[144/A] IONIS PHARMACEUTICALS INC SEC Filing

Rhea-AI Filing Summary

An affiliate of IONS filed an amended notice of proposed sales of the issuer’s common stock under Rule 144. The filing covers a planned sale of 3,977 shares of common stock through broker Stifel Nicolaus & Company Inc., with an aggregate market value of $323,490.00, to be sold on or about 01/22/2026 on the Nasdaq market. These shares were acquired as restricted stock units from the issuer on 01/13/2026 as equity compensation, with payment dated 01/07/2026. The notice also lists prior sales in the last three months by Shannon Devers totaling several tranches of common stock, each with disclosed dates, amounts, and gross proceeds.

Form 144 Filer Information	UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 144 NOTICE OF PROPOSED SALE OF SECURITIES PURSUANT TO RULE 144 UNDER THE SECURITIES ACT OF 1933
FORM 144/A

144/A: Filer Information

Filer CIK
Filer CCC
Previous Accession Number Of The Filing
Is this a LIVE or TEST Filing?	LIVE TEST
Submission Contact Information
Name
Phone
E-Mail Address

144/A: Issuer Information

Name of Issuer

SEC File Number

Address of Issuer

Phone

Name of Person for Whose Account the Securities are To Be Sold

See the definition of "person" in paragraph (a) of Rule 144. Information is to be given not only as to the person for whose account the securities are to be sold but also as to all other persons included in that definition. In addition, information shall be given as to sales by all persons whose sales are required by paragraph (e) of Rule 144 to be aggregated with sales for the account of the person filing this notice.

Relationship to Issuer

144/A: Securities Information

Title of the Class of Securities To Be Sold	Name and Address of the Broker	Number of Shares or Other Units To Be Sold	Aggregate Market Value	Number of Shares or Other Units Outstanding	Approximate Date of Sale	Name the Securities Exchange
Common Stock	Stifel Nicolaus & Company Inc 501 N Broadway St. Louis MO 63102	3977	323490.00	161974393	01/22/2026	Nasdaq

Furnish the following information with respect to the acquisition of the securities to be sold and with respect to the payment of all or any part of the purchase price or other consideration therefor:

144/A: Securities To Be Sold

Title of the Class	Date you Acquired	Nature of Acquisition Transaction	Name of Person from Whom Acquired	Is this a Gift?	Date Donor Acquired	Amount of Securities Acquired	Date of Payment	Nature of Payment *
Common Stock	01/13/2026	Restricted Stock Units	Issuer			3977	01/07/2026	Equity Compensation

* If the securities were purchased and full payment therefor was not made in cash at the time of purchase, explain in the table or in a note thereto the nature of the consideration given. If the consideration consisted of any note or other obligation, or if payment was made in installments describe the arrangement and state when the note or other obligation was discharged in full or the last installment paid.

Furnish the following information as to all securities of the issuer sold during the past 3 months by the person for whose account the securities are to be sold.

144/A: Securities Sold During The Past 3 Months

Name and Address of Seller	Title of Securities Sold	Date of Sale	Amount of Securities Sold	Gross Proceeds
Shannon Devers 1367 Gazelle Ct Carlsbad CA 92010	Common Stock	01/16/2026	8353	636626.00
Shannon Devers 1367 Gazelle Ct Carlsbad CA 92010	Common Stock	01/07/2026	44199	3756915.00
Shannon Devers 1367 Gazelle Ct Carlsbad CA 92010	Common Stock	11/25/2025	16777	1342160.00

144/A: Remarks and Signature

Remarks

Date of Notice

Date of Plan Adoption or Giving of Instruction, If Relying on Rule 10b5-1

ATTENTION:

The person for whose account the securities to which this notice relates are to be sold hereby represents by signing this notice that he does not know any material adverse information in regard to the current and prospective operations of the Issuer of the securities to be sold which has not been publicly disclosed. If such person has adopted a written trading plan or given trading instructions to satisfy Rule 10b5-1 under the Exchange Act, by signing the form and indicating the date that the plan was adopted or the instruction given, that person makes such representation as of the plan adoption or instruction date.

Signature

ATTENTION: Intentional misstatements or omission of facts constitute Federal Criminal Violations (See 18 U.S.C. 1001)

FAQ

What does the IONS Form 144/A filing by Shannon Devers disclose?

The filing shows that Shannon Devers, for whose account the securities are to be sold, has filed an amended notice to sell 3,977 shares of the issuer’s common stock under Rule 144, along with details of recent prior sales.

How many IONS shares are covered by the current planned sale?

The notice covers a proposed sale of 3,977 shares of common stock with an aggregate market value of $323,490.00, to be sold through Stifel Nicolaus & Company Inc. on or about 01/22/2026 on the Nasdaq exchange.

How did Shannon Devers acquire the IONS shares being sold in this Form 144/A?

The 3,977 shares to be sold were acquired as restricted stock units from the issuer on 01/13/2026, with the nature of payment listed as equity compensation and a payment date of 01/07/2026.

What prior IONS stock sales by Shannon Devers are reported in the last three months?

The filing lists prior sales of common stock by Shannon Devers over the past three months, including 8,353 shares on 01/16/2026 for gross proceeds of $636,626.00, 44,199 shares on 01/07/2026 for $3,756,915.00, and 16,777 shares on 11/25/2025 for $1,342,160.00.

What does the Form 144/A say about material nonpublic information and trading plans?

By signing the notice, the person for whose account the securities are to be sold represents that they do not know any material adverse information about the issuer’s current or prospective operations that has not been publicly disclosed. If relying on a Rule 10b5-1 trading plan or instructions, that representation applies as of the plan adoption or instruction date.

How many IONS shares are outstanding according to this Form 144/A?

The securities information section states that the number of shares of the issuer’s common stock outstanding is 161,974,393 shares.