losses and $108,321 unamortized nonrefundable upfront fee.

**Presented gross of $323,067 allowance for credit losses.

***Throughout this release, N.M. is the abbreviation for “Not Meaningful”.

Q4’25 Reconciliation of GAAP HYPE Digital Assets to Non-GAAP Gross HYPE Holdings⁽⁴⁾ (unaudited)

	As of December 31, 2025
	Value $		Token Count		Token Price
HYPE - Digital Assets		16,233,941		638,352		25.43
Add:
HYPE digital asset receivable*		7,647,740		300,725		25.43
HiHYPE at carrying value		8,437,277		398,277		21.18
kHYPE at carrying value		11,369,458		505,434		22.49
kmHYPE at carrying value		649,820		28,888		22.49
Add: Unrealized accretion (dilution) expected upon future LST to HYPE Token reconversion⁽¹¹⁾		3,499,665		9,410		N.M.
Gross HYPE Holdings⁽⁴⁾		47,837,901
Gross HYPE Tokens⁽²⁾				1,881,086		25.43

Note: See “Footnotes” section for detailed explanations and definitions.

Unrealized accretion (dilution) expected upon LST to HYPE reconversion as of Q3’25			4,912,082
In-Period Change in unrealized accretion (dilution) expected upon LST to HYPE vs. Q3’25			(1,412,417	)

*Presented gross of $405,331 allowance for credit losses and $307,278 unamortized nonrefundable upfront fee.

Q3’25 Reconciliation of GAAP HYPE Digital Assets to Non-GAAP Gross HYPE Holdings⁽⁴⁾ (unaudited)

	As of September 30, 2025
	Value $		Token Count		Token Price
HYPE digital assets		37,954,590		839,889		45.19
Add: HiHYPE at Carrying Value		34,884,932		877,871		39.74
Add: Unrealized accretion (dilution) expected upon future LST to HYPE Token reconversion⁽¹¹⁾		4,912,082		2,788		N.M.
Gross HYPE Holdings⁽⁴⁾		77,751,604
Gross HYPE Tokens⁽²⁾				1,720,549		45.19

Note: See “Footnotes” section for detailed explanations and definitions.

Unrealized accretion (dilution) expected upon LST to HYPE reconversion as of June 30, 2025*

4,912,082

*The Company did not hold any LSTs on or prior to June 30, 2025. Therefore, as of September 30, 2025, the in-period change in unrealized accretion (dilution) expected upon LST to HYPE Token Reconversion is the same as the absolute figure.

Reconciliation of GAAP Selling, General and Administrative expense to Non-GAAP Operating Expense Excluding Stock-Based Compensation⁽⁵⁾ (unaudited)

	For the Three Months Ended
(Figures in $)	September 30, 2025		December 31, 2025			March 31, 2026
Selling, general and administrative expense		2,594,130		4,530,542			4,493,604
Subtract: stock-based compensation expense		1,347,031		(1,712,361	)		(1,804,485	)
Add: research and development expense		373,855		188,954			286,764
Operating Expense Excluding Stock-Based Compensation⁽⁵⁾		4,315,016		3,007,135			2,975,883

Note: See “Footnotes” section for detailed explanations and definitions.

Supplemental Disclosure of Disaggregated Stock-Based Compensation (unaudited)

	For the Three Months Ended
(Figures in $)	September 30, 2025			December 31, 2025		March 31, 2026
Mark-to-Market Adjustment of Vested but Undelivered Awards		(2,140,000	)		-		-
Amortization of Unearned Executive Milestone Awards		209,648			997,563		997,563
All Remaining Stock-Based Compensation		583,321			714,798		806,922
Total Stock-Based Compensation		(1,347,031	)		1,712,361		1,804,485

Reconciliation of GAAP Net Operating (Expenses) Income to Non-GAAP Treasury Gains (Losses)⁽⁶⁾ (unaudited)

	For the Three Months Ended
(Figures in $)	September 30, 2025			December 31, 2025			March 31, 2026
Net Operating Income (Expenses)		4,125,685			(39,958,264	)		8,487,848
Add Back:
Research and development expense		373,855			188,954			286,764
Selling, general and administrative expense		2,594,130			4,530,542			4,493,604
Provision for credit losses		-			405,331			504,511
In-Period Change in unrealized accretion (dilution) expected upon LST to HYPE reconversion		4,912,082			(1,412,417	)		7,873,342
Subtract:
Accumulated but unrealized staking yield on LSTs⁽¹⁰⁾		(58,771	)		(172,463	)		(154,806	)
Operating Income from airdrops		-			(285,450	)		-
Net gains on derivative instruments		(78,109	)		(79,461	)		(39,401	)
Treasury Gains (Losses)⁽⁶⁾		11,868,872			(36,783,228	)		21,451,862

Note: See “Footnotes” section for detailed explanations and definitions.

Reconciliation of GAAP Total Other Income (Expense), Net to Non-GAAP Adjusted Other Income (Expense)⁽⁷⁾ (unaudited)

	For the Three Months Ended
(Figures in $)	September 30, 2025			December 31, 2025			March 31, 2026
Total Other Income (Expense), Net		2,197,391			(288	)		108,431
Add back:
Interest expense		223,080			224,799			225,869
Reduction in life sciences liabilities⁽¹²⁾		(2,407,154	)		-			(225,173	)
Other non-recurring items⁽¹³⁾		(55,557	)		(85,158	)		142,415
Subtract: Interest Income from DeFi Monetization activities		-			(90,636	)		(198,957	)
Adjusted Other Income (Expense)⁽⁷⁾		(42,240	)		48,717			52,585

Note: See “Footnotes” section for detailed explanations and definitions.

Reconciliation of GAAP Net Income to Non-GAAP Adjusted EBITDA⁽⁸⁾ (unaudited)

	For the Three Months Ended
(Figures in $)	September 30, 2025			December 31, 2025			March 31, 2026
Net Income (Loss)		6,625,582			(39,765,565	)		8,840,550
Add back:
Stock-based compensation		(1,347,031	)		1,712,361			1,804,485
Interest expense		223,080			224,799			225,869
Provision for credit losses		-			405,331			504,511
Income Taxes		-			-
Depreciation and amortization expense		-			-
Reduction in life sciences liabilities⁽¹²⁾		(2,407,154	)		-			(225,173	)
Other non-recurring items⁽¹³⁾		(55,557	)		(85,158	)		142,415
Add:
In-Period Change in unrealized accretion (dilution) expected upon LST to HYPE reconversion		4,912,082			(1,412,417	)		7,873,342
Accumulated but unrealized yield enhancement activity⁽¹⁵⁾		-			-			171,970
Receipt of HPL tokens pursuant to partnership agreements		-			-			150,163
Adjusted EBITDA⁽⁸⁾		7,951,003			(38,920,649	)		19,488,132

Note: See “Footnotes” section for detailed explanations and definitions.

*Does not include Amortization of Operating Lease.

Reconciliation of GAAP HYPE digital assets, as adjusted to Gross HYPE Holdings⁽⁴⁾, to Non-GAAP Net Asset Value⁽⁹⁾ (unaudited)

(Figures in $)	September 30, 2025			December 31, 2025			March 31, 2026
Gross HYPE Holdings⁽⁴⁾		77,751,604			47,837,901			71,037,227
Add: KNTQ & sKNTQ at Carrying Value		-			111,406			193,780
Add: HPL & sHPL at Carrying Value		-			-			149,820
Add: Hyperion Rysk Vault Shares at Cost Basis*		-			-			1,615,075
Add: Current Assets		9,085,767			7,245,809			8,803,947
Subtract: Current Liabilities**		(4,037,092	)		(2,701,013	)		(4,509,992	)
Subtract: Notes Payable***		(8,254,696	)		(8,339,366	)		(7,416,353	)
Net Asset Value⁽⁹⁾		74,545,583			44,154,737			69,873,504

Note: See “Footnotes” section for detailed explanations and definitions.

*Digital intangible assets representing claims on USDH held in the Hyperion Rysk Institutional Volatility Income Vault, bearing the technical name “WHYPE-USDH-USDH-P-H-HL”.

**Includes Notes payable - current portion as of March 31, 2026; does not subtract debt discount of $36,974 as of March 31, 2026.

***Non-current portion; does not subtract debt discount of $598,691 as of September 30, 2025, $543,230 as of December 31, 2025, or $450,796 as of March 31, 2026.

Footnotes

“Adjusted Gross Profit” is a non-GAAP measure. Adjusted Gross Profit is defined as all in-period gross profit generated by the Company’s operations excluding buying digital assets and associated mark-to-market price movements. Such activities include staking yield, validator operations, yield enhancement activity, DeFi monetization partnerships, ecosystem rewards, and (prior to 2026) life sciences operations. It is reconciled to the GAAP measure “Gross Profit” by (i) adding accumulated but unrealized staking yield on LSTs, (ii) adding Net gains on derivative instruments, (iii) adding accumulated but unrealized yield enhancement activity as further described in Footnote 15, (iv) adding Operating Income from airdrops, (v) adding the Company’s receipt of HPL tokens pursuant to its partnership agreements with HyperLend, and (vi) adding the portion of GAAP “Interest Income” generated from digital assets receivables. We believe “Adjusted Gross Profit” is a helpful financial measure to our management and investors as it aims to capture all in-period gross profit generated by our active operational strategies without the impact of (i) the temporary GAAP earnings volatility of HYPE to LST conversion and LST to HYPE reconversion, (ii) the temporary GAAP earnings volatility of depositing and redeeming USDH versus Hyperion Rysk Vault Shares and delays in recognition of upfront received premium on expired sold HYPE put and call options, (iii) the over-time GAAP recognition of the Company’s receipt of HPL tokens, and (iv) dispersed GAAP presentment of our operational strategies across various Statements of Operations sections, or (iv) the impacts of realized or unrealized gains or losses on our digital assets. We believe Adjusted Gross Profit is a critical metric to quantify and compare our core operational activities between periods. In the Company’s earnings release and earnings supplement for three months ended September 30, 2025 and December 31, 2025, we previously reconciled Non-GAAP “Adjusted Gross Profit” to GAAP “Revenue”. Given changes in GAAP presentment related to staking and validating activities, we believe for the three months ended March 31, 2026, the closest comparable GAAP metric to Adjusted Gross Profit is Gross Profit.

The following are unaudited supplemental operating disclosures: Gross HYPE Tokens, the number of HYPE tokens staked at the Kinetiq x Hyperion Validator, Validator Commissions in HYPE, Staking Yield in HYPE, and HYPE Earned in Staking & Validating.

Calculated as the sum of the in-period Non-GAAP Adjusted Gross Profit components of (a) Validator Commissions plus (b) Staking Yield (such figures being expressed in-period in US Dollars), divided by the sum of (c) Validator Commissions in HYPE plus (d) Staking Yield in HYPE.

“Gross HYPE Holdings” is a non-GAAP measure. Gross HYPE Holdings is defined as the gross market value of the Company’s HYPE assuming (a) all temporary HYPE token use agreements are exited, (b) all collateralized OTC HYPE derivatives are exited (and such LST collateral returned to the Company), and (c) all LSTs were converted back to HYPE tokens as of the end of each respective reporting quarter. It is reconciled to the GAAP measure “HYPE digital assets” by adding (i) HYPE digital assets receivable (without subtracting allowance for credit loss or unamortized nonrefundable upfront fees), (ii) HYPE digital intangible assets receivable (without subtracting allowance for credit loss), (iii) HYPE LSTs at carrying value (including without limitation HiHYPE, kHYPE, and kmHYPE) and (iv) the unrealized accretion (dilution) expected upon LST to HYPE reconversion as of the end of each respective reporting quarter. We believe Gross HYPE Holdings is a helpful non-GAAP financial measure to our management and investors because it eliminates the temporary HYPE value impacts caused by our DeFi Monetization and Yield Enhancement token movements as well as the conversion and reconversion between HYPE tokens and LSTs, which (a) causes staking yield on our LSTs not to be recognized in-period in accordance with GAAP and (b) does not recognize upward mark-to-market movements in underlying HYPE tokens given LSTs are carried at the lower of cost basis or impaired value. As such, it provides useful information about our balance sheet, allows for greater transparency with respect to important metrics used by our management for financial, risk management and operational decision-making, and provides an additional tool for investors to understand and compare our operating results across reporting periods.

"Operating Expenses Excluding Stock-Based Compensation" is a non-GAAP measure. Operating Expenses Excluding Stock-Based Compensation is defined as the Company's operational expenses in-period excluding treasury value movements and stock-based compensation. It is reconciled to the GAAP measure “Selling, general and administrative expense” by (i) subtracting stock-based compensation expense and (ii) adding Research and development expense. Operating Expenses Excluding Stock-Based Compensation provides a metric of total operating expenditures in-period without the impact of treasury value movement or stock-based compensation, thereby creating a helpful metric for operational expense comparisons between different periods for our management and investors.

"Treasury Gains (Losses)" is a non-GAAP measure. Treasury Gains (Losses) is defined as the gross mark-to-market change in the company's digital asset treasury portfolio each period, without accounting for temporary GAAP impacts due to HYPE to LST conversion (or LST to HYPE reconversion) or operating income driven by airdrops or yield enhancement activity. It is reconciled to the GAAP measure “Net Operating Income (Expenses)" by (a) adding (i) Research and development expense, (ii) Selling, general, and administrative expense, (iii) Provision for credit losses, and (iv) the in-period change in unrealized accretion (dilution) expected upon LST to HYPE reconversion, and (b) subtracting (i) accumulated but unrealized staking yield on LSTs, (ii) Operating Income from airdrops, and (iii) Net gains on derivative instruments. Following these adjustments, Treasury Gains (Losses) is a singular metric that can present mark-to-market treasury changes in isolation, which we believe is a helpful metric for management and investors given our large digital asset treasury position and the volatile nature of digital assets.

"Adjusted Other Income (Expense)" is a non-GAAP measure. Adjusted Other Income (Expense) reflects management’s view of recurring activities outside of core operating income and operating expenses. It is reconciled to the GAAP measure "Total Other Income (Expense), Net" by (a) adding back (i) interest expense, (ii) non-recurring gains from reductions in life sciences liabilities, and (iii) other non-recurring items which we do not consider material in nature, and (b) subtracting the portion of GAAP “Interest Income” generated from digital assets receivables. The items added back to Adjusted Other Income (Expense) are excluded because they are non-cash in nature, or because the amount and timing of these items are unpredictable, are not driven by core results of operations, and render comparisons with prior periods and competitors less meaningful. The item subtracted from Adjusted Other Income (Expense) is already captured in the Non-GAAP metric “Adjusted Gross Profit”, as further described in Footnote 1. We believe Adjusted Other Income (Expense) provides a helpful view to management and investors regarding recurring and ongoing income and expense items outside of operating income and operating expenses, presented in a way to compare these elements over time.

“Adjusted EBITDA” is a non-GAAP measure. Adjusted EBITDA is meant to reflect management’s view of recurring business activities and a more comparable view of the mark-to-market impacts on our digital asset treasury holdings in-period. It is reconciled to the GAAP measure “Net Income (Loss)” by removing (i) stock-based compensation, (ii) interest expense, (iii) provision for credit losses, (iv) income taxes, (v) depreciation and amortization expense (excluding amortization of operating lease), (vi) non-recurring gains from reductions in life sciences liabilities, and (vii) other non-recurring items which we do not consider material in nature; and, it adds in (i) the in-period change in unrealized accretion (dilution) expected upon LST to HYPE reconversion, (ii) accumulated but unrealized yield enhancement activity as further described in Footnote 15, and (iii) the Company’s receipt of HPL tokens pursuant to its partnership agreements with HyperLend. The items excluded from our Adjusted EBITDA are excluded because they are non-cash in nature, or because the amount and timing of these items are unpredictable, are not driven by core results of operations, and render comparisons with prior periods and competitors less meaningful. The items added to Adjusted EBITDA are included to give a more complete picture of our in-period operations and mark-to-market impacts on our digital assets, disregarding (i) the temporary GAAP earnings volatility of HYPE to LST conversion and LST to HYPE reconversion, (ii) the temporary GAAP earnings volatility of depositing and redeeming USDH versus Hyperion Rysk Vault Shares and delays in recognition of upfront received premium on expired sold HYPE put and call options, and (iii) the over-time GAAP recognition of the Company’s receipt of HPL tokens. Adjusted EBITDA is used by management, in addition to GAAP financial measures, to understand and compare our operating results across accounting periods, for risk management and operational decision-making purposes. This non-GAAP measure provides investors with additional information in evaluating the Company's operating performance.

“Net Asset Value” is a non-GAAP measure. Net Asset Value is defined as the market value of our marketable digital assets less net outstanding debt. It is reconciled to the GAAP measure “HYPE digital assets” as adjusted to “Gross HYPE Holdings” (described more fully in Footnote 4) by (i) adding KNTQ digital assets and sKNTQ digital intangible assets at carrying value, (ii) adding HPL digital assets and sHPL digital intangible assets at carrying value, (iii) adding Hyperion Rysk Vault Shares at cost basis, (iv) adding Current Assets, (v) subtracting Current Liabilities (including current portion of Notes Payable, without subtracting corresponding debt discounts or any unamortized issuance expenses), and (vi) subtracting Notes Payable (Non-current portion, without subtracting corresponding debt discounts or any unamortized issuance expenses). We believe Net Asset Value is a helpful non-GAAP financial measure to our management and investors because it provides a more complete picture of our net liquid and marketable assets. It does not include Other digital intangible assets which may not be immediately marketable. It does not include other non-current assets or non-current liabilities beyond the aforementioned items. The Company believes Net Asset Value provides useful information about our balance sheet and financial performance, enhances the overall understanding of our past performance and future prospects, allows for greater transparency with respect to important metrics used by our management for financial, risk management and operational decision-making, and provides an additional tool for investors to use to understand and compare our operating results across accounting periods.

10.

Represents in-period accrued staking yield on HYPE LSTs. Staking yield on LSTs is not recognized in-period in accordance with GAAP; instead, LST staking yield may be recognized with an associated realized gain upon future reconversion from LSTs back into HYPE.

11.

Represents the estimated future financial implications if all company-owned LSTs were reconverted to HYPE at the end of each respective period. Encapsulates both the temporary GAAP valuation methodology differences between LSTs and HYPE plus the realization of previously accrued but unrecognized staking yield on LSTs.

12.

In the three months ended September 30, 2025, Gain on extinguishment of liability and a reduction in accrued liability within other income was approximately $2.2 million and $0.2 million respectively, combined totaling $2.4 million. In the three months ended March 31, 2026, gain on extinguishment of liabilities within Other income (expense), net totaled $0.2 million.

13.

In the reconciliation of “Total Other Income (Expense), Net” to “Adjusted Other Income (Expense)”, as well as in the reconciliation of “Net Income (Loss)” to “Adjusted EBITDA”, in the three months ended September 30, 2025, other non-recurring items include gains on sales of equipment, release of reserves held against potential returns of company-sold items, and a one-time realized payment in connection with a terminated LOI. In the three months ended December 31, 2025 and March 31, 2026, other non-recurring items include gains and losses due to valuation differences in the time between contractual and actual delivery dates on certain company-paid expenses denominated in HYPE and in Company equity.

14.

Estimated and unaudited figures as of May 11, 2026.

15.

Includes all net cash, cash equivalents, and USDH premiums received but unrealized on expired sold HYPE puts and calls, including within the Hyperion Rysk Vault, as well as third-party fees on yield enhancement activities (such third-party fees being included in DeFi Monetization within Non-GAAP Adjusted Gross Profit).

16.

Includes Hyperion Rysk Vault Shares, which are redeemable into USDH.

Exhibit 99.2

Hyperion DeFi © 2026 2 Use of Non-GAAP Financial Measures This presentation includes certain non-GAAP financial measures (including on a forward-looking basis) such as Adjusted Gross Profit, Gross HYPE Holdings, Net Asset Value, Operating Expenses Excluding Stock-Based Compensation, Treasury Gains (Losses), Adjusted Other Income (Expense), and Adjusted EBITDA. These non-GAAP measures are in addition to, and not a substitute for or superior to, measures of financial performance prepared in accordance with GAAP and should not be considered as an alternative to any performance measures derived in accordance with GAAP. Reconciliations of non-GAAP measures to their most directly comparable U.S. Generally Accepted Accounting Principles (GAAP) counterparts are included in the Financial Supplement - Non-GAAP Reconciliations section of this presentation with additional detail in the Footnotes. Hyperion DeFi believes that these non-GAAP measures of financial results (including on a forward-looking basis) provide useful supplemental information to investors about Hyperion DeFi. Hyperion DeFi’s management uses non-GAAP measures to evaluate our operating performance, formulate business plans, help better assess our overall liquidity position, and make strategic decisions, including those relating to operating expenses and the allocation of internal resources. However, these non-GAAP measures have limitations as analytical tools. Other companies may not use these non-GAAP measures or may use similar measures that are defined in a different manner. Therefore, Hyperion DeFi’s non-GAAP measures may not be directly comparable to similarly titled measures of other companies. We also periodically review our non-GAAP financial measures and may revise these measures to reflect changes in our business or otherwise. Additionally, forward-looking non-GAAP financial measures are presented on a non-GAAP basis without reconciliations of such forward-looking non-GAAP measures because the GAAP financial measures are not accessible on a forward-looking basis and reconciling information is not available without unreasonable effort due to the inherent difficulty in forecasting and quantifying certain amounts that are necessary for such reconciliations, including adjustments reflected in our reconciliation of historic non-GAAP financial measures, the amounts of which, based on historical experience, could be material. Forward-Looking Statements Except for historical information, all the statements, expectations and assumptions contained in this presentation are forward-looking statements. Forward-looking statements include, but are not limited to, statements that express our intentions, beliefs, expectations, strategies, predictions or any other statements, our future activities or other future events or conditions, including the estimated market opportunities for our platform technology, the viability of, and risks associated with, our cryptocurrency treasury strategy, and the growth and revenue potential of the Hyperliquid ecosystem and the growth prospects of Hyperion DeFi, Inc. (“Hyperion DeFi”, “Hyperion” or the “Company”) (NASDAQ:HYPD). These statements are based on current expectations, estimates and projections about our business based, in part, on assumptions made by management. These statements are not guarantees of future performance and involve risks, uncertainties and assumptions that are difficult to predict. Therefore, actual outcomes and results may, and in some cases are likely to, differ materially from what is expressed or forecasted in the forward-looking statements due to numerous factors discussed from time to time in documents which we file with the U.S. Securities and Exchange Commission (the “SEC”), including in particular, the risks of our cryptocurrency strategy as detailed in our reports filed with the SEC. Any forward-looking statements speak only as of the date on which they are made, and except as may be required under applicable securities laws, Hyperion DeFi does not undertake any obligation to update any forward-looking statements. Disclaimer Certain information contained in this presentation and statements made orally during the corresponding earnings call relate to or are based on studies, publications, surveys and other data obtained from third-party sources and Hyperion DeFi’s own internal estimates and research. While Hyperion DeFi believes these third-party studies, publications, surveys and other data to be reliable as of the date of this presentation, it has not independently verified, and makes no representation as to the adequacy, fairness, accuracy or completeness of, any information obtained from third-party sources. In addition, no independent source has evaluated the reasonableness or accuracy of Hyperion DeFi’s internal estimates or research and no reliance should be made on any information or statements made in this presentation relating to or based on such internal estimates and research. You should conduct your own investigation and analysis of Hyperion DeFi, its business, prospects, results of operations and financial condition. In furnishing this information, Hyperion DeFi does not undertake any obligation to provide you with access to any additional information (including forward-looking information and any projections contained herein) or to update or correct the information. All figures in this presentation are not audited. Throughout this document, totals may not sum due to rounding. Calculations are based on unrounded results. Figures in $ Q3 2025 Q4 2025 Q1 2026 Gross Profit 302,506 192,897 244,271 Adjusted Gross Profit(1) 439,386 820,997 959,568 HYPE Digital Assets 37,954,590 16,233,941 25,286,164 Gross HYPE Holdings(4) 77,751,604 47,837,901 71,037,344 Net Asset Value(9) 74,545,583 44,154,737 69,873,504 Selling, General and Administrative Expense 2,594,130 4,530,542 4,493,604 Operating Expenses Excluding Stock-Based Compensation(5) 4,315,016 3,007,135 2,975,883 Net Operating (Income) Expenses (4,125,685) 39,958,264 (8,487,848) Treasury Gains (Losses) (6) 11,868,872 (36,783,228) 21,451,862 Total Other Income (Expense), Net 2,197,391 (288) 108,431 Adjusted Other Income (Expense)(7) (42,240) 48,717 52,585 Net Income (Loss) 6,625,582 (39,765,565) 8,840,550 Adjusted EBITDA(8) 7,951,003 (38,920,649) 19,488,132

Hyperion DeFi © 2026 3 Achieved +17% quarter-over-quarter growth in our operating businesses (Adjusted Gross Profit(1)), driven by scaling DeFi Monetization and Yield Enhancement strategies (each at >100% q-o-q growth) HYPD Investment Thesis Note: Adjusted Gross Profit and Operating Expenses Excluding Stock-Based Compensation are non-GAAP financial measures. See “Footnotes” and "Financial Supplement" sections for detailed definitions and reconciliations to the nearest GAAP Metric. “Triple-Dip” HYPE deployment generated ~3.1x base staking income in Q1’26 versus ~2.7x in Q4’25 Strong earnings leverage with low cost base built for scale; achieved second sequential quarterly decline in core costs (Operating Expenses Excluding Stock-Based Compensation(5)) We are raising our guidance, and now anticipate $5M-$7M Adjusted Gross Profit(1) in 2026, ~5x our 2025 FY results Unique among digital asset treasuries with Five Diversified Operating Business Lines

Hyperion DeFi © 2026 4 Top 6 Hyperliquid Validator** Institutional Volatility Income Vault 24/7 On-Chain Partner Markets Secured On-Chain Lending Pools We are Building More Every Day Growing Hyperliquid Ecosystem Treasury(14) Ramping DeFi Business Lines Third Party Capabilities + + = Hyperion At A Glance +17% Q1 Q-o-Q Adjusted Gross Profit(1) Increased Guidance of $5M-$7M 2026 Adjusted Gross Profit(1) (~5x 2025) Unique “Triple-Dip” HYPE Deployment Across 5 Operating Strategies Achieved ~3.1x base staking income in Q1’26 versus ~2.7x in Q4’25 2.00M HYPE 1.92M KNTQ 10.0M HPL 1% of Issuance* The First Publicly Listed DeFi Company Building on Hyperliquid NASDAQ: HYPD More than just HYPE. *Silhouette is contractually obligated to award HYPD at least 1% of the total supply of any tokens generated in a future token generation event, or equity, including affiliates and related parties. **Excluding the Hyper Foundation, as of April 30, 2026. Note: Adjusted Gross Profit is non-GAAP financial measure. See “Footnotes” and "Financial Supplement" sections for detailed definitions and reconciliations to the nearest GAAP Metric.

Hyperion DeFi © 2026 5 Hyperion’s Differentiated Value Proposition vs. “Traditional DAT” $HYPE $HYPE Shareholder Value Tied to HODL + Ecosystem Engagement Income Shareholder Value Tied to HODL Multiple DEFI businesses Multiple DEFI businesses Traditional DAT HYPD Growth Over Ecosystem Time

Hyperion DeFi © 2026 6 HYPD is not simply a beta play on the price of HYPE Adjusted Gross Profit(1) has grown by +119% since Q3, and +17% sequentially versus Q4, from $439k in Q3, to $821k in Q4, to $960k thousand in Q1. Effective Average HYPE Price In-Period(3) declined from 45.8 in Q3, to 35.1 in Q4, to 30.8 Q1, in total a (33%) decline since Q3. Our Adjusted Gross Profit(1) multiple versus base staking yield grew from 1.3x in Q3, to 2.7x in Q4, to 3.1x in Q1, as our “triple-dip” HYPE strategy continues to demonstrate our unique execution advantage versus our peers. Effective Average HYPE Price In-Period(3) Adjusted Gross Profit (in $ thousands) (1) 45.8 439 35.1 821 30.8 960 HYPD Generates Independent, Scaling Businesses on Hyperliquid Q3’25 Q4’25 Q1’26

Hyperion DeFi © 2026 7 Five Diversified Operating Business Lines (In $ Thousands) Q3'25 Q4'25 Q1’26 QoQ Growth Ecosystem Rewards - 285 150 -47% DeFi Monetization <1 102 245 140% Yield Enhancement 78 79 211 165% Validator Commissions 21 49 40 -17% Staking Yield 340 305 313 2% Adjusted Gross Profit(1) 439 821 960 17% Multiple vs. Staking Yield 1.3x 2.7x 3.1x % Earned in Cash* 18% 22% 48% HYPE Earned in Staking & Validating(2) 7,895 10,076 11,458 14% Effective Average HYPE Price In-Period(3) 45.76 35.12 30.82 *The portion of Adjusted Gross Profit(1) earned in cash, cash equivalents, and USDH(16). Note: Adjusted Gross Profit is non-GAAP financial measure. See “Footnotes” and "Financial Supplement" sections for detailed definitions and reconciliations to the nearest GAAP Metric. 0 100,000 200,000 300,000 400,000 500,000 600,000 700,000 800,000 900,000 1,000,000 Q3'25 Q4'25 Q1'26 Adjusted Gross Profit(1) Staking Yield Validator Commissions Yield Enhancement DeFi Monetization Ecosystem Rewards

Hyperion DeFi © 2026 8 Increasing FY 2026 Guidance By +$1M Anticipate $5M-$7M Adjusted Gross Profit(1) in 2026, ~5x 2025 FY results Adjusted Gross Profit(1) Guidance Q3’25 Q4’25 FY’25 Q1’26 Q2’26 Q3’26 Q4’26 FY’26 Guidance 2026 Guidance vs. 2025 Actual Initial Guidance (Q4’25 A) $0.44M $0.82M $1.28M - - - - $4M - $6M ~4x Current Guidance (Q1’26 A) $0.44M $0.82M $1.28M $0.96M - - - $5M - $7M ~5x Increase +$1M Q1’26 vs. Q4’25 QoQ Adjusted Gross Profit(1) Growth (Actual): +17% Note: Adjusted Gross Profit is non-GAAP financial measure. See “Footnotes” and "Financial Supplement" sections for detailed definitions and reconciliations to the nearest GAAP Metric.

Hyperion DeFi © 2026 9 HYPD Treasury Over Time Note: Gross HYPE Holdings is non-GAAP financial measure. See “Footnotes” and "Financial Supplement" sections for detailed definitions and reconciliations to the nearest GAAP Metric. September 30, 2025 December 31, 2025 March 31, 2026 May 11, 2026(14) HYPD Net Basis(14) Gross HYPE Tokens(2) 1.72 M 1.88 M 1.94 M 2.00 M 2.00 M HYPE Token Price $45.2 $25.4 $36.6 $42.2 $37.9 Gross HYPE Holdings(4) $77.8 M $47.8 M $71.0 M $84.5 M $75.9 M Cash, Cash Equivalents, and USDH(16) $8.2 M $6.5 M $9.1 M $16.0 M

Hyperion DeFi © 2026 11 HYPD’s “Triple-Dip” HYPE Deployment is Possible Because of Our Management’s Unique Ability to Build on the Hyperliquid Blockchain HYPD DeFi Partner Deal Description DeFi Operating Activity Staking Yield Validator Commissions Yield Enhancement DeFi Monetization Ecosystem Rewards Kinetiq Hyperion x Kinetiq Validator Silhouette HYPE Asset Use Service (HAUS) Felix HAUS / HIP-3 Markets Native Markets USDH Aligned Stablecoin Kinetiq Markets kmHYPE / HIP-3 Markets Rysk Institutional Vaults HyperLend On-Chain Secured Lending 1 1 1 1 1 1 1 3 3 3 3 3 3 3 2 2 2 2 2 2 2 represent cumulative deployment of the same HYPE tokens into multiple strategies in each row 1 2 3

Hyperion DeFi © 2026 18 [ Why Hyperliquid (HYPE)? Top 1 revenue and Top 10 market cap cryptocurrency Source: CoinMarketCap Source: Artemis As April 30, 2026 As of April 30, 2026 Top Fees (24h) [ NAME 1 Bitcoin BTC 2 Ethereum ETH 3 XRP XRP 4 BNB BNB 5 Solana SOL 6 TRON TRX 7 Dogecoin DOGE 8 Hyperliquid HYPE 9 UNUS SED LEO LEO 10 Cardano ADA Market Cap: Top 10 Cryptocurrencies (excluding stablecoins) MARKET CAP $1,527,696,442,782 $273,167,181,158 $84,469,652,726 $82,886,426,938 $47,900,545,431 $30,870,919,551 $18,095,402,206 $9,956,177,530 $9,522,889,745 $8,894,343,415

Hyperion DeFi © 2026 19 TOKEN FIXED SUPPLY STAKING YIELD MARKET CAP** BUYBACKS Bitcoin $1,527,696,442,782 Ethereum $273,167,181,158 Solana $47,900,545,431 Hyperliquid $9,956,177,530 Hyperliquid’s Unique Token Design Hyperliquid generates an annualized revenue of >$725M+*. ~99% of this revenue goes back to daily buybacks of HYPE into the Assistance Fund, a powerful mechanism relative to its circulating market cap. Assistance Fund HYPE ~44M Assistance HYPE $ ~1.7B Source: Hypurrscan as of April 30, 2026 * As of April 30, 2026 based on annualized 30-day run rate per Defi Llama ** As of April 30, 2026; Source: CoinMarketCap

Hyperion DeFi © 2026 20 Hyperliquid’s (HYPE) Trading Platform Is Experiencing Rapid Adoption And Growth Hyperliquid Cryptocurrency Market Cap Ranking #8 Hyperliquid Market Cap ~$10.0 Billion Cumulative Fees Generated on Hyperliquid >$1.2 Billion Hyperliquid Circulating Token Supply ~255 Million Cumulative Hyperliquid Marketplace Users ~1.2 Million Hyperliquid Maximum Token Supply ~956 Million (~44 Million Burned) Hyperliquid Cryptocurrency Daily Revenue Ranking #1 Source: Hyperliquid Stats Source: Defi Llama Source: Defi Llama Source: CoinMarketCap; Hypurrscan Source: CoinMarketCap Source: CoinMarketCap Source: CoinMarketCap (Excluding Stablecoins) Source: Artemis As of April 30, 2026 Daily Trading Volume on Hyperliquid ~$8 Billion Cumulative Trading Volume on Hyperliquid >$4.3 Trillion Source: Defi Llama

Hyperion DeFi © 2026 21 Hyperliquid’s Parabolic Growth Hyperliquid has become the leading platform for on-chain derivatives, seen through its rapidly growing fees and crypto perpetuals (“perp”) trading volume expansion since its Token Genesis Event in November 2024. Source: Defi Llama Key Metrics Total Value Locked App Fees (24h) Crypto Spot Volume (24h) Perps Volume (24h) Open Interest $HYPE Price $HYPE Market Cap $HYPE Fully Diluted Value $6.9b $3.5m $173m $7.7b $7.8b $39.05 $9.96b $27.3b >$4.3 Trillion CUMULATIVE PERP VOLUME Hyperliquid (HYPE) As of April 30, 2026 >$1.2 Billion CUMULATIVE HYPERLIQUID FEES Source: Defi Llama

Hyperion DeFi © 2026 25 Early Mover Advantages Create Unique Opportunities for Compounding Revenue Streams Hyperliquid Staking Yield Validator Commissions Hyperliquid Staking Yield Hyperliquid Staking Yield Validator Commissions Yield Enhancement Validator Commissions Yield Enhancement Hyperliquid Staking Yield DeFi Monetization Validator Commissions Yield Enhancement Hyperliquid Staking Yield DeFi Monetization Ecosystem Rewards RETURNS HYPERION DEFI’S RAPIDLY COMPOUNDING DEFI STRATEGY Received 3M Foundation HYPE Delegation HAUS Felix Execution Co-Branded Kinetiq Validator Launched “HiHYPE” Liquid Staking Token Native Markets Partnership Rysk Yield Vaults HyperLend On-Chain Credit HAUS Silhouette Execution

Hyperion DeFi © 2026 26 Hyperion DeFi stakes and deploys HYPE into the Hyperliquid Ecosystem Clients unlock unique utility on Hyperliquid; Hyperion DeFi earns fees from Clients Client activity promotes broader Hyperliquid adoption Hyperion earns Validator Commissions and Ecosystem Rewards Hyperion DeFi reinvests revenues to purchase more HYPE How HYPD Drives the Institutional Adoption Flywheel • Reduced Trading Fees (Silhouette) • Launch of New “HIP3” Financial Markets (Felix) • On-chain credit pool (HyperLend) • On-chain yield vaults (Rysk) • Enable Native Markets’ USDH “Aligned Stablecoin” 1 2 3 4 5 • Eligible for KNTQ • Eligible for HPL • Eligible for Silhouette

Hyperion DeFi © 2026 28 Frictionless exposure to Hyperliquid’s native token HYPE. Access next-generation Decentralized Finance (DeFi). Bridging public markets and on-chain strategies. More than just HYPE. NASDAQ: HYPD

Hyperion DeFi © 2026 30 HYPD Non-GAAP Income Summary Note: Adjusted Gross Profit, Operating Expenses Excluding Stock-Based Compensation, Treasury Gains (Losses), Adjusted Other Income (Expense), and Adjusted EBITDA are non-GAAP financial measures. See “Footnotes” and "Financial Supplement" sections for detailed definitions and reconciliations to the nearest GAAP metric. (Figures in $) Q3 2025 Q4 2025 Q1 2026 Adjusted Gross Profit(1) 439,386 820,997 959,568 Operating Expenses Excluding Stock-Based Compensation(5) 4,315,016 3,007,135 2,975,883 Treasury Gains (Losses)(6) 11,868,872 (36,783,228) 21,451,862 Adjusted Other Income (Expense)(7) (42,240) 48,717 52,585 Adjusted EBITDA(8) 7,951,003 (38,920,649) 19,488,132

Hyperion DeFi © 2026 31 Description of Q1 2026 Digital Assets Operating Business Lines within Non-GAAP Adjusted Gross Profit(1) *Throughout this document, LST(s) is the abbreviation for “Liquid Staking Token(s)”, including HiHYPE (Hyperion Institutional HYPE), kHYPE (Kinetiq Staked HYPE), and kmHYPE (Kinetiq Market HYPE). Note: Adjusted Gross Profit is non-GAAP financial measure. See “Footnotes” and "Financial Supplement" sections for detailed definitions and reconciliations to the nearest GAAP Metric. Digital Assets Business Activity Description Ecosystem Rewards 10 million HPL tokens received from HyperLend in connection with the Company’s executed partnership agreements in March 2026, recorded on each end-of-day value when received. DeFi Monetization DeFi Monetization partnerships in connection with the Company’s temporary HYPE token use agreements plus third-party fees accrued in connection with yield enhancement activity. Yield Enhancement The Company’s first-party yield enhancement activity, including within the Hyperion Rysk Vault, and excluding third-party fees. Validator Commissions The Company’s portion of accrued net validator commissions from the Kinetiq x Hyperion Hyperliquid Validator, which are earned in HYPE and expressed as US dollars. Staking Yield The Company’s first-party Staking Yield on HYPE and HYPE LSTs* earned in HYPE and presented in US dollars.

Hyperion DeFi © 2026 32 Non-GAAP Financial Measures & Reconciliations Reconciliation of Adjusted Gross Profit(1) (unaudited) Note: See “Footnotes” section for detailed explanations and definitions. The sum of individual metrics may not always equal total amounts indicated due to rounding. For the Three Months Ended (Figures in $) September 30, 2025 December 31, 2025 March 31, 2026 Gross Profit 302,506 192,287 244,271 Add: Accumulated but unrealized staking yield on LSTs(10) 58,771 172,463 154,806 Add: Net gains on derivative instruments 78,109 79,461 39,401 Add: Accumulated but unrealized yield enhancement activity(15) - - 171,970 Add: Operating Income from airdrops - 285,450 - Add: Receipt of HPL tokens pursuant to partnership agreements - - 150,163 Add: Interest Income from DeFi Monetization activity - 90,636 198,957 Adjusted Gross Profit(1) 439,386 820,997 959,568

Hyperion DeFi © 2026 33 As of March 31, 2026 Value $ Token Count Token Price $ HYPE digital assets 25,286,164 690,505 36.62 Add: HYPE digital assets receivable* 11,071,201 302,327 36.62 HYPE digital intangible assets receivable** 9,230,486 250,000 36.62 HiHYPE at carrying value 7,785,852 378,277 20.58 kHYPE at carrying value 5,693,449 275,434 20.67 kmHYPE at carrying value 597,068 28,888 20.67 Unrealized accretion (dilution) expected upon future LST to HYPE Token Reconversion(11) 11,373,007 14,421 N.M. Gross HYPE Holdings(4) 71,037,344 Gross HYPE Tokens(2) 1,939,851 36.62 Unrealized accretion (dilution) expected upon LST to HYPE reconversion as of December 31, 2025 3,499,665 In-Period Change in unrealized accretion (dilution) expected upon LST to HYPE reconversion versus December 31, 2025 7,873,342 *Presented gross of $586,774 allowance for credit losses and $108,321 unamortized nonrefundable upfront fee. ** Presented gross of $323,067 allowance for credit losses. ***Throughout this document, N.M. is the abbreviation for "Not Meaningful“. Note: See “Footnotes” section for detailed explanations and definitions. The sum of individual metrics may not always equal total amounts indicated due to rounding. Non-GAAP Financial Measures & Reconciliations Q1’26 Reconciliation of Gross HYPE Holdings(4) (unaudited)

Hyperion DeFi © 2026 34 As of December 31, 2025 Value $ Token Count Token Price $ HYPE digital assets 16,233,941 638,352 25.43 Add: HYPE digital assets receivable* 7,647,740 300,725 25.43 HiHYPE at carrying value 8,437,277 398,277 21.18 kHYPE at carrying value 11,369,458 505,434 22.49 kmHYPE at carrying value 649,820 28,888 22.49 Unrealized accretion (dilution) expected upon future LST to HYPE Token Reconversion(11) 3,499,665 9,410 N.M. Gross HYPE Holdings(4) 47,837,901 Gross HYPE Tokens(2) 1,881,086 25.43 Unrealized accretion (dilution) expected upon LST to HYPE reconversion as of September 30, 2025 4,912,082 In-Period Change in unrealized accretion (dilution) expected upon LST to HYPE reconversion versus September 30, 2025 (1,412,417) *Presented gross of $405,331 allowance for credit losses and $307,278 unamortized nonrefundable upfront fee. Note: See “Footnotes” section for detailed explanations and definitions. The sum of individual metrics may not always equal total amounts indicated due to rounding. Non-GAAP Financial Measures & Reconciliations Q4’25 Reconciliation of Gross HYPE Holdings(4) (unaudited)

Hyperion DeFi © 2026 35 Non-GAAP Financial Measures & Reconciliations Q3’25 Reconciliation of Gross HYPE Holdings(4) (unaudited) *The Company did not hold any LSTs on or prior to June 30, 2025. Therefore, as of September 30, 2025, the in-period change in unrealized accretion (dilution) expected upon LST to HYPE Token Reconversion is the same as the absolute figure. Note: See “Footnotes” section for detailed explanations and definitions. The sum of individual metrics may not always equal total amounts indicated due to rounding. As of September 30, 2025 Value $ Token Count Token Price $ HYPE digital assets 37,954,590 839,889 45.19 Add: HiHYPE at Carrying Value 34,884,932 877,871 39.74 Unrealized accretion (dilution) expected upon future HiHYPE to HYPE Token Reconversion(11) 4,912,082 2,788 N.M. Gross HYPE Holdings(4) 77,751,604 Gross HYPE Tokens(2) 1,720,549 45.19 In-Period Change in unrealized accretion (dilution) expected upon LST to HYPE reconversion versus June 30, 2025* 4,912,082

Hyperion DeFi © 2026 36 Reconciliation of Operating Expense Excluding Stock-Based Compensation(5) For the Three Months Ended September 30, 2025 December 31, 2025 March 31, 2026 Value $ Value $ Value $ Selling, general and administrative expense 2,594,130 4,530,542 4,493,604 Subtract: stock-based compensation expense 1,347,031 (1,712,361) (1,804,485) Add: research and development expense 373,855 188,954 286,764 Operating Expense Excluding Stock-Based Compensation(5) 4,315,016 3,007,135 2,975,883 Non-GAAP Financial Measures & Reconciliations Reconciliation of Operating Expenses Excluding Stock-Based Compensation (5) (unaudited) & Disaggregated Stock-Based Compensation Note: See “Footnotes” section for detailed explanations and definitions. The sum of individual metrics may not always equal total amounts indicated due to rounding. Disaggregated Stock-Based Compensation For the Three Months Ended September 30, 2025 December 31, 2025 March 31, 2026 Value $ Value $ Value $ Mark-to-market adjustment of vested but undelivered stock-based compensation (2,140,000) - - Amortized expensing of unearned executive milestone awards 209,648 997,563 997,563 All remaining stock-based compensation 583,321 714,798 806,922 Total Stock-Based Compensation (1,347,031) 1,712,361 1,804,485

Hyperion DeFi © 2026 37 (Figures in $) For the Three Months Ended September 30, 2025 December 31, 2025 March 31, 2026 Net Operating (Expenses) Income 4,125,685 (39,958,264) 8,478,848 Add Back: Research and development expense 373,855 188,954 286,764 Selling, general and administrative expense 2,594,130 4,530,542 4,493,604 Provision for credit losses - 405,331 504,511 In-Period Change in unrealized accretion (dilution) upon LST to HYPE reconversion 4,912,082 (1,412,417) 7,873,342 Subtract: Accumulated but unrealized staking yield on LSTs(10) (58,771) (172,463) (154,806) Operating Income from airdrops - (285,450) - Net gains on derivative instruments (78,109) (79,461) (39,401) Treasury Gains (Losses)(6) 11,868,872 (36,783,228) 21,451,862 Non-GAAP Financial Measures & Reconciliations Reconciliation of Treasury Gains (Losses)(6) (unaudited) Note: See “Footnotes” section for detailed explanations and definitions. The sum of individual metrics may not always equal total amounts indicated due to rounding.

Hyperion DeFi © 2026 38 (Figures in $) For the Three Months Ended September 30, 2025 December 31, 2025 March 31, 2026 Total Other Income (Expense), Net 2,197,391 (288) 108,431 Add Back: Interest Expense 223,080 224,799 225,869 Reduction in life sciences liabilities(12) (2,407,154) - (225,173) Other non-recurring items(13) (55,557) (85,158) 142,415 Subtract: Interest Income from DeFi Monetization activity - (90,636) (198,957) Adjusted Other Income (Expense)(7) (42,240) 48,717 52,585 Non-GAAP Financial Measures & Reconciliations Reconciliation of Adjusted Other Income (Expense)(7) (unaudited) Note: See “Footnotes” section for detailed explanations and definitions. The sum of individual metrics may not always equal total amounts indicated due to rounding.

Hyperion DeFi © 2026 39 (Figures in $) For the Three Months Ended September 30, 2025 December 31, 2025 March 31, 2026 Net Income (Loss) 6,625,582 (39,765,565) 8,840,550 Add back: Stock-based compensation (1,347,031) 1,712,361 1,804,485 Interest expense 223,080 224,799 225,869 Provision for credit losses - 405,331 504,511 Income taxes - - - Depreciation and amortization expense* - - - Reductions in life sciences liabilities(12) (2,407,154) - (225,173) Other Non-Recurring Items(13) (55,557) (85,158) 142,415 Add: In-period change in unrealized accretion (dilution) expected upon LST to HYPE reconversion 4,912,082 (1,412,417) 7,873,342 Accumulated but unrealized yield enhancement activity(15) - - 171,970 Receipt of HPL tokens pursuant to partnership agreements - - 150,163 Adjusted EBITDA(8) 7,951,003 (38,920,649) 19,488,132 Non-GAAP Financial Measures & Reconciliations Reconciliation of Adjusted EBITDA(8) (unaudited) *Does not include Amortization of Operating Lease. Note: See “Footnotes” section for detailed explanations and definitions. The sum of individual metrics may not always equal total amounts indicated due to rounding.

Hyperion DeFi © 2026 40 (Figures in $) September 30, 2025 December 31, 2025 March 31, 2026 HYPE digital assets, as adjusted to Gross HYPE Holdings(4) 77,751,604 47,837,901 71,037,344 Add: KNTQ & sKNTQ at Carrying Value - 111,406 193,780 Add: HPL & sHPL at Carrying Value - - 149,820 Add: Hyperion Rysk Vault Shares at Cost Basis* - - 1,615,075 Add: Current Assets 9,085,767 7,245,809 8,803,947 Subtract: Current Liabilities** (4,037,092) (2,701,013) (4,509,992) Subtract: Notes Payable*** (8,254,696) (8,339,366) (7,416,353) Net Asset Value(9) 74,545,583 44,154,737 69,873,504 Non-GAAP Financial Measures & Reconciliations Reconciliation of Net Asset Value(9) (unaudited) *Digital intangible assets representing claims on USDH held in the Hyperion Rysk Institutional Volatility Income Vault, bearing the technical name “WHYPE-USDH-USDH-P-H-HL”. **Includes Notes payable - current portion as of March 31, 2026; does not subtract debt discount of $36,974 as of March 31, 2026. ***Non-current portion; does not subtract debt discount of $598,691 as of September 30, 2025, $543,230 as of December 31, 2025, or $450,796 as of March 31, 2026. Note: See “Footnotes” section for detailed explanations and definitions. The sum of individual metrics may not always equal total amounts indicated due to rounding.

Hyperion DeFi © 2026 42 Footnotes 1. “Adjusted Gross Profit” is a non-GAAP measure. Adjusted Gross Profit is defined as all in-period gross profit generated by the Company’s operations excluding buying digital assets and associated mark-to-market price movements. Such activities include staking yield, validator operations, yield enhancement activity, DeFi monetization partnerships, ecosystem rewards, and (prior to 2026) life sciences operations. It is reconciled to the GAAP measure “Gross Profit” by (i) adding accumulated but unrealized staking yield on LSTs, (ii) adding Net gains on derivative instruments, (iii) adding accumulated but unrealized yield enhancement activity as further described in Footnote 15, (iv) adding Operating Income from airdrops, (v) adding the Company’s receipt of HPL tokens pursuant to its partnership agreements with HyperLend, and (vi) adding the portion of GAAP “Interest Income” generated from digital assets receivables. We believe “Adjusted Gross Profit” is a helpful financial measure to our management and investors as it aims to capture all in-period gross profit generated by our active operational strategies without the impact of (i) the temporary GAAP earnings volatility of HYPE to LST conversion and LST to HYPE reconversion, (ii) the temporary GAAP earnings volatility of depositing and redeeming USDH versus Hyperion Rysk Vault Shares and delays in recognition of upfront received premium on expired sold HYPE put and call options, (iii) the over-time GAAP recognition of the Company’s receipt of HPL tokens, and (iv) dispersed GAAP presentment of our operational strategies across various Statements of Operations sections, or (iv) the impacts of realized or unrealized gains or losses on our digital assets. We believe Adjusted Gross Profit is a critical metric to quantify and compare our core operational activities between periods. In the Company’s earnings release and earnings supplement for three months ended September 30, 2025 and December 31, 2025, we previously reconciled Non-GAAP “Adjusted Gross Profit” to GAAP “Revenue”. Given changes in GAAP presentment related to staking and validating activities, we believe for the three months ended March 31, 2026, the closest comparable GAAP metric to Adjusted Gross Profit is Gross Profit. 2. The following are unaudited supplemental operating disclosures: Gross HYPE Tokens, the number of HYPE tokens staked at the Kinetiq x Hyperion Validator, Validator Commissions in HYPE, Staking Yield in HYPE, and HYPE Earned in Staking & Validating. 3. Calculated as the sum of the in-period Non-GAAP Adjusted Gross Profit components of (a) Validator Commissions plus (b) Staking Yield (such figures being expressed in-period in US Dollars), divided by the sum of (c) Validator Commissions in HYPE plus (d) Staking Yield in HYPE. 4. “Gross HYPE Holdings” is a non-GAAP measure. Gross HYPE Holdings is defined as the gross market value of the Company’s HYPE assuming (a) all temporary HYPE token use agreements are exited, (b) all collateralized OTC HYPE derivatives are exited (and such LST collateral returned to the Company), and (c) all LSTs were converted back to HYPE tokens as of the end of each respective reporting quarter. It is reconciled to the GAAP measure “HYPE digital assets” by adding (i) HYPE digital assets receivable (without subtracting allowance for credit loss or unamortized nonrefundable upfront fees), (ii) HYPE digital intangible assets receivable (without subtracting allowance for credit loss), (iii) HYPE LSTs at carrying value (including without limitation HiHYPE, kHYPE, and kmHYPE) and (iv) the unrealized accretion (dilution) expected upon LST to HYPE reconversion as of the end of each respective reporting quarter. We believe Gross HYPE Holdings is a helpful non-GAAP financial measure to our management and investors because it eliminates the temporary HYPE value impacts caused by our DeFi Monetization and Yield Enhancement token movements as well as the conversion and reconversion between HYPE tokens and LSTs, which (a) causes staking yield on our LSTs not to be recognized in-period in accordance with GAAP and (b) does not recognize upward mark-to-market movements in underlying HYPE tokens given LSTs are carried at the lower of cost basis or impaired value. As such, it provides useful information about our balance sheet, allows for greater transparency with respect to important metrics used by our management for financial, risk management and operational decision-making, and provides an additional tool for investors to understand and compare our operating results across reporting periods. 5. "Operating Expenses Excluding Stock-Based Compensation" is a non-GAAP measure. Operating Expenses Excluding Stock-Based Compensation is defined as the Company's operational expenses in-period excluding treasury value movements and stock-based compensation. It is reconciled to the GAAP measure “Selling, general and administrative expense” by (i) subtracting stock-based compensation expense and (ii) adding Research and development expense. Operating Expenses Excluding Stock-Based Compensation provides a metric of total operating expenditures in-period without the impact of treasury value movement or stock-based compensation, thereby creating a helpful metric for operational expense comparisons between different periods for our management and investors. 6. "Treasury Gains (Losses)" is a non-GAAP measure. Treasury Gains (Losses) is defined as the gross mark-to-market change in the company's digital asset treasury portfolio each period, without accounting for temporary GAAP impacts due to HYPE to LST conversion (or LST to HYPE reconversion) or operating income driven by airdrops or yield enhancement activity. It is reconciled to the GAAP measure “Net Operating Income (Expenses)" by (a) adding (i) Research and development expense, (ii) Selling, general, and administrative expense, (iii) Provision for credit losses, and (iv) the in-period change in unrealized accretion (dilution) expected upon LST to HYPE reconversion, and (b) subtracting (i) accumulated but unrealized staking yield on LSTs, (ii) Operating Income from airdrops, and (iii) Net gains on derivative instruments. Following these adjustments, Treasury Gains (Losses) is a singular metric that can present mark-to-market treasury changes in isolation, which we believe is a helpful metric for management and investors given our large digital asset treasury position and the volatile nature of digital assets. 7. "Adjusted Other Income (Expense)" is a non-GAAP measure. Adjusted Other Income (Expense) reflects management’s view of recurring activities outside of core operating income and operating expenses. It is reconciled to the GAAP measure "Total Other Income (Expense), Net" by (a) adding back (i) interest expense, (ii) non-recurring gains from reductions in life sciences liabilities, and (iii) other non-recurring items which we do not consider material in nature, and (b) subtracting the portion of GAAP “Interest Income” generated from digital assets receivables. The items added back to Adjusted Other Income (Expense) are excluded because they are non-cash in nature, or because the amount and timing of these items are unpredictable, are not driven by core results of operations, and render comparisons with prior periods and competitors less meaningful. The item subtracted from Adjusted Other Income (Expense) is already captured in the Non-GAAP metric “Adjusted Gross Profit”, as further described in Footnote 1. We believe Adjusted Other Income (Expense) provides a helpful view to management and investors regarding recurring and ongoing income and expense items outside of operating income and operating expenses, presented in a way to compare these elements over time.

Hyperion DeFi © 2026 43 Footnotes (continued) 8. “Adjusted EBITDA” is a non-GAAP measure. Adjusted EBITDA is meant to reflect management’s view of recurring business activities and a more comparable view of the mark-to-market impacts on our digital asset treasury holdings in-period. It is reconciled to the GAAP measure “Net Income (Loss)” by removing (i) stock-based compensation, (ii) interest expense, (iii) provision for credit losses, (iv) income taxes, (v) depreciation and amortization expense (excluding amortization of operating lease), (vi) non-recurring gains from reductions in life sciences liabilities, and (vii) other non-recurring items which we do not consider material in nature; and, it adds in (i) the in-period change in unrealized accretion (dilution) expected upon LST to HYPE reconversion, (ii) accumulated but unrealized yield enhancement activity as further described in Footnote 15, and (iii) the Company’s receipt of HPL tokens pursuant to its partnership agreements with HyperLend. The items excluded from our Adjusted EBITDA are excluded because they are non-cash in nature, or because the amount and timing of these items are unpredictable, are not driven by core results of operations, and render comparisons with prior periods and competitors less meaningful. The items added to Adjusted EBITDA are included to give a more complete picture of our in-period operations and mark-to-market impacts on our digital assets, disregarding (i) the temporary GAAP earnings volatility of HYPE to LST conversion and LST to HYPE reconversion, (ii) the temporary GAAP earnings volatility of depositing and redeeming USDH versus Hyperion Rysk Vault Shares and delays in recognition of upfront received premium on expired sold HYPE put and call options, and (iii) the over-time GAAP recognition of the Company’s receipt of HPL tokens. Adjusted EBITDA is used by management, in addition to GAAP financial measures, to understand and compare our operating results across accounting periods, for risk management and operational decision-making purposes. This non-GAAP measure provides investors with additional information in evaluating the Company's operating performance. 9. “Net Asset Value” is a non-GAAP measure. Net Asset Value is defined as the market value of our marketable digital assets less net outstanding debt. It is reconciled to the GAAP measure “HYPE digital assets” as adjusted to “Gross HYPE Holdings” (described more fully in Footnote 4) by (i) adding KNTQ digital assets and sKNTQ digital intangible assets at carrying value, (ii) adding HPL digital assets and sHPL digital intangible assets at carrying value, (iii) adding Hyperion Rysk Vault Shares at cost basis, (iv) adding Current Assets, (v) subtracting Current Liabilities (including current portion of Notes Payable, without subtracting corresponding debt discounts or any unamortized issuance expenses), and (vi) subtracting Notes Payable (Non-current portion, without subtracting corresponding debt discounts or any unamortized issuance expenses). We believe Net Asset Value is a helpful non-GAAP financial measure to our management and investors because it provides a more complete picture of our net liquid and marketable assets. It does not include Other digital intangible assets which may not be immediately marketable. It does not include other non-current assets or non-current liabilities beyond the aforementioned items. The Company believes Net Asset Value provides useful information about our balance sheet and financial performance, enhances the overall understanding of our past performance and future prospects, allows for greater transparency with respect to important metrics used by our management for financial, risk management and operational decision-making, and provides an additional tool for investors to use to understand and compare our operating results across accounting periods. 10. Represents in-period accrued staking yield on HYPE LSTs. Staking yield on LSTs is not recognized in-period in accordance with GAAP; instead, LST staking yield may be recognized with an associated realized gain upon future reconversion from LSTs back into HYPE. 11. Represents the estimated future financial implications if all company-owned LSTs were reconverted to HYPE at the end of each respective period. Encapsulates both the temporary GAAP valuation methodology differences between LSTs and HYPE plus the realization of previously accrued but unrecognized staking yield on LSTs. 12. In the three months ended September 30, 2025, Gain on extinguishment of liability and a reduction in accrued liability within other income was approximately $2.2 million and $0.2 million respectively, combined totaling $2.4 million. In the three months ended March 31, 2026, gain on extinguishment of liabilities within Other income (expense), net totaled $0.2 million. 13. In the reconciliation of “Total Other Income (Expense), Net” to “Adjusted Other Income (Expense)”, as well as in the reconciliation of “Net Income (Loss)” to “Adjusted EBITDA”, in the three months ended September 30, 2025, other non-recurring items include gains on sales of equipment, release of reserves held against potential returns of company-sold items, and a one-time realized payment in connection with a terminated LOI. In the three months ended December 31, 2025 and March 31, 2026, other non-recurring items include gains and losses due to valuation differences in the time between contractual and actual delivery dates on certain company-paid expenses denominated in HYPE and in Company equity. 14. Estimated and unaudited figures as of May 11, 2026. 15. Includes all net cash, cash equivalents, and USDH premiums received but unrealized on expired sold HYPE puts and calls, including within the Hyperion Rysk Vault, as well as third-party fees on yield enhancement activities (such third-party fees being included in DeFi Monetization within Non-GAAP Adjusted Gross Profit). 16. Includes Hyperion Rysk Vault Shares, which are redeemable into USDH.

Source: View Original Filing on SEC EDGAR

FAQ

How did Hyperion DeFi (HYPD) perform financially in Q1 2026?

Hyperion DeFi posted GAAP net income of $8.84 million in Q1 2026. Revenue was $244,271, and Adjusted EBITDA reached $19.49 million. This compares to a GAAP net loss of $3.48 million and much lower revenue of $14,720 in the same quarter of 2025.

What guidance did Hyperion DeFi (HYPD) provide for full-year 2026?

The company guided 2026 Adjusted Gross Profit to $5–$7 million. Management described this range as roughly five times 2025 levels, reflecting higher expected earnings from its DeFi operating segments beyond simple HYPE token holding and staking activities.

How large is Hyperion DeFi’s HYPE token treasury and Net Asset Value?

As of March 31, 2026, Gross HYPE Holdings totaled $71.04 million. Net Asset Value was $69.87 million, incorporating HYPE-related positions, other digital assets, current assets, and debt, giving investors a sense of the on-chain asset base supporting the business.

What does Hyperion DeFi’s Q1 2026 balance sheet look like?

Total assets were $70.07 million and stockholders’ equity was $58.49 million. Cash and cash equivalents were $7.38 million, with substantial digital assets and digital intangible assets, plus notes payable and lease liabilities making up the primary obligations.

Did Hyperion DeFi (HYPD) issue new shares in connection with this update?

Yes, the company issued 132,249 common shares under an underwriter option. This occurred on May 13, 2026 and generated approximately $0.4 million in net proceeds, representing a small capital raise relative to its existing equity base.

How fast is Hyperion DeFi growing its Adjusted Gross Profit?

Adjusted Gross Profit increased 17% quarter-over-quarter in Q1 2026. It rose from $821 thousand in Q4 2025 to $960 thousand in Q1 2026, highlighting continued scaling of DeFi operating activities beyond simple HYPE token price appreciation.

Filing Exhibits & Attachments

5 documents

Hyperion DeFi (HYPD) swings to Q1 2026 profit and raises DeFi earnings guidance

Rhea-AI Filing Summary

Positive

Negative

Insights

8-K Event Classification

Key Figures

Key Terms

Earnings Snapshot

FAQ

How did Hyperion DeFi (HYPD) perform financially in Q1 2026?

What guidance did Hyperion DeFi (HYPD) provide for full-year 2026?

How large is Hyperion DeFi’s HYPE token treasury and Net Asset Value?

What does Hyperion DeFi’s Q1 2026 balance sheet look like?

Did Hyperion DeFi (HYPD) issue new shares in connection with this update?

How fast is Hyperion DeFi growing its Adjusted Gross Profit?

Filing Exhibits & Attachments

Press Releases

Other Documents

Hyperion DeFi (HYPD) swings to Q1 2026 profit and raises DeFi earnings guidance

Rhea-AI Filing Summary

Positive

Negative

Insights

Crypto and equity analyst positive

8-K Event Classification

Key Figures

Key Terms

Earnings Snapshot

FAQ

How did Hyperion DeFi (HYPD) perform financially in Q1 2026?

What guidance did Hyperion DeFi (HYPD) provide for full-year 2026?

How large is Hyperion DeFi’s HYPE token treasury and Net Asset Value?

What does Hyperion DeFi’s Q1 2026 balance sheet look like?

Did Hyperion DeFi (HYPD) issue new shares in connection with this update?

How fast is Hyperion DeFi growing its Adjusted Gross Profit?

Filing Exhibits & Attachments

Press Releases

Other Documents