Immunome, Inc. reported that investment adviser Redmile Group, LLC and its principal Jeremy C. Green beneficially own 5,718,385 shares of Immunome common stock. This stake represents 5.2% of the outstanding common shares.
The shares are held by private investment funds managed by Redmile, with Redmile and Green having shared voting and shared dispositive power over all 5,718,385 shares and no sole voting or dispositive power. The percentage is calculated using 91,710,277 shares outstanding as of November 3, 2025, plus 18,625,000 shares issued and sold as of December 18, 2025.
Redmile and Green state that the securities were acquired and are held in the ordinary course of business and not for the purpose of changing or influencing control of Immunome. They each disclaim beneficial ownership beyond any pecuniary interest.
Positive
None.
Negative
None.
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
SCHEDULE 13G
UNDER THE SECURITIES EXCHANGE ACT OF 1934
(Amendment No. 3)
Immunome, Inc.
(Name of Issuer)
Common Stock, $0.0001 par value per share
(Title of Class of Securities)
45257U108
(CUSIP Number)
12/31/2025
(Date of Event Which Requires Filing of this Statement)
Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
Rule 13d-1(b)
Rule 13d-1(c)
Rule 13d-1(d)
SCHEDULE 13G
CUSIP No.
45257U108
1
Names of Reporting Persons
Redmile Group, LLC
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
DELAWARE
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
5,718,385.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
5,718,385.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
5,718,385.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
5.2 %
12
Type of Reporting Person (See Instructions)
IA, OO
Comment for Type of Reporting Person: Redmile Group, LLC's beneficial ownership of the Issuer's common stock ("Common Stock") is comprised of 5,718,385 shares of Common Stock owned by certain private investment vehicles managed by Redmile Group, LLC (the "Redmile Funds"). The reported securities may be deemed beneficially owned by Redmile Group, LLC as investment manager of the Redmile Funds. The reported securities may also be deemed beneficially owned by Jeremy C. Green as the principal of Redmile Group, LLC. Redmile Group, LLC and Mr. Green each disclaim beneficial ownership of these shares, except to the extent of its or his pecuniary interest in such shares, if any.
Percentage based on the sum of (i) 91,710,277 shares of Common Stock outstanding as of November 3, 2025, as reported by the Issuer in its Form 10-Q for the quarterly period ended September 30, 2025 filed with the SEC on November 6, 2025 (the "Form 10-Q"), plus (ii) 18,625,000 shares of Common Stock issued and sold as of December 18, 2025, as reported by the Issuer in its Form 8-K filed with the SEC on December 17, 2025 (the "Form 8-K").
SCHEDULE 13G
CUSIP No.
45257U108
1
Names of Reporting Persons
Jeremy C. Green
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
UNITED KINGDOM
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
5,718,385.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
5,718,385.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
5,718,385.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
5.2 %
12
Type of Reporting Person (See Instructions)
HC, IN
Comment for Type of Reporting Person: Jeremy C. Green's beneficial ownership of Common Stock is comprised of 5,718,385 shares of Common Stock owned by the Redmile Funds. The reported securities may be deemed beneficially owned by Redmile Group, LLC as investment manager of the Redmile Funds. The reported securities may also be deemed beneficially owned by Jeremy C. Green as the principal of Redmile Group, LLC. Redmile Group, LLC and Mr. Green each disclaim beneficial ownership of these shares, except to the extent of its or his pecuniary interest in such shares, if any.
Percentage based on the sum of (i) 91,710,277 shares of Common Stock outstanding as of November 3, 2025, as reported in the Form 10-Q, plus (ii) 18,625,000 shares of Common Stock issued and sold as of December 18, 2025, as reported in the Form 8-K.
SCHEDULE 13G
Item 1.
(a)
Name of issuer:
Immunome, Inc.
(b)
Address of issuer's principal executive offices:
18702 N. Creek Parkway, Suite 100, Bothell, WA 98011
Item 2.
(a)
Name of person filing:
Redmile Group, LLC
Jeremy C. Green
(b)
Address or principal business office or, if none, residence:
Redmile Group, LLC
One Letterman Drive
Building D, Suite D3-300
The Presidio of San Francisco
San Francisco, California 94129
Jeremy C. Green
c/o Redmile Group, LLC (NY Office)
45 W. 27th Street, Floor 11
New York, NY 10001
(c)
Citizenship:
Redmile Group, LLC: Delaware
Jeremy C. Green: United Kingdom
(d)
Title of class of securities:
Common Stock, $0.0001 par value per share
(e)
CUSIP No.:
45257U108
Item 3.
If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)
Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)
Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)
Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)
Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)
An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)
An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)
A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)
A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)
A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)
A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J),
please specify the type of institution:
(k)
Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.
Ownership
(a)
Amount beneficially owned:
Redmile Group, LLC - 5,718,385 (1)
Jeremy C. Green - 5,718,385 (1)
(b)
Percent of class:
Redmile Group, LLC - 5.2% (2)
Jeremy C. Green - 5.2% (2)
(c)
Number of shares as to which the person has:
(i) Sole power to vote or to direct the vote:
Redmile Group, LLC - 0
Jeremy C. Green - 0
(ii) Shared power to vote or to direct the vote:
Redmile Group, LLC - 5,718,385 (1)
Jeremy C. Green - 5,718,385 (1)
(iii) Sole power to dispose or to direct the disposition of:
Redmile Group, LLC - 0
Jeremy C. Green - 0
(iv) Shared power to dispose or to direct the disposition of:
Redmile Group, LLC - 5,718,385 (1)
Jeremy C. Green - 5,718,385 (1)
(1) Redmile Group, LLC's and Jeremy C. Green's beneficial ownership of the Issuer's Common Stock is comprised of 5,718,385 shares of Common Stock owned by the Redmile Funds. The reported securities may be deemed beneficially owned by Redmile Group, LLC as investment manager of the Redmile Funds. The reported securities may also be deemed beneficially owned by Jeremy C. Green as the principal of Redmile Group, LLC. Redmile Group, LLC and Mr. Green each disclaim beneficial ownership of these shares, except to the extent of its or his pecuniary interest in such shares, if any.
(2) Percentage based on the sum of (i) 91,710,277 shares of Common Stock outstanding as of November 3, 2025, as reported in the Form 10-Q, plus (ii) 18,625,000 shares of Common Stock issued and sold as of December 18, 2025, as reported in the Form 8-K.
Item 5.
Ownership of 5 Percent or Less of a Class.
Not Applicable
Item 6.
Ownership of more than 5 Percent on Behalf of Another Person.
Not Applicable
Item 7.
Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
If a parent holding company has filed this schedule, pursuant to Rule 13d-1(b)(ii)(G), so indicate under Item 3(g) and attach an exhibit stating the identity and the Item 3 classification of the relevant subsidiary. If a parent holding company has filed this schedule pursuant to Rule 13d-1(c) or Rule 13d-1(d), attach an exhibit stating the identification of the relevant subsidiary.
See the response to Item 4.
Item 8.
Identification and Classification of Members of the Group.
Not Applicable
Item 9.
Notice of Dissolution of Group.
Not Applicable
Item 10.
Certifications:
By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.
SIGNATURE
After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.
What ownership stake in Immunome (IMNM) does Redmile Group report?
Redmile Group and Jeremy C. Green report beneficial ownership of 5,718,385 Immunome common shares, representing 5.2% of the company’s outstanding stock. The position is held through private investment funds managed by Redmile, with shared voting and dispositive power over all reported shares.
How did Redmile Group calculate its 5.2% ownership in Immunome (IMNM)?
The 5.2% ownership is based on a total of 110,335,277 Immunome shares, combining 91,710,277 shares outstanding as of November 3, 2025 and 18,625,000 shares issued and sold as of December 18, 2025, as disclosed in Immunome’s Form 10-Q and Form 8-K.
Who holds the Immunome (IMNM) shares reported by Redmile Group?
The 5,718,385 Immunome shares are owned by certain private investment vehicles referred to as the Redmile Funds. Redmile Group, LLC serves as investment manager to these funds, and Jeremy C. Green is the principal of Redmile Group, giving them shared voting and dispositive power.
Does Redmile Group intend to influence control of Immunome (IMNM) with this stake?
Redmile Group and Jeremy C. Green certify the Immunome shares were acquired and are held in the ordinary course of business. They state the holdings are not for changing or influencing control of Immunome and are not part of any control-related transaction, aside from limited nomination activities.
What voting and dispositive powers do Redmile Group and Jeremy C. Green have over Immunome (IMNM) shares?
Redmile Group and Jeremy C. Green each report 0 shares with sole voting or dispositive power and 5,718,385 shares with shared voting and shared dispositive power. This means decisions over these Immunome shares are exercised jointly through their roles with the Redmile Funds.
Do Redmile Group and Jeremy C. Green fully accept beneficial ownership of their Immunome (IMNM) shares?
They state the securities may be deemed beneficially owned by Redmile Group and Jeremy C. Green due to their roles with the Redmile Funds. Both explicitly disclaim beneficial ownership of the Immunome shares, except to the extent of any pecuniary interest they may have.
