[144] Ionis Pharmaceuticals, Inc. SEC Filing

Rhea-AI Filing Summary

Ionis Pharmaceuticals insider sale notice: This Form 144 shows a proposed sale of 10,000 shares of Ionis common stock through Stifel Nicolaus & Company, with an aggregate market value of $503,671. The filing reports the shares were acquired as restricted stock units on 01/15/2019 (16,802 units originally) and payment was in cash. The filer previously sold 10,000 shares on 08/05/2025 for $428,593. The company has 159,391,229 shares outstanding, so the proposed sale represents approximately 0.0063% of outstanding shares. The filer attests there is no undisclosed material information.

Positive

• Complete disclosure of broker, quantity, acquisition date, and prior sale within three months
• Insider attestation asserts no undisclosed material information, aligning with compliance expectations

Negative

• Insider sale reported (10,000 shares), which some investors monitor as a potential signal despite being small
• No Rule 10b5-1 plan date provided in the remarks section, so planned-trading status is not stated

Insights

Securities Analyst

TL;DR: Routine Form 144 filing reporting an insider sale of 10,000 shares valued at $503,671; small relative to outstanding stock.

The filing documents a proposed brokered sale of 10,000 Ionis shares via Stifel Nicolaus with an aggregate market value of $503,671. The securities were acquired as restricted stock units on 01/15/2019 and previously a sale of 10,000 shares occurred on 08/05/2025 for $428,593. Given 159,391,229 shares outstanding, the proposed sale is roughly 0.0063% of the float, which is immaterial from a market-cap perspective. The filing includes the standard insider attestation regarding material nonpublic information.

Corporate Governance Expert

TL;DR: Filing reflects compliance with Rule 144 disclosure for an insider sale; nothing in the record indicates regulatory or governance concerns.

The notice provides required disclosure elements: broker name and address, quantity, aggregate market value, acquisition date and nature (restricted stock units), and recent sales within three months. The inclusion of the prior sale on 08/05/2025 and the attestation statement supports procedural transparency. There are no statements of plan adoption dates for Rule 10b5-1 in the remarks section.

Form 144 Filer Information	UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 144 NOTICE OF PROPOSED SALE OF SECURITIES PURSUANT TO RULE 144 UNDER THE SECURITIES ACT OF 1933
FORM 144

144: Filer Information

Filer CIK
Filer CCC
Is this a LIVE or TEST Filing?	LIVE TEST
Submission Contact Information
Name
Phone
E-Mail Address

144: Issuer Information

Name of Issuer

SEC File Number

Address of Issuer

Phone

Name of Person for Whose Account the Securities are To Be Sold

See the definition of "person" in paragraph (a) of Rule 144. Information is to be given not only as to the person for whose account the securities are to be sold but also as to all other persons included in that definition. In addition, information shall be given as to sales by all persons whose sales are required by paragraph (e) of Rule 144 to be aggregated with sales for the account of the person filing this notice.

Relationship to Issuer

144: Securities Information

Title of the Class of Securities To Be Sold	Name and Address of the Broker	Number of Shares or Other Units To Be Sold	Aggregate Market Value	Number of Shares or Other Units Outstanding	Approximate Date of Sale	Name the Securities Exchange
Common Stock	Stifel Nicolaus & Company Inc 501 N Broadway St. Louis MO 63102	10000	503671.00	159391229	09/02/2025	Nasdaq

Furnish the following information with respect to the acquisition of the securities to be sold and with respect to the payment of all or any part of the purchase price or other consideration therefor:

144: Securities To Be Sold

Title of the Class	Date you Acquired	Nature of Acquisition Transaction	Name of Person from Whom Acquired	Is this a Gift?	Date Donor Acquired	Amount of Securities Acquired	Date of Payment	Nature of Payment *
Common Stock	01/15/2019	Restricted Stock Units	Issuer			16802	01/15/2019	Cash

* If the securities were purchased and full payment therefor was not made in cash at the time of purchase, explain in the table or in a note thereto the nature of the consideration given. If the consideration consisted of any note or other obligation, or if payment was made in installments describe the arrangement and state when the note or other obligation was discharged in full or the last installment paid.

Furnish the following information as to all securities of the issuer sold during the past 3 months by the person for whose account the securities are to be sold.

144: Securities Sold During The Past 3 Months

Name and Address of Seller	Title of Securities Sold	Date of Sale	Amount of Securities Sold	Gross Proceeds
Richard Geary 2855 Gazelle Ct Carlsbad CA 92010	Common Stock	08/05/2025	10000	428593.00

144: Remarks and Signature

Remarks

Date of Notice

Date of Plan Adoption or Giving of Instruction, If Relying on Rule 10b5-1

ATTENTION:

The person for whose account the securities to which this notice relates are to be sold hereby represents by signing this notice that he does not know any material adverse information in regard to the current and prospective operations of the Issuer of the securities to be sold which has not been publicly disclosed. If such person has adopted a written trading plan or given trading instructions to satisfy Rule 10b5-1 under the Exchange Act, by signing the form and indicating the date that the plan was adopted or the instruction given, that person makes such representation as of the plan adoption or instruction date.

Signature

ATTENTION: Intentional misstatements or omission of facts constitute Federal Criminal Violations (See 18 U.S.C. 1001)

FAQ

What does the Form 144 filed for IONS report?

The Form 144 reports a proposed sale of 10,000 Ionis common shares through Stifel Nicolaus with an aggregate market value of $503,671.

When were the shares being sold originally acquired?

The shares were acquired as Restricted Stock Units on 01/15/2019 and payment was in cash.

Has the filer sold any Ionis shares recently?

Yes. The filing discloses a sale of 10,000 shares on 08/05/2025 for $428,593.

How large is the proposed sale relative to Ionis' outstanding shares?

Ionis has 159,391,229 shares outstanding; the proposed sale of 10,000 shares is about 0.0063% of outstanding shares.

Which broker is handling the proposed sale?

The broker listed is Stifel Nicolaus & Company Inc, 501 N Broadway, St. Louis, MO 63102.