Hyperion DeFi CFO has 19,563 shares withheld for taxes

Rhea-AI Filing Summary

Hyperion DeFi, Inc. Chief Financial Officer David R. Knox had 19,563 shares of common stock withheld on September 29, 2026, to satisfy tax withholding obligations incurred upon vesting and settlement of part of a previously reported restricted stock unit grant. Following the withholding, he directly held 287,556 shares.

Insider Trade Summary

Tax Withholding: 19,563 shares

Tax Withholding 1 txn

Insider Knox David R.

Role Chief Financial Officer

Type	Security	Shares	Price	Value
Tax Withholding	Common Stock, par value $0.0001 F1	19,563	$0.00	$0.00

Holdings After Transaction: Common Stock, par value $0.0001 — 287,556 shares (Direct)

Footnotes (1)

1. F1. These shares were withheld to satisfy tax withholding obligations incurred upon the vesting and settlement of a portion of a previously reported grant of restricted stock units held by the Reporting Person

Key Figures

Shares withheld for tax liability: 19,563 shares Direct shares following transaction: 287,556 shares

2 metrics

Shares withheld for tax liability 19,563 shares September 29, 2026

Direct shares following transaction 287,556 shares Following the September 29, 2026 transaction

Key Terms

restricted stock units, tax withholding obligations, vesting, settlement

4 terms

restricted stock units financial

"a previously reported grant of restricted stock units"

Restricted stock units are a type of company reward where employees are promised shares of stock, but they only fully own these shares after meeting certain conditions, like staying with the company for a set time. They matter because they can become valuable assets and are often used to motivate employees to help the company succeed.

tax withholding obligations financial

"withheld to satisfy tax withholding obligations"

vesting financial

"upon the vesting and settlement"

Vesting is the process by which you earn full ownership of something, like company stock or a retirement benefit, over time. It’s like earning the right to keep a gift piece by piece the longer you stay with a company, making sure employees stay committed before they receive all the benefits.

settlement financial

"the vesting and settlement of a portion"

Settlement is the process of completing a financial transaction, like buying or selling a stock, by transferring money and ownership between parties. It ensures that both the buyer gets the asset and the seller gets paid, making the deal official. Without settlement, the transaction wouldn't be finalized or legally recognized.

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

How many shares did HYPD CFO David R. Knox have withheld?

19,563 shares of Hyperion DeFi, Inc. common stock were withheld on September 29, 2026, to satisfy tax withholding obligations arising from vesting and settlement of part of a previously reported restricted stock unit grant.

How many HYPD shares did David R. Knox hold after the withholding?

David R. Knox directly held 287,556 shares of Hyperion DeFi, Inc. common stock following the transaction reported for September 29, 2026.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Available on EDGAR 09/30/2026 - 05:00 PM Accepted by SEC EDGAR 09/30/2026 - 05:00 PM Learn about SEC filing dates

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Knox David R.

(Last) (First) (Middle)

C/O HYPERION DEFI, INC.

3090 NOWITZKI WAY, SUITE 300

(Street)

DALLAS TEXAS 75219

(City) (State) (Zip)

UNITED STATES

(Country)

2. Issuer Name and Ticker or Trading Symbol
HYPERION DEFI, INC. [ HYPD ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director		10% Owner
X	Officer (give title below)		Other (specify below)
	Chief Financial Officer

2a. Foreign Trading Symbol

3. Date of Earliest Transaction (Month/Day/Year)
09/29/2026

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock, par value $0.0001	09/29/2026		F		19,563(1)	D	$0	287,556	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

1. These shares were withheld to satisfy tax withholding obligations incurred upon the vesting and settlement of a portion of a previously reported grant of restricted stock units held by the Reporting Person

	/s/ David R. Knox	09/30/2026
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)