[144] Ionis Pharmaceuticals, Inc. SEC Filing

Rhea-AI Filing Summary

Form 144 filed for Ionis Pharmaceuticals (IONS) reports a proposed sale of 16,000 shares of common stock via Stifel Nicolaus with an aggregate market value of $962,371.00. The filing lists approximately 159,391,229 shares outstanding and an approximate sale date of 09/03/2025 on Nasdaq. The shares were acquired by option exercise on 07/01/2016 and the proposed payment method is cash. The filer reports no securities sold in the past three months.

Insights

Financial Analyst

TL;DR: This is a routine insider notice for a modest-sized sale relative to outstanding shares; no new financial results are disclosed.

The Form 144 documents a proposed sale of 16,000 shares valued at $962,371. The shares were acquired via option exercise in 2016 and are being sold through a broker on Nasdaq on or about 09/03/2025. With ~159.4 million shares outstanding, the sale represents a very small fraction of the float, suggesting limited direct impact on outstanding share count or liquidity. The filing primarily serves regulatory disclosure and does not provide operational or earnings information.

Corporate Governance Expert

TL;DR: The notice meets disclosure requirements; insider selling is documented but not large enough to indicate a governance red flag by itself.

The filer affirms no undisclosed material adverse information and notes the sale arises from a 2016 option exercise. The use of a recognized broker and the absence of other sales in the past three months are consistent with standard compliance practices. While insider sales warrant investor attention, the magnitude here appears routine and is unlikely to reflect a governance or disclosure concern absent other contextual facts.

Form 144 Filer Information	UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 144 NOTICE OF PROPOSED SALE OF SECURITIES PURSUANT TO RULE 144 UNDER THE SECURITIES ACT OF 1933
FORM 144

144: Filer Information

Filer CIK
Filer CCC
Is this a LIVE or TEST Filing?	LIVE TEST
Submission Contact Information
Name
Phone
E-Mail Address

144: Issuer Information

Name of Issuer

SEC File Number

Address of Issuer

Phone

Name of Person for Whose Account the Securities are To Be Sold

See the definition of "person" in paragraph (a) of Rule 144. Information is to be given not only as to the person for whose account the securities are to be sold but also as to all other persons included in that definition. In addition, information shall be given as to sales by all persons whose sales are required by paragraph (e) of Rule 144 to be aggregated with sales for the account of the person filing this notice.

Relationship to Issuer

144: Securities Information

Title of the Class of Securities To Be Sold	Name and Address of the Broker	Number of Shares or Other Units To Be Sold	Aggregate Market Value	Number of Shares or Other Units Outstanding	Approximate Date of Sale	Name the Securities Exchange
Common Stock	Stifel Nicolaus & Company Inc 501 N Broadway St. Louis MO 63102	16000	962371.00	159391229	09/03/2025	Nasdaq

Furnish the following information with respect to the acquisition of the securities to be sold and with respect to the payment of all or any part of the purchase price or other consideration therefor:

144: Securities To Be Sold

Title of the Class	Date you Acquired	Nature of Acquisition Transaction	Name of Person from Whom Acquired	Is this a Gift?	Date Donor Acquired	Amount of Securities Acquired	Date of Payment	Nature of Payment *
Common Stock	07/01/2016	Option Exercise	Issuer			16000	09/03/2025	Cash

* If the securities were purchased and full payment therefor was not made in cash at the time of purchase, explain in the table or in a note thereto the nature of the consideration given. If the consideration consisted of any note or other obligation, or if payment was made in installments describe the arrangement and state when the note or other obligation was discharged in full or the last installment paid.

Furnish the following information as to all securities of the issuer sold during the past 3 months by the person for whose account the securities are to be sold.

144: Securities Sold During The Past 3 Months

Nothing to Report

144: Remarks and Signature

Remarks

Date of Notice

Date of Plan Adoption or Giving of Instruction, If Relying on Rule 10b5-1

ATTENTION:

The person for whose account the securities to which this notice relates are to be sold hereby represents by signing this notice that he does not know any material adverse information in regard to the current and prospective operations of the Issuer of the securities to be sold which has not been publicly disclosed. If such person has adopted a written trading plan or given trading instructions to satisfy Rule 10b5-1 under the Exchange Act, by signing the form and indicating the date that the plan was adopted or the instruction given, that person makes such representation as of the plan adoption or instruction date.

Signature

ATTENTION: Intentional misstatements or omission of facts constitute Federal Criminal Violations (See 18 U.S.C. 1001)