Abigail P. Johnson and FMR Report 14.5% Stake in Immuneering (IMRX)

Rhea-AI Filing Summary

FMR LLC and Abigail P. Johnson reported beneficial ownership of 8,787,052 shares of Immuneering Corp Class A common stock, representing 14.5% of the class as of 09/30/2025. The filing shows FMR LLC holds 8,780,283 shares with sole voting power and 8,787,052 shares with sole dispositive power, while Abigail P. Johnson is reported with sole dispositive power for the same 8,787,052 shares.

The filing discloses that the Fidelity Growth Company Commingled Pool held 3,317,460 shares, or 5.5% of the class, at the same date. Signatures attest the holdings were acquired in the ordinary course of business and not for the purpose of changing control.

Positive

• Material stake disclosed: 8,787,052 shares represent 14.5% of Class A stock
• Clear voting/dispositive details: FMR LLC reports sole voting power on 8,780,283 shares and sole dispositive power on 8,787,052
• Transparency on pooled holdings: Fidelity Growth Company Pool holds 3,317,460 shares (5.5%)

Negative

• None.

Insights

Institutional Ownership Analyst

Large passive stake: 8.79M shares (14.5%) signals meaningful institutional exposure.

The reported 8,787,052 shares equal 14.5% of Class A stock, a concentration that can affect liquidity and shareholder composition.

Dependencies include whether holdings are passive or part of actively managed sleeves; the filing states the position is held in the ordinary course of business. Monitor quarterly filings for changes within one quarter to one year.

Corporate Governance Analyst

Beneficial ownership by a voting-control capable entity and an individual requires governance monitoring.

The cover page shows FMR LLC with sole voting power for 8,780,283 shares and Abigail P. Johnson with sole dispositive power for 8,787,052 shares; both report the same aggregate stake of 14.5%.

Watch for any related-party actions or changes in voting intent disclosed in future filings over the next few quarters; the filing affirms no current intent to change control.

SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13G

UNDER THE SECURITIES EXCHANGE ACT OF 1934

IMMUNEERING CORP

(Name of Issuer)

Class A Common Stock

(Title of Class of Securities)

45254E107

(CUSIP Number)

09/30/2025

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

Rule 13d-1(b)

Rule 13d-1(c)

Rule 13d-1(d)

SCHEDULE 13G

CUSIP No. 45254E107

1

Names of Reporting Persons

FMR LLC

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 8,780,283.00
6	Shared Voting Power 0.00
7	Sole Dispositive Power 8,787,052.00
8	Shared Dispositive Power 0.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

8,787,052.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

14.5 %

12

Type of Reporting Person (See Instructions)

HC

SCHEDULE 13G

CUSIP No. 45254E107

1

Names of Reporting Persons

Abigail P. Johnson

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

UNITED STATES

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 0.00
7	Sole Dispositive Power 8,787,052.00
8	Shared Dispositive Power 0.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

8,787,052.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

14.5 %

12

Type of Reporting Person (See Instructions)

IN

SCHEDULE 13G

Item 1.
(a)	Name of issuer: IMMUNEERING CORP
(b)	Address of issuer's principal executive offices: 245 MAIN STREET,SECOND FLOOR,CAMBRIDGE,MA,USA,02142
Item 2.
(a)	Name of person filing: FMR LLC
(b)	Address or principal business office or, if none, residence: 245 Summer Street, Boston, Massachusetts 02210
(c)	Citizenship: Not applicable
(d)	Title of class of securities: Class A Common Stock
(e)	CUSIP No.: 45254E107
Item 3.	If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)	Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)	Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)	Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)	Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)	An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)	An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)	A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)	A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)	A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)	A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J), please specify the type of institution:
(k)	Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.	Ownership
(a)	Amount beneficially owned: 8787052.00
(b)	Percent of class: 14.5 %
(c)	Number of shares as to which the person has:
	(i) Sole power to vote or to direct the vote: Please see the responses to Items 5 and 6 on the cover page.
	(ii) Shared power to vote or to direct the vote: 0.00
	(iii) Sole power to dispose or to direct the disposition of: 8787052.00
	(iv) Shared power to dispose or to direct the disposition of: 0.00
Item 5.	Ownership of 5 Percent or Less of a Class.
Item 6.	Ownership of more than 5 Percent on Behalf of Another Person.
	If any other person is known to have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, such securities, a statement to that effect should be included in response to this item and, if such interest relates to more than 5 percent of the class, such person should be identified. A listing of the shareholders of an investment company registered under the Investment Company Act of 1940 or the beneficiaries of employee benefit plan, pension fund or endowment fund is not required. One or more other persons are known to have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, the Class A Common Stock of IMMUNEERING CORP. The interest of Fidelity Growth Company Commingled Pool, in the Class A Common Stock of IMMUNEERING CORP, amounted to 3317460.00 shares or 5.5% of the total outstanding Class A Common Stock at 09/30/2025.
Item 7.	Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
	If a parent holding company has filed this schedule, pursuant to Rule 13d-1(b)(ii)(G), so indicate under Item 3(g) and attach an exhibit stating the identity and the Item 3 classification of the relevant subsidiary. If a parent holding company has filed this schedule pursuant to Rule 13d-1(c) or Rule 13d-1(d), attach an exhibit stating the identification of the relevant subsidiary. See attached Exhibit 99.
Item 8.	Identification and Classification of Members of the Group.
	Not Applicable
Item 9.	Notice of Dissolution of Group.
	Not Applicable

Item 10.

Certifications:

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

FMR LLC

Signature:	Stephanie J. Brown
Name/Title:	Duly authorized under Power of Attorney effective as of January 3, 2023, by and on behalf of FMR LLC and its direct and indirect subsidiaries*
Date:	10/06/2025

Abigail P. Johnson

Signature:	Stephanie J. Brown
Name/Title:	Duly authorized under Power of Attorney effective as of January 26, 2023, by and on behalf of Abigail P. Johnson**
Date:	10/06/2025

Comments accompanying signature: * This power of attorney is incorporated herein by reference to Exhibit 24 to the Schedule 13G filed by FMR LLC on January 10, 2023, accession number: 0000315066-23-000003. ** This power of attorney is incorporated herein by reference to Exhibit 24 to the Schedule 13G filed by FMR LLC on January 31, 2023, accession number: 0000315066-23-000038.

Exhibit Information

Please see Exhibit 99 for 13d-1(k) (1) agreement.

FAQ

What stake did FMR LLC and Abigail P. Johnson report in IMRX?

They reported beneficial ownership of 8,787,052 shares, equal to 14.5% of Class A common stock as of 09/30/2025.

How many shares does FMR LLC have voting power over in IMRX?

FMR LLC reports sole voting power over 8,780,283 shares and sole dispositive power over 8,787,052 shares.

Does Abigail P. Johnson hold voting power for the reported IMRX shares?

The filing shows Abigail P. Johnson with 0 sole voting power but with sole dispositive power over 8,787,052 shares.

Did the filing say the holdings aim to change company control?

No; the certification states the securities were acquired and are held in the ordinary course of business and not to change or influence control.

What portion of IMRX did the Fidelity Growth Company Pool own?

The Fidelity Growth Company Commingled Pool owned 3,317,460 shares, or 5.5% of Class A common stock at 09/30/2025.