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Benjamin J. Zeskind reports beneficial ownership of 4,357,807 shares of Immuneering Corporation Class A common stock, representing 6.6% of the class. This ownership is calculated as of December 31, 2025, based on 64,569,967 shares outstanding as of November 5, 2025, as disclosed in Immuneering’s Form 10-Q. The position includes 2,312,852 shares held directly, 1,150,028 shares underlying stock options exercisable on or before March 1, 2026, and 894,927 shares held by the Benjamin J. Zeskind 2020 Family Trust, for which his spouse is sole trustee. Zeskind has sole voting and dispositive power over 3,462,880 shares and shared voting and dispositive power over 894,927 shares.
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
SCHEDULE 13G
UNDER THE SECURITIES EXCHANGE ACT OF 1934
(Amendment No. 4)
Immuneering Corporation
(Name of Issuer)
Class A common stock, par value $0.001 per share
(Title of Class of Securities)
45254E107
(CUSIP Number)
12/31/2025
(Date of Event Which Requires Filing of this Statement)
Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
Rule 13d-1(b)
Rule 13d-1(c)
Rule 13d-1(d)
SCHEDULE 13G
CUSIP No.
45254E107
1
Names of Reporting Persons
BENJAMIN J. ZESKIND
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
UNITED STATES
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
3,462,880.00
6
Shared Voting Power
894,927.00
7
Sole Dispositive Power
3,462,880.00
8
Shared Dispositive Power
894,927.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
4,357,807.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
6.6 %
12
Type of Reporting Person (See Instructions)
IN
SCHEDULE 13G
Item 1.
(a)
Name of issuer:
Immuneering Corporation
(b)
Address of issuer's principal executive offices:
245 MAIN STREET, SECOND FLOOR, CAMBRIDGE, MA, 02142
Item 2.
(a)
Name of person filing:
This statement is filed on behalf of Benjamin J. Zeskind (the "Reporting Person").
(b)
Address or principal business office or, if none, residence:
The principal business address of the Reporting Person is c/o Immuneering Corporation (the "Issuer"), 245 Main St., Second Floor, Cambridge, MA 02142.
(c)
Citizenship:
The Reporting Person is a citizen of the United States.
(d)
Title of class of securities:
Class A common stock, par value $0.001 per share
(e)
CUSIP No.:
45254E107
Item 3.
If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)
Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)
Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)
Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)
Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)
An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)
An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)
A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)
A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)
A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)
A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J),
please specify the type of institution:
(k)
Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.
Ownership
(a)
Amount beneficially owned:
4,357,807 (1)
(1) The ownership information presented herein represents the Reporting Person's beneficial ownership of shares of the Issuer's Class A common stock, par value $0.001 per share ("Class A Common Stock") as of December 31, 2025 and is based upon 64,569,967 shares of the Issuer's Class A Common Stock outstanding as of November 5, 2025, as disclosed in the Issuer's Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on November 12, 2025. The Reporting Person is the beneficial owner of 4,357,807 shares of the Issuer's Class A Common Stock, which consists of: (i) 2,312,852 shares of Class A Common Stock held of record by the Reporting Person; (ii) 1,150,028 shares of Class A Common Stock underlying stock options held of record by the Reporting Person that are exercisable on or prior to March 1, 2026; and (iii) 894,927 shares of Class A Common Stock held of record by the Benjamin J. Zeskind 2020 Family Trust, of which the Reporting Person's spouse serves as sole trustee.
(b)
Percent of class:
6.6 %
(c)
Number of shares as to which the person has:
(i) Sole power to vote or to direct the vote:
3,462,880
(ii) Shared power to vote or to direct the vote:
894,927
(iii) Sole power to dispose or to direct the disposition of:
3,462,880
(iv) Shared power to dispose or to direct the disposition of:
894,927
Item 5.
Ownership of 5 Percent or Less of a Class.
Not Applicable
Item 6.
Ownership of more than 5 Percent on Behalf of Another Person.
Not Applicable
Item 7.
Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
Not Applicable
Item 8.
Identification and Classification of Members of the Group.
Not Applicable
Item 9.
Notice of Dissolution of Group.
Not Applicable
Item 10.
Certifications:
Not Applicable
SIGNATURE
After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.
