[SCHEDULE 13G/A] InfuSystem Holdings, Inc. SEC Filing

Rhea-AI Filing Summary

AWM Investment Company, Inc. filed an amendment to Schedule 13G reporting beneficial ownership of 1,272,296 shares of InfuSystem Holdings, Inc. common stock, representing 6.1% of the outstanding class. AWM states it is the investment adviser to Special Situations Life Sciences Fund, L.P. (SSLS) and holds sole voting and sole dispositive power over the shares held by SSLS. The filing discloses Delaware organization for AWM, the issuer's principal office in Rochester Hills, Michigan, and confirms the stake was acquired and is held in the ordinary course of business, not for the purpose of changing control.

Positive

• Material disclosure: Reports a >5% position (1,272,296 shares), meeting SEC transparency requirements
• Sole voting and dispositive power: AWM explicitly holds exclusive authority over the shares held by SSLS
• Certification included: States shares are held in the ordinary course and not to change or influence control

Negative

• None.

Insights

Financial Analyst

TL;DR: Disclosure shows a >5% position with sole voting/dispositive power via an adviser relationship, a routine but materially reportable stake.

AWM reports a 6.1% ownership position (1,272,296 shares) in INFU held through SSLS, where AWM has exclusive authority to vote and dispose of the shares. For investors, the filing signals an institutional-sized stake that must be monitored for any future schedule amendments or changes in intent. The certification clarifies the position is held in the ordinary course, reducing immediate governance-change concerns.

Corporate Governance Expert

TL;DR: The filing documents adviser control of a meaningful stake but disclaims intent to influence control; governance implications are currently limited.

A 6.1% disclosure triggers reporting obligations and gives AWM/SSLS a visible stake in INFU, with sole voting authority reported. The explicit certification that the stake is not held to change control is important legally; however, any future coordination between the adviser and the fund's GP could change disclosure or proxy dynamics, so subsequent filings would be decisive.

SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13G

UNDER THE SECURITIES EXCHANGE ACT OF 1934

(Amendment No. 10)

InfuSystem Holdings, Inc

(Name of Issuer)

Common Stock

(Title of Class of Securities)

45685K102

(CUSIP Number)

06/30/2025

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

Rule 13d-1(b)

Rule 13d-1(c)

Rule 13d-1(d)

SCHEDULE 13G

CUSIP No. 45685K102

1

Names of Reporting Persons

AWM Investment Company, Inc.

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 1,272,296.00
6	Shared Voting Power 0.00
7	Sole Dispositive Power 1,272,296.00
8	Shared Dispositive Power 0.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

1,272,296.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

6.1 %

12

Type of Reporting Person (See Instructions)

IA

Comment for Type of Reporting Person: AWM Investment Company, Inc., a Delaware corporation (AWM), is the investment adviser to Special Situations Life Sciences Fund, L.P. (SSLS) (SSLS will hereafter be referred to as the Fund). As the investment adviser to the Fund, AWM holds sole voting and investment power over 1,272,296 Shares held by SSLS.

SCHEDULE 13G

Item 1.
(a)	Name of issuer: InfuSystem Holdings, Inc
(b)	Address of issuer's principal executive offices: 3851 WEST HAMLIN ROAD, ROCHESTER HILLS, MICHIGAN, 48309
Item 2.
(a)	Name of person filing: The person filing this report is AWM Investment Company, Inc., a Delaware corporation (AWM), which is the investment adviser to Special Situations Life Sciences Fund, L.P. a Delaware limited partnership (SSLS), (SSLS, will hereafter be referred to as the Fund). The principal business of the Fund is to invest in equity and equity-related securities and other securities of any kind or nature. David M. Greenhouse (Greenhouse) and Adam C. Stettner (Stettner) are members of LS Advisers, L.LC., a New York limited liability company (LS). Greenhouse and Stettner are also controlling principals of AWM.
(b)	Address or principal business office or, if none, residence: The principal business address for AWM is c/o Special Situations Funds, 527 Madison Avenue, Suite 2600, New York, NY 10022.
(c)	Citizenship: AWM is a Delaware Corporation
(d)	Title of class of securities: Common Stock
(e)	CUSIP No.: 45685K102
Item 3.	If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)	Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)	Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)	Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)	Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)	An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)	An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)	A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)	A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)	A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)	A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J), please specify the type of institution:
(k)	Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.	Ownership
(a)	Amount beneficially owned: 1,272,296
(b)	Percent of class: 6.1 %
(c)	Number of shares as to which the person has:
	(i) Sole power to vote or to direct the vote: AWM is the investment adviser to the Fund. As the investment adviser to the Fund, AWM holds sole voting power over 1,272,296 shares of Common Stock of the Issuer (the Shares) held by SSLS. Greenhouse and Stettner are members of LS, the general partner of SSLS. Greenhouse and Stettner are also controlling principals of AWM.
	(ii) Shared power to vote or to direct the vote: 0
	(iii) Sole power to dispose or to direct the disposition of: AWM is the investment adviser to the Fund. As the investment adviser to the Fund, AWM holds sole investment power over 1,272,296 shares of Common Stock of the Issuer (the Shares) held by SSLS. Greenhouse and Stettner are members of LS, the general partner of SSLS. Greenhouse and Stettner are also controlling principals of AWM.
	(iv) Shared power to dispose or to direct the disposition of: 0
Item 5.	Ownership of 5 Percent or Less of a Class.
Item 6.	Ownership of more than 5 Percent on Behalf of Another Person.
	Not Applicable
Item 7.	Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
	Not Applicable
Item 8.	Identification and Classification of Members of the Group.
	Not Applicable
Item 9.	Notice of Dissolution of Group.
	Not Applicable

Item 10.

Certifications:

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

AWM Investment Company, Inc.

Signature:	Adam Stettner
Name/Title:	Executive Vice President
Date:	08/14/2025

FAQ

How many shares of INFU does AWM Investment Company, Inc. report owning?

AWM reports beneficial ownership of 1,272,296 shares of InfuSystem Holdings common stock.

What percentage of INFU does the 13G/A filing report for AWM?

The filing states the reported position represents 6.1% of the class.

Does AWM have voting or dispositive power over the INFU shares?

Yes; AWM reports sole voting power and sole dispositive power over the 1,272,296 shares held by SSLS.

Through what vehicle does AWM hold the INFU shares?

The shares are held by Special Situations Life Sciences Fund, L.P. (SSLS), for which AWM is the investment adviser.

Does the filing state AWM intends to change control of InfuSystem?

The certification states the securities are held in the ordinary course of business and were not acquired and are not held to change or influence control of the issuer.