Immunome, Inc. Schedule 13G/A reports that Redmile Group, LLC and Jeremy C. Green each beneficially hold 5,558,885 shares of common stock, representing 4.9% of the class based on 113,133,199 shares outstanding as of February 27, 2026. The filing states these shares are owned by Redmile-managed investment vehicles and that both Redmile and Mr. Green disclaim direct beneficial ownership except for any pecuniary interest. The ownership figures are presented as of March 31, 2026 and the schedule is signed on May 15, 2026.
Positive
None.
Negative
None.
Insights
Board-level stake disclosure: Redmile and an associated principal report a 4.9% beneficial position.
Redmile Group, LLC and Jeremy C. Green disclose joint beneficial ownership of 5,558,885 shares, reported as held by Redmile-managed funds. The filing cites 113,133,199 shares outstanding as of February 27, 2026 as the denominator for the 4.9% figure.
The position is characterized as shared voting and dispositive power via investment vehicles; both parties include the standard disclaimer of direct ownership. Subsequent filings or 13D/13G amendments would show material shifts in passive/active intent or percentage thresholds.
Key Figures
Shares beneficially owned:5,558,885 sharesPercent of class:4.9%Shares outstanding (denominator):113,133,199 shares+2 more
5 metrics
Shares beneficially owned5,558,885 sharesRedmile-managed funds and Jeremy C. Green, as of March 31, 2026
Percent of class4.9%Based on 113,133,199 shares outstanding as of February 27, 2026
Shares outstanding (denominator)113,133,199 sharesAs reported in the Form 10-K for fiscal year ended December 31, 2025
Ownership reporting dateMarch 31, 2026Beneficial ownership stated as of this date in Item 4
Schedule execution dateMay 15, 2026Signature date on the Schedule 13G/A
Key Terms
Schedule 13G/A, Beneficially owned, Shared dispositive power
3 terms
Schedule 13G/Aregulatory
"Amendment No. 4 ) Immunome, Inc. Common Stock ..."
A Schedule 13G/A is an amended public filing with the U.S. securities regulator that updates a previous Schedule 13G, disclosing when an individual or group holds a substantial (typically over 5%) stake in a company and is claiming a passive, non‑controlling intent. Investors monitor these updates because rising or falling holdings can signal changing confidence, potential future moves, or shifts in voting power — like watching a public ledger where large shareholders quietly adjust their positions.
Beneficially ownedfinancial
"As of March 31, 2026, Redmile's and Jeremy C. Green's beneficial ownership ..."
Beneficially owned describes securities or assets where a person has the economic rights and control—such as the right to receive dividends and to direct voting—even if legal title is held in another name. Think of it like having the keys and using a car that’s registered to someone else: you get the benefits and make decisions. Investors care because beneficial ownership reveals who truly controls value and voting power, affecting corporate decisions and takeover dynamics.
Shared dispositive powerregulatory
"Shared Dispositive Power 5,558,885.00"
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
SCHEDULE 13G
UNDER THE SECURITIES EXCHANGE ACT OF 1934
(Amendment No. 4)
Immunome, Inc.
(Name of Issuer)
Common Stock, $0.0001 par value per share
(Title of Class of Securities)
45257U108
(CUSIP Number)
03/31/2026
(Date of Event Which Requires Filing of this Statement)
Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
Rule 13d-1(b)
Rule 13d-1(c)
Rule 13d-1(d)
schemaVersion:
SCHEDULE 13G
CUSIP Number(s):
45257U108
1
Names of Reporting Persons
Redmile Group, LLC
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
DELAWARE
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
5,558,885.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
5,558,885.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
5,558,885.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
4.9 %
12
Type of Reporting Person (See Instructions)
IA, OO
Comment for Type of Reporting Person: The information in Item 4 relating to the shares of the Issuer's common stock ("Common Stock") that are or may be deemed beneficially owned by Redmile Group, LLC ("Redmile") is incorporated herein by reference.
Percentage based on 113,133,199 shares of Common Stock outstanding as of February 27, 2026, as reported by the Issuer in its Form 10-K for the fiscal year ended December 31, 2025 filed with the SEC on March 3, 2026 (the "Form 10-K").
SCHEDULE 13G
CUSIP Number(s):
45257U108
1
Names of Reporting Persons
Jeremy C. Green
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
UNITED KINGDOM
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
5,558,885.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
5,558,885.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
5,558,885.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
4.9 %
12
Type of Reporting Person (See Instructions)
HC, IN
Comment for Type of Reporting Person: The information in Item 4 relating to the shares of Common Stock that are or may be deemed beneficially owned by Jeremy C. Green is incorporated herein by reference.
Percentage based on 113,133,199 shares of Common Stock outstanding as of February 27, 2026, as reported by the Issuer in the Form 10-K.
SCHEDULE 13G
Item 1.
(a)
Name of issuer:
Immunome, Inc.
(b)
Address of issuer's principal executive offices:
18702 N. Creek Parkway, Suite 100, Bothell, WA 98011
Item 2.
(a)
Name of person filing:
Redmile Group, LLC
Jeremy C. Green
(b)
Address or principal business office or, if none, residence:
Redmile Group, LLC
900 Larkspur Landing Circle, Suite 270
Larkspur, California 94939
Jeremy C. Green
c/o Redmile Group, LLC (NY Office)
45 W. 27th Street, Floor 11
New York, NY 10001
(c)
Citizenship:
Redmile Group, LLC: Delaware
Jeremy C. Green: United Kingdom
(d)
Title of class of securities:
Common Stock, $0.0001 par value per share
(e)
CUSIP No.:
45257U108
Item 3.
If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)
Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)
Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)
Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)
Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)
An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)
An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)
A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)
A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)
A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)
A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J),
please specify the type of institution:
(k)
Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.
Ownership
(a)
Amount beneficially owned:
Redmile Group, LLC - 5,558,885 (1)
Jeremy C. Green - 5,558,885 (1)
(b)
Percent of class:
Redmile Group, LLC - 4.9% (2)
Jeremy C. Green - 4.9% (2)
(c)
Number of shares as to which the person has:
(i) Sole power to vote or to direct the vote:
Redmile Group, LLC - 0
Jeremy C. Green - 0
(ii) Shared power to vote or to direct the vote:
Redmile Group, LLC - 5,558,885 (1)
Jeremy C. Green - 5,558,885 (1)
(iii) Sole power to dispose or to direct the disposition of:
Redmile Group, LLC - 0
Jeremy C. Green - 0
(iv) Shared power to dispose or to direct the disposition of:
Redmile Group, LLC - 5,558,885 (1)
Jeremy C. Green - 5,558,885 (1)
(1) As of March 31, 2026, Redmile's and Jeremy C. Green's beneficial ownership of Common Stock is comprised of 5,558,885 shares of Common Stock. All of such shares of Common Stock are directly owned by certain investment vehicles for which Redmile is the investment manager (the "Redmile Funds"). Redmile may be deemed to beneficially own these securities in its capacity as the investment manager with discretion to vote and dispose of all shares of Common Stock held by the Redmile Funds. Mr. Green also may be deemed to beneficially own these securities as the principal of Redmile. Redmile and Mr. Green each disclaim beneficial ownership of these securities, except to the extent of its or his pecuniary interest in such securities, if any.
(2) Percentage based on 113,133,199 shares of Common Stock outstanding as of February 27, 2026, as reported by the Issuer in the Form 10-K.
Item 5.
Ownership of 5 Percent or Less of a Class.
Ownership of 5 percent or less of a class
Item 6.
Ownership of more than 5 Percent on Behalf of Another Person.
Not Applicable
Item 7.
Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
If a parent holding company has filed this schedule, pursuant to Rule 13d-1(b)(ii)(G), so indicate under Item 3(g) and attach an exhibit stating the identity and the Item 3 classification of the relevant subsidiary. If a parent holding company has filed this schedule pursuant to Rule 13d-1(c) or Rule 13d-1(d), attach an exhibit stating the identification of the relevant subsidiary.
See the response to Item 4.
Item 8.
Identification and Classification of Members of the Group.
Not Applicable
Item 9.
Notice of Dissolution of Group.
Not Applicable
Item 10.
Certifications:
By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.
SIGNATURE
After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.
What stake does Redmile Group report in Immunome (IMNM)?
Redmile Group reports beneficial ownership of 5,558,885 shares, equal to 4.9% of the common stock using 113,133,199 shares outstanding as of February 27, 2026. The shares are held by Redmile-managed investment vehicles, per the schedule.
How is Jeremy C. Green connected to the holdings in IMNM?
Jeremy C. Green is reported as having shared voting and dispositive power over 5,558,885 shares, the same 4.9% position, because he is a principal of Redmile and may be deemed to beneficially own the shares through that role.
What date is used for the ownership percentage calculation?
The percentage is calculated using 113,133,199 shares outstanding as of February 27, 2026, a figure cited from Immunome's Form 10-K for the fiscal year ended December 31, 2025, referenced in the schedule.
What does the filing say about direct ownership versus manager control?
The filing states the shares are directly owned by investment vehicles managed by Redmile and that Redmile and Mr. Green disclaim direct beneficial ownership, while noting they have shared voting and dispositive power over the 5,558,885 shares.
When was the Schedule 13G/A signed and dated?
The schedule is executed and dated May 15, 2026, with the reported beneficial ownership position stated as of March 31, 2026 in the Item 4 disclosure.
