Welcome to our dedicated page for Inhibrx Biosciences SEC filings (Ticker: INBX), a comprehensive resource for investors and traders seeking official regulatory documents including 10-K annual reports, 10-Q quarterly earnings, 8-K material events, and insider trading forms.
Inhibrx Biosciences, Inc. filings document the regulatory record of a clinical-stage biopharmaceutical company with two principal clinical programs, ozekibart (INBRX-109) and INBRX-106. Form 8-K reports furnish financial results, Regulation FD presentations, and clinical updates covering oncology studies in chondrosarcoma, colorectal cancer, Ewing sarcoma, head and neck squamous cell carcinoma, and non-small cell lung cancer.
The company’s proxy materials describe annual meeting matters, board elections, executive compensation and equity incentive governance. Its filings also identify Inhibrx Biosciences as an emerging growth company and provide formal disclosures on operating results, pipeline development, capital resources, risk factors, and the completed 2024 separation from Inhibrx, Inc.
Inhibrx Biosciences, Inc. received an updated Schedule 13G/A showing that investment entities affiliated with Viking Global Investors collectively report beneficial ownership of 1,454,608 shares of common stock, or 9.99% of the company. This includes shares held by Viking Global Opportunities Illiquid Investments Sub-Master LP, KAVRA 104 LLC and Viking Global Opportunities Drawdown (Aggregator) LP, plus 16,903 shares that VGOP may acquire through low‑priced warrants.
The ownership percentages are calculated using 14,543,738 shares outstanding as of November 7, 2025 and the currently exercisable warrant shares. All reporting persons disclose shared, and no sole, voting and dispositive power over their positions. They also certify that the securities are not held for the purpose of changing or influencing control of Inhibrx Biosciences.
Morgan Stanley and its affiliate Morgan Stanley Capital Services LLC have filed a Schedule 13G reporting beneficial ownership of Inhibrx Biosciences, Inc. common stock as of 12/31/2025. Morgan Stanley reports beneficial ownership of 1,155,416 shares, representing 7.9% of the outstanding common stock.
Morgan Stanley Capital Services LLC reports beneficial ownership of 918,011 shares, or 6.3% of the class, with shared voting and dispositive power over those shares. The securities are certified as acquired and held in the ordinary course of business, not for the purpose of changing or influencing control of Inhibrx Biosciences.
BlackRock, Inc. has filed a Schedule 13G reporting a passive ownership stake in Inhibrx Biosciences, Inc. common stock. BlackRock reports beneficial ownership of 768,130 shares, representing 5.3% of the company’s outstanding common stock as of the event date. BlackRock has sole voting power over 759,521 shares and sole dispositive power over 768,130 shares, with no shared voting or dispositive power.
The filing states that these securities are held in the ordinary course of business and are not held for the purpose of changing or influencing control of Inhibrx Biosciences. Various underlying clients or investors have rights to dividends or sale proceeds, but no single underlying holder has more than 5% of the total outstanding common shares.
Inhibrx Biosciences, Inc. reported clinical development updates for its immuno‑oncology programs INBRX‑106 and ozekibart. For INBRX‑106, it has enrolled 46 of 60 patients in the randomized Phase 2 portion of a Phase 2/3 trial in combination with Keytruda as a first‑line treatment for unresectable or metastatic head and neck squamous cell carcinoma, with completion of Phase 2 enrollment expected in the first quarter of 2026. A separate Phase 1/2 cohort of 34 patients with checkpoint inhibitor refractory or relapsed non‑small cell lung cancer in combination with Keytruda has completed enrollment.
Current datasets for both head and neck cancer and lung cancer are not yet mature enough to draw conclusions, and Inhibrx expects data in the second half of 2026 to assess the viability of INBRX‑106 in combination with Keytruda. For ozekibart, Inhibrx has completed enrollment of 44 patients in a Phase 1/2 expansion cohort in advanced colorectal cancer, with progression‑free survival data expected to mature in the second quarter of 2026, and it aims to complete enrollment in an Ewing sarcoma trial in the second quarter of 2026 and then discuss a potential accelerated approval pathway with the FDA in the second half of 2026 if current response trends continue.
Inhibrx Biosciences furnished an 8-K to announce it issued a press release with financial results for the three and nine months ended September 30, 2025. The press release is provided as Exhibit 99.1.
The company states the information under Item 2.02, including Exhibit 99.1, is being furnished and not deemed filed under the Exchange Act, and will not carry Section 18 liability or be incorporated by reference unless expressly specified.
The filing also includes Exhibit 104, the cover page interactive data file embedded in Inline XBRL.
Inhibrx Biosciences (INBX) filed its Q3 2025 report, showing steady cash and ongoing investment in its pipeline. Cash and cash equivalents were $153.1 million as of September 30, 2025, with management stating this should fund operations for at least 12 months. The company reported a net loss of $35.3 million for the quarter and $107.2 million year to date. Year‑to‑date revenue was $1.3 million from a Scithera license.
Operating expenses decreased versus the prior year period, with research and development at $87.7 million year to date (vs. $170.4 million in 2024) and general and administrative at $17.7 million (vs. $111.2 million in 2024, which included merger-related items). Long‑term debt was $99.9 million, reflecting the $100.0 million term loan entered on January 13, 2025; interest expense was $9.0 million year to date.
The pipeline advanced: ozekibart (INBRX‑109) met its Phase 2 primary endpoint in chondrosarcoma, more than doubling median PFS to 5.52 months versus 2.66 months for placebo (hazard ratio 0.479; P<0.0001). Shares outstanding were 14,498,093 as of September 30, 2025.
Inhibrx Biosciences (INBX) reported positive topline results from its registrational ChonDRAgon study (n=206) of ozekibart (INBRX-109) in advanced or metastatic, unresectable chondrosarcoma. The trial met its primary endpoint, showing a 52% reduction in risk of progression or death versus placebo (HR 0.479; P<0.0001) and more than doubling median progression-free survival to 5.52 months vs 2.66 months. Disease control rate was 54% vs 27.5%, with consistent benefit across IDH subgroups.
Safety was generally manageable; common events included fatigue, constipation, and nausea. Hepatotoxicity risk was addressed via exclusion of severe hepatic impairment and early-cycle monitoring; treatment-related hepatic adverse events occurred in 11.8% vs 4.5% on placebo.
In expansion cohorts, ozekibart plus FOLFIRI in late-line colorectal cancer showed 23% ORR and 92% disease control (26 evaluable). In refractory Ewing sarcoma with IRI/TMZ, ORR was 64% and disease control 92% (25 evaluable). Inhibrx plans a BLA submission in Q2 2026 and will present detailed data on November 14, 2025 at CTOS.
Viking Global and affiliated entities reported multiple sales of Inhibrx Biosciences, Inc. (INBX) common stock executed on 10/07/2025 at a price of $32.25 per share. The largest single reported sale was 308,643 shares, plus additional sales of 25,042 and 16,315 shares, reducing reported holdings across the reporting group to 1,267,823, 102,864 and 67,018 shares respectively depending on the specific vehicle or account. The filing lists multiple related reporting persons and entities that may be deemed to beneficially own the shares through fund and GP relationships, and includes the standard disclaimer limiting beneficial ownership claims to pecuniary interest. The Form 4 is a joint filing signed by Scott M. Hendler on behalf of the reporting persons.
Inhibrx Biosciences, Inc. furnished a press release announcing its financial results for the three and six months ended June 30, 2025. The press release is furnished as Exhibit 99.1 to this Current Report and an interactive XBRL cover page is included as Exhibit 104.
The company states the information in Item 2.02, including Exhibit 99.1, is furnished and not deemed "filed" for purposes of Section 18 of the Exchange Act, so it is subject to different legal treatment than filed disclosures. The report confirms Inhibrx's Nasdaq listing under the ticker INBX and indicates the registrant is an emerging growth company.
Inhibrx Biosciences reported a materially different quarter versus the prior-year period driven by the post‑spin financial position and new financing. Revenue was $1.3 million for the quarter from a Scithera license, while operating expenses were $28.7 million leading to an operating loss of $27.4 million and a net loss of $28.654 million for the three months ended June 30, 2025. The prior-year period included a $2.02 billion gain related to the Merger with the Former Parent, which produced the large net income figure in 2024.
The balance sheet shows $186.6 million cash and equivalents and total assets of $212.1 million, with accumulated deficit of $178.1 million. The company established long-term debt under a 2025 Loan Agreement with Oxford resulting in long-term debt, net of discount, of $99.3 million. Management states existing cash is sufficient to fund operations for at least 12 months. Clinically, the company continues development of ozekibart (INBRX-109) and INBRX-106, and completed full enrollment in its registration‑enabling chondrosarcoma trial in July 2025.